Gene FRAY_c (S.moellendorffii)

FRAY_c

Species: S.moellendorffii
Alias: FRAY_c
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
FRAY_c.AA Protein None 372 None Fasta, JSON
FRAY_c.NA RNA None 1119 None Fasta, JSON
FRAY_c.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of FRAY_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase FRAY_c.AA FRAY 14-275 56 5.8e-171 535.58 In-house 1-277 (277) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-277/277
Sequence Identity: 56% (156 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCS-SNLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGGSCLHIMKAAYPDGF---
|.| | .|.| .|.|..|.|| ..| .|||  .||||    .||..|| . |.. .|||||  . ||||  .||.|| |  .|||| |||  .|.|.   
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

----EEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGD--RQRSRNTFVGTPCWMAPEVMEQIHGYDFKADIWSFG
    .|.||||.||..||.|.|.|..| ||||.|  ||||...|.| . |||||| | ..||  |. .| |||||||||||||||| |||||||||||||
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

ITALELAHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDRR-----FSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
|||.||| | ||. ||||||||. |||| || |. . |.      ...|||.||  || ||| ||||| .||||.||
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase FRAY_c.AA STE20 14-275 41 6.1e-130 437.99 In-house 1-288 (288) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-288/288
Sequence Identity: 41% (122 aa)

YQLLEEVGQGVSATVYRAMCISFKEI----VAIKSLDLEKCS---SNLDEIRKEAKTMSLINHPNVVRAYCSFVVE----HSLWVVMPYMAGGSCLHIMK
|.|||..||| . .||.| ... .|.    |||| ..||||.     ...| ||   |.  .|||.|. |.|....    ..||.||.|..|||.. |||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

AAYPDG-------FEEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFD--TGDRQRS--RNTFVGTPCWMAPEVMEQ--
. ...|       ..|. ||......|..|.|||... ||||.|  |||....| .|| ||||.| | .  . |  ..  ||||||||.||||||...  
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCME

--IHGYDFKADIWSFGITALELAHGHAPFSKYPPMKVLLMTL--QNAPPGLDYERD-RRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
   .|||.|.||||.||||.|.| |. |.....||....|..  || || |  .   ...|..|..... ||.||| |||||..||||.|.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-KPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase FRAY_c.AA YSK 14-275 44 1.5e-112 340.29 In-house 1-257 (257) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-257/257
Sequence Identity: 44% (116 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGGSCLHIMKAAYPDGFEEAV
.  .| .| |    || .     ...|||| .|||. .   . | .|    |    |.. . | |.    .||..| | .|||||  ||. |  .|.|  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVMEQ-IHGYDFKADIWSFGITALELAHG
||..|.  ||.|.|||    ||||.|  |.|.  .| .||.||||.. . ||  .   |||||||| ||||||  | . .||||||||| ||||.|.| |
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIK---RNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKG

HAPFSKYPPMKVLLMTLQNAPPGLDYERDRRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
. | ..| ||.|.     | || |    .| .||.||| ...||.||| .||.|. ||||.| 
EPPYCDYHPMRVMFLIPKNNPPKL---EGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase FRAY_c.AA STE 14-275 33 6.5e-112 378.11 In-house 1-359 (359) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-359/359
Sequence Identity: 33% (121 aa)

YQLLEEVGQGVSATVYRAMCI------SFKEI---------VAIKSLDLEKCS----------------SNLDEIRKEAKTMSLIN--HPNVVRAYCSFV
....|..|.| . |||.||..      . .|.         .||| ..||.|.                .....| || |.|.  |  |||.|. |....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VE-------HSLWVVMPYMAGGSCLHIMKAAYPDGFE------------EAVIATVLKDTLKA-LEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSA
.|       ..||..| ||.|||.  |.|  |  |..            | .||......||. |.|||.|. ||||.|  |||.     .|| ||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

CLFDTGD-------------RQRSRNTFVGTPCWMAPEVMEQ-----IHGYDFKADIWSFGITALELAHGHAPFSKYPPMKVLLMTLQN-----------
.| |...             .|  |||||||| ||||||..|      .|||.|.||||.|.|..|.| |. |.....||....|...|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----APPGLDYERD---------------RRFSKSFKEMIAMCLVKDPTKRPTAEKLLK--HSFF
     || |  . .               ...|..||. |. ||.||| |||||..|||  |.|.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase FRAY_c.AA MST 14-275 41 6.9e-91 289.12 In-house 1-254 (254) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-254/254
Sequence Identity: 41% (111 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMSLINHPNVVRAYCSFV--VEHSLWVVMPYMAGGSCLHIMKAAYPDGFEE
. ..|  |||    ||.| ... ..||||| .  .   . |.|| ||  .|.  . ...|. | |.    .  .| || | ..|| . |||.     . |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN---EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRT-LNE

AVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVMEQIHGYDFKADIWSFGITALELAH
. ||..|.|||. |.|||.   |||| |  |||..  |. || |||||..|.||   .. |||..|||.|||||| ..| .|| |||||| ||||.|.| 
QQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDT---MAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLGITAIEMAE

GHAPFSKYPPMKVLLMTLQNAPPGLDYERD-RRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
|. |.|   || .. |  |. ||..   .|  ..|  |   .. ||.|.| .|.||| ||.|.|.
GMPPYSDIHPMRAMFMIPQKPPPTF---KDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase FRAY_c.AA S_TKc 14-275 32 4.1e-90 306.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAG--GSCLHIMKAAYPDG---
|..|...|.|  ..||..  .. ..||||| ..        . ||.| . ..  .|||.|. | .|.  ..|..|| |. |  |. ....|   . |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FEEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVMEQIHGYDF-KADIWSFGITA
 | | ... ... ...||||.|.|| ||||.|  |||.|.   ||..|||... |          .||.||| .|||||.    ||.. |.|.||.|.. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

LELAHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDRRFSKSFKEMIAMCLVKDPTKRPTAEKLLK-------HSFF
 |.. |  ||.    |....  .               |...|..|  ||.|||.||||| ..|.       | .|
YEMLCGYPPFP---QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FRAY_c.AA PAKA 14-275 36 5.7e-77 262.03 In-house 1-260 (260) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-260/260
Sequence Identity: 36% (97 aa)

YQLLEEVGQGVSATVYRAMCISFKEI--VAIKSLDLEKCSSNLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGGSCLHIMKAAY--PDG-
|. .|..||| | .||.|  |. ..   |||| ..... ..  . |  | ..|   .|.|.|. . |..|.. ||||| ||.||.   . ..     .. 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPK-KELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

FEEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVMEQIHGYDFKADIWSFGITALE
..|. || |.. .|..||..|... ||||.|  |||....| .|. |||  | | .    |..||| |||| ||||||  . . || | |||| || |.|
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQ---EQQKRNTMVGTPYWMAPEVIRR-KQYDEKVDIWSLGIMAIE

LAHGHAPFSKYPPMKVLLMTLQN-APPGLDYERDRRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
.. |  |. ..|| . .    .| .|. .| .   ..|..|..  . || .|. .|..|..||.| |.
MIEGEPPYLNEPPLRAMYLIATNGKPDIKDPD---KWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase FRAY_c.AA KHS 14-275 41 5.8e-71 237.89 In-house 1-258 (258) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-258/258
Sequence Identity: 41% (111 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGGSCLHIMKAAYPDGFEEAV
|.||  || |    ||.|  |  .|..|.| . .|  . ..  | .|   |    |||.|  . |.. .  ||..| |  |||   | ..  |   .|  
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP--LSELQ

IATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEV--MEQIHGYDFKADIWSFGITALELAH
|| | ..||..|.||| .| .|||.|  |||. ..| .|| |||||| .  |  . .|   |.||| ||||||  .|.  ||.   |||. ||||.||| 
IAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKS---FIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAE

GHAPFSKYPPMKVL-LMTLQN-APPGLDYERDRRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
   |.    ||..| |||  |  || |  .  ...|..| . . |.|.|.| |||||||||.| |.
LQPPMFDLHPMRALFLMTKSNFQPPKL--KDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase FRAY_c.AA Pkinase 14-275 30 1e-69 242.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRK---EAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGG----SCLHIMKAAYP
|.... .|.| ...||... ..  .|||.| ..... .|. |...    |.. |  .||||.|| |..|  . ....||.|. ||    .  ..... . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DGF--EEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAI----KLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVMEQIHGYDFKADIW
 .|  .| ..  ... .|..|||.|..| ||||.|  |||||.|| |    |..|||.....     ...  .||.||| .|||||     .|. |.|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGITALELAHGHAPFS------KYPPMKVLLMTLQNAPPGLDYERDRRFS-----------------KSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
|.|..  |.. |. ||.      .   .....     .|.  |.. ... |                 ...|. |  || |||.|||||| .|.| .|
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase FRAY_c.AA SLK 14-275 36 3e-65 219.07 In-house 1-259 (259) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-259/259
Sequence Identity: 36% (97 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGGSCLHIMKAAYPDGFEEAV
.... |.| |    ||.|     | . | |......   .|..   |   .| ..|||.|. | .. ... ||... . .||    ||      . .|  
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKD-EEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIM-VELEHPLTEDQ

IATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVM----EQIHGYDFKADIWSFGITALEL
|. | | .. ||..||..  ||||.|  |||.  .| ..| |||||| .  | ..   | ||.||| ||||||.     . . ||.||||||.||| .|.
IQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQK---RDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEM

AHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDRRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
|..  | .   ||.|||   .  || |  |.  ..||.||...  |||||| .|.|...|..| ..
AQMEPPHHEMNPMRVLLKIQKSEPPTL--EQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase FRAY_c.AA MSN 14-275 36 2.7e-64 211.14 In-house 1-265 (265) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-265/265
Sequence Identity: 36% (99 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMS-LINHPNVVRAYCSFV------VEHSLWVVMPYMAGGSCLHIMKAAYP
..| | ||.|    ||. .     ...||| .|...   . .||..|   .    .| |..  |  |.       .| ||.|| . . ||   ..| .  
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE--DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

DGFEEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQRSRNTFVGTPCWMAPEVM----EQIHGYDFKADIWSF
.   |  || . .. |. | .|| |  ||||.|  |.|.  |  .|| |||||| |  |  |   ||||.||| ||||||.    .    ||...|.|| 
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSV

GITALELAHGHAPFSKYPPMKVLLMTLQNAPPGLDYERDRRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
||||.|.| |. |  .  ||. |.. . |.|| |     ...|| |.. .  ||.|.  .||..|..|||.| 
GITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK---SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase FRAY_c.AA STLK 14-226 30 2.3e-54 185.52 In-house 1-222 (313) Show / Hide 
Range on Protein: 14-226
Range on HMM: 1-222/313
Sequence Identity: 30% (69 aa)

YQLLEEVGQG---VSATVYRAMCISFKEIVAIKSLDLEKCSS-NLDEIRKEAKTMSLINHPNVVRAYCSFVVEHSLWVVMPYMAGGSCLHIMKAAYPDGF
| .|.. |..      ..| .  .  .. |..|   .. |.   .  . ||  . .| .|||..  . .|... ..||.|. |. |||  . .  ...|.
YECLRYMGNCFDNMMYVHYARHKP-TGDYVTVKKFNMDQCMEEMYCLFQKECHNSRLMQHPNIFEYWTCFICKNWIWVIMHFMCYGSCKDLLCTYCHWGM

EEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDRQR------SRNTFVGTPCWMAPEVMEQ-IHGYDFKADIWSF
 | .|| .... .||| |.|. . |||.||   |||.. |  .|  |     .   | |.|       ...|.  . | |||| .| .|||| |.||.| 
NEKAIAMIHRGVVKALDYIHQMHYIHRSVKAKHILISTDGKVHLSGFRHCMWMIEHGQRHRCVFDFPNFHSFKQLY-WLAPEVLNQNLHGYDAKSDIYSV

GITALELAHGHAPFSKYPPMKVLL
|||..|.| |. ||.. .|.. |.
GITCCEMANGCMPFKDMHPTQMLH
Kinase FRAY_c.AA Pkinase_Tyr 14-205 25 3.5e-27 92.7 Pfam 1-203 (270) Show / Hide 
Range on Protein: 14-205
Range on HMM: 1-203/270
Sequence Identity: 25% (52 aa)

YQLLEEVGQGVSATVYRAMCI----SFKEIVAIKSLDLEKCSSN---LDEIRKEAKTMSLI-NHPNVVRAYCSFV-VEHS--LWVVMPYMAGGSCLHIMK
 ..... |.|   .||.. .     . |  ||.|.|  |....    ...  .|||.|. . .|||.|| |   .  . .  ...||.||..|. |.  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AA--YPDGFEEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDTGDR-QRSRNTFVGTPCWMAPEVMEQIHGYDFKADI
.    .. .    .     .  |..|||.... ||||.   |.|...|. .| .||| .  .....   . . ..      |||||..     .  | |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK-FTTKSDV

WSFGIT
||||..
WSFGVL
Kinase FRAY_c.AA TyrKc 14-275 22 3.4e-19 71.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-275
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YQLLEEVGQGVSATVYRAMCISFKEIVAIKSLDLEKCSSNLDEIRKEAKTMSLI--NHPNVVRAYCSFVVE-------HSLWVVMPYMAGGSCLHIMKAA
 .|... | |   .||... .   . ||.|.|  ..    . ....||. |. .  .|||.|| |   . .       . |..|| ||..|....  .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

YPDGFEEAVIATVLKDTLKALEYLHRHGHIHRDVKVWNILIDSNGAIKLGDFGVSACLFDT---GDRQRSRNTFV----GTP--C---WMAPEVMEQIHG
 |. .  .       .  .  ||||... ||||    |.|...|. .| .||| |  . |    |   ..    .    |.       |||||.. . . 
RPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

YDFKADIWSFGITALELAHGHAPFSKY-----PPMKVLLMTLQNA----PPGLDYERDRR----FSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
. .| |.||||..  |.    ..          . . ..  ...     .|  ||          ..   ... .|   || .||| . .  |..|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase FRAY_c.AA STLK 242-275 47 5.4e-12 37.64 In-house 280-313 (313) Show / Hide 
Range on Protein: 242-275
Range on HMM: 280-313/313
Sequence Identity: 47% (16 aa)

RRFSKSFKEMIAMCLVKDPTKRPTAEKLLKHSFF
||||. | | .. || ..| .|. | .|. ||||
RRFSTHFHEFMEQCLQYNPEQRWSASHLMSHSFF