BCR_Mmus MVDSVGFAEAWRAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQ
BCR_Hsap MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQ
BCR_Spur MGG---------------------------------------------------------
RhoGAP1A_Dmel MSVFDDFQRLWMQRFPQSSLSDAW---EQDVRASLERHKVRINELSKELEQETLYVEYLE
ABR_Hsap MWDPRAFERRWRAEFPGAEAPVPRLESVRDAERELERRRLNLERLQQVLAEEQLKASLPQ
ABR_Mmus MWDPQEFERHWQAEFPGEETPVMKLESVPDMERELERCKLNLKRLQQVLAEEKFKVWYLQ
*
BCR_Mmus TLLAKEKKSYDRQRWGFRRAAQ---PPDGAAEPRASAPRPPPAPADGADPAPVEESEARP
BCR_Hsap TLLAKEKKSYDRQRWGFRRAAQ---APDGASEPRASASRPQPAPADGADPPPAEEPEARP
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel RLLSDVER----YRVSGGDPKALFEAASGSC---ASSNNSNC--SSTTNGATQEESNTNL
ABR_Hsap AALARG---------GGGDSG-----EPGRPDPEAESPRGDPGRPDPEAESPRG------
ABR_Mmus AALAGGKMELPGGRSEGGDGGG---CSSDTGSGGASVKEQEPAGPVRAPPPRDKEGAAGR
BCR_Mmus DGEGSPSKGRSASAR----------------RPAAAASADRD--DR--------------
BCR_Hsap DGEGSPGKARPGTAR----------------RPGAAASGERD--DR--------------
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel DKDFKSSLN-------------------LRESPSSTGAKDKDRLSLNPDNKYTTHTNAVI
ABR_Hsap ---------------------------DLPAGPGAAGEA---------------------
ABR_Mmus DPD-SPGPAHPGSEVATPAEPSPYVCLDLPAWPGAMEGG---------------------
BCR_Mmus ---------GPP-----------------------------------------TSVAALR
BCR_Hsap ---------GPP-----------------------------------------ASVAALR
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel GGIGSEKVSGPLHSTQITADGKRTGELYLKREEDKCKDSNSEDTDGALQQCITELAASLK
ABR_Hsap ---------G-----------------------------------------------GGR
ABR_Mmus ---------G-----------------------------------------------AVR
BCR_Mmus SNFEKIRKGPAQPGSADAEKPFYVNVEFHHERG-LVKVNDKEVSDRISSLGSQAMQMERK
BCR_Hsap SNFERIRKGHGQPG-ADAEKPFYVNVEFHHERG-LVKVNDKEVSDRISSLGSQAMQMERK
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel AQPDNVAGGRLEND-VDIDKPLRKSTSQYVTVIQVKEAKDKESADGTTSSSG-IGEPQQQ
ABR_Hsap SW-------------ADA-----VHRQLLQPQL-RFRAREDD------------------
ABR_Mmus SL-------------TAA-----IHQQLVQPRL-LFRLREDCAPPGNDGTGSTVPG-EER
BCR_Mmus KSQQSAGQGLGEAPRPHYR-GRSSESSCGLDGDYEDAELNPRFLKDNLINANG--GNR--
BCR_Hsap KSQHGAGSSVGDASRPPYR-GRSSESSCGVDGDYEDAELNPRFLKDNLIDANG--GSR--
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel PTPPSTFSRYSEATAPPLS-PSLTSYAAHVEAK---KKMPPRPPPKNIRRVEP--P----
ABR_Hsap -------APL---GDPQAAPGTDE-GGDGGDHDFEMVDFNEKFILSHWLVAPCRFGTRER
ABR_Mmus SSETGTGRGS-EEGEPDAS-GGDD-GGDCSDHDFEMVDLNEKFVLGHLLMAPCRFGTRDE
BCR_Mmus --PPWPPLEYQPYQSI--YVGGMM-----------VEGEG------------------KS
BCR_Hsap --PPWPPLEYQPYQSI--YVGGMM------------EGEG------------------KG
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel -TIPSQQLSSSPKRETYM--INTM------------PSSSSGSLCIDSLGNSLERNIKPS
ABR_Hsap A--------RSPRRWMHLIPGGRR-PQRGTRDLEQREAEAKG--------------RPGS
ABR_Mmus AEKPARP--CSPHRWMHLISGGWRHHRRRSRDLEQLEAEDE------------------S
BCR_Mmus PLLRSQSTSEQEKRLTWPRRSYSPRSFEDSGGGYTPDCSSNENLTSS--EEDFSSGQSSR
BCR_Hsap PLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSS--EEDFSSGQSSR
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel DILRQKSSDNLDSKYSAKRKT-------------TPELSKFVNVNN--PELMEELGR-KM
ABR_Hsap PL-AAEETPGREHLPPWRRRRFLRVPERDSPGHSSPERDSDGSRHSSDREDDFS------
ABR_Mmus PR-----RGAREHLAQWGRKRFLRVPDRDSPSHSSPERGSDCSHNSSDHEDGFS------
BCR_Mmus VSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCQKRHRQCQVVVSEATIVGVRKTGQ
BCR_Hsap VSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQ
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel VSKADSL-EQTRRNDSSPSGCGSLGRTSSTPGRSLTPGR-----TGVGASPTGSLSKTGK
ABR_Hsap ------------------------------------------------------------
ABR_Mmus ------------------------------------------------------------
BCR_Mmus IWPSDG--------DSTFQGEADSSFGTPPGYGCAADQAEEQRRH---------------
BCR_Hsap IWPNDG--------EGAFHGDADGSFGTPPGYGCAADRAEEQRRH---------------
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel LAMADSSSTSSLERRSCLQ-AVDADIGTESRESGANQRSVGSKESLTSQGISEVIKSYES
ABR_Hsap ---------------------ADFSYGTDEYDGEGNEEQKGPPEG---------------
ABR_Mmus ---------------------ADFSYGAEDYDAEGHEEQKGPPEG---------------
BCR_Mmus ------------------------QDGLPYIDDSP-------------------------
BCR_Hsap ------------------------QDGLPYIDDSP-------------------------
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel VSSLSSESAKAVASQQSAAAGGALAECEPYYDSVPLDNGDGEYVFIKPGRTGSSSSRDDL
ABR_Hsap ------------------------SETMPYIDESP-------------------------
ABR_Mmus ------------------------SETMPYIDESP-------------------------
BCR_Mmus ---------------SSSPHLSSKGRGSLAS---GALDPTKVSEL---------------
BCR_Hsap ---------------SSSPHLSSKGRGSRDALVSGALESTKASEL---------------
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel STPGSSILPLPNVADPESPGRTSNY-VNIDFFLQQGI-ETRSSSLDSDGEYEGPPILRTI
ABR_Hsap ---------------TMSPQLSARSQGGGDGV-SPTPPEGLAPGV---------------
ABR_Mmus ---------------TMSPQLSARSQGGGDSV-SPTPPEGLAPGV---------------
BCR_Mmus --------------------------DLEKGLEMRKWVLSGILASEETYLSHLEALLLPM
BCR_Hsap --------------------------DLEKGLEMRKWVLSGILASEETYLSHLEALLLPM
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel SHDDQTTTQTTPGAIRKNLVSAILVCGNARGAKIRS-ILSSIIQSETIYVECLNKMMQYK
ABR_Hsap --------------------------EAGKGLEMRKLVLSGFLASEEIYINQLEALLLPM
ABR_Mmus --------------------------EAGKGLEMRKLVLSGFLASEEIYINQLEALLLPM
BCR_Mmus KPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKL
BCR_Hsap KPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKL
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel KAIHATLTTSQPVIREEEENTIFFKIDELYDLHTGFLSDLKTIVSHEGGDVLIGEPFRRL
ABR_Hsap KPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKL
ABR_Mmus KPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKL
BCR_Mmus ASQLGVYRAFVDNYGVAMETAEKCCQANAQFAEISENLRARSNKDVKDSTTKNSLETLLY
BCR_Hsap ASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLY
BCR_Spur ------------------------------------------------------------
RhoGAP1A_Dmel AEMFDLYSAFLHNYKNAIETVKKCSANNPQFKKIVSTIVLNL-----QTEQSLTLEDLLH
ABR_Hsap ASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLY
ABR_Mmus ASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLY
BCR_Mmus KPVDRVTRSTLVLHDLLKHTPSSHPDHSLLQDALRISQNFLSSINEEITPRRQSMTVKKG
BCR_Hsap KPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKG
BCR_Spur -----------LKSDLLKHTPEHHEDHSILSQVLEKTRKFFKQVDEAT--R-E-IHST-K
RhoGAP1A_Dmel KPVARVQINALVFNDLLRETPNAHPDHQPLRQAQKIIQMFLNQFNV--VNQRLPIESN-R
ABR_Hsap KPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKG
ABR_Mmus KPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKG
: ***:.** * *: * :. . : *:...: : :
BCR_Mmus EHRQLLKDSFMVELVEGARKLRHIFLFTDLLLCTKLKKQSG---GKTQQYDCKWYIPLTD
BCR_Hsap EHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSG---GKTQQYDCKWYIPLTD
BCR_Spur QKRELLRQGYLVEWTEGGRKLRRVLLWSDLIICASKKNTSGMFQRDRGQYDFQWYIPLTE
RhoGAP1A_Dmel NLRRMVRNSFIVELVDGHRKLRHLFLFNDVIACAKYKAL-G---RDRIDYELKWFIPLKD
ABR_Hsap ETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSA---GKHQQYDCKWYIPLAD
ABR_Mmus ETRQLVKDGFLVEMSESSRKLRHVFLFTDVLLCAKLKKTSA---GKHQQYDCKWYIPLAD
: *.::::.::** :. ****:::*:.*:: *:. * . . :*: :*:*** :
BCR_Mmus LSFQMVDELEALPNIPLVPDEELDALKIKISQIKSDIQREKRANKG----SKVMERLRKK
BCR_Hsap LSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKG----SKATERLKKK
BCR_Spur LSLTPNDRCEAEPDVVAKSDAELRQMKKDISELQEKIKRDK-AAKQSNAIKKSIEQKRKQ
RhoGAP1A_Dmel VSIY--EEADPAVELKESSPANISQVKRNLRSVRDQLAMEV-ANSG-SGAFRSGDKYRRK
ABR_Hsap LVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEK-ANKGQ---SRAIERLKKK
ABR_Mmus LVFPSPEESEASPQVHPFPDHELEDMKTKISALKSEIQKEK-ANKGQ---SRAIERLKKK
: : :. :. :: . :: :* .: ::..: : * . : :: :::
BCR_Mmus LSEQESLLLLMSPSMAFRVHSR-NGKSYTFLISSDYERAEWRESIREQQKKCFK--SFSL
BCR_Hsap LSEQESLLLLMSPSMAFRVHSR-NGKSYTFLISSDYERAEWRENIREQQKKCFR--SFSL
BCR_Spur AAELEVGYVLESPNLPFHLYHH-SGKTYTILMSSDYERSDWKDSILSAKRECRI--TPSI
RhoGAP1A_Dmel LADLESQLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWIDSILSLKQKCNLPGANTI
ABR_Hsap MFENEFLLLLNSPTIPFRIHNR-NGKSYLFLLSSDYERSEWREAIQKLQKKDLQ--AFVL
ABR_Mmus MFENEFLLLLNSPTIPFRIHNR-NGKSYLFLLSSDYERSEWREAIQKLQKKDLQ--AFVL
: * :* :*.: ::: : ..*: :::***:**::* : * . ::: : :
BCR_Mmus TSVELQMLTNSCVKLQ-TVHHIPLTINKEDDESPGLYGFLHVIVHSATGFKQSSNLYCTL
BCR_Hsap TSVELQMLTNSCVKLQ-TVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTL
BCR_Spur TPYHVSKLIPKTRRGRDSYVNISSVLLKDNDEL--LTGMLHVTVKEARGLTVPSQLYCCL
RhoGAP1A_Dmel NSLEVTAFIVAMQKGMKTEMG-SYLMRNTNDES-LLVGDLYMGVHGLEGLEQANDLYICV
ABR_Hsap SSVELQVLTGSCFKLR-TVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL
ABR_Mmus SSVELQVLTGSCFKLR-TVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL
.. .: : : : . : :** * * * : *: *: . :** :
BCR_Mmus EVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRILCYEKCYNKMKMTKEDGES
BCR_Hsap EVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGES
BCR_Spur ETDAYGIFSRMAKTRKTANTITPKWNEEFALDVDGARTLRILCYDFTKG----------L
RhoGAP1A_Dmel EVDSYGHYFRKATTKKICRSQTPLWNESFMLELEGSQNVRILLYEAKE------------
ABR_Hsap EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI
ABR_Mmus EVDSFGYFVSKAKTRVFRDTTEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI
*.*::* : *.*: : * *:*.* ::::*::.:*** *:
BCR_Mmus ADKLMGKGQVQLDPQTLQDRDWQRTVIDM-------------------------------
BCR_Hsap TDRLMGKGQVQLDPQALQDRDWQRTVIAM-------------------------------
BCR_Spur DDEMYDKGAVSLTKQNISSPGGMDCTIQMDQCSDFLKMWRFCLVVYAYARNNLFGCIGIP
RhoGAP1A_Dmel RPLLKAKHILKLSLSWLTETTQPKSIKLT-------------------------------
ABR_Hsap VDKIMGKGQIQLDPQTVETKNWHTDVIEM-------------------------------
ABR_Mmus VDKIMGKGQIQLDPQTVESKNWHTDVIEM-------------------------------
: * :.* . :
BCR_Mmus --------NGIEVKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQC
BCR_Hsap --------NGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQC
BCR_Spur SVKLKTQDDSLQVDVTVRFETSERTLKRVQSRKKMGVFGVHVGTLAHRQGKNIPNIITLC
RhoGAP1A_Dmel --------ETLELGCSFRFIPGEL--FR-GSTKPGALFGAKMSQVLKREKRDIPFIIGAC
ABR_Hsap --------NGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQC
ABR_Mmus --------NGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQC
: ::: :.:* . : * * * .:**.::. : :*: .:* *: *
BCR_Mmus VEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRE
BCR_Hsap VEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRE
BCR_Spur VEEIDRRGVHEMGIYRISGSSADIQKLKKAFEQNRRNITAMLKQSDIHAVAGLLKSYLRE
RhoGAP1A_Dmel IREVERRGMLEVGCYRVSGSASDLAKLKKAFESDAYEAEQLLREVDIHSVTGILKTFLRE
ABR_Hsap VEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRE
ABR_Mmus IEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRE
:.*:::**: *:* **:** ::*: ** .*: : : :: : *:::::* ** ::**
BCR_Mmus LPEPLFTDEFYPNFAEGIAL---SDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAE
BCR_Hsap LPEPLFTDEFYPNFAEGIAL---SDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAE
BCR_Spur LPEPLFTHVLYPQFVDGLQL---TDPVAKKKCFLSLLKNVVEPNRTIIFLIFNHLRRIAK
RhoGAP1A_Dmel LPEALFTDQLYPRFFDTFSAFSNNNESTRINELLKVFEELPQANKASITSILDHLIRVHE
ABR_Hsap LPEPLLTDRLYPAFMEGIAL---SDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAE
ABR_Mmus LPEPLLTDRLYPAFMEGIAL---SDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAE
***.*:*. :** * : : .: :: . :: :: .: :.* : :::** *: :
BCR_Mmus KETVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSW-SLEVMSQVQVLLYFL
BCR_Hsap KEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSW-SLEVMSQVQVLLYFL
BCR_Spur EEEKNKMNLHNLSTVFGPTLLGPAATISATG----KPDILAEIMGMSSVISQVGILHYCL
RhoGAP1A_Dmel KETDNKMSLHNLAMVFGPTLLRPGQTQVKQKD-----PLAA---STVDVMAQAGILYCFL
ABR_Hsap KEPINKMSLHNLATVFGPTLLRPSEVESKAHL-----TSAADIW-SHDVMAQVQVLLYYL
ABR_Mmus KEPINKMSLHNLATVFGPTLLRPSEVESKAHL-----TSAADIW-SHDVMAQVQVLLYYL
:* ***.****: ******* *. : .*::*. :* *
BCR_Mmus QLEAIPAPDSKRQSILFSTEV
BCR_Hsap QLEAIPAPDSKRQSILFSTEV
BCR_Spur EHFSESV-------EILETDL
RhoGAP1A_Dmel QARI--------------KKD
ABR_Hsap QHPPISFAELKRNTLYFSTDV
ABR_Mmus QHPPISFAELKRNTLYFSTDV
: ..