View source for Kinase Family PRR1

__NOTOC__
[[kinase classification|Kinase Classification]]: [[Kinase_Group_CAMK|Group CAMK]]: [[Kinase_Family_PRR1|Family PRR1]]

PRR1 ([http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=PRR1 SGD]) is a yeast kinase that inhibits pheromone signaling, downstream of the MAPK kinases <cite>Burchett</cite>. Up until 2011, it was classified as CAMK-Unique, but then was placed in its own family, due to the presence of orthologs in other fungi including basidiomycetes such as [http://kinase.com/fungi/coprinopsis/ Coprinopsis cinerea]. The protein has multiple inserts within the kinase domain, of varying length in different orthologs, making blast-based homology comparisons difficult. It may be a member of the CAMKL family, but this needs more investigation. No clear homologs are found outside of fungi, but this has not been examined in depth.

====Evolution====


====Domain Structure====


====Functions====


==== References ====
<biblio>
#Burchett pmid=11337509
</biblio>