Gene FRAY_d-1 (S.moellendorffii)

FRAY_d-1

Species: S.moellendorffii
Alias: FRAY_d-1
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
FRAY_d-1.AA Protein None 367 None Fasta, JSON
FRAY_d-1.NA RNA None 1104 None Fasta, JSON
FRAY_d-1.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of FRAY_d-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase FRAY_d-1.AA FRAY 21-283 48 4.3e-136 425.36 In-house 1-277 (277) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-277/277
Sequence Identity: 48% (135 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCR-SDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGL---
|   | || |  |.||.|.|.|| | . || |.||||    .||...| |  ..  |||||.    |.|   ||.|| |  .|||| ||.   | |    
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

----DEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFD--CYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADIWSL
    || ..||.|.| ||.|.|.| .| ||||.||||||..  | . . |||||| | .    .|.   |.|| ||||||||||.. | |||  |||||.
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCV-RHTFVGTPCWMAPEVMEQVHGYDFKADIWSF

GITALELAQGHAPLSDLPPMKMVLVELSGPPPTLEPERAKA-----FSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
||||.||| | ||  ..||||  .  | ..||.|| .  .      ...|||. .  ||||. |||||| .|||| ||
GITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase FRAY_d-1.AA STE20 21-283 39 2e-114 386.47 In-house 1-288 (288) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-288/288
Sequence Identity: 39% (116 aa)

YRVLEEIGHGRNATVHRALCVPRGEI----VSIKSIDLEKCR---SDLDEVRREAQTLSLIDHPNVVAALALFIVG----QRLWVVMPYMAAGSCLTIMR
|  ||.||.|   .|..| ..| ||.    | || ..||||     .....  | . ..  .|||.|. .  ....    . ||.||.|...||.. ||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---VARP----YGLDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFD--CYNRQIA-RRTTFAGTPCWMAPEVLDPV-
   .       . ..|. .|...||.|..||||| .. ||||.||.|||....| ||| ||||.| | .       .. .| || |||.||||||.  . 
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCME

---CGYDCSADIWSLGITALELAQGHAPLSDLPPMKMVLVELSG--PPPTLEPERA-KAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
    |||. .|||||||||.|.| |. |..|..||.. .  ...  |||||. .   . .|..|.|||. ||||. .||||| .|||| |.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-KPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase FRAY_d-1.AA YSK 21-283 42 1.7e-102 309.41 In-house 1-257 (257) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-257/257
Sequence Identity: 42% (112 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGLDEPL
.  .| || |    |  .  .  ...| || ||||.   . . . .| | ||  | |..   .. .  .  ||..| | . ||||  |.     ..||. 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

VATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDP-VCGYDCSADIWSLGITALELAQ
.|..||| ||.|||||    ||||.|| |.|.  || |||.||||.. . |    .  .| ||.||| ||||||    | .||  ||||||||||.|.| 
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITD----TQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAK

GHAPLSDLPPMKMVLVELSGPPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
|. |..|. ||.      . .||.|| .    .||.||.||.||| |. ..||.|  |||| | 
GEPPYCDYHPMRVMFLIPKNNPPKLEGR---SYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase FRAY_d-1.AA STE 21-283 30 1.4e-97 330.45 In-house 1-359 (359) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-359/359
Sequence Identity: 30% (110 aa)

YRVLEEIGHGRNATVHRALCV------PRGEI---------VSIKSIDLEKCR----------------SDLDEVRREAQTLSLID--HPNVVAALALFI
.. .|.||.|   ||..|...      . ||.         . || ..||.|.                ...... .| ....  .  |||.|  .  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG-------QRLWVVMPYMAAGSCLTIMRVARPYGLD------------EPLVATVLRECLKA-LDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSA
..       . ||..| ||..||.  |..     | .            |...|...|..||. |.||| |. ||||.|..|||.     ||| ||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

CLFD-CYNR----------QIA-RRTTFAGTPCWMAPEVLDP-----VCGYDCSADIWSLGITALELAQGHAPLSDLPPMK-MVLVELS-----------
.| | . |            .. .|.||.||| ||||||...     . |||...||||||.|..|.| |. |..|..||. | .   .           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GPPPTLEPERA---------------KAFSKSFKDFVACCLQKEASKRPTAGKLLK--HGFF
   ||||.|...                 . .|..||||.. ||||. .||||| .|||  | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase FRAY_d-1.AA S_TKc 21-283 31 6.2e-80 272.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAA--GSCLTIMRVARP----Y
|..|..||.|  ..|...  .  |.|| || |.        . .||| | |.  .|||.|  .  |   ..|..|| |.    |. .....  ..    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

GLDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDC-SADIWSLGIT
...|  .. .... ..||.|.| || ||||.|  |||.|.   .|..|||... |           ||| ||| .||||||    ||.. ..|.||.|..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

ALELAQGHAPLSDLPPMKMVLVELSGPPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLK-------HGFF
  |.. |  | .      ... .. |             |...|||.  ||||. .||||| ..|.       | .|
LYEMLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FRAY_d-1.AA MST 21-283 40 5.5e-79 250.69 In-house 1-254 (254) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-254/254
Sequence Identity: 40% (107 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFI--VGQRLWVVMPYMAAGSCLTIMRVARPYGLDE
. ..| .| |    |..|..   |.|| || .  .   .||.|   |  ...  . ...|   . ..    . .| || | ..|| . ||. ..   | |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN---EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMK-ITQRTLNE

PLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADIWSLGITALELA
   |..|.  |. |.|||.   |||| ||||||... |  || |||||..|.|      | | |. |||.||||||.  . .||| ||||||||||.|.|
QQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDT----MAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLGITAIEMA

QGHAPLSDLPPMKMVLVELSGPPPTL-EPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
 |. |.||. ||       . ||||. .||.   .|  | |||. ||||. ..|.||  ||.| |.
EGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQ---WSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase FRAY_d-1.AA KHS 21-283 40 1.2e-65 219.79 In-house 1-258 (258) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-258/258
Sequence Identity: 40% (107 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGLDEPL
| .|  .| |    |..|  .  .|.. .| | .|    |.  . .|   .    |||.||    ..  ..||..| |  .||   | .|  |  | |  
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP--LSELQ

VATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEV--LDPVCGYDCSADIWSLGITALELA
.| | || |..|.||| .| .|||.|  |||. ..| ||| |||||| .       ||.|  | ||| ||||||   .   ||.   |||..||||.|||
IAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITAT----IAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELA

QGHAPLSDLPPMK-MVLVELSG-PPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
    |. || ||. . |.  |.  ||.|. .. | .|..| .||  .| |.. ||||| |||.| |.
ELQPPMFDLHPMRALFLMTKSNFQPPKLK-DKHK-WSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase FRAY_d-1.AA MSN 21-283 36 5.1e-64 210.21 In-house 1-265 (265) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-265/265
Sequence Identity: 36% (100 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLS-LIDHPNVVAALALFI------VGQRLWVVMPYMAAGSCLTIMRVARP
. . | .| |    |.. . |  |... || .|...   . .|.. |   |     | |...    ||        ..||.|| . .|||   ... .. 
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVRE--DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

YGLDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVL----DPVCGYDCSADIWS
  | |  .| . || |. | .|| |  ||||.|  |.|. .   ||| |||||| |    .| . || || ||| ||||||.    .| . ||  .|.||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQL----DRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS

LGITALELAQGHAPLSDLPPMKMVLVELSGPPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
.||||.|.| |. || |. ||. ... .  |||.|    .| .|| |..|.  || |. ..||.....|||.| 
VGITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK---SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase FRAY_d-1.AA SLK 21-283 35 1.4e-62 209.92 In-house 1-259 (259) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-259/259
Sequence Identity: 35% (95 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLTIMRVARPYGLDEPL
. .. |.| |    |..|    .. .   |.|....   .|..   | . || ..|||.|  .  . . ..||... . . |   .|| |    .| |. 
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKD-EEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIM-VELEHPLTEDQ

VATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCG------YDCSADIWSLGITA
.. | .. . ||..|| .  ||||.||||||. . |.|.| |||||| .     ... .| || ||| ||||||.  .|       ||. ||||||||| 
IQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKN----KHTMQKRDTFIGTPYWMAPEVV--MCETFKDQPYDYKADIWSLGITL

LELAQGHAPLSDLPPMKMVL-VELSGPPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
.|.||.  | ... ||...| .. | ||  ..| .   .||.||||.  ||.|.. .|.|. .|..| ..
IEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSH---WSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase FRAY_d-1.AA PAKA 21-283 35 1.6e-59 204.02 In-house 1-260 (260) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-260/260
Sequence Identity: 35% (96 aa)

YRVLEEIGHGRNATVHRALCVPRGEI--VSIKSIDLEKCRSDLDEVRREAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAGSCLT--IMRVAR-PYG
|...|.|| |   .| .|  .  ..   | || .....  .  . .  |  ..    |.|.|  .  ..|   ||||| ||..| |||  |  ...   .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGG-CLTDVITQCCNIQCN

-LDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADIWSLGITA
 .||  .| |.||||..|...| .. ||||.|  |||... | ||. |||  | |    ...  .|.|  ||| ||||||.     ||   ||||||| |
YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQL----TQEQQKRNTMVGTPYWMAPEVIR-RKQYDEKVDIWSLGIMA

LELAQGHAPLSDLPPMK-MVLVELSGPPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
.|.. |  |  . || . | |.   | |. ..|..   .|..|.||.. ||...  .|..| .||.| |.
IEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDK---WSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase FRAY_d-1.AA NinaC 21-283 36 1.6e-56 194.13 In-house 1-267 (267) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-267/267
Sequence Identity: 36% (102 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLD-EVRREAQTL-SLIDHPNVVAALALF-----IVGQRLWVVMPYMAAGSCLTIMR--VA
. . |.|| | .. | ...    |.|. .|  .     .|.| |.  | ..|  . ||||||    ..     ..| .|| || | . ||   . .    
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYI---HDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLK

RPYGLDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCS----ADI
.   ..|...| .|.| . .|  || .  ||||||  |||  . ||||| |||||| |         || |  ||||||||||      || .    .|.
CGRRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQL----DSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDV

WSLGITALELAQGHAPLSDLPPMKMVLVELSGPPPTLEPERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
||||||| ||. |  |. |. ||..       |||||   .    .. | ||.  || |.. |||.   .|.| | 
WSLGITAIELGDGDPPFADMHPMRAMFKIPRNPPPTL--MHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase FRAY_d-1.AA Pkinase 21-283 27 2e-56 198.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRR---EAQTLSLIDHPNVVAALALFIVGQRLWVVMPYMAAG----SCLTIMR--VA
|.... || |  ..| ..  .  |.|| .| |.... .|. |. .|   |.| .  ..|||.|  .  |  ......||.|.  |    .  ....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPYGLDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGV----KLGDFGVSACLFDCYNRQIARRTTFAGTPCWMAPEVLDPVCGYDCSADI
... ..|  .  .... |..|.|.| .| ||||.|  |||.|..| .    |..|||.....    .      |||.||| .|||||.    .|. ..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGITALELAQGHAPLSDL------PPMKMVLVELSGPPPTLEP-----------------ERAKAFSKSFKDFVACCLQKEASKRPTAGKLLKHGFF
||.|..  |.. |. | ..        .|.|.   ...|..  .|                 .. .. |...|||. .||.|  .|||||  .|.| .|
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase FRAY_d-1.AA TyrKc 21-283 21 6.8e-16 34.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-283
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YRVLEEIGHGRNATVHRALCVPRGEIVSIKSIDLEKCRSDLDEVRREAQTLSLI--DHPNVVAALALFIVG-------QRLWVVMPYMAAGSCLTIMRVA
 . ....|.|   .|...      . | .|..  ..    . . .|||. .. .  .|||.|. ..  . .       . |..|| ||. |...   |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RPYGLDEPLVATVLRECLKALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVSACLFDC--------YNRQ----IAR--RTTFAGTPCWMAPEVLDP
||  |  .          .  .||| .. ||||  | |.||.  . || .||| |  . |         | |.     ..           |||||..  
RPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-----WMAPECI--

VCG-YDCSADIWSLGITALELA-QGHAPLSD-----LPPMKMVLVELSG----PPPTLEPERAKA----FSKSFKDFVACCLQKEASKRPTAGKLLKHGF
  | .    |.|| |..  |.   |  | ..     ...  ..    .|    .||  .           ..   .   .| . ....|||   .  | .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

F
|
F
Kinase FRAY_d-1.AA Pkinase_Tyr 21-103 20 5.2e-13 44.69 Pfam 1-93 (270) Show / Hide 
Range on Protein: 21-103
Range on HMM: 1-93/270
Sequence Identity: 20% (19 aa)

YRVLEEIGHGRNATVHRALCV----PRGEIVSIKSIDLEKCRSD---LDEVRREAQTLSLI-DHPNVVAALALFI-VGQR--LWVVMPYMAAGS
 . ....|.|   .|... .       .  | .|..  |.. ..   ...  |||.... . .|||.|  ..  .  |.   ...||.||. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD
Kinase FRAY_d-1.AA Pkinase_Tyr 130-166 43 0.000147 16.06 Pfam 122-158 (270) Show / Hide 
Range on Protein: 130-166
Range on HMM: 122-158/270
Sequence Identity: 43% (16 aa)

KALDYLHFHGHIHRDVKAGNILVDQHGGVKLGDFGVS
|...||. .. ||||. | |.||.  . || .||| .
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA