Gene IRAK-0_ab (S.moellendorffii)

IRAK-0_ab

Species: S.moellendorffii
Alias: IRAK-0_ab
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_ab.AA Protein None 294 None Fasta, JSON
IRAK-0_ab.NA RNA None 885 None Fasta, JSON
IRAK-0_ab.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_ab.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-0_ab.AA TKL 21-285 22 5.3e-67 228.9 In-house 1-364 (364) Show / Hide 
Range on Protein: 21-285
Range on HMM: 1-364/364
Sequence Identity: 22% (85 aa)

LGTGSFGTVYKGKLDD---------GTTVAIKKANNGN-----------------------APRIQ---QFLNEVT-ILSKVNHRNLVKMLGCCIEREV-
.| |.||.|||||.           |..||.|| .  |                       .| ..   .|..|.. ..|. .| |.|...|.|.. .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PLLVYEFVPRGTLYEHLHRRGDTLSWKNRLRIATETAEALTYLHFAAS-----PPIYHRDVKSSNILLDEKLT--------------A
            . .|.|..|.|.|...||       |  |.|.| ..| .. |||         ||| ||| ||.|||.||..|              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVADFGISKLVP--IDSTHISTT----------------LHGTPGYIDPQY----------------QQSYQLTDKSDVYSFGVVILELITGQMPVDFSR
|..|||.|. .    ......||                  |||..  |                  ..... . |.||||||.|. |..|.. | .   
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

CASDK------NLSTFAMSVIQRGAISELIDKRLDARTPEMLE--CVAKVANLAALCLQFDGSSRPTMKFVLEEL
. . .           . .  .|  | .    ..  . . . .  |   ...|.  | . | ..||... .|..|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_ab.AA IRAK 15-215 33 3e-52 179.88 In-house 1-225 (317) Show / Hide 
Range on Protein: 15-215
Range on HMM: 1-225/317
Sequence Identity: 33% (76 aa)

FRSDLKLGTGSFGTVYKGKLDDGT-TVAIKKANNGNAPRI----QQFLN---EVTILSKVNHRNLVKMLGCCIEREVPLLVYEFVPRGTLYEHLHRRGD-
|  |...| | ||.||.|...  | ..|.||  ... . .    |.|.    |. ....  | |.|  .| |.||. . |||.. | |.|   |. ..  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-T---LSWKNRLRIATETAEALTYLHFAASP-PIYHRDVKSSNILLDEKLTAKVADFGISKL-----VPIDSTH---ISTTLHGTPGYIDPQYQQ--SYQ
 .   |||  |. |.  || .. .|| . .  || |.|.||.|||||. .|.| .|||         .  ..|    .  .. ||  |  | .    . |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTDKSDVYSFGVVILELITGQMPVD
|| |.||||||.|.||..||. .|.
LTKKTDVYSFGIVLLEVLTGCRAVY
Kinase IRAK-0_ab.AA Dicty4 15-213 33 1.8e-47 156.47 In-house 1-216 (277) Show / Hide 
Range on Protein: 15-213
Range on HMM: 1-216/277
Sequence Identity: 33% (74 aa)

FRSDLKLGTGSFGTVYKGKLDDGTTVAIKKA--NNGN--APRIQQFLNEVTILSKVNHRNLVKMLGCCI----EREVPLLVYEFVPRGTLYEHLHR----
   . ..|.||||.||||.   |. ||.||.  .| |  . ... |..||.|..|  | |... .| |.    . . .. | |..|.|.||. ||     
INIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--RGDTLSWKNRLR---IATETAEALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISKLVPIDSTHIS--TTLHGTPGYIDPQYQQSYQLTDKS
    ..|.|  ..|   .|  .|  ...|| .  | | ||| ||.|.| |. ...||.|||.|..   ...|    .|  |||..  |   ..   . |.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVVILELITGQMP
|||||| |  |. |.| |
DVYSFGIVLWEILTRQEP
Kinase IRAK-0_ab.AA TKL-Unique 20-213 31 9.3e-47 161.66 In-house 4-233 (290) Show / Hide 
Range on Protein: 20-213
Range on HMM: 4-233/290
Sequence Identity: 31% (73 aa)

KLGTGSFGTVYKGKLDDGTTVAIKKANN---GNAPRIQQFLNEVTILSKVN-HRNLVKMLGCCI----EREVPLLVYEFVPRGTLYEHLH---------R
|.|.|..|.|||||   |. ||||. ..    .   .| | |||....| . | |.|.  | |.          .| |..|.|.||..||         .
KIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

RGDTLSWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDEK-----LTAKVADFGISKLVPIDSTHIST--------TLHGTPGYIDPQYQQS-
.  .|....|...|   | .. |||.   | |.||| ||||.|.|..     . .|..|||.||.   ... ...        |  |.. .. |.   . 
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMN

-YQLTDKSDVYSFGVVILELITGQM------P
 .| . ||||||||.|  |..|..       |
FCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase IRAK-0_ab.AA S_TKc 15-293 24 1.4e-43 151.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-293
Range on HMM: 1-231/231
Sequence Identity: 24% (71 aa)

FRSDLKLGTGSFGTVYKGKLDD-GTTVAIKKANNGNAPRIQQFLNEVTILSKVNHRNLVKMLGCCIEREVPLLVYEFVPR--GTLYEHLHRRGD-----T
..   |.| |.||.|||..  . |  ||||. .       .....|. ||.| .| |.||..... . .   .| |...   |.|......||       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISKLVPIDSTHISTTLHGTPGYIDPQYQQSYQLTD-KSDVYSFGVVIL
..     ... ....|| |.|   |  | |||.| .||||||  . |..|||.....        ||. ||| |. |      . .  |.|..|.|... 
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELITGQMPVDFSRCASDKNLSTFAMSVIQRGAISELIDKRLDARTPEMLECVAKVANLAALCLQFDGSSRPTMKFVLE-ELKKAMQPLM
|...|. | .        .. .    .                           . ..   |||.| . |||   .|. |.. .. | .
EMLCGYPPFP--------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_ab.AA Pkinase 15-213 25 1.6e-41 147.9 Pfam 1-211 (293) Show / Hide 
Range on Protein: 15-213
Range on HMM: 1-211/293
Sequence Identity: 25% (55 aa)

FRSDLKLGTGSFGTVYKGKLDDGTT-VAIKKANNGNAPRIQQ--FLN--EVTILSKVNHRNLVKMLGCCIEREVPLLVYEFVPRG----TLYEHLH-RRG
..   |.| ||||.|||..  .    ||.|. .  ..   ..   ..  |. |. ..|| | |...... ..  . .| |... |     |..... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DTL--SWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDEKLTA----KVADFGISKLVPIDSTHISTTLHGTPGYIDPQYQQ-SYQLTDKSDV
 ..  |..   .........| |.|      | |||.|..|||.|.. .     |..|||..|.. . . .  ||. |||.|. |   . .   . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGVVILELITGQMP
.|.|... |...|. |
WSCGCILYEMLCGRPP
Kinase IRAK-0_ab.AA Pkinase_Tyr 15-163 27 2.1e-39 134.1 Pfam 1-161 (270) Show / Hide 
Range on Protein: 15-163
Range on HMM: 1-161/270
Sequence Identity: 27% (45 aa)

FRSDLKLGTGSFGTVYKGKLD-----DGTTVAIKKANNGNAPR---IQQFLNEVTILSKV-NHRNLVKMLGCCI-EREV--PLLVYEFVPRGTLYEHLHR
 . . ||| |.||.||||...     ....||.|. ..|  ..   .. |..|. |...  .| |.|...|.|. ..|   ...| |..| | |...|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---GDTLSWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISKLV
.   .. |. |  | .... |... ||.      . |||.   |.|..|....|..||| ....
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase IRAK-0_ab.AA LRRK 15-215 29 2.5e-39 136.81 In-house 1-284 (351) Show / Hide 
Range on Protein: 15-215
Range on HMM: 1-284/351
Sequence Identity: 29% (85 aa)

FRSDLKLGTGSFG-TVYKGKLDD---------------------------GTTVAIKKANNG---------------------------------NAPRI
...  ..| |.|| .||..|. .                           ...||||| | .                                 ...|.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-QQFLNEVTILSKVNHRNLVKMLGCCIEREVPL-LVYEFVPRGTLYEHLH-RRGDT-------LSWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSN
 . | .||.|.|. || |.|...| ||.   || .| |..| |.||..|| .. |        .||  .|.||.. |... |||  ..||| ||| || |
FREFRHEVWIMSHLNHPNIVSLKGFCIH---PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPN

ILL---D---------EKLTAKVADFGISKLVPIDSTHISTTLHGTPGYIDP---QYQ--QSYQLTDKSDVYSFGVVILELITGQ-MPVD
|||   .         .  .||.|||||| .  .. . .  .. |.||.  |   .|    .|  |.|.|.||||... ||.|.|  | |
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEY--TEKVDCYSFGMILWELLTRQHHPFD
Kinase IRAK-0_ab.AA Dicty4-Unclassified 15-213 35 5.7e-37 124.14 In-house 1-207 (263) Show / Hide 
Range on Protein: 15-213
Range on HMM: 1-207/263
Sequence Identity: 35% (76 aa)

FRSDLKLGTGSFGTVYKGKLDDGTTVAIKKANNGN-APR---IQQFLNEVTILSKVNHRNLVKMLGCCIER----EVPLLVYEFVPRGTLYEHLH----R
 . |  .| | |  |.||    |  ||.|| | .    |   || |. || ||  . | ||||. | ||           | || ..|.| |  |     
IQIDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

RGDTLSWKN--RLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISKLVPIDSTHISTTLHGTPGYIDPQYQQSYQLTDKSDVYSF
.   ..      ...| . |  . .||   .  . |||.||||||.|    .|.||||||    || .   ||  |||    |        . ||||||.
QQQPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRV--IDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSY

GVVILELITGQMP
...  ||.||  |
AMMLYELATGDEP
Kinase IRAK-0_ab.AA DRK 22-213 33 1.7e-36 121.13 In-house 8-201 (258) Show / Hide 
Range on Protein: 22-213
Range on HMM: 8-201/258
Sequence Identity: 33% (66 aa)

GTGSFGTVYKGKLDDGTTVAIKKANNGNAP---RIQQFLNEVTILSKVNHRNLVKMLGCCIEREVPLLVYEFVPRGTLYEHLHRRGDTLSWKNRLRIATE
| |..| |. |    || ||.|.. | |      .. |  |......  | | .  .| | .   .. . |. ||| ||  ||     ..|  .....  
GRGNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFD

TAEALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISK-LVPIDSTHISTTLHGTPGYIDPQYQQSYQLTDKSDVYSFGVVILELITGQMP
 |  ..|||    | | ||| || | | ||    |||||| |     . .     |  |||. . |    .   | | |||||..|  |..| | |
CAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDP
Kinase IRAK-0_ab.AA TK 15-213 16 4.8e-36 117.78 In-house 1-394 (486) Show / Hide 
Range on Protein: 15-213
Range on HMM: 1-394/486
Sequence Identity: 16% (67 aa)

FRSDLKLGTGSFG---TVYKGKLDDG--------------------------TTVAIKKANNGNAPRIQQ--------------FLNEVTILSKVN----
 .   ||| | ||   .||||.. ..                          |.||.|    |.|   ..              ||.|. .... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVKMLGCCIER------------EVPLLVYEFVPRGT----LYEHLHRRGDT--------------------------------------------
 | |.|...|.| .             | ...| |..| |     | ..|... ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWKNRLRIATETAEALTYLHFA----ASPPIYHRDVKSSNILLDEKLT-----------AKVADFGIS
                               |. . .| ..   |... |||        . . |||.   |.|..|...           .|.|||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

--------KLVPIDSTHISTTLHGTPG-------------------------YIDPQYQQSYQ---------LTDKSDVYSFGVVILELIT-GQMP
        . .. |.   ... .||..                         .  |   .. .          | ||||.||||.. |. | ||.|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase IRAK-0_ab.AA TyrKc 15-285 23 2e-35 124.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-285
Range on HMM: 1-280/280
Sequence Identity: 23% (73 aa)

FRSDLKLGTGSFGTVYKGKLDDGTTVAIKKANNGNAPRIQQFLNEVTILSKV--NHRNLVKMLGCCIER-------EVPLLVYEFVPRGTLYEHLHRRGD
 . . ||| | ||.||||...  ..||.|. ...    .. |..|  |..|.  .| |.|...|.|..        | ...| |..| | | ..|.....
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

TLSWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISKLVPID------STHISTTL--HGT---------PGYIDPQYQQS
.|..|  | ...  |.   |||     .. |||    |.|..|..|.|..||| |. .  |      .  ....   .|          |  |     . 
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NY

YQLTDKSDVYSFGVVILELITGQMPVDFSRCASDK-------NLSTFAMSVIQRGAISELIDKRLDARTPEM--LECVAKVANLAALCLQFDGSSRPTMK
.  | ||||.||||.. |.        |.....            . ..  ...|   .  .  .    | |   .| ... ..   | ..| ..|||..
GKFTTKSDVWSFGVCMWEI--------FTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFS

FVLEEL
 . |..
EIHECF
Kinase IRAK-0_ab.AA MLK 15-161 26 2.9e-33 112.79 In-house 1-181 (291) Show / Hide 
Range on Protein: 15-161
Range on HMM: 1-181/291
Sequence Identity: 26% (49 aa)

FRSDLKLGTGSFGTVYKGKLDDGT----TVAIKKAN---NGNAPR----IQQFLNEVTILSKVNHRN----LVKMLGCCIEREV-PLLVYEFVPRGTLYE
..   ..| |||| |.||.    .    .||.|...      . .    ...|  |. .|....|.|     .. .|.|.. .   ..| |... | ||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLHRRGD-------------TLSWKNRLRIATETAEALTYLHFAASPPIYHRDVKSSNILLDE------KLTAKVADFGISK
 || . .             . .    ...|.  |... |||  | .|| ||| ||.|||.||      ..|.|..|||.|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR
Kinase IRAK-0_ab.AA STE 15-213 24 3.1e-32 111.19 In-house 1-267 (359) Show / Hide 
Range on Protein: 15-213
Range on HMM: 1-267/359
Sequence Identity: 24% (68 aa)

FRSDLKLGTGSFGTVYKGKLDD----------------GTTVAIKKANNGNA-----------------PRIQQFLNEVTILSKVN--HRNLVKMLGCCI
..   |.| |.||||||..  .                |. .|||. |  |                    .||.|.|. |..| |  | | || .||..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-------EREVPLLVYEFVPRGTLYEHLH---RRGDTLS----------WKNRLRIATETAEA-LTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFG
       ...   .. |... |.| . ..    .|..|.           .   .|. .. .. | |||      | |||.|..||||     .| .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

ISK-LVPI-------------DSTH-ISTTLHGTPGYIDP-QYQQ-----SYQLTDKSDVYSFGVVILELITGQMP
... |...             ...   ..|. ||| .  |   ||     . . . |.|..|.| .|.|..||. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase IRAK-0_ab.AA Pkinase_Tyr 192-285 30 4.3e-07 24.63 Pfam 192-270 (270) Show / Hide 
Range on Protein: 192-285
Range on HMM: 192-270/270
Sequence Identity: 30% (29 aa)

TDKSDVYSFGVVILELIT-GQMPVDFSRCASDKNLST-FAMSVIQRGAISELIDKRLDARTPEMLECVAKVANLAALCLQFDGSSRPTMKFVLEEL
| ||||.||||.. |..| |..|             |   ||  .   . |.|...   | |    | ... .|  .| ..| . |||.. ..|.|
TTKSDVWSFGVLMWEIFTYGEQP-------------TYPGMSNEE---VYEYIYED-GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase IRAK-0_ab.AA MLK 186-213 37 1e-06 19.02 In-house 207-235 (291) Show / Hide 
Range on Protein: 186-213
Range on HMM: 207-235/291
Sequence Identity: 37% (11 aa)

Q-QSYQLTDKSDVYSFGVVILELITGQMP
| .. . . |.||.|.|||. |..|...|
QFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-0_ab.AA TK 256-285 19 0.002555 6.13 In-house 446-486 (486) Show / Hide 
Range on Protein: 256-285
Range on HMM: 446-486/486
Sequence Identity: 19% (8 aa)

CV-----------AKVANLAALCLQFDGSSRPTMKFVLEEL
..           . .. |   | ..| . |||.. ..|.|
WMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-0_ab.AA LRRK 266-287 27 0.012472 5.11 In-house 330-351 (351) Show / Hide 
Range on Protein: 266-287
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

LCLQFDGSSRPTMKFVLEELKK
.| | |  .||..  ... |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-0_ab.AA DRK 256-287 34 0.039582 3.05 In-house 227-258 (258) Show / Hide 
Range on Protein: 256-287
Range on HMM: 227-258/258
Sequence Identity: 34% (11 aa)

CVAKVANLAALCLQFDGSSRPTMKFVLEELKK
| .| . |   |.  | . ||.|  .|| |  
CPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase IRAK-0_ab.AA MLK 267-285 26 0.059409 2.72 In-house 273-291 (291) Show / Hide 
Range on Protein: 267-285
Range on HMM: 273-291/291
Sequence Identity: 26% (5 aa)

CLQFDGSSRPTMKFVLEEL
| . | ..||... ....|
CWNQDPHKRPSFRQIVQHL