LMR3_Hsap MPAPGA-----LILLAAVSASG--------------------------------------
LMR2_Hsap MPGPPALRRRLLLLLLVLLIAG-S------------------------------------
LMR1_Hsap MS-------------------S-SFFNPS--------------------------F----
LMR3_Mmus MPAPGA-----LILLAAVSASG--------------------------------------
LMR2_Mmus MPGPPASPPPPMLLLLLLLTVG-C------------------------------------
LMR1_Mmus ML----------IALLALAMSS-SFFNPS--------------------------F----
LMR_Spur MARLTFST-GTCALLVCAFISG--------------------------------------
AqueK333_Aque MNTNVS-----IGLLI-LSIACLSLGQPICQAPQNTLYSNTDLNVFSNCQQINGSLVMGD
*
LMR3_Hsap ------------------------------------------------------------
LMR2_Hsap ------------------------------------------------------------
LMR1_Hsap ------------------------------------------------------------
LMR3_Mmus ------------------------------------------------------------
LMR2_Mmus ------------------------------------------------------------
LMR1_Mmus ------------------------------------------------------------
LMR_Spur ------------------------------------------------------------
AqueK333_Aque QFCTRSCTITDFSALSNLQAITGSFIVQCCHTLSVFPNIPRLTQIQGALRIYYNTGLRSI
LMR3_Hsap ------------------------------------------------------------
LMR2_Hsap ------------------------------------------------------------
LMR1_Hsap ------------------------------------------------------------
LMR3_Mmus ------------------------------------------------------------
LMR2_Mmus ------------------------------------------------------------
LMR1_Mmus ------------------------------------------------------------
LMR_Spur ------------------------------------------------------------
AqueK333_Aque AGLILGTVGSLEIAQNQLLHSIDVLQINRISNYVSISYNPSLGSIRGLTNLISIEGNQLV
LMR3_Hsap ------------------------------------------------------------
LMR2_Hsap ------------------------------------------------------------
LMR1_Hsap ------------------------------------------------------------
LMR3_Mmus ------------------------------------------------------------
LMR2_Mmus ------------------------------------------------------------
LMR1_Mmus ------------------------------------------------------------
LMR_Spur ------------------------------------------------------------
AqueK333_Aque NGHALRILYNPILTDISGFQSLDTINYGTVHIEGNTQLCYSGYPRWSYGSYESRYSTGDK
LMR3_Hsap ---------------------------------------------------CLA------
LMR2_Hsap ---------------------------------------------------AGA------
LMR1_Hsap ---------------------------------------------------AFS------
LMR3_Mmus ---------------------------------------------------CLA------
LMR2_Mmus ---------------------------------------------------ARA------
LMR1_Mmus ---------------------------------------------------AFS------
LMR_Spur ---------------------------------------------------SLA------
AqueK333_Aque GIDWRSKLNTQYSWQFTWGGNGVPTLNIQGNGNYSTCASTTCHSSCQSGVGCLGPSNPGL
. .
LMR3_Hsap -----------------SPAH--PDG---FALGRAPLA-PPYAVVLISCSGLLAFIFLLL
LMR2_Hsap -----------------APLP--QTG---AGE-APPAAEVSSSFVILCVCSLIILIVLIA
LMR1_Hsap -----------------SHFD--PDG---APLSELSWP-SSLAVVAVSFSGLFAVIVLML
LMR3_Mmus -----------------SPAH--PDG---FALSRAPLA-PPYAVVLISCSGLLAFIFLLL
LMR2_Mmus -----------------APLP--QTG---AGE-VP-VVEVPSLFVILSVCSLLILIVLIA
LMR1_Mmus -----------------SHFD--PDG---APLSELSWS-SSLAVVAVSFSGIFTVVILML
LMR_Spur -----------------APLT----G---SE-DQEPFS--LLVSVSLSLASLLILVLAVV
AqueK333_Aque CGSCYQTSTINSCDEVSAPETVTQNCVTLWPPTELPFS--AIFGLLVACGGTLIIIVLIA
: : :. . : .:. :
LMR3_Hsap TCL-CCKRGDVGFKEFENPEGE----------DCSGEYTPPAEETSSSQ-----------
LMR2_Hsap NCVSCCKDPEIDFKEFEDNFDD----------E--IDFTPPAEDTPSVQ-----------
LMR1_Hsap ACL-CCKKGGIGFKEFENAEGD----------EYAADLAQ-GSPATAAQ-----------
LMR3_Mmus TCL-CCKRGDVRFKEFENPEGE----------DCSGEYTPPAEETSSSQ-----------
LMR2_Mmus NCVSCCKDPEIDFKEFEDNFDD----------E--IDFTPPAEDTPSIQ-----------
LMR1_Mmus ACL-CCKKGGIGFKEFENAEGD----------EYVADFSEQGSPAAAAQ-----------
LMR_Spur GCA-CCFGKSSLLKYEESVEYEERNPNQSHTNDGFADFSPPTQSTPSFPPGGV-------
AqueK333_Aque LCI-VVYKIRKKCNGDEESKG-NYNVNE-RNLESGS-SYQPSRNTYSSGSRSKLHHSNNE
* : *. : : :
LMR3_Hsap --------------SLPDVYILPLAEVSLPMPAP---------------QPSH-------
LMR2_Hsap --------------SPAEVFTLSVPNISLPAPS----------------QFQP-------
LMR1_Hsap --------------NGPDVYVLPLTEVSLPMAK----------------QPGR-------
LMR3_Mmus --------------SLPDVYILPLAEVSLPMPAP---------------QPPH-------
LMR2_Mmus --------------SPAEVFTLSVPNISLPAPS----------------QFQA-------
LMR1_Mmus --------------TGPDVYVLPLTEVSLPMAK----------------QPGR-------
LMR_Spur ------SETVSIE-ALPDLSSRLQTSHGLPQVS----------------TALSSDVG---
AqueK333_Aque MEMRETSPQVSSYNPADDDYTYSQVVKKTPTAQETRKQEEPIVHKPTYEERQKEKEESEE
: *
LMR3_Hsap ------------S-D-MTT-PLGLSRQHLSYLQEIGSGWFGKVILGEI---FSDYTPAQV
LMR2_Hsap ------------SVE-GLK-S-QVARHSLNYIQEIGNGWFGKVLLGEI---YTGTSVARV
LMR1_Hsap ------------SVQ-LLK-STDVGRHSLLYLKEIGRGWFGKVFLGEV---NSGISSAQV
LMR3_Mmus ------------S-D-IST-PLGLSRQHLSYLQEIGSGWFGKVILGEV---FSDYSPAQV
LMR2_Mmus ------------SVE-GLK-S-QVARHSLNYIQEIGSGWFGKVLLGET---YTGTSVARV
LMR1_Mmus ------------SVQ-LLK-STDLGRHSLLYLKEIGHGWFGKVFLGEV---HSGVSGTQV
LMR_Spur --------NQDGELKHLKSPRFVFPRDQLNYVDELGNGWFGKVLQGEAHRLHPGMRKTRV
AqueK333_Aque EEEEEEESEEEPRDN-FME-EYEMPSRKIQLMKEIGEGSFGKVFKGLASDVLPNERVTDV
. . : :.*:* * ****: * .. : *
LMR3_Hsap VVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRY
LMR2_Hsap IVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAY
LMR1_Hsap VVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGY
LMR3_Mmus VVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRY
LMR2_Mmus IVKELKVSASPKEQDTFLKSGEPYYILQHPNVLQCVGQCVEAIPYLLVFEFCDLGDLKAY
LMR1_Mmus VVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGY
LMR_Spur VIKQLRDTSTPDEQLLFLQEVQPYREVNHPNVLMLLGQCIESIPLLLVLEYAPYGDLKNY
AqueK333_Aque IVKQSHRNATEDELEDFLEPAEKMRNLKHDNVLHLLGVCVDSDNMLIVLEDCANGNFKTF
::*: : .: * *:. : ::* *:* :. * : *:::* . *::* :
LMR3_Hsap LRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVR
LMR2_Hsap LRSEQEHMRGDS-----QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVK
LMR1_Hsap LRSCRVAESMAP-----DPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVK
LMR3_Mmus LRAQRPPEGMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVR
LMR2_Mmus LHNEQEHVRGDS-----QTMLLQRMACEIAAGLAAMHKLHFLHSDLALRNCYLTSDLNVK
LMR1_Mmus LRSCRVTESMAP-----DPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVK
LMR_Spur LRKNRGMVAQMA-----QKDVQLRMAHDIISGLLWLHQADFIHIDFAARNCQVCADASVK
AqueK333_Aque LINKRSHMEMMK-----KDGSLLQMIIEMAEGLNYLHENSITHSDFAARNCLVCANNRIK
* : . :* :: *: :* * *:* *** : :: ::
LMR3_Hsap IGDYGLAHSNYKEDYYL-TPER-LWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVT
LMR2_Hsap VGDYGIGFSRYKEDYIE-TDDK-KVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVT
LMR1_Hsap IGDYGLAHCKYREDYFV-TADQ-LWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVT
LMR3_Mmus IGDYGLAHSNYKEDYYL-TPER-LWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVT
LMR2_Mmus VGDYGIGFSRYKEDYIE-TDDK-KVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVT
LMR1_Mmus VGDYGLSHCKYREDYLV-TADQ-LWVPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVT
LMR_Spur IGDYGLALEQYPEDYYI-TKDECHAVPIRWLGPEVMEIRGQDIKPKKITKKSNIWSFGVI
AqueK333_Aque VGDYGLSRQLFRGDYYSRTPGQ-TAWPIRWMAPEVFIEVKGMIKSTKETTASNIWSFGIT
:****:. : ** * . *:** .**:. : . : .*:**:*:
LMR3_Hsap LWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRP
LMR2_Hsap LWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLSPEKRP
LMR1_Hsap IWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRP
LMR3_Mmus LWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRP
LMR2_Mmus LWELFNNAAQPYANLSDLDVLNQVIRERDMKLPKPQLEQPYSDRWYEVLQFCWLPPDKRP
LMR1_Mmus IWELFELGAQPYPQHSDGQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCWLQPEQRP
LMR_Spur MLELSTAADRPYPDLSDEQVLKQVVMDQDIKLDKPNLDLKYAERWFEIMMFCWMDSDTRP
AqueK333_Aque LWEVSTFAEQPYPDMTDEEVIEQVARREYCNLRNPVPTFDPLCALFAIMMKCWKRERERP
: *: . :** . :: :*: . . :* .* : :: ** **
LMR3_Hsap SASDLQLQLTYLLSERPP-R----------PPPPPPPPRDGPFPWPWPPAHSAPRPGTLS
LMR2_Hsap AAEDVHRLLTYLRLQSQR-DSEVDFEQQWNALKP----------------NTNSRDSSNN
LMR1_Hsap TAEEVHLLLSYLCAKGAT-EAEEEFERRWRSLRPGGGG-VGPGPGAAGPMLGGVVELAAA
LMR3_Mmus SASDLQLQLTYLLSERPP-R----------PPPPPPPPRDGPFPWPWPPSHSAPRPGTLS
LMR2_Mmus AAEDVHRLLTYLRMQSQR-DSEVDFEQQWTALKP----------------DTNSRDASSS
LMR1_Mmus TAEEVHLLLSYLCAKGTT-ELEEEFERRWRSLRPGGSTGLGSGSAAPAAATAASAELTAA
LMR_Spur TVKEVHELLTHLKNNIER-FHMEDFETKWNALKP----------------AMANQSSSEC
AqueK333_Aque NMASVLTLLKNVTLNTRGMEAKESIRLKAAA----------------KTKRKSGRPQRES
.: *. : : .
LMR3_Hsap SPFPLLDG-FP----GADPDDVLTVTESSRGLNLECLWEKA--RRGA--GRGGG------
LMR2_Hsap AAFPILDH-FARDRLGREMEEVLTVTETSQGLSFEYVWEAA--KHDHFDERSRGHLDEGL
LMR1_Hsap SSFPLLEQ-FAGDGFHADGDDVLTVTETSRGLNFEYKWEAG--R---------G------
LMR3_Mmus SQFPLLDG-FP----GADPDDVLTVTESSRGLNLECLWEKA--RRGA--GRGGG------
LMR2_Mmus AAFPILDH-FARDRLGREMEEVLTVTETSQGLSFEYVWEAA--KHDHFDEQGRGHPDEAL
LMR1_Mmus SSFPLLER-FTSDGFHVDSDDVLTVTETSHGLNFEYKWEAG--C---------G------
LMR_Spur -------------------------SETSQE-----------------------------
AqueK333_Aque SQEPLLATSLTMESDGGES---------EEGRSRKSAREEKKGKEEKRDER-RGEENRKL
..
LMR3_Hsap --------APAWQPAS--APPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLE
LMR2_Hsap SYTSIFYPVEVFESSL--SDPGPGKQDDSGQDVPLRVPGVVPVFDAHNLSVGSDYYIQLE
LMR1_Hsap --------AEAFPAT---LSPGRTARLQELCAPDGAPPGVVPVLSAHSPSLGSEYFIRLE
LMR3_Mmus --------APPWQPAS--APPAPHTNPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLE
LMR2_Mmus SYSSMFFPVEVFENSL--SDPGPGKQDDSGQEVPVRAPGVVPVFDAHNLSVGSDYYIQLE
LMR1_Mmus --------AEEYPPSGAASSPGSAARLQELCAPDSSPPGVVPVLSAHSPSVGSEYFIRLE
LMR_Spur ---------------------------TPQQEI---------------------------
AqueK333_Aque KETKITVEAEVREE-----------------------------------------VVQAE
LMR3_Hsap EHGSP------------PEPL--FPNDWDPLDPGVP------------------------
LMR2_Hsap EKSGSNLELD------YPPAL--LTTDMDNPE--RTGPELSQLTALRSVELEESSTDEDF
LMR1_Hsap EAAPA-AGHDPDCAGCAPSPP--ATADQDDDSDGSTAASLAMEPLLG----HGPPVDVPW
LMR3_Mmus EHGSP------------PEPL--FPNDWDPLDPGVP------------------------
LMR2_Mmus EKSSSNLGL-------DPPAL--LTTEVDKLE--RAGAEEPR-------------TEEDF
LMR1_Mmus GAVPA-AGHDPDCAGCAPSPQ--AVTDQDNNSEESTVASLAMEPLLG----HAPPTEGLW
LMR_Spur -SLE-IGGGDPLSIGVAKGDPLSVVSDMSQNQTQQVVSVDV-------------------
AqueK333_Aque EK----------------------------------------------------------
LMR3_Hsap -----------------------APQA-PQ-A---PSEVPQLVSETWASPLFPAPRPFPA
LMR2_Hsap FQSSTDPKDSSLPG---DLHVTSGPES-PFNN---IFNDVD-------------------
LMR1_Hsap GRGDHYPRRSLARDPLCPSRSP-SPSAGPLSLAEGGAEDADWGVAAFCPAFFEDP--LGT
LMR3_Mmus -----------------------GPQA-PQ-T---PSEVPQLVSETWASPLFPAPRPFPA
LMR2_Mmus FQSSAHPKEASSTE---DSRATSIPGS-PF-N---LFSDLD-------------------
LMR1_Mmus GPCDHHSHRRQ--GSPCPSRSP-SPGT-PM-L---PAEDIDWGVATFCPPFFDDP--LGA
LMR_Spur ------------------------------------------------------------
AqueK333_Aque ------------------------------------------------------------
LMR3_Hsap QSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSL
LMR2_Hsap --------------KSEDLPSHQKIFDLMELNGVQADF-------------KPATLSSSL
LMR1_Hsap SPLGSSGAPPLP---------------------------LTGEDELEEVGAR--------
LMR3_Mmus QSSGSGGFLLSGWDPEGRGAGETLAGDPAEVLGEQGTAPWAEEE---EEESSPGEDSSSL
LMR2_Mmus --------------KADDLPSHQKIFDLMELNGVQADF-------------KPAILSSSL
LMR1_Mmus SPSGSPGAQPSP---------------------------SDEEPEEGKVGL---------
LMR_Spur ------------------------------------TGPSLGQTDHE---DQLFDDLSKK
AqueK333_Aque -------------------------------------------------SKKSGKRDSKG
LMR3_Hsap G-------------GGPSRRGPLPCPLCSREGA---------------CSCLPLERGDAV
LMR2_Hsap DNPKESVITGHFEKEKP-RKIFDSEPLCLSDNLMHQDNFDPLNVQELSENFLFLQEKNLL
LMR1_Hsap ---------------RAAQRGHWRSNVSANNNS---------------GSRCP-ESWDPV
LMR3_Mmus G-------------GGPSRRGPLPCPLCSREGP---------------CSCLPLERGDAV
LMR2_Mmus DDPKDTC---QSDKEKP-HKLLDQGPLCLSESLLHQDHFDPLSVQELSENFLFLQEKNLL
LMR1_Mmus ----------------AAQCGHWSSNMSANNNS---------------ASRDP-ESWDPG
LMR_Spur G-------------QGQEKNQPFEISFD--------------------------------
AqueK333_Aque G-------------KEKSKKGSKKKETESKK----------------------KVTGDPV
:
LMR3_Hsap AG---WGGHPALGCPHPPEDDSSLRAER------GSLADLPMAPPAS-------APPEFL
LMR2_Hsap KG-----------SLSSKEHINDLQTELKNAGFTEAMLETSCRNSLD-------TELQFA
LMR1_Hsap SA----GGH-AEGCPSPK--------------------QTPRASPEPG------YPGEPL
LMR3_Mmus AG---WGDHPALGCPHPPEDDSSLRAER------GSLADLPLVPPTS-------APLEFL
LMR2_Mmus KG-----------SLTTKEQVSDLQTELKNAGFTSALLESPQRGSES-------SELEFL
LMR1_Mmus YVSSFTDSY-RDDCSSLE--------------------QTPRASPEVGHLLSQEDPRDFL
LMR_Spur -------------------------------------------EPEQE------AP----
AqueK333_Aque ----------PTSVPVVPHKDE-----H------SDI--------------------SDM
LMR3_Hsap DPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDS
LMR2_Hsap ENKPGLSLLQEN--------------------------------------------VSTK
LMR1_Hsap LGLQA-ASAQEPGCCPG-LPHLCSAQGLAPA---PCLVTPSWTETASSGGDHPQAEPK-L
LMR3_Mmus DPLMGAAAPQYPGRGPPPAPPPPPPPPRASAEPAASPDPPSALASPGSGLSSPGPKPGDS
LMR2_Mmus ENTLDFPLSQGD----------------------------------------------TR
LMR1_Mmus PGLVAVSPGQEPSRPFN-LLPLCPAKGLAPA---ACLITSPWTEGAVGGAENPIVEPK-L
LMR_Spur ---------------------TNMPETETVSEIIPSVATPQANMAPPAGGDSTHELSFED
AqueK333_Aque DD------IFYP-SGPPPAP-------------------AAAHASPPSD-----------
LMR3_Hsap GYETETPFSPEGAFPGGGA--AEEEGVPRPRAPPE--PPDPGAP-RPPPDPGPLPLPGPR
LMR2_Hsap GDDTDVML------TGDTLSTSL-QSSPEVQVPPTSFETEETPR-RVPPD--SLPTQGET
LMR1_Hsap ATEAEGTTGPRLPLPSVPS--PSQEGAPLPSEEAS--APD--AP-DALPDS-PTPATG--
LMR3_Mmus GYETETPFSPEGAFPGGGA--AEEEGVPRPRAPPE--PPDPGAP-RPPPDPGPLPLPGSQ
LMR2_Mmus GQN-----------EGAGV--RR-HSGTSPQASPAL-LTEEGSP-TAPTD--PILKPEET
LMR1_Mmus AQEAEGSAEPQLPLPSVPS--PSCEGASLPSEEAS--APD------ILPAS-PTPAAG--
LMR_Spur AFDTPTPQGDRKTD-TLSF--GLDDSVPSAEVTPN--TPDFFSSEDVNPVEASTPFPSSQ
AqueK333_Aque ---------------------DEESWDERVIPPPH--PPSQLPS-QP-----------QS
. ..
LMR3_Hsap EKPTFVVQVSTEQLLMS-------------------------------------------
LMR2_Hsap QPTCLDVIVPEDCLHQDISPDAVTVPVEILSTDARTHSLDNRSQDSPGESEETLRLTESD
LMR1_Hsap ------GEVSAIKLASA-------------------LNGSSSS-----------------
LMR3_Mmus EKPTFVVQVSTEQLLMS-------------------------------------------
LMR2_Mmus -KSFRDVRVPEDSICLELGPDPVTVGVEIPATDAKTLDGGNRPPDVTCQSKEALSLTNRH
LMR1_Mmus ------SWVTVPEPAPT-------------------LESSGSS-----------------
LMR_Spur Q-PNMQVSIDTS---------VSAG-----------------------------------
AqueK333_Aque ------------------------------------------------------------
LMR3_Hsap -------------------------------LREDV------------------------
LMR2_Hsap SVLADDILASRVSVGSSLPELGQELHNKPFSEDHHSHRRLEKNLEAVETLNQLNSKDAAK
LMR1_Hsap ------------------PE-----VEAPSSEDEDT------------------------
LMR3_Mmus -------------------------------LREDV------------------------
LMR2_Mmus PILVNDITAQ-GSVESCLPESRQDLQNEPFSEDPLSVSSLEKHSEAAETLNQLNSKAAPE
LMR1_Mmus ------------------LG-----QEAPSSEDEDT------------------------
LMR_Spur ------------------------------------------------------------
AqueK333_Aque ------------------------------------------------------------
LMR3_Hsap -TRNLLG---EKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLP----
LMR2_Hsap EAGLVSALSSDSTS--QDSLLEDSLSAP-FP-------ASEPSLETPDSLESVDVHEALL
LMR1_Hsap -AEATSGIFTDTSS--DGLQARRPDVVPAFR-------SLQKQVGTPDSLDSLDIPSSAS
LMR3_Mmus -TKNLLG---DKGSTPGETGPRKAGRSPANREKGPGPNRDLTSLVSRKKVPSRSLP----
LMR2_Mmus DAALASALSSDSTS--QDSLLEDSLSTP-IP-------TSEQSVETPDSLDSVDVREALL
LMR1_Mmus -TEATSGVFTDLSS--DGPHTEKSGIVPALR-------SLQKQVGTPDSLDSLDIPSSAS
LMR_Spur -----------------GYGTAGSNLLEGNDSTVTFTESFNTMSS---------------
AqueK333_Aque ------------------------------------------------------------
LMR3_Hsap VNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALEN---GEL
LMR2_Hsap DS-LGSHTPQKLVPPD---KPADSGY-ETEN---------------LESPEWTLHPAPEG
LMR1_Hsap DGGYEVFSPSATGPSGGQPRALDSGY-DTEN---------------YESPEFVLKEAQEG
LMR3_Mmus VNGVTVLENGKPGVPDMKEKVAENGL-ESPE---------------KEERALVN---GEP
LMR2_Mmus ES-LGSHTPRKLLPPD---KPADSGY-ETEN---------------LESPEWTLHPAPEG
LMR1_Mmus DGGCEVLSPSAAGPPGGQPRAVDSGY-DTEN---------------YESPEFVLKEAHES
LMR_Spur ----NPFSSSTSSEPGGFVSAVESAG-DRSL------EDSR----DHENNGFG---EFES
AqueK333_Aque -------------------QRESYRY-SRES---------------WDSFDDDYD-----
. :.
LMR3_Hsap RSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGP
LMR2_Hsap TADS-------------------------------------------------------E
LMR1_Hsap CEPQ--------------------------------------------------------
LMR3_Mmus MSPEAGEKVLANGVLMSPKSEEKVAENGVLRLPRNTERPPEIGPRRVPGPWEKTPET---
LMR2_Mmus TADS-------------------------------------------------------D
LMR1_Mmus SEPE--------------------------------------------------------
LMR_Spur SMG---------------------------------------------------------
AqueK333_Aque -------------------------EDEQ-------------------------------
LMR3_Hsap APTIGEPAPETSLERAPAPSAVVSSRNGG--------------ETAPGP-----------
LMR2_Hsap PATTGDGGH---SG--LPPNPVIVISDAGDGHRGTEVTPETFTAGSQGSYRDSAYFSDND
LMR1_Hsap --AFAELAS---EGEGPGPETRLSTSLSG--------------LNEKNPYRDSAYFSDLE
LMR3_Mmus ----GGLAPETLLDRAPAPCEAALPQNGL--------------EMAPGQ-----------
LMR2_Mmus AAAAGDSGH---SS--LPPNPVIVISDAGDGHRGAEGPPQSFTLGPQSSYRDSAYFSDND
LMR1_Mmus --AFGEPAS---EGESPGPDPLLSVSLGG--------------LSKKSPYRDSAYFSDLD
LMR_Spur -LSFGTP-----------------------------------------------------
AqueK333_Aque ----------------------------TDGVRSAPLPPTQFS--------------QEE
LMR3_Hsap ------LGPAPKNGTLEP---------GTERRAPETGGAPRAPGAGRLDLGSGGRAPVGT
LMR2_Hsap SEPEKR--SEEVPGTSPSALVLVQEQPLPEPVL-------PEQSPAAQD--SC-L-----
LMR1_Hsap AEAEATSGPEKKCGGDRA--------PGPELGL-------PSTGQPSEQ--VC-LRPGVS
LMR3_Mmus ------LGPAPKSGNPDP---------GTEWRVHESGGAPRAPGAGKLDLGSGGRALGGV
LMR2_Mmus SEPDKK--PEEVPGTSANALVLVKGQSPPESVV-------PEESSDVRE--GC-L-----
LMR1_Mmus AESEPTFGPEKHSGIQDS---------QKEQDLR----SPPSPGHQSVQ--AF-PRSAVS
LMR_Spur -----------------------------------------SEGD---------------
AqueK333_Aque EEEEE-------------------EPPLPPQDL-------PPDLTPNEQ--ID-W-----
LMR3_Hsap GTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQ--------------PRRLEPAP
LMR2_Hsap -EARKSQPDESCLSALHN-SSDLE-------------L--------------RATPEPAQ
LMR1_Hsap GEAQGSGPGEVLPP-LLQLEGSSPEPST---------C--------------PSGLVPEP
LMR3_Mmus GTAPAGGPASAVDAKAGWVDNSRPLPPPPQ---PLGAQ--------------QRRPEPVP
LMR2_Mmus -EAPQDKPDQSRVSTLQN-SCHSE-------------L--------------QETLQPTP
LMR1_Mmus --------SEVLSP-PQQ--SEEP-------------L--------------PEVPRPEP
LMR_Spur ------------L----------------------SSV--------------RETP--TP
AqueK333_Aque -------------------EESEPVATPPGVYP-TDEVINRTNPYATELQDEEEVSLPPP
LMR3_Hsap PRARP--EVAPE-GEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSE
LMR2_Hsap TGV--PQQVHPTEDEASSPWSVLNAE--------LSSGDDFETQDDR-PCTLASTGTNTN
LMR1_Hsap PEPQGPAKVRPGPSPSCSQFFL--------LTPVPLRS-----------------EGNSS
LMR3_Mmus LKARP--EVAQE-EEPGVPDNRLGGDMAPSVDEDPLKPERKGPEMPRLFLDLGPPQGNSE
LMR2_Mmus ADA--SRESCPVNDEASSPLSLLNSE--------PSSCDDLDTQEDR-PCTLASTGTNTN
LMR1_Mmus LGAQGPVGVQPVPGPSHSKCFP--------LTSVPLIS-----------------EGSGT
LMR_Spur GGQ--------------------------------------NSTSSDLFGDL--------
AqueK333_Aque LPAEE--DDIGTDEESLQPI-------------EPVKLDRF-------------------
LMR3_Hsap QIKARL-SRLSLALP-PLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGED
LMR2_Hsap ELLAYTNSALDKSLS-----SHSEGPKLKEPDIEGKYLGKLGVSGMLDLSEDGMDADEED
LMR1_Hsap EFQGPP-GLLSG----PAPQKRMGGPGTPRAPLRLALP---GLPAALEGRPE--EEEEDS
LMR3_Mmus QIKAKL-SRLSLALP-PLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGED
LMR2_Mmus ELLAYMSSTLDKSLP-----SHLESSKLKEPDIEGKYLGKLCVSGMLDLSEDGMDADEED
LMR1_Mmus EPQGPS-GQLSG----RAQQGQMGNPSTPRSPLCLALP---GHPGALEGRP---EEDEDT
LMR_Spur ---SQPSNPFDSSAASVSFGVGVESPAVKE-----------------------VSFDQLA
AqueK333_Aque -------------------------------------------------------ARVDS
LMR3_Hsap EDEDEEEDEEAAAPGAAAGPRGPGRA-RAAPVPVVVSSADADAARP---LRGLLKSPRG-
LMR2_Hsap ENSDD-SDEDLRAFNLHSLSSESEDE-TEHPVPIILSNE---DGRH---LRSLLKPTAAN
LMR1_Hsap EDSDE-SDEELRCYSVQEPSED-SEE-EAPAVPVVVA--ESQSARN---LRSLLKMPSL-
LMR3_Mmus EDEDEE-DEEAA------GSRDPGRT-REAPVPVVVSSADGDTVRP---LRGLLKSPRA-
LMR2_Mmus ENSDD-SDEDLRAFNLHSLSSESEDD-TEHPVPIIVSND---DGRH---LRSLLKPSAAE
LMR1_Mmus EDSEE-SDEELRCYSVQEPSED-SEE-EPPAVPVVVA--ESQSARN---LRSLLKMPSL-
LMR_Spur QNGE-D-KKDLHSFSAITLKEH-EKE-STD-VPPVGD--HEITPQGYAEVSAAAKK-S-Y
AqueK333_Aque RGFDD-SDEINTPMTETGGGRGAEEDSDDINVPVQS--EEKSTGKK---TKASKKEEKE-
.. : .: ** : . *
LMR3_Hsap ADEPEDSELERKRKMVSFHGD--------VTVYLFDQETPTNELSVQAPPEGDTDPST--
LMR2_Hsap APDPLPEDWKKEKKAVTFFDD--------VTVYLFDQETPTKELGPCGGEACGPDLSG--
LMR1_Hsap LSETFCEDLERKKKAVSFFDD--------VTVYLFDQESPTRELGEPFPGAKESPPTFLR
LMR3_Mmus ADEPEDSELERKRKMVSFHGD--------VTVYLFDQETPTNELSVQGTPEGDTEPST--
LMR2_Mmus AIEQLPEDWKKEKKAVTFFDD--------VTVYLFDQETPTKELGHCGGEAHGPGPSS--
LMR1_Mmus LSEAFCDDLERKKKAVSFFDD--------VTVYLFDQESPTRETGEPFPSTKESLPTFLE
LMR_Spur GMTMLTVTSGKKKKSIKILKEEDGEDAGDAASHVTMVTNGSSEMA---KDDG--IST---
AqueK333_Aque REKAKKKELKEKKKKEK-------------------QQRSIKKKKSKGGE----------
.::* . :
LMR3_Hsap -PPAPPTPP-HPATPGDGFP-SNDSGFGGSFEWAEDFPLLP-------------------
LMR2_Hsap -PAPASGSP-YLSRCINS--ESSTDEEGGGFEWDDDFSPDPFMSKTTSNLLSSKPSLQTS
LMR1_Hsap GSPGSPSAPNRPQQA-DGSPNGSTAEEGGGFAWDDDFPLMTAKAAFAMALDPAAPAPA--
LMR3_Mmus -PPAPPTPP-HPTTPGDGFP-NSDSGFGGSFEWAEDFPLLP-------------------
LMR2_Mmus -PAASSSSP-YLGRCMNS--ESSTDEEGGGFEWDDDFSPDPFMSKTT-SLLGSKPSLQTS
LMR1_Mmus GGPSSPSATGLPLRA-GHSPDSSAPEPGSRFEWDGDFPLVPGKAALVTELDPADPVLA--
LMR_Spur APPASGPGPN-LL-DL-DI-PVSGLDQGSGL-----------------------------
AqueK333_Aque ------------------------------------------------------------
LMR3_Hsap ----PPGP----------PLCFSRFSVSPALETP----------GPPARAPDARPAG---
LMR2_Hsap KYFSPPPPARSTEQSWPHSAPYSRFSISPANIASFSLTHLTDSDIEQGG-----SSE---
LMR1_Hsap ---APTPT----------PAPFSRFTVSPAPTSRFSITHVSDSDAESKRGPEAGAGG---
LMR3_Mmus ----PPGP----------PLCFSRFSVSPALETP----------GPPARAPDARPAG---
LMR2_Mmus KYFSPPPPARSAEQSWPHVSPCSRFSISPANIASFSLTHLTDSDIEQGG-----SSE---
LMR1_Mmus ---APPTP----------AAPFSRFTVSPTPASRFSITHISDSDAQSVGGPAAGAGG---
LMR_Spur ----APGL----------TLGFGTIEVEVSNDGGDAV-------VVQSQSPDSVEFGSFE
AqueK333_Aque ------------------------------------------DD---------KEKGGDE
LMR3_Hsap --PVEN
LMR2_Hsap D-GEKD
LMR1_Hsap E-SKEA
LMR3_Mmus --PVEN
LMR2_Mmus D-GDKD
LMR1_Mmus R-YTEA
LMR_Spur DVSKEL
AqueK333_Aque P-ALVW