PHKg2_Hsap MTL---DVGPEDE----LPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVK
PHKg1_Hsap MTR---D----EA----LPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVK
PHKg2_Mmus MTL---DVGPEDE----LPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVK
PHKg1_Mmus MTR---D----DA----LPDSHSAQTFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVK
Y50D7A.3_Cele MGMLIVDTDHEDSDESQHYRHEEDQGFNAAYESKEVLGRGLASTVRRCIEKGSGQHFAVK
PHKG1_Spur MTV---DDNQDET----DFGIEYDDAFSSKYMAKHILGRGVSSTVRLCCNRNTNEEYAVK
PhK__Dmel MAK---DE-EDDL----LPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAK
AqueK079_Aque MAD---S-GGSTS----FLQGTDEGEFHNKYEPKEILGRGLSSTVRRCVSRDTGLEYAVK
* . * * .*.::***::*.** * : : .:*.*
PHKg2_Hsap IMEVTAE-RLSPEQLEEVREATRRETHILRQVA---GHPHIITLIDSYESSSFMFLVFDL
PHKg1_Hsap VIDVTGGGSFSPEEVRELREATLKEVDILRKVS---GHPNIIQLKDTYETNTFFFLVFDL
PHKg2_Mmus IMEVSAE-RLSLEQLEEVRDATRREMHILRQVA---GHPHIITLIDSYESSSFMFLVFDL
PHKg1_Mmus IIDITGGGSFSSEEVQELREATLKEVDILQKVS---GHPNIIQLKDTYETNTFFFLVFDL
Y50D7A.3_Cele IVDISTE-KQSENEAKRLLEETISEVEILRQLS---GHPSIIKIHDFYQTPSFLFAVFEM
PHKG1_Spur IIDITGQNHGGDNRAEAIQEEYRNEILILNKMAEGEGHPNIR------------------
PhK__Dmel IIDLGATTESGETNPYHMLEATRQEISILRQVM---GHPYIIDLQDVFESDAFVFLVFEL
AqueK079_Aque IISRT--------QDEVINESIAAEIEVLNLLP---KHPNIIQLYDKFETPAYIFLVFEL
::. . : : * :*. : ** *
PHKg2_Hsap MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRL
PHKg1_Hsap MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKL
PHKg2_Mmus MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRL
PHKg1_Mmus MKRGELFDYLTEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKL
Y50D7A.3_Cele APRGELFDVLNSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILCIDEERIVI
PHKG1_Spur ----ELFDYLTAVITLSEKKTRAIMRSVISAVAYIHSHNIVHRDLKPENILLDANLKVKI
PhK__Dmel CPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKI
AqueK079_Aque ACGGELFDYLTKVVRLSEKKTRLIMQQVFSGVHHMHSSCVVHRDLKPENILLDKNGNVKI
**** *. : ::**.:* :*: ::. : :* :****** **** : .: :
PHKg2_Hsap SDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMD-ETHPGYGKEVDLWACGVILFTLLA
PHKg1_Hsap TDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMN-EDHPGYGKEVDMWSTGVIMYTLLA
PHKg2_Mmus SDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMD-ETHPGYGKEVDLWACGVILFTLLA
PHKg1_Mmus TDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMD-DGHPGYGKEVDMWSTGVIMYTLLA
Y50D7A.3_Cele SDFGFATRIPRGKKLRDLCGTPGYLAPETIRCQWY-DNAEGYSLEVDEWALGVIMYTLLA
PHKG1_Spur SDFGMAAELTEGVYLRELCGTPGYMAPEMLKCSMGLENISSYGQKIDLWACGVIMYTLLV
PhK__Dmel TDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMF-EGSPGYSQEVDIWACGVIMFTLLV
AqueK079_Aque SDFGFATRVEENDELSDLLGTPGYLAPELLKRSTE-PDAPGYNKEVDLWACGVIMYTLLA
:***:: .: . * :: ***.*:*** :. . .*. ::* *: ***::***.
PHKg2_Hsap GSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQH
PHKg1_Hsap GSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAH
PHKg2_Mmus GSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQH
PHKg1_Mmus GSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAH
Y50D7A.3_Cele GCAPFYHRKQLMMLRLIQQGKFEFRNEQWANITAEAKNLITQLLQVDATKRISSKECLAH
PHKG1_Spur GRPPFWHRKKMLMLRAIMEGRYRFGSPEWDDISDTPKDLISKLLVVDPKLRLTAEEALEH
PhK__Dmel GCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRH
AqueK079_Aque GFPPFWHRKQLIMLRKIMNGDYEFVSPEWDEISDAAKDMIRRLLTVDPKQRMTALEALEH
* .**:**::::*** * .* : * . :* : : *::: : * *:. * : : * *
PHKg2_Hsap PFFERCEG----------------------------------------------------
PHKg1_Hsap PFFQQYLV----------------------------------------------------
PHKg2_Mmus PFFERCEG----------------------------------------------------
PHKg1_Mmus PFFQEYVV----------------------------------------------------
Y50D7A.3_Cele EWMIPIAQQQAPQ-----------------------------------------------
PHKG1_Spur PFFQQTEV----------------------------------------------------
PhK__Dmel PFFNQMVLM---GDRRHPAPPIAPAQTNSRHLLQPEASSYRFGQLNSSCAGAPNYLYCAP
AqueK079_Aque PFLESKPA----------------------------------------------------
::
PHKg2_Hsap ------------------------------------------------------------
PHKg1_Hsap ------------------------------------------------------------
PHKg2_Mmus ------------------------------------------------------------
PHKg1_Mmus ------------------------------------------------------------
Y50D7A.3_Cele ------------------------------------------------------------
PHKG1_Spur ------------------------------------------------------------
PhK__Dmel QSSYSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNSALASASSHKTL
AqueK079_Aque ------------------------------------------------------------
PHKg2_Hsap ------------------------------------------------------------
PHKg1_Hsap ------------------------------------------------------------
PHKg2_Mmus ------------------------------------------------------------
PHKg1_Mmus ------------------------------------------------------------
Y50D7A.3_Cele ----------------------------MVPVV------------------------EVE
PHKG1_Spur ------------------------------------------------------------
PhK__Dmel TAMVYYQQQPQQHQTQQQQQQYQQQQTTQLPVQLQLQHPLLQTGGDGKQSVYAPPTVQ--
AqueK079_Aque ------------------------------------------------------------
PHKg2_Hsap --SQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCA
PHKg1_Hsap --EEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYA
PHKg2_Mmus --SQPWNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCA
PHKg1_Mmus --EEVRHFSPRGKFKVICLTVLASVKIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYA
Y50D7A.3_Cele LVKDQTSERARKRFKTAIIWVRFFQRLAKYKYLKTVIDRDVLRKRPFRDRDIRHEAESSM
PHKG1_Spur --PIGTTFNARRKFKAACLVVYGVVRLRH-YCGQRIISPHSIQENPYGVKAIRKALDGCA
PhK__Dmel -LRKQSRFNARKKFQFAILVIRAIIRIRRLRFTAEPLHVEEAIRDPYRVKVLRKVIDGCA
AqueK079_Aque --E-FVIFSAGRKLKAILWCVRFCVAVDRSRKTPKVVTIKDIGTSPYENRYIRKLIDTCA
. ::: : : : . *: : :*: :
PHKg2_Hsap FRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEE---GDS--A---------------
PHKg1_Hsap FRIYGHWVKKGQQQNRAALFENTPKAVLLSLAE-E-------------------------
PHKg2_Mmus FRLYGHWVKKGEQQNRAALFQHQPPRLFPIAATELE---GDS--G---------------
PHKg1_Mmus FRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEE-------------------------
Y50D7A.3_Cele FSVYGHWVNRGFYYSRDMLFANKPRPKIAKKTDGAAAVEQKLKVPPIALRKFNFLAEIFQ
PHKG1_Spur FNIYRHWVKKGQGQDRAALFANSPKMDIKNLNNSLSSSQQTTP-T---------------
PhK__Dmel FRVYGHWVKKGEGQNRAALFENTPRTELHALY----------------------------
AqueK079_Aque FHIYSPWVKRGEEQNRAALFETAPKVAMKHPNFYISS-----------------------
* :* **::* .* ** * :
PHKg2_Hsap --------------------AITED-----------------EAVLVLG
PHKg1_Hsap -----------------------------------------------DY
PHKg2_Mmus --------------------AITED-----------------EATLVRS
PHKg1_Mmus -----------------------------------------------DF
Y50D7A.3_Cele KKKLDYFDWKMFKIPDFNSNSVKNSRFSLRFYVKNIEFPLFPIIFLPPP
PHKG1_Spur --------------------MSRSS-----------------STTGMAT
PhK__Dmel -------------------------------------------INNLSR
AqueK079_Aque ------------------------A-----------------AVTFTFT