Gene MST-2 (S.moellendorffii)

MST-2

Species: S.moellendorffii
Alias: MST-2
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
MST-2.AA Protein None 760 None Fasta, JSON
MST-2.NA RNA None 2283 None Fasta, JSON
MST-2.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of MST-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MST-2.AA STE20 187-441 53 1.3e-154 519.97 In-house 1-288 (288) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-288/288
Sequence Identity: 53% (153 aa)

YDLLNQLGKGSYGAVYKARDRRTSEF----VAIKVISLTEGE---EGYDEIRGEIEMLQQCNHPNVVRYLGSYQGE----EYLWIVMEYCGGGSVGDLMS
|.|| ..|.||||.||||....| |     ||||...| . .   .  ..|  || ...||.|||.|.|.|||. .    . ||||||||||||. |.|.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---ITDE-----PLEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTR----TMS-KRNTFIGTPHWMAPEVIQE----
   ...      |..|.||||||||.|.||.|||.  ..|||||..||||||.||||| ||||.||||.    ||. |||||.||| ||||||||.    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-SRYDGKVDVWALGVSAIEMAEGLPPRSNVHPMRVLFMIS--REPAPMLED--KEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
 . || |.|.|.||  ||||||| || ...||||..|||   ..| | |.|  ..|||  |||||.|||.|.|  ||||. ||.|.||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MST-2.AA MST 187-441 56 1.3e-150 482.05 In-house 1-254 (254) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-254/254
Sequence Identity: 56% (145 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQ--GEEYLWIVMEYCGGGSVGDLMSITDEPLEEV
.|..  || |||| |||| .. |.. ||||...    .|  .||  || ..|||. ...|.| |||    .. .||||||||.||| |.| ||. .| |.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV---NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

QIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQESRYDGKVDVWALGVSAIEMAEGLPPR
||| |.. .|.||.|||   |.||||| ||||| . || || ||||..||| || ||||.|||| |||||||||. || |.| |.|| .||||||| || 
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPY

SNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
|..||||..|||   | | . | |.||  | |||.|||.|.| .|.||. |||| ||
SDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase MST-2.AA YSK 187-441 51 5.6e-143 433.54 In-house 1-257 (257) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-257/257
Sequence Identity: 51% (134 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQGEEYLWIVMEYCGGGSVGDLMSI-TDEPLEEVQ
.  .   |.||.| |||. |.|| . ||||.| | . |.  . |  ||  | ||  |.. .|.|||     |||.||||||||. |||      ...| .
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQE--SRYDGKVDVWALGVSAIEMAEGLPP
|| | || |||| |||   |.|||||  |.||.|.|.|||.|||||.|.| |. |||||.||| |||||||..  | || |.|.| ||. |.||| |.||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

RSNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
.. .|||||.| |  .. | ||. ...|  | .||. || |.|. ||.|  || ||||
YCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase MST-2.AA STE 187-441 37 4.6e-127 428.43 In-house 1-359 (359) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-359/359
Sequence Identity: 37% (137 aa)

YDLLNQLGKGSYGAVYKARDR------RTSEF---------VAIKVISLTEGE----------------EGYDEIRGEIEMLQQCN--HPNVVRYLGSYQ
.... ..|||..| ||||...      .| |          .|||...| . .                |  ..|  ||.....||  |||.|.|.|.| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

GE-------EYLWIVMEYCGGGSVGDLMS---ITDEPLE----------EVQIAYICREALKG-LAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAA
 |       ..|||.|||..|||. |..    .. .||           | |||||||. ||| |.|||   ..|||||..||||     ||| ||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTR---------------TMS-KRNTFIGTPHWMAPEVIQESR------YDGKVDVWALGVSAIEMAEGLPPRSNVHPMRVLFMISRE-----------
|||                ||. |||||.||| ||||||||  .      || |.|.| ||  .||||.| || .. ||||..||| ..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PAPMLED-----------------KEKWSLVFHDFVAKCLTKEPRLRPTATALLQ--HKFI
    | | |.|                 ..|||  |.||..|||.|.|. ||||. ||.  |.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MST-2.AA KHS 187-441 54 7e-118 397.92 In-house 1-258 (258) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-258/258
Sequence Identity: 54% (142 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQGEEYLWIVMEYCGGGSVGDLMSITDEPLEEVQI
|.|| ..| | || |||||| ...| .|.||| . | ..    |  || |...| |||.| | |||  .. |||.||||||||. |.  .|  ||.|.||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM-EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVT-GPLSELQI

AYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQESR---YDGKVDVWALGVSAIEMAEGLPP
||.|||.|.||.|||.  |.|||||| |||||.||.||| ||||.||.| |..||  ||||| ||||||    |   |.   |.||.|. |||.||  ||
AYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPP

RSNVHPMRVLFMISREP--APMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
  ..||||.||....     | |.||.|||  ||.||  .|||.|. ||||. ||||.|.
MFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase MST-2.AA PAKA 187-441 43 1.9e-108 366.62 In-house 1-260 (260) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-260/260
Sequence Identity: 43% (113 aa)

YDLLNQLGKGSYGAVYKARDRRTSEF--VAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQGEEYLWIVMEYCGGGSVGDLMSITDE----P
|. ....|.|. |.||.| ...| .   ||||.. . . .   . |  || .. .|.|.|.|.|. ||  .. ||.|||| .||.  |. . ...    .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

LEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQESRYDGKVDVWALGVSAIEMAEG
..| ||||.||| |.|| ..|.   .|||||  ||||  .|.||. ||| .||||.  .||||  ||| |||||||.   || |||.| ||. ||||.||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

LPPRSNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
 ||  |  | | .. |. . .| . |..|||  |.||..||| .... |..|. ||.| |.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MST-2.AA MSN 187-441 50 4e-103 341.39 In-house 1-265 (265) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-265/265
Sequence Identity: 50% (134 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQ-CNHPNVVRYLGSY------QGEEYLWIVMEYCGGGSVGDLMSIT-D
..| . .|.| || ||| |  .|....||||....| ||  .||. || ||..  .| |.. | | .        .. ||.|||.|| ||| ||.  | .
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEE--EEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKG

EPLEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQ-----ESRYDGKVDVWALGVS
. | |  ||||||| |.|||.||.   .|||||| |.|||.. |||| ||||.||| ||. .|||||||| |||||||.     .  || . |.|..|. 
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIEMAEGLPPRSNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
||||||| ||  ..|||| ||.| |.|.| |   .|||  ||.|. ||| |.   ||.. ..|.| ||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase MST-2.AA PAKL 187-441 45 4.5e-102 345.41 In-house 1-256 (256) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-256/256
Sequence Identity: 45% (116 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQGE-EYLWIVMEYCGGGSVGDLMSITDEPLEEVQ
. .   || ||||.||||  . |    |||||...|  |   .|  ||..|  |. ||.| | || | .   .|| |.||  ||. |.| ..   |.| |
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNE-IKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQ

IAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMS-KRNTFIGTPHWMAPEVIQESRYDGKVDVWALGVSAIEMAEGLPPR
|. | . .|||| |||    .|||||  ||||.| . ||. ||||  ||  . .   |  |||| |||||.|    |. |.|.| ||. |||||.|.|| 
ISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPH

SNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
. . ||| . || . | | . .  .||  | ||.|.|..| |  |. .  || | ||
YDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase MST-2.AA S_TKc 187-441 34 4.9e-99 336.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQGEEYLWIVMEYCGG--GSVGDLMSITDEP----
|..|...|||..| |||.|...| . ||||.|.        . || ||..|.. .|||.|......|  ..|..|||||.|  |.. |..     .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQESRYDG-KVDVWALGVSAIEMA
 . | ........ ...|.|.|    .|||.|  ||||.|  ..|..|||.|.||       .||.|||..|||||.    |.. |.|.|..|.  .||.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

EGLPPRSNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQ-------HKFI
 | || .    | ..| . .            |  . ||. |||.|.|. ||||  .||       | ..
CGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MST-2.AA SLK 187-441 43 3.8e-96 324.86 In-house 1-259 (259) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-259/259
Sequence Identity: 43% (112 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQCNHPNVVRYLGSYQGEEYLWIVMEYCGGGSVGDLMSITDEPLEEVQI
....  || | .| ||||... .. | | |.| . ..||  | .  ||..| .|.|||.|. ...|  .. ||...|.|.|| |  .|   ..||.| ||
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMV-EIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQI

AYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVI-----QESRYDGKVDVWALGVSAIEMAEGL
.|.|.. . .| .||    .|||.| ||||.| .|.|.| ||||.|....|| || |||||| ||||||.     ..  || |.|.|.||.  ||||.. 
QYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQME

PPRSNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
|| ... |||||. | .   | ||   .||  |.||. ||| |.|. |.|.  |.||...
PPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase MST-2.AA NinaC 187-441 43 8.3e-92 311.31 In-house 1-267 (267) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-267/267
Sequence Identity: 43% (117 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQ-CNHPNVVRYLGSYQ-----GEEYLWIVMEYCGGGSVGDLMSI---T
.      ||| || |.|. ...  . .|.|.      ..   ||  |   |.. |.||||||. | |      . . ||.||||| |||| |.       
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYI--HDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKC

DEPLEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVI-----QESRYDGKVDVWALGV
.. ..|  |||| .||. ||  ||    .|||.|| |||||  | ||| |||| |||. |  .||| .||| |||||||      .. ||   |||.||.
GRRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGI

SAIEMAEGLPPRSNVHPMRVLFMISREPAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
 |||.. | ||  . |||| .| | | | | |   |.|.  | ||. .||.|.   ||. . .|.|.||
TAIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase MST-2.AA Pkinase 187-441 31 4.3e-82 283.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIR---GEIEMLQQCNHPNVVRYLGSYQGEEYLWIVMEYCGGG----SVGDLMS-ITD
| .. ..|.||.| |||.... |.. ||.|.|.. . ... |...    ||.... .||||.||...... . ....|||||.||    .  |..|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EPL--EEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEV----KLGDFGVAAQL-TRTMSKRNTFIGTPHWMAPEVIQ-ESRYDGKVDVWAL
 ..  .| ..  .... |.||.|.|.   .|||.|  |||. ..|..    |..|||.|.|. .   |  .|| |||..||||||.  . |. |||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVSAIEMAEGLPPRSNV----HPMRVLFMISREPAPMLEDKEKWS---------------------LVFHDFVAKCLTKEPRLRPTATALLQHKFI
|.  .||. | || ..     . .. ..|| |   | |.  . |.                       . ||. .||.| |  ||||. .|||...
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MST-2.AA Pkinase_Tyr 187-398 27 1.3e-32 111.04 Pfam 1-231 (270) Show / Hide 
Range on Protein: 187-398
Range on HMM: 1-231/270
Sequence Identity: 27% (65 aa)

YDLLNQLGKGSYGAVYKARDR----RTSEFVAIKVISLTEGEEG--YDEIRGEIEMLQQC-NHPNVVRYLGSYQ-GEEY--LWIVMEYCGGGSVGDLMSI
  .. .||.|..| |||.. .     |   ||.|..  .  .|    ..   |.... |  .|||.||..|     .|   ..|||||. .|.  |    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T---DEPLEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQL-----TRTMSKRNTFIGTPHWMAPEVIQESRYDGKVDVW
    ..||   ..  .|..  ||..||...  .|||.   |.|.||.. || .||| |  .       . .. ..      |||||.|.....  | |||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGKFTTKSDVW

ALGVSAIEMAE-GLPP-RSNVHPMRVLFMI-SR
. ||   |.   |  |   .. . .|. .|  .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED
Kinase MST-2.AA TyrKc 187-441 23 1.5e-29 105.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 187-441
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YDLLNQLGKGSYGAVYKARDRRTSEFVAIKVISLTEGEEGYDEIRGEIEMLQQC--NHPNVVRYLGSYQGE-------EYLWIVMEYCGGGSVGDLMSIT
  |. .|| | .| |||.. .   . ||.|..          ... |.... .   .|||.|| .|    .       | |.|||||. .|.  |    .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DEPLEEVQIAYICREALKGLAYLHAIFKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRT----MSKRNTFI----GTP-----HWMAPEVIQESRYDGK
 . |   .  ..|  . .| .|||    .|||.   |.|..|.. || .||| .  ..       ||         |.       |||||.|.....  |
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDVWALGVSAIEMAE-GLPPRSN-----VHPMRVLFMISREPAPMLEDK-------EKWSLVFHDFVAKCLTKEPRLRPTATALLQHKFI
 |||. ||   |.   | .| ..     . . .|.  . .   ..  .        .  . ..     .|   .|  ||| ...  |...
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF