Alignment of Family PI3K

Protein (view, download) , Domain (view, download) 
29569_Tthe_PI4K  MATGGIE-PAC-SK----------------------------------------------
13773_Tthe_PI4K  MLEHLLE-SALIKLYQGNFTDSKQIVQAISDILLDETLDDSQISLCNSKIFNSDLNLFTY
20618_Tthe_PI4K  MSHIMQE-I-S-KLFEQFKKAKNQES---ERL-------------------AADLQQ-LY
20619_Tthe_PI4K  MQEEKLL-K-K-NT----------------------------------------------
n8_Tthe_PI4K     MQQGSQN-LQS-RDISQ------------D------------------------------
n29_Tthe_PI4K    MRLNLNRNIYQ-KLKE--------------------------------------------
n73_Tthe_PI4K    MSEENSI-IL--KTK---------------------------------------------
n131_Tthe_PI4K   MDRNSHS-R----NGK--------------------------------------------
n502_Tthe_PI4K   AYAFSLQSLQK----K--------------------------------------------
n508_Tthe_PI4K   MDAISIV-IK--------------------------------------------------
n545_Tthe_PI4K   HFL-NNR-I---------------------------------------------------
n679_Tthe_PI4K   MKKGPTE-YIQ-HTL----------L---DQL----------------------------
n737_Tthe_PI4K   MAEDTQK-----------------------------------------------------
n858_Tthe_PI4K   MAQFFNQ-KQK-ENEEE------------A------------------------------
GK310_Glam_PI3K  MQVSIIS-PKG-A-I---------------------------------------------
GK311_Glam_PI3K  MKGLNVE-INS-M-V---------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  LENNRTYKDNLQAQIRKGLFRTIAAYIKLRKLKVFEYIELICKNCMSLFKKEESN-QAKE
20618_Tthe_PI4K  LKNNQYY-----DEIYHGLIK--------------------------LINSNDI--NEKY
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ----------------------------------------------------------KY
n29_Tthe_PI4K    -----------------------------------------------------NSQKSDN
n73_Tthe_PI4K    -----------------------------------------------------KP-HGIL
n131_Tthe_PI4K   -----------------------------------------------------SPISSSN
n502_Tthe_PI4K   -----------------------------------------------------AV-RKKQ
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -----------------------------------------------------NP-----
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ----------------------------------------------------------QY
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  --------KFL--MFDQFQML-------------------IYL--EATIFNDN--IG---
13773_Tthe_PI4K  TSLS-PIIKIIK-CIDNSELL-----EKII----DPKNTISA------LLN---------
20618_Tthe_PI4K  NSLI-GIEQISY-VVQEDQYL----N-------------LWSKFN--SLVFQLLE-----
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     AVTC-RIEKFII-CVDPDSRQ-------------------IYGLN--PQNNDLYIFL---
n29_Tthe_PI4K    -QIT-RQDEIKF-CQIIQGSLVGQQLL-SSNYDIMPFQLGLILWK--NLPNEFSSVL---
n73_Tthe_PI4K    ASVF-CCKCFKC-CQEIDQSL-----L-TS----NDRKKILN------------------
n131_Tthe_PI4K   -NLG-DQKELNQHDYI---------------FSLE------------RVQQQIPI-----
n502_Tthe_PI4K   -ILA-SIKRYII-IHHFIKKL-----I-LY-M-K--KKALESIVN--RRTNRVSPSKLTL
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -----P-VKFKI-CC---------------------------------------------
n737_Tthe_PI4K   ---------LLI-CVDPKTKW-------------------FYTIN--TNTNELRIEE---
n858_Tthe_PI4K   -------EKWLI-CVDPKSKM-------------------FYTVN--SVTNELHIET---
GK310_Glam_PI3K  CTFCTRPDVAIV-ALEFESRC----RLGLE----DTPILLQYTSKSATFTNELSTLG---
GK311_Glam_PI3K  ----------------------------------TPSYAV--------------------


29569_Tthe_PI4K  E------------TTQNRINQKI-----VIGLSKDLLKSKEAKA---SQQNFEQANRLNS
13773_Tthe_PI4K  EIK----------------------------------------FCKPTQKVKGSIWNLIG
20618_Tthe_PI4K  -QTGD------------------------------------EKVIKKSAEVYGRLLRLGG
20619_Tthe_PI4K  -------------------------------------------------EVFGRLLRLGG
n8_Tthe_PI4K     DEKLKNQIDYDGDRVQAEEMQNVKF---LDSLREQFLEDNK-------------------
n29_Tthe_PI4K    DN---------------L--QNLIGQGALTKYLN--------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -P---------------Q------------------------------------------
n502_Tthe_PI4K   S-------------------NDMVEKYMPIRIYK--------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   D-----------------AEQNVVM-----------------------------------
n858_Tthe_PI4K   D-----------------A--DDIM-----------------------------------
GK310_Glam_PI3K  EC---------------LANLNVVS---VDSLQFHVLPLDL-------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  IEQSNQKNR----VQAKQEGIQGSGFLQVQQSLSVNRPS---------------------
13773_Tthe_PI4K  IIFQFFTDQLEDDLK---AEIQTVCFKELQVQMASQKPEVSYVSGMFKSFRYS----LKE
20618_Tthe_PI4K  TRITNL----------------------LTDQIQKPIHW-------------IFKN-SGD
20619_Tthe_PI4K  QRVQNV----------------------LVGYISNIIES-------------LFLTSTKD
n8_Tthe_PI4K     --------------------------IELSQQVSKNLN----------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    -------KLI-----------------------------------------KN----TSD
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ----------------------------------------------------D----LSE
n679_Tthe_PI4K   ---------------------------------------------------------IND
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  --------------------------ASTPNH-----Y----------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  IHL------------------SNKELEDLYKMIKIGITEIKDVQILDDSKEIIDKVLGLI
20618_Tthe_PI4K  NKKFSGLLVLKELLEQASFVTF--------------------KQFISNTEDYRTNLWNLI
20619_Tthe_PI4K  NQKYASLLVLKELLEQSPFITF--------------------K-IIANTENFRSKIWSHI
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    PQL------------------Y------------------------D-AHGL-S------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -----------DIL----------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   KHI------------------W--------------------------------------
n679_Tthe_PI4K   QKK-----VL---------------------------------RYFFNDEDGSSKLENLE
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ---------SSNNLMDQT-AQIHIQKQDSNSAKSSKSSISYNSETNYLKMNAQP---SN-
13773_Tthe_PI4K  SHNNRDVKENASDCLESLMALLAI-ELDSSYKNH---ELSFNY-----------------
20618_Tthe_PI4K  KHKTTLLREAALSFFDVLLKQISLKEQDIQDREY---NTFFTDICQSMNARQEEVVIGNI
20619_Tthe_PI4K  KSKNILVREAALSFFDQYMQHISLKEQEVQEKEY---SAYYTDIESYLKQKEEEMIIGNI
n8_Tthe_PI4K     ------------SIS--------------------------NHQTDVIKQNGQL---ST-
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ----QNIKKKNSQISDPIQILI-------GL-----------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   AMV---------------TAQLVVNEKKI-------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -------IKER----V------------------------------------EQITEEPV
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  SALKILVTYPNSEQF---------------------------------------------
20619_Tthe_PI4K  AVLKIIFSYPSQEQF---------------------------------------------
n8_Tthe_PI4K     -----STIQQNGQQTNQEQALNPAVNAVDNAILGVSEIKKKYSIDDYRIKGKKAIE----
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------------------------------------RQKADEAIK----
n858_Tthe_PI4K   -----------------------------------------------KDAAKKAIN----
GK310_Glam_PI3K  ------------------------------------------------TSEPETVF----
GK311_Glam_PI3K  -------------------------------------------------KVAPTV-----


29569_Tthe_PI4K  DEHLDFKYQKLLDVIKGSGDKNNLGF----------------------------------
13773_Tthe_PI4K  ------IIQKMSFLINQE-----------RQQIYTASITVIIKSIGIFSKAIAKHLGQDQ
20618_Tthe_PI4K  ---NDQQFSQMCMYVLSK-----------KD-ENSNIQKTVIEALPALAKFKKQAFAEKF
20619_Tthe_PI4K  ---TDTQYSNMCKYVLSK-----------KEHTYQSIQKIVIDTLPILSKFKRQHFCENF
n8_Tthe_PI4K     NIEK---IIQINDG----------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------Y-----------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ---------------------------------QPAQQTLFID---------RMLFEQNI
n737_Tthe_PI4K   DLYK---IINLDDS----------------------------------------------
n858_Tthe_PI4K   DLRQ---IIDYDKS----------------------------------------------
GK310_Glam_PI3K  DLLESWQYHKLDTI-----------LLSFT------------------------------
GK311_Glam_PI3K  ----FLQHIVLDKS-----------LLAGH------------------------------


29569_Tthe_PI4K  --------LQQKIDY-LTMISNRLQISLFDLLNLLPS-----------------------
13773_Tthe_PI4K  LQLFFKQMINLSEVRL-----------------------------------LKHIEKDGV
20618_Tthe_PI4K  FIKTTEFLLQRINPPKAKSITHELIVSYYDTLNKISQ-----------------------
20619_Tthe_PI4K  LCETIDHIRNLIGSNKFKSPSQDLLISYYDTLDKICS-----------------------
n8_Tthe_PI4K     -------------------------------------------------NWLINH-----
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ---------------------------------------------------LSENDEDKN
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -------------------------------------ERLKHPYKNLACELLLAQ-----
n508_Tthe_PI4K   -----------------------------------------DPENNNL------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -------IFNY-------------------------------------------------
n737_Tthe_PI4K   -------------------------------------------------YWLFRS-----
n858_Tthe_PI4K   -------------------------------------------------SWLFES-----
GK310_Glam_PI3K  ----ILHYQSLVAEA-LVSKKNKLMITAHTQPDISPS------------HPFLTS-----
GK311_Glam_PI3K  ----MLHGF---------------------YPDLHIIFKLMTPPDTLLAPPMNSS-----


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  NSVVDFQPVEDETMKKGTSFKTILYRQKQVISFITSFANIISQLDKLYEDESQSLLRLCM
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    DQ----------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  --------------------------------------------------KYLAQLF---
13773_Tthe_PI4K  VGFKQFSSFYEKYKEPLNEGIVQLMREMKKHQSIYIIWLENLVQNGLVQS-------IKL
20618_Tthe_PI4K  --------------------------------------------------CIDSTIYAKL
20619_Tthe_PI4K  --------------------------------------------------SLDISIIKKI
n8_Tthe_PI4K     ------------------------------------------ERADQYRR-------RKL
n29_Tthe_PI4K    ------------------------------------------DF----------------
n73_Tthe_PI4K    -----------------------------------------------FMQ----------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------QFQKQIQQ-------EQM
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------EQAKELQR-------RKI
n858_Tthe_PI4K   ------------------------------------------EQAKRFQR-------RKI
GK310_Glam_PI3K  ------------------------------------------PLARDLATKVTSAILRAI
GK311_Glam_PI3K  ------------------------------------------IQSTIICK-------KTQ


29569_Tthe_PI4K  QDYKQQENVMVNIILASVSGLSQP--NKIFEDIKIDL-----------------------
13773_Tthe_PI4K  PD-------------NSFLSM---------------------------------------
20618_Tthe_PI4K  PENMKD---L---VF--------QSIQNITRQIR--------------------------
20619_Tthe_PI4K  PDDKKK---L---IF--------DEIKRVCKTIQ--------------------------
n8_Tthe_PI4K     PNY---------------------------LLQRTDQ-----------------------
n29_Tthe_PI4K    -----------------------------------------------DFESQSYPLLNV-
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ESQ---------------------------KFGKEMSLKTIQQNQHQQIDQERNDISTLQ
n508_Tthe_PI4K   ---------------------------------G--------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   --KYKD---L---SY--------NSIIAITLWCSQ-------------------------
n737_Tthe_PI4K   PSY---------------------------LLNKDCS-----------------------
n858_Tthe_PI4K   PSY---------------------------LLHKDSS-----------------------
GK310_Glam_PI3K  PTHNQNKS-VDLGIF--------Q--QEIADWIAMDL-----------------------
GK311_Glam_PI3K  LTY---------------------------VWNSQQL-----------------------


29569_Tthe_PI4K  -----------------GDKFDYENQYLKAHCQNYED--------CLNQDEQE-------
13773_Tthe_PI4K  --------------------------------QEYYE--------TLKSCSQFWKSLF--
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     -----------------NHPTYICQSPLSEV-----------------------------
n29_Tthe_PI4K    --------KL----KAIV------------------------------------------
n73_Tthe_PI4K    -------------------------------------------------------NLL--
n131_Tthe_PI4K   --------NF----PPKE------------------------------------------
n502_Tthe_PI4K   NKRTNNDVSILNENQQDQTNAFINQQNFENA-----------------------------
n508_Tthe_PI4K   ------------------RHSVFDI-----------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------KYPKYLCQSNLSLA-----------------------------
n858_Tthe_PI4K   -----------------EYPTYLCQSNLSLA-----------------------------
GK310_Glam_PI3K  -----------------RAQLSF--SVIEQHVLNASSCSSAHSLPP------RQERLLPG
GK311_Glam_PI3K  -----------------TFPISI--SNLPQA-----------------------------


29569_Tthe_PI4K  -QQSLEDDEELEELTP----------QIKTRIFFSRYIIPLVLHQLIDFKQDPSIQMSSI
13773_Tthe_PI4K  N-CQLWTDETLHHFS----------AQFFQY-----------------------------
20618_Tthe_PI4K  --------QDLQEKKP----------YISFRIQCLMSIIKNFQHKYQDLINDEDLLINNI
20619_Tthe_PI4K  --------KDLQDKKE----------YIPSRVTCLQNIVKVFSTRYSELI-DEENLIDDL
n8_Tthe_PI4K     ------F--------VK-------------------------------------------
n29_Tthe_PI4K    ----------------K-------------------------------------------
n73_Tthe_PI4K    R-CRTNQRDDVEYYI----------PQLCSF-----------------------------
n131_Tthe_PI4K   ----------------Q-------------------------------------------
n502_Tthe_PI4K   ------Y--------QD-------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -------RDDLEFYL----------PQICNF-----------------------------
n679_Tthe_PI4K   --------KNKDEKKP----------LGCTTISLFDDQFRLRQGKYHLYIWPDTL-----
n737_Tthe_PI4K   ------F--------SK-------------------------------------------
n858_Tthe_PI4K   ------F--------AN-------------------------------------------
GK310_Glam_PI3K  KEGSLPD--------SQVSSLHKLGPC---------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  LGRLEDIYGMQQSQAQLGSAQNINTQDSGGSLSQNSNASQNLFIQ---------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  LF----------------------------------------------------------
20619_Tthe_PI4K  IF----------------------------------------------------------
n8_Tthe_PI4K     -----------------------------------EVTI----II---------------
n29_Tthe_PI4K    -----------------------------------NLEI----NILS-------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -----------------------------------S------------------------
n502_Tthe_PI4K   -----------------------------------QNEI----NLFRNNSNNFENSGKYF
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------------------------VNSI----NL---------------
n858_Tthe_PI4K   -----------------------------------VNSI----KL---------------
GK310_Glam_PI3K  -----------------------GVKNNSGIDHTHMNPS----HN---------------
GK311_Glam_PI3K  -------------------------------AHFHISIY----VH---------------


29569_Tthe_PI4K  --------------KV-----------------------------------Y-I------
13773_Tthe_PI4K  ---------------------IIQLLENTDLSYKVVYTQQI-EEDEIKDKNQME------
20618_Tthe_PI4K  ---------------NGLYPQSIEFLKH---------IQKY-NR----------------
20619_Tthe_PI4K  ---------------NGLYPQTVEFLEN---------IQSY-KMDEIKENTS--------
n8_Tthe_PI4K     --------------KV-----------------------------------N-L------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------IA----------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   FLFLVNILSNNLKVQ-----------------FNQANVESFQDEDEIQCENQEDGGLSKD
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------FV----------------------------
n679_Tthe_PI4K   ------------------------------------------PD----------------
n737_Tthe_PI4K   --------------NV-----------------------------------N-L------
n858_Tthe_PI4K   --------------VV-----------------------------------L-L------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  --------------GV-----------------------------------L-L------


29569_Tthe_PI4K  --TNLREFYRSLKFFMEKIY--RKNNDKAQYVL--------------------------S
13773_Tthe_PI4K  --IEQ-----DKESKIQDIIREIQQVQYVANNEVDLQFFYRVTLLFDSVLPSIKPALFSN
20618_Tthe_PI4K  ----------------------KERTRTEVS----------------------------S
20619_Tthe_PI4K  ---------------VSEEN--RKKEKKEFS----------------------------T
n8_Tthe_PI4K     --INF-------------------K-----------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ----F-----QQEFKVQKMVNYIKQAGQINFYFAHLL-----------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   IECQQ-----NQENQVQQQQNP--------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ----F-----HEELKNDSLKEFLKKAGKIDFFFGHML-----------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   --DEY-------------------I-----------------------------------
n858_Tthe_PI4K   --GNY-------------------E-----------------------------------
GK310_Glam_PI3K  ------------TILIENLQ--RRIDESGAC----------------------------A
GK311_Glam_PI3K  --GST-------EF----PL--YNE-----H----------------------------F


29569_Tthe_PI4K  Y-----------------------------------------------------------
13773_Tthe_PI4K  YI-YQFYKSIILKLRKLPRSIVLLKLLRCLNEYIEKNNILKGLKKYI-------------
20618_Tthe_PI4K  SIQYRLLLCIITILSKH-KNL---------------------------------------
20619_Tthe_PI4K  FIQYRLLLYIITTLQKQ-RNV---------------------------------------
n8_Tthe_PI4K     -------------------SQ---------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------YFYI-----------------RSLSYIVNKNE--------KYQLLAIEKMQLEL
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------CFYL-----------------KSVAQTVNKNQ--------IQDIPQVWNVLNEF
n679_Tthe_PI4K   --------------TSY-TSI---------------------------------------
n737_Tthe_PI4K   -------------------NQ---------------------------------------
n858_Tthe_PI4K   -------------------DK---------------------------------------
GK310_Glam_PI3K  HLDWEVVTASLDGVENP-LGV---------------------------------------
GK311_Glam_PI3K  ALRCMMHTCLIKPIAYT-DDQ---------------------------------------


29569_Tthe_PI4K  -----------------------LQKICKNE---RDYELDQTLFSYEDLK----------
13773_Tthe_PI4K  -KKDITSQIKIFFSELYKNLGKYQ-DEL-LI---D-----------CLKTMLSIPFEVLL
20618_Tthe_PI4K  ---------------FP------Q---SLNPNND-KDKNFYQKLILNTDK----------
20619_Tthe_PI4K  ---------------TP------L---TLPPVND-SQKKFQLKLRQYEDR----------
n8_Tthe_PI4K     ---------------LY------D-KQM-LI---N-----------KEKT----------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    YD---------FFSEHY------S-NKY-LT---A-----------KEL-YKEINQKQ--
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -------------------------------IQE-EQCSVCLIEFQESDQ----------
n508_Tthe_PI4K   --------------------------------------------KPNKQQ----------
n545_Tthe_PI4K   FS---------SFVEFY------S-SKQ-LM---S-----------AEM-VENLAMGK--
n679_Tthe_PI4K   ---------------TP------G---LVTDDN---------------------------
n737_Tthe_PI4K   ---------------LR------E------------------------------------
n858_Tthe_PI4K   ---------------LQ------DWKQE-PP---Q-----------NEKK----------
GK310_Glam_PI3K  ---------------SP------AS--PLVPLNPISYPHFTLVFSFPEDT----------
GK311_Glam_PI3K  ---------------IS------E---ELPP---IE-LSFELALPHSEDR----------


29569_Tthe_PI4K  -------------------------R--DRIV-L--------------------------
13773_Tthe_PI4K  IDNYSFFRKNLIVALKKGFELGVQNVSMGFAAIECLQKIIKRSKNRVVFKYLKLVIPYLS
20618_Tthe_PI4K  -------------------------TLSTDEKAIANAI----------------------
20619_Tthe_PI4K  -------------------------I--KGDKEISNAI----------------------
n8_Tthe_PI4K     -------------------------T----------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    --NHN-------------YQDQNGHYVAPNAEEQQIAD----------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   --KYAVP-----------YKLNKSNNGNSNEANMKIKQ----------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   -------------------------Q--EEK-----------------------------
GK310_Glam_PI3K  -------------------------T--DRRPAI--------------------------
GK311_Glam_PI3K  ------------------------------TRTI--------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  EYLSITKGELEEI----TSDMKYKVQSNNQQRDIFNLTVSELGQRKKDLIERVTNLLGDI
20618_Tthe_PI4K  ---QTLSTFGFSN----YENELANFVK---------------------------------
20619_Tthe_PI4K  ---QTLSTFKFKT----YEKELTNFLK---------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ---DVIQKYGTTEQDEIKQYPQFKLKSTNI------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ----IRITICDHI----FH-----------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ---EVISSYGTSY----YQRHKINILPEDI------------------------------
n679_Tthe_PI4K   -------------------IKQINFSH---------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  GGESHLIVLSEKGFQGNVERQLLSEFENLQISKKGVSLISWDYEAKVLFPLPLLAKKIDI
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ---ILKNY--KRKIILNE--------SN------LKNPRTFTNNQTQVCNPENI------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ---SLQNYINIQDFIQIK--------ER------VESSQEVEN-MDNGIPPENQK-----
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  NLTKLLPRMVELTLNPDDKIKVYACEAIHAITIYMIGTQASSIQGGQKKRGRDMENLIKS
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  KEEFSKIYSKLFPTIFSIGSNSSHPSCQLMNQLILQISRWFANSKQLESPEVAELLDNIM
20618_Tthe_PI4K  --------------------------------------------------------DNVL
20619_Tthe_PI4K  --------------------------------------------------------DNVL
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ---------Q---------DEM--------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   --------LN-------KETEI--------------------------------------
n679_Tthe_PI4K   --------------------------------------------------------QKTE
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  NFISSKDNNNLRELA--ANCLGQFIKWTLKQN--TEQEIKVNHSNIKSALRRIISFSGQP
20618_Tthe_PI4K  DYLDNK-NKNIRKAAAKAGCLLYVK-KERGQS--I-------------------------
20619_Tthe_PI4K  DYLDNK-NKIIRKAAAKAGCLLCVK-KGKDNL--I-------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -----------------SECLLQWL-KSQENCPNC-------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   QAFTNV-NKFPQK-----------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  --------------------------------------------------------YRL-
13773_Tthe_PI4K  DLSKRFGALLALKEVVNNIKNESFLVDKFIMETIQTSMRIVQKTGVSNEVEDNFNILIKL
20618_Tthe_PI4K  ---------------SKNIMYE--ILEKFMSVAISDSEDEIRQTMLK-SLNENFDQYLN-
20619_Tthe_PI4K  ---------------SKSVMYK--ILEKFMSVAVSDAEDEIRQTMLK-SLNENFDQYLI-
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ---------------RKDLQRR--KLKYWYSIQVRKQ---LRIMMND-RSAYSINLFLG-
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  AMSGTKK----------------------------------------------LL---FN
13773_Tthe_PI4K  QTNIIQK----------------------------------------------NYKTLK-
20618_Tthe_PI4K  EPNYLKK----------------------------------------------LF---L-
20619_Tthe_PI4K  EPIYLKK----------------------------------------------LF---F-
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   QPKSKSTTFGEQVAESNQQQQFYRKTPMFPFNKVKQLKRFNSLQGEFYHNSQTQ------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  YLQD------------KQILTKYAGNCIFDFKKKEIFLDYYKRFITPAEASLS------N
13773_Tthe_PI4K  AKNENRSGQFKLLDSLLDWLYSYGFF----------------------------------
20618_Tthe_PI4K  CVNDSNTQVQQLVLTILCRLSRYNPSDIIPFLKKTLF-EFL-------------------
20619_Tthe_PI4K  CVNDSNLEVQQLALTTLCRLSKYNPSDIVPFLKKTLY-EYI-------------------
n8_Tthe_PI4K     -----------------------------N-----------------------NQPLE--
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------GNIL------------------------N------N
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------------------------------------------KKPAEVD
n858_Tthe_PI4K   --------------------------MIKD-----------------------DKPIK--
GK310_Glam_PI3K  ----------------------SRSWCISDEH--RASLDKTTAITVDAQQSLS------S
GK311_Glam_PI3K  ----------------------ANTVCYAPEGLFRKTSMGSITTTADAHLATAKSPAHVS


29569_Tthe_PI4K  G---MDDTVFR-------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ----DQYSVK--------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   GQKTETDNIQQTNQLGQNNSKSIQRPTQVEYQEVSFNGAIVRIPKPKIETNTQKVIEVEN
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   W---DCKSLT--------------------------------------------------
n858_Tthe_PI4K   ----YEKRIE--------------------------------------------------
GK310_Glam_PI3K  N---LENTIT--------------------------------------------------
GK311_Glam_PI3K  L---LEMNAL--------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   EEEEEKKEQLEEQNQDICIQQIQNEQIIEQNSKIKNDSLSIQQENKSDLNQNGSNKHIDL
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   KQNDNQNMFECISLNNSIQIEDCQQENSQCFRKRKHLRESWFKKSEQSKQILNIEEDNSS
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   MKTIEKDNFNQKIEEQQIAGDYKSIRKDSLNQENIKQNISDDESIINLNINQTNNQIKNH
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   IEIKTKQIDLQNQQQQKNVNLDLSETSKNKQNDINHSIKESNKSMNENNFGQKLKQSDDQ
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   FNCELIDLENRQESPCKIDSITQKLELNEDFDPSIFRLQTEDLTKSNQIKQVNKCKEKSH
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   TAIRNNKKIIQQDTTPSKRTKQTKQTKQLNLNSLSSKDTNPSPKLFITPQKNSFNNHQIQ
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   KYQPCSSPILLQNASSILNNKIKTQNETLVSQQEHKIFLKTVITKFNKFNSKLASIMNKR
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ----------------------------------------------------------FL
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ----------------------------------------------------------LL
n502_Tthe_PI4K   PVKETVEQKRPTWFSKLPVNIEELQQTGALLGITTAPDDSFSQSPTKDRDSDHISTKELF
n508_Tthe_PI4K   -------------------------------------------------------TRRIL
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    NSFIMKLKTNE---KVNYNQFSTLWINQLILHDNKNKLIDLMDIKLLKDKLVEILNLIIE
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   QMFNAELFTTEYLIEYLYKKFETPGVHEYLVN----------------------------
n502_Tthe_PI4K   KLFNRKDFKIDQLLKHFYYQYTKIGIHDYLVN----------------------------
n508_Tthe_PI4K   QELNEPSIQIEKLLKYLYLFYEYIGVHDFIIN----------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ---------------------------------------ISAN-----------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ---------------------------------------IKAE-----------------
n29_Tthe_PI4K    ENQKLKNSMSKREQYMNLFKENLNELYLVIGLANKFSQFLSFSLSTPDNLVNIYEFCFQF
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------K-LYAVPHYE--------------------------------------------
n502_Tthe_PI4K   ------K-LYSYGEAD--------------------------------------------
n508_Tthe_PI4K   ------K-LYNYSEAE--------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ---------------------------------------IEAG-----------------
n858_Tthe_PI4K   ---------------------------------------IEAG-----------------
GK310_Glam_PI3K  ---------------------------------------ISPL-----------------
GK311_Glam_PI3K  ---------------------------------------LSSS-----------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ---------------------------------NSSYLVRKSSFELWQSILNREDSDISC
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ---------------------------LVTAFLYKL------------------------
n29_Tthe_PI4K    ITVCQKFQEIEKLPYAIIFYLKLVRQRRQKA-----------------------------
n73_Tthe_PI4K    ---------------------------------KGS--FNIEQNGFAS------------
n131_Tthe_PI4K   ------------MDFYISFIVYLVITR---------------------------------
n502_Tthe_PI4K   ------------LNFYMSELCYLYITR---------------------------------
n508_Tthe_PI4K   ------------LNFFMTQLCYLCIQR---------------------------------
n545_Tthe_PI4K   ---------------------------------NGNGMEHDLNNGFLS------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ---------------------------LVT------------------------------
n858_Tthe_PI4K   ---------------------------LVT------------------------------
GK310_Glam_PI3K  ---------------------------LT-------------------------------
GK311_Glam_PI3K  ---------------------------IT-------------------------------


29569_Tthe_PI4K  ---------LENYCRA-----------------------LQTSQHKICALRNAIALIRFL
13773_Tthe_PI4K  KKFLAKRKQGDNLFGDQIKQLKLAI--NSQSYFREINVLLSQLDVVTFIVKNNFFSVQEE
20618_Tthe_PI4K  --------------------SQLKIN--NLENEKQM---INLLSSLTCLIKNGPELVRPH
20619_Tthe_PI4K  --------------------SQLSYNKKRFENEKKI---INLLKGLVCLIKNDTEVVKPH
n8_Tthe_PI4K     --YFNKNKNR------ADEVL------------------KKTLREVYYKYKIKLQPQD--
n29_Tthe_PI4K    ----------------FDQVV------------------KEQSRKVFESTFKLFENHI--
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -------------------------------------------PSVYLEQFLASLSQQ--
n502_Tthe_PI4K   -------------------------------------------DSEMLKKFLVDMSSR--
n508_Tthe_PI4K   -------------------------------------------GSQSLEKFLVDKCAT--
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ---------G------ADEVI------------------KNILRKIYKEYKIALKPKDQ-
n858_Tthe_PI4K   ---------G------ADEVI------------------KNILREIFKQAKVKLEPNNP-
GK310_Glam_PI3K  --------CDEACCIVYEYAS------------------SQYGSQRLDL---ALRVTRP-
GK311_Glam_PI3K  --------TDMDLAL-AHKVI------------------EHYYRVAMKE---ALYLNKP-


29569_Tthe_PI4K  T----------------------PFLETFSSQFNQSAT----------------------
13773_Tthe_PI4K  LLQFEDIIDSFCTNIEN---FFNSLFKIQESYLKSDGL----------------------
20618_Tthe_PI4K  SQSIANILLNFLKDQKITNNMIPELLKTF-SQLSSLGD----------------------
20619_Tthe_PI4K  SMTIATILLKFLKDSTITNNMIPELLKAF-SQLSALGD----------------------
n8_Tthe_PI4K     -----------------------N----KTFILKIEGY----------------------
n29_Tthe_PI4K    -----------------------Q----KFNPFQIYNFCENFSKI-QYLGFENLESIDFY
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -----------------------N----LSFYLKMLWILQAYSDSCKLKSF-----KGWQ
n502_Tthe_PI4K   -----------------------S----INLYLLIYWSLDSFSESLKLDEA-----KKAE
n508_Tthe_PI4K   -----------------------S----ASFYFLVRSIVDAYSVNIKLDVD-----EQRN
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------TGSSIHRNQLK-------------------------------------
n737_Tthe_PI4K   -----------------------N----HQFILQVKGF----------------------
n858_Tthe_PI4K   -----------------------D----HQFILQIKGF----------------------
GK310_Glam_PI3K  ----------------------------YDLVIKQRGT----------------------
GK311_Glam_PI3K  ----------------------------HI--QKQLTA----------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    DISRKTHKAITALSYSYKPSAEQLGAQYITNLKLRYIAKSIEQVVVR-SYNYEEISSLQF
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -EHK--------------------------------------QICQQEFFLLLDTQRLHL
n502_Tthe_PI4K   -NE---------------------------------------------------------
n508_Tthe_PI4K   -LQ---------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ---------------------------------------L---MEILLDDAVDIDIQ---
20618_Tthe_PI4K  ---------------------------------------NTILL--YMDEIFPIFLQ---
20619_Tthe_PI4K  ---------------------------------------FQNLI--DMDEIFPIFLS---
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    NSKATLIDKRKQRMMNMLIQFQEIRNLNQSKSSLSEDHKY-ELI--SLENIVISFFKTFT
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   I------------------------QYQQKQK-LI--------------EM-------G-
n502_Tthe_PI4K   -------------------------RIKDLLK-TV--------------EN-------S-
n508_Tthe_PI4K   -------------------------KFK---E-DV--------------EK-------S-
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ---------------------NK-------YLIKAAC---WRIVRFILFVHDGSISYVAL
13773_Tthe_PI4K  ---------------EN----------QYQ----AVINLFIKICEFMSLLSNDILNF--T
20618_Tthe_PI4K  ---------------AMQDKSSTA---KRE----AAVKSLVDILKYTGFVVLPYYKY--P
20619_Tthe_PI4K  ---------------AMQDKSSTF---KRE----SAVKSLVEILKNTGFVVLPYYKY--P
n8_Tthe_PI4K     ---------------------RE-------YLSG--------------------------
n29_Tthe_PI4K    NNTEQQ-IQNGGSFEAETSINNRFTSTII-------SDLILPKFDLSGFLSQKYM-----
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -MVNSA-VNNDLLMQ---------------------------------------------
n502_Tthe_PI4K   -FINAS-MQSSL-IQ---------------------------------------------
n508_Tthe_PI4K   -YVNGISCRSCFYLK---------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   --------------------------------------EQLDLQKIYAFQKIPS------
n737_Tthe_PI4K   ---------------------RE-------YLAG--------------------------
n858_Tthe_PI4K   ---------------------RE-------YLTG--------------------------
GK310_Glam_PI3K  ---------------------SA-------YLVG--------------------------
GK311_Glam_PI3K  ---------------------SLF---NQEAI----------------------------


29569_Tthe_PI4K  VFLIFCFELL-FS--ER-SLLNQ--------EHERFL-HLLLAFLHVYRNR-EDA-----
13773_Tthe_PI4K  TFLDVLLNITLENKYSIFLQMLLKPNHLIRGMNIDIFLTKSE----LYFEKITPVIKA--
20618_Tthe_PI4K  SFLEIILSLM-KN--EVNVEMRQ--------QCMRLI-GCLGAIDYFYYKKVSDKVRNRL
20619_Tthe_PI4K  NFLEIVFSLM-KN--EVNTEMRY--------QCMRLI-GCVGAIDHFFYKKVIDKIKNHS
n8_Tthe_PI4K     ---------------HY-PMLSY--------DRVRTNLRIKKSLKVILDQK-QNA-----
n29_Tthe_PI4K    --------------------KNQ--------HTITKKLFQFHLKLI--QYIG--DQDQ-R
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ---------------------------------AQKENITE----E--ETQC--KFKR-E
n502_Tthe_PI4K   ------------------------------------ENKTP----SQ-VKESNERA---K
n508_Tthe_PI4K   ------------------------------------ENRPT----QEIINQANEKGARID
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   AFLEIDFP-------N-----------------------------------------F--
n737_Tthe_PI4K   ---------------NH-PMLNY--------DRVRTSLRGLDHLDVKLTEM-PIN-----
n858_Tthe_PI4K   ---------------NY-PMLSY--------DRVRINLRGHEHLDVRLTEI-PIK-----
GK310_Glam_PI3K  ---------------MD-YLINY--------DSVRVCLKKAEPLYVTLANR-KEF-----
GK311_Glam_PI3K  ------------------AVSNY--------AAIT-------------------------


29569_Tthe_PI4K  ---------------------------------LFKYSQQVATRIIMKL--IKKINYNS-
13773_Tthe_PI4K  LQEITQEGVDFFQDYVL-KALEDIFKGNKPQKFEEIISDEQKLKENELK--IFLEGIKL-
20618_Tthe_PI4K  TASPSQDNRQ-----------------------LINDIIKVSLKKKFKY--FKKLSAAK-
20619_Tthe_PI4K  ITSSFADNRI-----------------------LVNYIVTKSFRKRFKF--MKKLIKYQ-
n8_Tthe_PI4K     -----------------------------------VQNQKLFPPEFERL--VITINFNK-
n29_Tthe_PI4K    KRALNDLSRGLLLVFQEHEYNDI-------------------------------------
n73_Tthe_PI4K    -------TINFFDDLIN-VSEQL-------------------------------------
n131_Tthe_PI4K   YFYALK-TN-KLLNLQNKTYLIL-------------------------------------
n502_Tthe_PI4K   YNNSI--KT-FIKNMVN-ISLTL-------------------------------------
n508_Tthe_PI4K   YIKLN--DS-FLGNMVN-YSLLL-------------------------------------
n545_Tthe_PI4K   -------TIQFFNDLMD-ISDNL-------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------------------------NQQADQFPPIYERK--QS-------
n858_Tthe_PI4K   -----------------------------------SRKADLFPPTIMRK--KT-------
GK310_Glam_PI3K  ---------------------------------EKAMSDTLLGHTFENI--IFNFNFKL-
GK311_Glam_PI3K  ---------------------------------------------VQNYIPCMQFYDCEQ


29569_Tthe_PI4K  ----SGDSSSLSS-------------------------------------------SRK-
13773_Tthe_PI4K  ----IFKL--CSQSSRYTIRYIEKAISGILNGVKSSEENILNKQDSL---F---RESRT-
20618_Tthe_PI4K  ----QQESSS--------------------------------------------------
20619_Tthe_PI4K  ----QTNQSS--------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ----------------------------------------------IIKKIVNKLSL---
n73_Tthe_PI4K    ----------------------------------------------K---D---AD----
n131_Tthe_PI4K   ----------------------------------------------S---KINKSNP---
n502_Tthe_PI4K   ----------------------------------------------K---KHEQ-DE---
n508_Tthe_PI4K   ----------------------------------------------K---GIEK-PD---
n545_Tthe_PI4K   ----------------------------------------------K---F---SD----
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ----FLQD--CNP-------------------------------------------TKST
GK311_Glam_PI3K  VLAKFTAD--QEA-------------------------------------------GAFS


29569_Tthe_PI4K  KINIQTSSKSSSNSTNNS-----DLDQSHQ-------MKDYWF----------L------
13773_Tthe_PI4K  QQIFQFALDISSESTNEF-----ILQIISQQSQFFQKYENQLLTYVKSKWNLIGQKY---
20618_Tthe_PI4K  ----------------IL-----TKQLHQY-------YEDII-----------L-L----
20619_Tthe_PI4K  ----------------EL-----PFQLHKY-------YEDVIL----------L-F----
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    -----------------NLIHCTYEEKI--------------------------------
n73_Tthe_PI4K    ----------------PK-----DIALRTYIKQ---------------------------
n131_Tthe_PI4K   -----------------RKVQR-----Q--------------------------------
n502_Tthe_PI4K   -----------------RK-----------------------------------------
n508_Tthe_PI4K   -----------------QK-----------------------------------------
n545_Tthe_PI4K   ----------------PK-----IVSLRYELQK---------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  LIHAGTSSAS------EP-----SVGTPPL-------FDDQIL----------GTF----
GK311_Glam_PI3K  RLAVALKTAT------E----------KPL-------SDVDLF----------GLKSATS


29569_Tthe_PI4K  -----NYNYHKKELKQIQEQPLIDEQVI-LILSYL-KNLLQEPQDFTQIKISKS------
13773_Tthe_PI4K  ------LMLAKD------------------------------------------------
20618_Tthe_PI4K  -----ENFKQKKMY---------------LKLSNIQAEIDYNLEGANSLNIY--------
20619_Tthe_PI4K  -----ENFKQKKML---------------LNLASIKKSLNNQPNKFDPLQIYGSSAFLQL
n8_Tthe_PI4K     -----------SDNKHQRFNK---------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------TFFLDL
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------GTP---
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ----------------------------------------------ETLVLY--------
n737_Tthe_PI4K   ------------EMEQGIFT----------------------------------------
n858_Tthe_PI4K   ------------DVANSKYQ----------------------------------------
GK310_Glam_PI3K  -----GSIVHKKDVMNLEFQPLLRSPAK-SIAS---RETCNSPASSIDLMRSSN-----C
GK311_Glam_PI3K  TYTNAETLSHLRNIIARSFNKYQADPTPTSSQN---DDTSPSQDSSYTLTHNVR-----A


29569_Tthe_PI4K  --MQEELKS-KNLNEIQLKKEKEKLSLIHLQKIKEKK-----------------NAIYL-
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------QQP-QKKDNRF-RD-QNMIEKLYSKQEIDEE-----------------IKMLL-
20619_Tthe_PI4K  QQMLDQQQA-ISIENEILNDETRNTERIHLTQESDDE-----------------IREML-
n8_Tthe_PI4K     -------------QEKTIEEIQNLLKLVQNDILFKQGGKIKQLYLSNNYKIIDNTNQII-
n29_Tthe_PI4K    IQKFNQ-NF-FQIEKDYSEDSQNKK------QQKRNH-----------------IKQTL-
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------QEPEYIIDNDLSSKEINNSQ----------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  TKQADDAEA-ERLESTPFESLTPVIPKIHAESAAKGIGR---------------ANSFL-
GK311_Glam_PI3K  ATSIDEIKL-DQFNPTDYA---------------------------------------LA


29569_Tthe_PI4K  ---QLLNLPK------LS------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ---QSPTVIS------LTDE----------------------------------------
20619_Tthe_PI4K  ---QAPTVIQ------LNDQ----------------------------------------
n8_Tthe_PI4K     ---FQDQF---------NINWEDYQQIPA---LLWYPP--Q-------------------
n29_Tthe_PI4K    ---QILPLIRECLKIFL----------------DRKQFTQVTSNSNQLQTASAAMTEFWI
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------PIDWSNYYEVPI---LLWYPW--V-------------------
n858_Tthe_PI4K   -----------------KVNWKKFHGVSI---LLWYPW--I-------------------
GK310_Glam_PI3K  ---KSPTLAP------LRTNSEENASI-CAESYSWDPK-LQPLPLPPGNRFYDDYV----
GK311_Glam_PI3K  LNYKISSKCK------VRDQNEHILSA-IAPQYDADPSTLVPDNASAGKLAKLCDV----


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------DYYSK---ITIKALL---------
20619_Tthe_PI4K  ------------------------------------DYYTR---TTIKAVL---------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    FIVLNKSIIYEKDYLKESDFENINMIALLSPNFLEGEQLSFVASKIIQLINQSK--IYVK
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------EYYSFLSSSTFDLLIQKRCAEYAK
GK311_Glam_PI3K  ------------------------------------LFTHQLRSQDKDLIWKYR------


29569_Tthe_PI4K  ------------------------------------------DN-KKILAKNSHSMNALV
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ----------------------------------KILC-DQSLNEHHSLAVQTLS--CII
20619_Tthe_PI4K  ----------------------------------KILY-DQSLNEHHELAIKTLN--CIV
n8_Tthe_PI4K     ---------------KLPRYVPQQNI--ND------------------------------
n29_Tthe_PI4K    DIKQRY------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ---------------DFPEKDT--------------------------------------
n858_Tthe_PI4K   ---------------EFPEEKD--------------------------------------
GK310_Glam_PI3K  DPLSFYT-RYCGSVKGVVRRCPLRFAPLTQLMKRKIVPDKQSMNQSHFLPSKKHS-TATV
GK311_Glam_PI3K  ----YYMRKYPRGLIKVISSIPQSYR--NVLIRQRSVKDKGQDSGQNFGDSIDES-TNQ-


29569_Tthe_PI4K  KIKQELLVDCLGLIGPV-----QQHD--FQENYQDILPINLTPADLKEK-----------
13773_Tthe_PI4K  ------NISLLKLTIPLLQSIIQSFNR--KE-----------------KE-ESLLILIQN
20618_Tthe_PI4K  GVLQTRTKNFLDLLIPIFIKIVRQDMLRDRE-----------------NILQLIQKIILN
20619_Tthe_PI4K  NLLKSRTKNFLDLLIPVLCKVLEQDNI--RE-----------------DILNIILVIIEN
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  RS-----------------------------------PEELTIVDIRT------------
GK311_Glam_PI3K  -------------------------------------DLRHIVGELKT------------


29569_Tthe_PI4K  ---------IKSFL---------------------------NV------------N----
13773_Tthe_PI4K  LPVINIERKEDTFLEIELKLNWLIMSSIEGLVIEKNYSDYVEKLIEVSLKVEKSLFIHEQ
20618_Tthe_PI4K  CGRYYDQEYLDPIL---------------------------NVFLEFGQDPQYYKI----
20619_Tthe_PI4K  CGVYYKQNYLDQLL---------------------------NMFLEYSQDIRYSLI----
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ---------LDEEL---------------------------SV------------R----
GK311_Glam_PI3K  ---------LLYT-----------------------------------------------


29569_Tthe_PI4K  -------IFNTDIPLVSLCICKDFLS----------------------------------
13773_Tthe_PI4K  GFNLLGFYLKCINNADFFV--KRGLRDKVNSV-------------RSKYFPMKVKELKRD
20618_Tthe_PI4K  -------CFSILENLIEFQ--KRNLRHYIEPI-------------IRL------------
20619_Tthe_PI4K  -------CLKILKVVVSFH--KRNIYYKIEPI-------------VQK------------
n8_Tthe_PI4K     --------------LIEYQ--KQNLQKYKESQETFNEHKKKYLKLYKQ------------
n29_Tthe_PI4K    -----------------------------------------------------KESFKSG
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  -------LLDVSLPLSSFP--KENISKFKS----------TKWGT-RP------------
GK311_Glam_PI3K  ----------WNDP------------AI--------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  SKQEIDFKSILGC---------------------------------------------MI
20618_Tthe_PI4K  ----------------------------------------------------------IN
20619_Tthe_PI4K  ----------------------------------------------------------VN
n8_Tthe_PI4K     ----------------------------------------------------------TN
n29_Tthe_PI4K    SKQQIN--EMLHCLIQEEIMANKIKLLKTHMYQISQ-----FYKPSIY-ESLFFYLREVG
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------FKLQQHSQQIYQ-----QHYQNIY-LSKA-------
n502_Tthe_PI4K   ------------------------DKLKMYMKRANKWLK-NLREQNPNNEFFQ-------
n508_Tthe_PI4K   ------------------------AKLKEFMDNENFWIINTLRKVNTD-TQYE-------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ----------------------------------------------------------YN
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  NMIKLAGQIELLEILFPVIRESLE---EPYHTKIITFIQQFI-KENFMTQTVNKQLYFME
20618_Tthe_PI4K  NVIYKPQIDESTVLQVIKIYTLLAELLDSNLHL---------------------------
20619_Tthe_PI4K  NLIKKAHVDEEFTLRVIQIYKNLAEYLNPHLHL---------------------------
n8_Tthe_PI4K     GFLFTTQQD----RYFSM------------------------------------------
n29_Tthe_PI4K    LNAKTFHVMEPLVKQISEEQINLFSKLQQILHLFFQINSYMILFRK--IKLTSVN-----
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -------------------------------GILIPFSKQ--------------------
n502_Tthe_PI4K   -------------------------------GIFIPFRED--------------------
n508_Tthe_PI4K   -------------------------------GITIPFRRP--------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  VIDYAMHIDPRYTARVEA------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  WALDQYKDKDLDRSLLECIRYEIIQKVLLHLIENAKEEANVKFMKQENMKEVLRWVQELI
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  QVFNIFESLYKALSLDKIKDDVHKKLYPDTTQGNELTKSLIKIAFEYRKKGFERADDIKN
20618_Tthe_PI4K  -----------------IVPFLCNYISKDTSQTKTKVK----------------------
20619_Tthe_PI4K  -----------------IIPFLCQLITQNAQLVNMQVK----------------------
n8_Tthe_PI4K     ----------------------------YDQQTLEK------------------------
n29_Tthe_PI4K    -----------------------------VKEEIL-------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -----------------------------QGEVF--------------------------
n502_Tthe_PI4K   -----------------------------YNQQL--------------------------
n508_Tthe_PI4K   -----------------------------LKSKY--------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ----------------------------IDQKALEE------------------------
GK310_Glam_PI3K  -----------------------------------DWL----------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ---------------------------ANE---------ASKSQDDMEE--RSNMLNASF
13773_Tthe_PI4K  NVQNNPDLIGIDSHSILRLFSCAV------YNCLSQIITK-----TQ----NKENILNQF
20618_Tthe_PI4K  -------------SEIINLFNCFA------NSCCSTVQFL-----SL----IVDSILIN-
20619_Tthe_PI4K  -------------TEIIQLFQYLC------FYCSSSIQYI-----SL----IVDSILQN-
n8_Tthe_PI4K     -----------------------SNYSSIQSTVQD----TNTQQDDLLR--FSTKISQE-
n29_Tthe_PI4K    ----------------AKDFSY-----LLE-ASCSADNN-------ISE--F--------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   -----------------------YNRKIITLKLDF----TDEQEQQIRNNVPPLPLSQL-
GK310_Glam_PI3K  -------------AELLRI-LCFSD------QKLS----TTDSSGPMNR--LSTPVHRA-
GK311_Glam_PI3K  ---------------------D---------QLLL----LLSQEYSLYN--LNTNVIRE-


29569_Tthe_PI4K  SSRGINENTNGNATNLDHSIIHQQKQ----------------------------------
13773_Tthe_PI4K  --------------------LFQQKNDHLWDLLIDGTQKEFNFEIETNFEERSYARTRNI
20618_Tthe_PI4K  -------LEQSKDA----------------------------------------------
20619_Tthe_PI4K  -------IQTNKFQ----------------------------------------------
n8_Tthe_PI4K     -------YSAGKDV----------------------------------------------
n29_Tthe_PI4K    SLQMIQE----------------------------------------------------Y
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   -------NGSGDNE----------------------------------------------
GK310_Glam_PI3K  -------ERRGSDA----------------------------------------------
GK311_Glam_PI3K  -------YAINKLNQFADSV----------------------------------------


29569_Tthe_PI4K  -----------QFNLMQWLAELIMKMKKQDETIKIIEGCMELMANSDLGEFLTPYIIFKY
13773_Tthe_PI4K  FSRIPKFDTKEI----------------------LCKKYLN------------ETVLC--
20618_Tthe_PI4K  ----------------KF-----------------INECMN------------TVVVF--
20619_Tthe_PI4K  ----------------PL----------------MTNSIMD------------TIVVF--
n8_Tthe_PI4K     ----------------KLINQV---QN---------------------------------
n29_Tthe_PI4K    IKWFPQ-------------------------------LVFN------------PSVLM--
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ----------------EARKRA---KS---------------------------------
GK310_Glam_PI3K  ----------------QFNGMI---QNL------------------------------KY
GK311_Glam_PI3K  --------------LLQFLLELTFKIDL------------------------------DE


29569_Tthe_PI4K  INST-----------ENSHLEIIPVINK--------------------------------
13773_Tthe_PI4K  TFNK-----------TSASQAFLPSFAN-------ELI---------------------S
20618_Tthe_PI4K  IYIH-----------KNQFLVYLTKLNY-------VVK---------------------Q
20619_Tthe_PI4K  IYKY-----------RNDFQAYLPKINQ-------TVK---------------------S
n8_Tthe_PI4K     ----------------------------VFNQQQQQIIRI-IISQMNIMK-MNIQMKIKL
n29_Tthe_PI4K    TFSECLTALYQKCSYEYDSKSSLLQGKH-------LI---------------------YS
n73_Tthe_PI4K    -INE-----------QLPSAVYIPFFSQ-------QIR----------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -INQ-----------QLPAAVYVPFFAN-------NYR----------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------PNPNQVV-QKRMMHQRMQ
n858_Tthe_PI4K   ----------------------------EFQEQPEPIIYEEIPHPINICLQKFIQKEKKK
GK310_Glam_PI3K  ILAD-----------IDQLLADLG-ASPIFEEAFYSVEQS-ILSHDNSLT----------
GK311_Glam_PI3K  SLCI-----------VDLFNY---------KELYQSIEDQ-MIDQQETLA----------


29569_Tthe_PI4K  ----------------------------------------IL------------------
13773_Tthe_PI4K  KNSEHDIYED-----------------EEDESENIIQETKKYMQQQQNLFFGDQTGENLE
20618_Tthe_PI4K  KNIQHIAYQKCVDIFLNNGNLDDVSSQIEPEFQKIVGEIKTDQP-P--------------
20619_Tthe_PI4K  QNIHHNIYSKCIEIFLNYGNLVDVSSQIESD--IALLECKRIQEQP--------------
n8_Tthe_PI4K     LKKDRGIFNKLIKIFINQKKFSVRQIQIDSQ--KD-A-NKFL------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------DLKLNKK--KQ---SQN-------------------
n858_Tthe_PI4K   ------------------------QYKLDGT--LN-FKNEY-------------------
GK310_Glam_PI3K  ---------------------------------KS-LDCKSSEE----------------
GK311_Glam_PI3K  ---------------------------------RE-K-KKR-------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  MDLINRHPCMPTVLTNIDKMVQQFPLTEAMPQWMTNLLEEVKKDSCSLGQKIFIIKIVLN
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ----------------------------------INLPTDIKKM----------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -------------------------------------------H----------------
n502_Tthe_PI4K   -------------------------------------------N----------------
n508_Tthe_PI4K   -------------------------------------------S----------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -------------------------------------------EEGHHNH--KLIITKTL
13773_Tthe_PI4K  KPLLFEKYSQQWFDVLVDYAKLNDNGSKFFHYFLRDVTTTLIDWCSKKPN--LVT-----
20618_Tthe_PI4K  -------------------------------------------QQQELFN--SLL-----
20619_Tthe_PI4K  -------------------------------------------YTLEPQD--SLT-----
n8_Tthe_PI4K     -------------------------------------------GEGQQND--LLL-----
n29_Tthe_PI4K    -------------------------------------------------G--GTL-----
n73_Tthe_PI4K    -------------------------------------------------N--YVV-----
n131_Tthe_PI4K   -------------------------------------------------S--NLV-----
n502_Tthe_PI4K   -------------------------------------------------S--TFI-----
n508_Tthe_PI4K   -------------------------------------------------S--NLV-----
n545_Tthe_PI4K   -------------------------------------------------N--HVV-----
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  -------------------------------------------FQRGPQKLPEDT-----
GK311_Glam_PI3K  -------------------------------------------LETAEQD-LLNI-----


29569_Tthe_PI4K  INLDTWFRQELKQEKQQNY--------------------DPFRP----------------
13773_Tthe_PI4K  ---RRIASDKKQNLCQ-VL--------------------AHKEK----------------
20618_Tthe_PI4K  ---RKIDSDKLAQVFS-TS--------------------SNTSK----------------
20619_Tthe_PI4K  ---RPIKTDKILKLFD-TH--------------------SNQSK----------------
n8_Tthe_PI4K     ---RVIKKERMKELVE-KR--------------------RNLSQ----------------
n29_Tthe_PI4K    ---VILM----NLLQK-LMLKGHFIDHNFLKVLIQHIVKQEGSISSKIDFGYRFLKYESI
n73_Tthe_PI4K    ---LNIV----PTECR-VF--------------------S--------------------
n131_Tthe_PI4K   ---VNIV----EDEFM-C------------------------------------------
n502_Tthe_PI4K   ---VRIV----HEEVT-C------------------------------------------
n508_Tthe_PI4K   ---VKII----SDEVT-C------------------------------------------
n545_Tthe_PI4K   ---LNIV----TEECK-VF--------------------S--------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----LSEILT-QNVQ-PV--------------------QNGSS----------------
n858_Tthe_PI4K   -----LDSIPMKDFVS-VE--------------------ENYNK----------------
GK310_Glam_PI3K  ---TPLKERVSLDLHL-AD--------------------LTVPP----------------
GK311_Glam_PI3K  ---TPIIET---------------------------------------------------


29569_Tthe_PI4K  -------------------------QSIMHSESPKNRFIR--NFA---------------
13773_Tthe_PI4K  -------------------------EIF-------KQNIQILKNLLDLWKECIYVDENQL
20618_Tthe_PI4K  -------------------------EDW-------NQWIR--KTS---------------
20619_Tthe_PI4K  -------------------------EDW-------IQWMR--KSS---------------
n8_Tthe_PI4K     -------------------------QQIF-SEVPTNLY----------------------
n29_Tthe_PI4K    NFRGDRNQILENILACNPFLWLINQE----------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ----------------------------I-NMKNTNLY----------------------
n858_Tthe_PI4K   ----------------------------I-NQ--KKLT----------------------
GK310_Glam_PI3K  -------------------------PPIT-DTA---------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -----------------------FIKVYCKT-----------------------------
13773_Tthe_PI4K  TKMLLLEDKEDKEKSQLWNLNSILILDACIQLRIPILSNYEAFSRAQTVEEKFAFFLNIS
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ---------EFEQRIKSCNLNMF-------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------LVEMSEHKGAI----QLLEQELEQQDIQLL
13773_Tthe_PI4K  EKDRLKRLLLFQQHSKRQYCKAASAVCGGLLSMMHEYGGQFEGKRKIYEQEIVNNSVNII
20618_Tthe_PI4K  ------------------------------------------------------VE--LL
20619_Tthe_PI4K  ------------------------------------------------------IE--ML
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  N--LTDAQEIKNIKKL--------------R---TH----------------YIYQLYNI
13773_Tthe_PI4K  N--KTDKT-------S--------------KERFPI----------------IVACITQY
20618_Tthe_PI4K  NKSP----------NF--------------V---LT----------------HCKELAEI
20619_Tthe_PI4K  KESP----------NL--------------I---LS----------------ACHQLAEV
n8_Tthe_PI4K     ------SGECDWIFKV--------------K---IK----------------GIENLYRI
n29_Tthe_PI4K    ---------------VVDRNLLELEKIKNNQPPANFRVIIENIEKSIHNEIELEFQMEDK
n73_Tthe_PI4K    ---------------T--------------KERSPY------------------------
n131_Tthe_PI4K   ---------------------------FNTKKRAPYKIVFETVDM---------------
n502_Tthe_PI4K   ---------------------------FNTKMRVPYRVAIETIDI---------------
n508_Tthe_PI4K   ---------------------------FNTRTRVPYRVAIETIDI---------------
n545_Tthe_PI4K   ---------------T--------------KERSPF------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------SGECDCLFKV--------------R---IC----------------GLENVFKI
n858_Tthe_PI4K   ------SGECDCLFRI--------------R---IC----------------SIENVFKI
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  YKEVNE------------------------------------------------------
13773_Tthe_PI4K  YPDF--------------------------------------------------------
20618_Tthe_PI4K  YEELQA------------------------------------------------------
20619_Tthe_PI4K  YQELQV------------------------------------------------------
n8_Tthe_PI4K     FEQANV------------------------------------------------------
n29_Tthe_PI4K    VEEERIIKENVNLQTIVEQRMKEIANYC-----------------------------FNL
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------DEMKEHMYYF-----------------------------EKL
n502_Tthe_PI4K   ------------------NELKQVKKKVVSETDLDDVGIIGDGPEFSENNNDQAETSQ--
n508_Tthe_PI4K   ------------------EELKINGRT------------------NRE-SNSDLQATQLL
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   LQAVDP------------------------------------------------------
n858_Tthe_PI4K   LKSVSP------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -------------------------DYKNI---DVVEMMRKL--DLD------ETEIKKY
13773_Tthe_PI4K  --------------------------LNNIKIITYCQDYIHQKSKMDRAYILQSILIFLK
20618_Tthe_PI4K  -------------------------ELFNI---SFVCVWSQL------------------
20619_Tthe_PI4K  -------------------------ELNNI---SFSSVWAEL------------------
n8_Tthe_PI4K     -------------------------KD---------------------------------
n29_Tthe_PI4K    NIIDTICSNSFKQIKFILK-NP--L-----------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   NRKNSVESDE---MEELQQ-VKADKID---------------------------------
n502_Tthe_PI4K   ------------------QSVIKQNE----------------------------------
n508_Tthe_PI4K   NQQNSKIKQL---VARLAQAVKAQTPS---------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -------------------------QW---------------------------------
n858_Tthe_PI4K   -------------------------EL---------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  QDINLK-QKN-DGL---------------------------------------------C
13773_Tthe_PI4K  KKL---------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     --DNYR-ATY-NGI---------------------------------------------L
n29_Tthe_PI4K    ------V-KV-RLLPQIFEI-I---------EKSSNSSEMKRDLQETKDLIANDMKTMVA
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   --EVDKE-KF-RGLAKWAEI-M---------KKEEQSKQ--------KKSIIQKLL----
n502_Tthe_PI4K   --STDKINKYGRTFSIWACEAENQEIKLNEIRNSQMKIQ--------KKGELVNLL----
n508_Tthe_PI4K   --QNNKQNKYNDNLVVLLEQ-E---------KKKEEEEQ--------KKEEMLKTQ----
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   --PGLK-ATY-NGF---------------------------------------------T
n858_Tthe_PI4K   EDKTKE-AVY-NGI---------------------------------------------M
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  PEIYEDIVDRNFRDEE--SQ--QKLI----------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  --------------KD--HN--KTFIKEQFSKAINP-------ENNVPINILQTILNLTE
20619_Tthe_PI4K  --------------KQ--KE--KEYIINQLDPALNFQHRDGDRAQKVPLNLLQLLLNLAE
n8_Tthe_PI4K     PPVYITKFGEWLKAKE--HE--EKIAIPQR--------IDGNPKPALRLSKVIPQRKDER
n29_Tthe_PI4K    ------SFRTVMMKKP--QL--KNIILS--------QLLDISRIYLSPTLLKYLLYRFIP
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   QPAYVTLVRHGVDDKEDKHNKEEKDKKEQK--------NKQNKDIQLQQEQ---QKQRK-
n858_Tthe_PI4K   QPSYITKSKQ-EDI--NKHQKS--RKQVQK--------KDKKKEINLKLCK---IRKEK-
GK310_Glam_PI3K  ------------------------------------------DEISFK------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ---------DKRENMKEDIHKICTSFRGV---VQN-------------------------
20618_Tthe_PI4K  FMQHDKEGIPIENTILGDLAERCLAYAKALYFREN-------------------------
20619_Tthe_PI4K  FMQHDKGGLPIKSSKLAELAQRCSAYAKSLYYRES-------------------------
n8_Tthe_PI4K     FNAHHKEEHSAAPNSQIDVSRRQGQMQESFQHSQMMSESGQSQSFFKFATDHGDKGCSYF
n29_Tthe_PI4K    FMH-SLQSSYFDSTLFYTLGELLSYIVHQINNQER-------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -------------------------SNSSTNSNQQ-------------------------
n737_Tthe_PI4K   --------------------------------------DQVTPKLNTRIVNHGIKGVEFM
n858_Tthe_PI4K   --------------------------------------LLKDAQMDTSITNHGIDGVAFM
GK310_Glam_PI3K  ---RQCKRTSV----------------------------KDTSQVDPAESL-----LVSS
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     QQLCQKYDINFAPYLIQV----------QVKLMYGNRALAVKKETQKIPFSRSPRWDEWI
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   KQIQGYYGMNLVPFSISI----------EAIIMNGSTCIK-SVETKRVPYGNTCKFNQWI
n858_Tthe_PI4K   GGLEKKFGLNCTPYLVSL----------KVMLFHGSNCLR-TVETKKQPFCKSIRFNEWV
GK310_Glam_PI3K  KASQDILKINTTYVFTTVAQIHVGTEPISDKAFAGYAALE-FSEVKKAEVVCKLHYDTTL
GK311_Glam_PI3K  ---------------------------------------------KSLPFKGTK------


29569_Tthe_PI4K  ---NLLSKSIPDFA-----------------------------SQNQDFAFQKYLRSICW
13773_Tthe_PI4K  -------VAEDENVENQEKFLSL-FVFLSSPQI-------LNSFDD---AIQ--------
20618_Tthe_PI4K  -------EFETANIQIIESLISL-YTNLGQREA-------AKGLLQ--N-VQQQL-----
20619_Tthe_PI4K  -------EFEKQGVETFETLEAL-YKQLGQKES-------AQGLVQ--Y-MQKYTKYQ--
n8_Tthe_PI4K     KFPLIKISQLPLESRICFDIIVYSVTG---------------------------------
n29_Tthe_PI4K    ----------ESNDDIFEVRKNI-YKGLVTFEAKEFFSEAYQTLIQ--Q-QQNNEQYW--
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -------SLTGG------------------------------------------------
n737_Tthe_PI4K   SFNNIKVSQLPLESRLCFNLKAYAQNS---------------------------------
n858_Tthe_PI4K   TFDNLKISQIPLEARICMNIILHSDDQ---------------------------------
GK310_Glam_PI3K  SFKNFLTKFLPFGAQIVFTVYAVNKKSLGRLIQ-------AANVTNQLF-SQSYIKLLNE
GK311_Glam_PI3K  -----------------------------------------KN-----------------


29569_Tthe_PI4K  GFQKILNYEKNN------------------------------------------------
13773_Tthe_PI4K  ---------------------LMRISISILKQ-----------------KYERHYQEKFA
20618_Tthe_PI4K  ----------------------R---LDVNE-----------------SWYERLHQWEYA
20619_Tthe_PI4K  -----FRSQNNISDQ--IMTNQT---IDGNN-----------------SKSIQ---IQK-
n8_Tthe_PI4K     ---------------------------------LDSQIIGSTNFYIFDQFCK----FTQ-
n29_Tthe_PI4K    -----FSQLPNIISFYQVRKKCL---F-----KMHRMLLGFLNE----NMQVHI---AK-
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ---------------------------------NDYQIIGSSTLPIFNSQEL----FQQ-
n858_Tthe_PI4K   ---------------------------------NEHQIIGSTSFSLFDQDDK----YRQ-
GK310_Glam_PI3K  KQ-SSILQSSNQSVS--TMFIET---YDGLLADSSTLILGSVSVPFFDSSGA----LSR-
GK311_Glam_PI3K  -----------ALQS--KSILSG---M---------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  TAYYTIVYNLYDYLINQESDLKDKNQINESEEMNQFKSQVKSCILCGLTSQHNTIRFNSS
20618_Tthe_PI4K  L---------DDYRVRQ-------------------------------------------
20619_Tthe_PI4K  -------------QLAN-------------------------------------------
n8_Tthe_PI4K     -------------GISP-------------------------------------------
n29_Tthe_PI4K    -------------SLKA-------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -------------GLNA-------------------------------------------
n858_Tthe_PI4K   -------------GLNA-------------------------------------------
GK310_Glam_PI3K  -------------RVYE-------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  IFQYKIQINIKNRENTFKFLDRETNDSK---------------------------TPY--
20618_Tthe_PI4K  -------LNIPE--Q--------------------------SFFVPKMRC-LNALSDW--
20619_Tthe_PI4K  -------LKLSD--L--------------------------AHFKIKVQQ-LEQYFEW--
n8_Tthe_PI4K     -------LNIWP--FYASDDRLACAGQYYGLTQPLSDENK------RDQR-DHNKWEEFK
n29_Tthe_PI4K    -------SIIAN--I--------------------------LHLNFKIDKSMIEFVPL--
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------KS-SKFFIQE--
n737_Tthe_PI4K   -------INVWP--FYRVHGRLSCMNEYWGCFTKL---RM------HEQK-DEKKIKEFI
n858_Tthe_PI4K   -------LNVWP--IQ---NRLCCMSQYWGLTDKS---LK------PKQA-NEKEMQDFI
GK310_Glam_PI3K  -------VPLWP--GTDASDVLSM-LLFRPY----TRGAMRISFEFPIKS-TEKVIK---
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  --SFDNMFQQLKSAIQK-------------------------------------------
13773_Tthe_PI4K  -ERLL--YLIQEIYQPEQER---------------------LWLLSAVPLIMCLSKRTSD
20618_Tthe_PI4K  -EQLIKNTQEENNPE--HRKQ---------------------VMHLAANAA---------
20619_Tthe_PI4K  -EKILTLMKEEEDYE--VKKQ---------------------VMDVAAKAA---------
n8_Tthe_PI4K     AREYSRLFIELDTFQKH-------------------------------------------
n29_Tthe_PI4K    -----------------------------------------------ENIC---------
n73_Tthe_PI4K    -------YICVEIYSPELEEAHELEE-------KQQKNNSQV------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -------YICLELYRSEE--PSKVDQNSPIIYTQERLKNGDV------------------
n679_Tthe_PI4K   -VDFSECVVTSDFD----------------------------------------------
n737_Tthe_PI4K   SQNYCRLFIQLDKFVEP-------------------------------------------
n858_Tthe_PI4K   SKNFTRVFVQLEKFNEP-------------------------------------------
GK310_Glam_PI3K  SLKFSPMVISTDPYKPPTEET---------------------LVMASSNVS---------
GK311_Glam_PI3K  SASPA-EFFDLRGSKDPIVDP---------------------KTSKTSIAS---------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  YDKNLFDEQLSKLAQFYDWDFRDSHNMRLYNSSQPLTPLYTLSQVNYKDSQGFAIPAPRR
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  MYNITGVSQMP-----------IQEGVRATVYSQSQDNSQGEMVIPSQDQASQMNQLEEK
20618_Tthe_PI4K  ---------MNLGNWELLENFCDN------------------------------------
20619_Tthe_PI4K  ---------MNLGKWEELEQFAEN------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ---------LCLKSW------------------------------------------IEL
n73_Tthe_PI4K    -------RRIPDW--KRQYALSKAQTV----------------YSHNNTQQSLRSGYQSE
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -------RY--KW--SYDERL--SQPL----------------TVNNQEYQSVVKDIETG
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ---------IPSG--QNSRSSSKTRS----------------------------------
GK311_Glam_PI3K  ---------IPVA--GNTFSSSSKLS----------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  RQIYQDQMKRLVNPSQQISSSFSSSNRNPYTFNQSQLFFDNKMSSISEENEDDENEEGEE
20618_Tthe_PI4K  ---------------------------------------------LPEENSQDKQ-----
20619_Tthe_PI4K  ---------------------------------------------LSDENTNDKS-----
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    LQLQKEFCQRFGS---------------------------------PDQNKL-QN-----
n73_Tthe_PI4K    RPPSKSAFQ---------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   NKPNQNTKKNIGNSSDFLSTNAALLDRKSESDDQPQVIMQSLKSEVG---------NPET
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ---------------------------------------------ASNKRSTSRS-----
GK311_Glam_PI3K  ---------------------------------------------I--------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  KKIDLFGTDIQREKKNNNLSKFFASHLFDFSQVNKNSTNK-IRYQDSKEGKTLTNTVDIK
20618_Tthe_PI4K  ---------------------FWQAAI---------SISK-GQYEEAK------------
20619_Tthe_PI4K  ---------------------FWLAAV---------CLKS-KNYEKSK------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ---------------------YYYR-----------SLKF-GLYHFAR------------
n73_Tthe_PI4K    ------------------------------------------------DVYM--QTIEKN
n131_Tthe_PI4K   ------------------------------------NVQK-NDNIEV-------------
n502_Tthe_PI4K   ------------------------------------NQDEELTS----------------
n508_Tthe_PI4K   ------------------------------------GIKY--------------------
n545_Tthe_PI4K   KKTL--------------------------------------------DIRTQSKTLDVT
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ---------------------YSTR-------------GR-GASRR--------------
GK311_Glam_PI3K  -----------------------------------------KSFTH--------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  KRQQQLFFENQN-RMRKQQLQT-IRKYK-------I--GELPDIGILYKDIIDPLMALSF
20618_Tthe_PI4K  --------------------------NL-------ISESI--------------------
20619_Tthe_PI4K  --------------------------VY-------IHESI--------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    --------------------------NLNWYADKSGGQKI--------------------
n73_Tthe_PI4K    Q-----------QRYSRMSISNQHQFEL-------IEMSE--------------------
n131_Tthe_PI4K   -----------------------------------EHYTI--------------------
n502_Tthe_PI4K   ---------------------------------------V--------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   KPNSQSIAQNGNSNNNKLTIG-SSRHRS-------FGESI--------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------RNAC--------------------
GK311_Glam_PI3K  ------------------------------------H-----------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  IDETLAGQLFQLLLHSMFMKEESADRQQKLKDILSNILAKSIVHDFNFVSTIHKTMIMLT
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  --LKYAF--------S---------LQLV--NAKCCYDSK-------FSVLVKIQ-VLLN
13773_Tthe_PI4K  K--EGELFDSNIIKQS---------GLLS--H---SY----------YTSILLLEESLFS
20618_Tthe_PI4K  NKLDSQV--------S---------GLLL--E---SYSRA-------YESILRLQ-QLFE
20619_Tthe_PI4K  QKLDNKV--------S---------GLVF--E---SYNRA-------FESILRLQ-QLFE
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    NKIKDKM--------K---------LL-LNVC---KY-----------FQTDKLN-EIFE
n73_Tthe_PI4K    K--QDKQNGIACA----------------------------------YEP----------
n131_Tthe_PI4K   HKLDTLV--------LQ-----VQQGT--LRN---SS-----------P--KKVH-QVVK
n502_Tthe_PI4K   EKFHRLY--------KKSKSLVPDDSA--FRA---LK-----------K--FQKN-FKLQ
n508_Tthe_PI4K   -----------------------------------FK-----------K--TSMN-YQEP
n545_Tthe_PI4K   Q--NEEVSGISCV----------------------------------YEKGMRVP-----
n679_Tthe_PI4K   ------------------------------------YENR-------KDDLIQEQ-TALI
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  NTIVDKD--------A---------PVIF-----SEFNPLSLIGATAHMEAEEVN-KPFN
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  VETMLKI--------------QKFQKDYSKLAKNGDIIFDQTSFSFDESQPDYLLKLTVK
13773_Tthe_PI4K  LFHRIDQ--------------NEQAGDKDVLKKRKEILKNNQKKASR-------------
20618_Tthe_PI4K  MQEIIDI--------------KEFEEKVNSTANREGL--------------------IKG
20619_Tthe_PI4K  MQEILEM--------------KIYQEKIGQMMQREGM--------------------DRH
n8_Tthe_PI4K     --------------------------------------------------MFWSLRDDKT
n29_Tthe_PI4K    -QPSLKI--------------KKKSKKRYRA-AKIK-------------------IDKGE
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -QTSMDPDRLQKFEANIKVFNKNFPQKQNVN-RRNS-------------------LA---
n502_Tthe_PI4K   -ETFLEGERLQKYQENIKRFNIYFKEKKNVI-QR--------------------------
n508_Tthe_PI4K   -ET---RSRKEILKESKQKFNEKFPPKKLLR-ST--------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   IRE------------------------------------------------------DEN
n737_Tthe_PI4K   --------------------------------------------------MFYSLRDEKT
n858_Tthe_PI4K   --------------------------------------------------LYYSLRDDDH
GK310_Glam_PI3K  T-FISSR--------------PKSSKSRTRQS------------------IFKDKKDDRR
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  SNSQGFPNNNTSSLGGSRI-TYNQI--------------INQYS---VFNL---------
13773_Tthe_PI4K  -------------------------ARGRKEMQIGEDDYE--KD---LDEN---------
20618_Tthe_PI4K  IQDAEIEQKR---K--QLRDIWADRLYG----------NP--KD---IDTW---------
20619_Tthe_PI4K  KLQIEQELKR---Q--NLKDIWADRLRG----------NP--KE---LDTW---------
n8_Tthe_PI4K     MIQLGFQNAK---NRL--EDLWVYT--------------PQNQY---LAEL---------
n29_Tthe_PI4K    MDQNFFIKISQ---KSTWYKKIETT--------------IG---YANS------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   --------------------TICYN--------------PV-------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   PQQLK----------------------------------PSKNE---LQII---------
n737_Tthe_PI4K   MESMGLPNPYKSSHQSERHRNFNQT--------------PKTED---LARL---------
n858_Tthe_PI4K   MKQLGFPKLS---KRSNGGKNWNST--------------PKTDD---LARL---------
GK310_Glam_PI3K  AKQSPFSRRTQSKVRVSNRSSFSSQ--------------KDGDDRSSFSGIALSSSYTKH
GK311_Glam_PI3K  --------------------SFSVE--------------IPTQS---YGRS---------


29569_Tthe_PI4K  -----------------------I------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  NPASLHRDSAYDATYDVPEDDGISKNYGTRRSSAFSCTQAVFQRKLTTTIEYSTDNELSD
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -------------QA-LQQTSK---LLLSY------------------------------
13773_Tthe_PI4K  -------------EEDLEEERL---LYESRKKQSEKKRLEVNYWMDLIDIYS----HLNE
20618_Tthe_PI4K  -------------QK-ILSVRQL---YLSKK-----------------------------
20619_Tthe_PI4K  -------------QQ-ILSVRQI---YLSKK-----------------------------
n8_Tthe_PI4K     -------------KE-LLKRDPINR--NFD------------------------------
n29_Tthe_PI4K    ---------------------------------------------------SIFSLNLYY
n73_Tthe_PI4K    ---------------------------------------------------Q----EDQM
n131_Tthe_PI4K   --------------------------------------------------------HIEG
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ---------------------------------------------------S----HYNL
n679_Tthe_PI4K   -------------EN-S-IKKPIL--GELK------------------------------
n737_Tthe_PI4K   -------------QF-LLNADPLKRP-EFT------------------------------
n858_Tthe_PI4K   -------------QQ-LLSIDPLRRLSEQS------------------------------
GK310_Glam_PI3K  TSMLPPTLKAVARRV-SSNSDDNAY--NDN------------------------------
GK311_Glam_PI3K  -------------QV-MPK-----------------------------------------


29569_Tthe_PI4K  -DQECY------------------------------------------------LRIVY-
13773_Tthe_PI4K  KDQIKGILKKTVSHEGQKDMIVALDLKFSGQIQNSLKILKEISSKNKESERQN---QFRM
20618_Tthe_PI4K  -DDLNT--------------------------------------------WLK---FCRL
20619_Tthe_PI4K  -EDLQS------------------------------------------------------
n8_Tthe_PI4K     -MRQKL--------------------------------------------ILL---ICR-
n29_Tthe_PI4K    D-----------------------------------------------------------
n73_Tthe_PI4K    K-----------------------------------------------------------
n131_Tthe_PI4K   A-----------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   K-----------------------------------------------------------
n679_Tthe_PI4K   -QDEKL--------------------------------------------LFY---RFR-
n737_Tthe_PI4K   -PEDKH--------------------------------------------ILM---ISR-
n858_Tthe_PI4K   -EEDKH--------------------------------------------VLM---ICR-
GK310_Glam_PI3K  -PEDQH--------------------------------------------NEIDVSQKR-
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  AIEDNLNNQVSLDDRIQEYI-QSEYQDTLALMGKWDDLANELIEINKDVLEQPEKIGVEK
20618_Tthe_PI4K  ALK---NNQMHICKKTLEELY-LEYNKDSQLMPAQLQLAD--LECNYQMSITKEKEICEK
20619_Tthe_PI4K  --------------RMLDQIFQEEYQ-DEDEAPPNYHLAN--FECMYRINPSNFPEICEK
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    -----------------------------------------------------K--DKE-
n73_Tthe_PI4K    -----------------------------------------------------DSKLASN
n131_Tthe_PI4K   -----------------------------------------------------K--IKQ-
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -----------------------------------------------------D--LAQQ
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  MKILMLSLMQSDSADTSRWEELKDYVKLWMNTEYGKSVLEGPLSYEMALITILDGDIDRT
20618_Tthe_PI4K  MEEILQSENKI-------------------------------------------------
20619_Tthe_PI4K  MENYLKNEKKI-------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    TSSMVQESSQIQ-------------------------------NTID-------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   SASQIELNND-P-------------------------------NKNI-------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  RYYHKLSQNQFLRVWSNFGSFATASKHEYLSNIYKNYELKEYLHLDGKIEATYEDFNSLF
20618_Tthe_PI4K  ---------------------------------DNKLTAKMYLKMGNWIRDKTDELNS--
20619_Tthe_PI4K  ---------------------------------EKKQVAKMYLKMGIWMRETGEELDK--
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ---------------------------------KEKEIRPFYLRKAL-INLLSDEIDK--
n73_Tthe_PI4K    -----------------------------------------------GMEQP--------
n131_Tthe_PI4K   ---------------------------------RRKSIRDLKIK---------DAI----
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -----------------------------------------------SIPQN--------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  KNWQNRKPSNTYDNQICWDQILNSREIFALALYQKYNLEDQFVNKIRSNWYIQNVKGMLK
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  KGIHGAADRKMKKAAGYRKVMNGLPEFNW-------------------------------
20618_Tthe_PI4K  --------FNMKKIGEF---YQKAKDFKP-------------------------------
20619_Tthe_PI4K  --------QKIKKIEEY---FEKSKEFKS-------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    --------LRANSFSEF---IDKYNVIKNPYSLAGKQISKDDIVGIMKELMKKSPQLVLY
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -------------------NYLIC---------------------------VLYNQCKEY
13773_Tthe_PI4K  -------------------DYYKITS---KLKLK--------------------------
20618_Tthe_PI4K  -------------------DYYKTWH---HFGLL--------------------------
20619_Tthe_PI4K  -------------------DYYKTWH---HFALL--------------------------
n8_Tthe_PI4K     -------------------NHFKSIH---QALDI--------------------------
n29_Tthe_PI4K    ILRKLSFAIEKPQLAKFVRQNYKDHLNSSHFLEL--------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------DLFRFLKQNYQNK---YQFINK--------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -------------------YSLVQNP---EALVK--------------------------
n737_Tthe_PI4K   -------------------NHYKTLT---QALQV--------------------------
n858_Tthe_PI4K   -------------------NHYKTLT---HTLQI--------------------------
GK310_Glam_PI3K  -------------------NYYLKLL---CILKSYIETNNQDTHWGDYTFSV----CTKL
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------RKIY--INSL------FRLSKYYYKK-EKYSDALTI
13773_Tthe_PI4K  -----------------------QLEVDLKNDQIPENPF---EKFSKLI-KIFEQEKE-K
20618_Tthe_PI4K  ----------------------------------------NFDAINMKQDDTIIEQKR-V
20619_Tthe_PI4K  ----------------------------------------NFDVLDMMD-EIDTREKL-D
n8_Tthe_PI4K     ----------------------------------------FLCAVDWSNP-EHIRETYNL
n29_Tthe_PI4K    ----------------------------------------FIEYMN-SDK-ELMKE----
n73_Tthe_PI4K    ------------------------------------------------V-----------
n131_Tthe_PI4K   ----------------------------------------IYKYL---------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------N-----------
n679_Tthe_PI4K   ----------------------------------------FLHSINWDNQ-KELNEAKKL
n737_Tthe_PI4K   ----------------------------------------FLLAVDWLDP-EQVKEAILM
n858_Tthe_PI4K   ----------------------------------------FLFAIDWLDP-EQVKEAILM
GK310_Glam_PI3K  EALSPFLTYPLTYLTKLEYQHLWEYKDLALCDPVLL--FRLSQSINYKNK-DSVQSFYNI
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  --LK--------------------------------------------------------
13773_Tthe_PI4K  --YIHQLDQSQIVKFEQLNIQVNEKFIDVYQDYTLTQIVEDIFLEKYADVINNIYWGYNK
20618_Tthe_PI4K  --YIKNA-----------------------------------------------LEG---
20619_Tthe_PI4K  --YILNA-----------------------------------------------LEG---
n8_Tthe_PI4K     --LK--------------------------------------------------------
n29_Tthe_PI4K    ----------------------------------------------------NL------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   --LK--------------------------------------------------------
n737_Tthe_PI4K   --LK--------------------------------------------------------
n858_Tthe_PI4K   --LK--------------------------------------------------------
GK310_Glam_PI3K  LSAK--------------------------------------------------------
GK311_Glam_PI3K  STLQ--------------------------------------------------------


29569_Tthe_PI4K  -----------------RAKQ-VW------------------------------------
13773_Tthe_PI4K  LFQNDIMKKDIDLSSQSQSLSQPFENTFSFKGPASLPQMAGNNNFNSSEQIFEEIIPMRL
20618_Tthe_PI4K  ------FMRSITLGTSSEHKS-PY--------------------------I---------
20619_Tthe_PI4K  ------FMKSISIGTSSEHKS-PY--------------------------L---------
n8_Tthe_PI4K     -----------------QWKS-PP------------------------------------
n29_Tthe_PI4K    -----------------YWRQ-PH------------------------------------
n73_Tthe_PI4K    --------HTINEDSSAQD-----------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   --------KEININNSNEY-----------------------------------------
n679_Tthe_PI4K   -----------------IWAK-CS------------------------------------
n737_Tthe_PI4K   -----------------KWTP-LQ------------------------------------
n858_Tthe_PI4K   -----------------QWTL-LS------------------------------------
GK310_Glam_PI3K  -----------------KIED-VT------------------------------------
GK311_Glam_PI3K  -----------------KATI-LN------------------------------------


29569_Tthe_PI4K  ---------KEKK--------DSFS-SQEI--------------YTLQAKIEKKLGNIKK
13773_Tthe_PI4K  KSYKRFANFCEQLLRI----IESES-RDH--------------LKKTLK-----------
20618_Tthe_PI4K  ---------LQDSLRLLSIIFEYG---------------DLEDIHNKF------------
20619_Tthe_PI4K  ---------FQDCLRLLQIIFDYG---------------DFEEVAQLF------------
n8_Tthe_PI4K     ---------CEECITF----LDAHH-ADEV--------------IRLY------------
n29_Tthe_PI4K    ---------IQIMLKY----ISEGYESFPG--------------LQLF------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ---------YGDALHL----LSSSFCANEFYNKKYKKPQDTAIYIRKY------------
n737_Tthe_PI4K   ---------PEDALPL----LDAHI-SNEI--------------VRLY------------
n858_Tthe_PI4K   ---------PEDALPL----LDANM-ANES--------------VRLY------------
GK310_Glam_PI3K  ---------LDTVMNL----LASAQ-TDPI--------------IRGF------------
GK311_Glam_PI3K  ---------EEEVSSF----CEARF-GNMAD-------------LQFD------------


29569_Tthe_PI4K  AIHK---LQKFDGIDFKIKKVTYKYQHNFQI----------------------------F
13773_Tthe_PI4K  ----------------------VQYQLTVETVGSSFLEYTLKCFSLMGGINQFEQKSNKM
20618_Tthe_PI4K  -LEDFKQIDNR-------------------------------------------------
20619_Tthe_PI4K  -LEDFKNIDSR-------------------------------------------------
n8_Tthe_PI4K     GVER---ISKM-------------------------------------------------
n29_Tthe_PI4K    FTKTMKK---L-------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ---HY-------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ACEQ---LEKE-------------------------------------------------
n737_Tthe_PI4K   AVER---ISTF-------------------------------------------------
n858_Tthe_PI4K   AVER---VSTF-------------------------------------------------
GK310_Glam_PI3K  AVSV---LNTY-------------------------------------------------
GK311_Glam_PI3K  TMDM---SYTD-------------------------------------------------


29569_Tthe_PI4K  SESLIHSEFIKLVQQNSES---EKLCFKY-------------------------------
13773_Tthe_PI4K  QM---EVETGEKIQENPEKSQNQSIEFDQNMSNLVLKMLRIIQQIPNMTGQKFKEAIELQ
20618_Tthe_PI4K  AW----------------------------------------------------------
20619_Tthe_PI4K  AW----------------------------------------------------------
n8_Tthe_PI4K     AD----------------------------------------------------------
n29_Tthe_PI4K    QS----------------------------------------------------------
n73_Tthe_PI4K    -------------------------------------------------------MELHT
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -------------------------------------------------------SESNL
n679_Tthe_PI4K   QT----------------------------------------------------------
n737_Tthe_PI4K   SD----------------------------------------------------------
n858_Tthe_PI4K   SD----------------------------------------------------------
GK310_Glam_PI3K  SS----------------------------------------------------------
GK311_Glam_PI3K  SS----------------------------------------------------------


29569_Tthe_PI4K  --AKFIDENELISDNPNDKEIDQKIKAIQLYLLAASN-----------------------
13773_Tthe_PI4K  IIPSWIF------------------ISFLPQMMHILK-----------------------
20618_Tthe_PI4K  -------------------------IEVVPQIIARLS-----------------------
20619_Tthe_PI4K  -------------------------IEVVPQIIARIS-----------------------
n8_Tthe_PI4K     -------------------------DEIKLYMIELVQ-----------------------
n29_Tthe_PI4K    -------------------------EQLIFYLPQIYI-----------------------
n73_Tthe_PI4K    HIPHYIN-------------------------MNGQK-----------------------
n131_Tthe_PI4K   -----------------------------DVIEQT-------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   NQTNRNQ------------------SESIPQSVESIK-----------------------
n679_Tthe_PI4K   -------------------------STICSILLQLTQ-----------------------
n737_Tthe_PI4K   -------------------------DEIALYMLELTQ-----------------------
n858_Tthe_PI4K   -------------------------DEIALYMLELTQ-----------------------
GK310_Glam_PI3K  -------------------------YDLEPHIMQLVE-----------------------
GK311_Glam_PI3K  -------------------------DEAPTILLRSADDHTTSDDTKGTIGEHSQTSGREE


29569_Tthe_PI4K  -GHQY------I-HQ--SLPRA-IRLLVE-------------LFQDVANLQTKK------
13773_Tthe_PI4K  --------------KQNLVEFF-EPLIKKLAKNYPEALIYQFNT------IFSN------
20618_Tthe_PI4K  -TT-----------KKSVQHLL-HSLLTHIAQQHPQALIYPLTV------ALKS------
20619_Tthe_PI4K  -DS-----------KSGVQKIL-HELLIHISNHHSQALIYPLTI------ACKS------
n8_Tthe_PI4K     -ALMF------E-NN--HYSPI-QELLLERSLLNPFVVGHELFW------SLKS------
n29_Tthe_PI4K    -SLG---------S---KAGPIIRQFLIDYSQF-SVLFAHQLIW------MAKV------
n73_Tthe_PI4K    -PH-----------N---------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ----------------------RSSIVTDRNVNNPFRERHQ-YV------NAKE------
n508_Tthe_PI4K   ----------------------SQGILEAQ------------------------------
n545_Tthe_PI4K   -PS-----------KKY-------------------------------------------
n679_Tthe_PI4K   -ALRY------E-PFDYQKSHL-AQFLVKKACENTE-IATLFYW------YLLV------
n737_Tthe_PI4K   -LLLY------E-RN--HFSPL-AEMLLERSLLNPYVVGHEFFW------QLKS------
n858_Tthe_PI4K   -SILY------E-SK--HFSPL-VDMLLERSLQNPFVVGHELFW------QLKS------
GK310_Glam_PI3K  -LCKY------D-MV---NAGL-ASFLIRMAIKEFPTFGYPLYW------AFRC------
GK311_Glam_PI3K  SALVHNPAEPQRYLT---FKNL-SDMLIARAISAPYTF-YLFYF------YVDLWYSNSI


29569_Tthe_PI4K  ------AQL-VKQ-----------------KFD--------------------KN-----
13773_Tthe_PI4K  -------QTTCET--ALSQEIYEALH--------------------------KEM-----
20618_Tthe_PI4K  -------KIQIRQ--QAASKIIENIK--------------------------THS-----
20619_Tthe_PI4K  -------KTQIRQ--QAANQIISDIK--------------------------THS-----
n8_Tthe_PI4K     -------QLHLKQ-----------------SY--------------------ERY-----
n29_Tthe_PI4K    -------ESKNDEDKKKKKKIPENLKIIEQISKNLIDKIQRNMD-KNQQEFWFKV-----
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -------KL----------------------------NLKKRRKVSLK------D-----
n508_Tthe_PI4K   -------------------------------------KIQKFKN-AIK------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -------ECDKEMDLKEKAKLSSTNQKVQEWFN-------------------QVF-----
n737_Tthe_PI4K   -------QLNVKA-----------------FH--------------------ERF-----
n858_Tthe_PI4K   -------QLHIKA-----------------FY--------------------ERY-----
GK310_Glam_PI3K  -------EMRLNL-----------------VFS-------------------SAY-----
GK311_Glam_PI3K  RQQDENAQRKLLA-----------------CRD-------------------GYYAIMKE


29569_Tthe_PI4K  -----------FLQISETCNKI-ET-FKLTSVVNQLTSHITIPYQQCANLFIDLLAKTLN
13773_Tthe_PI4K  -----------PHYYNFMYHLN-QITHPEH-RLI--------------------------
20618_Tthe_PI4K  -----------PLLINQALLIS-QELNRTA-ILI--------------------------
20619_Tthe_PI4K  -----------PVLVNEAMLIS-NELNRAA-ILL--------------------------
n8_Tthe_PI4K     -----------ALVLEQLLMLS-GEY-RSE-LLK--------------------------
n29_Tthe_PI4K    -----------NSFFEQVTSIS-GML-RPQ------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   -------------V----------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -----------ERMNEELEEKC-EEN-HQV-LSL--------------------------
n737_Tthe_PI4K   -----------SLLIEQFIMVC-GSF-RKE-IAN--------------------------
n858_Tthe_PI4K   -----------FLIIEQMLMLC-GSF-RNE-LVV--------------------------
GK310_Glam_PI3K  -----------SLFMLKILLHLPENQRRSI-ILT--------------------------
GK311_Glam_PI3K  KDPEFYSCLRSTILFSQQLINISK--KSSE-LGS--------------------------


29569_Tthe_PI4K  YSFQYSLTNFYIQNQNNQLGAEYPD-----------------------------------
13773_Tthe_PI4K  ----------YYLEYLKSQ-----------------------------------------
20618_Tthe_PI4K  --------KEQWLEGIKE------------------------------------------
20619_Tthe_PI4K  --------KEQWHEGIYNSME---------------------------------------
n8_Tthe_PI4K     --------EVEVNNELKNIARKIKV-----------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   --------QSEFRQKLRQIVA---------------------------------------
n737_Tthe_PI4K   --------QVHVNGSLNSVAKIIQY-----------------------------------
n858_Tthe_PI4K   --------QVGVNDQIKKIGQEIQD-----------------------------------
GK310_Glam_PI3K  --------ELL-LIILLKLAKFSY------------------------------------
GK311_Glam_PI3K  --------VRH-ADQEKMIKKMIQDGTLLTALERKQNSDPSMDDEHSDPRLDSDKLGVIF


29569_Tthe_PI4K  --------------------------------------------------------QSVW
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     -----------------------------QKTN-EQ------------A-----------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   -----------------------------EAKQGVD------------K-----------
n858_Tthe_PI4K   -----------------------------ESLF-KE------------H-----------
GK310_Glam_PI3K  ----------------------------RKKKESID------------ASK---------
GK311_Glam_PI3K  PFVMLKNHQTTASDDAFVTAINLRRPMRHRRIESLNAASFSTEFNIFVTETENSNPSTVV


29569_Tthe_PI4K  WLLPLKYMYQMISNQSSVQKDEYTEQRASAILKKINEI---NPSS-----------YEQI
13773_Tthe_PI4K  --------------FLSFQKIHNTYSSQKDYVKLNKAVEEYQKII-----------DRIL
20618_Tthe_PI4K  ----------------AWERYTIDKGAHTHLIKILQGLHEMMKVP-----------PESL
20619_Tthe_PI4K  ----------------SFERFQSEKSTSSDLIKNVMELHETMTLQ-----------PESL
n8_Tthe_PI4K     ----------------------------KEVLE----------KE-----------LKRL
n29_Tthe_PI4K    -----------------------------------MPKPEKRAII-----------KEQL
n73_Tthe_PI4K    ------------------------------DNKEI-----------------------EI
n131_Tthe_PI4K   ----------------------------------------YTQNP-----------DQDL
n502_Tthe_PI4K   -----------------------------------------------------------L
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   -----------------NN-----------QVSDV-----------------------LD
n679_Tthe_PI4K   ----------------SMA----KKDR-----------TQKIEII-----------KKKL
n737_Tthe_PI4K   ----------------------------AKLQE----------RS-----------KEEL
n858_Tthe_PI4K   ----------------------------TLLVP----------LT-----------RKKL
GK310_Glam_PI3K  ----------------------G-----TQLRDV--------PSF-----------IGRI
GK311_Glam_PI3K  QSSPKKLCSDAVTD--------A-----SGTSSI--------PQFSVSPLQEEGDTKAVK


29569_Tthe_PI4K  NRV----------------------S-NFY-------------YN-LLNFAIKAPDGSST
13773_Tthe_PI4K  KETEEDLFQHNINADHMGSYN-----IKFSKDHISEFKKLVKKFTDITKGD---DQDKKE
20618_Tthe_PI4K  SEI---------------SFH----Q-NFGG-EIFEAESWLERYK-ITED----AICLCQ
20619_Tthe_PI4K  SEI---------------SFH----Q-NFGG-IINEAEAWIQRFS-ITEN----PICIYQ
n8_Tthe_PI4K     I-----------------------------------------------------------
n29_Tthe_PI4K    SLI---------------EVT----Q-DIYM-P---------------------------
n73_Tthe_PI4K    IPNGEKISTK--------TLS----KKLFGED----------------------------
n131_Tthe_PI4K   KEI---------------QFP----R-VFGP-W---------------------------
n502_Tthe_PI4K   KVI---------------DVL----R----------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   L---NDDKFK--------G-L----KNLFGED----------------------------
n679_Tthe_PI4K   ASE---------------EFKRPNFK-EHPF-CL--------------------------
n737_Tthe_PI4K   G-----------------------------------------------------------
n858_Tthe_PI4K   S-----------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  TM----KIENYLVKSLANLRLILPKKEYIFPKMPQSR-NVEP----NYN-------PYHN
13773_Tthe_PI4K  AYDFIKKFRDKVNTKDLKSGYD--KLSNFSSFLQNFQADHIIEIPGQYTSGAVITEPYKE
20618_Tthe_PI4K  AFDIYYRIYSKLDVQLKKLEFV--YLENVSPKLLETK-NCEVSIPGLYK-------P-TR
20619_Tthe_PI4K  AFDIYSQIYQKLKPQIKKLEFV--YLENVSPKLIETK-NCEISIPGMYK-------P-SR
n8_Tthe_PI4K     ------------NN---KYKQKGEGQEFTL---------------------------AID
n29_Tthe_PI4K    ----------------------------------------------------------TN
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   -----------------------------------------------------------N
n737_Tthe_PI4K   -----------------KIRDNLPKPTFSL---------------------------ALD
n858_Tthe_PI4K   -----------------EIK---LPEEFSF---------------------------ALD
GK310_Glam_PI3K  ------------NNLLTRLKNILKVDCFKL---------------------------PLS
GK311_Glam_PI3K  ------------NDVEKKPGNV-------L---------------------------VVD


29569_Tthe_PI4K  NPVYMEKF----------D-DVVRIMSS-KQKPKLLTV----------------------
13773_Tthe_PI4K  SHIKIQSF----------D-SQILTLQS-IRRPKRLCI----------------------
20618_Tthe_PI4K  PIVKISCF-----------QPKLEVLFS-KMNPRKLFV----------------------
20619_Tthe_PI4K  PVIKITCF-----------QPKLEVLPS-KTHPRKICI----------------------
n8_Tthe_PI4K     NRLQLNDF----------DTKKCKFMNS-KKKPLWLVM----------------------
n29_Tthe_PI4K    PRYQIASI----------NLDSGAPMQSAAKCPILVTFNC-R------KYEGPDKYFKTK
n73_Tthe_PI4K    QADQEKR-------------------IK-KKSPY---A----------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   SRDQEAR-------------------IR-KHSPF---G----------------------
n679_Tthe_PI4K   PNLMIVES----------IHQQSTVFKS-AMAPIKMTFTSY-------------------
n737_Tthe_PI4K   SRIQVTDF----------NLQGCRCMNS-KKKPLWIETINKVEIEEIDE-----------
n858_Tthe_PI4K   SRMQVQRF----------EIDDCKCMNS-KKVPLWIAT----------------------
GK310_Glam_PI3K  YDIKLATF----------CVVECAVLSS-KKAPLLLSL----------------------
GK311_Glam_PI3K  KNETYADFHKKFVHICGINPDNVKVMTS-AKRPILYHL----------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    VLEKKHIYKKAMIQKFREVGVNPLLFSERIVLTCENDDLDFEFKVDEDDQQAQATINNLN
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -----F---------FKH--------------------------LQRNYPQFEKEIQMI-
n508_Tthe_PI4K   ------------------------------------------------AAFFKAKIQDI-
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    SPLRIKPFPKSMNASLLSSHA-----NNNNGMHIADFITDIQDIKDQIEEPPVPP-ILKQ
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   -----------------YKH------------------LHYDELEEQIEHTKISNVDLLN
n508_Tthe_PI4K   -----------------IAH------------------------------ID-------N
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ----------NNNKSKLINQQINTQNI---------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ASSNLY---------------KEQNKKFQTQFKFTFHRDEDKLGVLRDKPGEQYLQLDVE
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ---------------------GELW--------------E--------------------
n502_Tthe_PI4K   EDEDISQKQISSFSIKRKFPWEDVW--------------E--------------------
n508_Tthe_PI4K   KDDIKSMQDIDSEPVRKLEPWGEFW--------------E--------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   --------------------FQQN-----------------------------------Q
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  ------------------------------------------------------------
GK311_Glam_PI3K  ------------------------------------------------------------


29569_Tthe_PI4K  -------------------------QCSDG-TKKKFLIKSQTQSENVYEQRTSELISFLN
13773_Tthe_PI4K  -------------------------YG-SD----EKCYKG--IEDLRLDQRIEQLFQVMN
20618_Tthe_PI4K  -------------------------YG-SDSKEYHFLLKG--REDIRQDERVMQLFALIN
20619_Tthe_PI4K  -------------------------YG-SDSKEYFFLLKG--HEDIRQDERVMQLFGLIN
n8_Tthe_PI4K     -------------------------KNAENQKEFSIMFKD--GDDLRQDILTLQLIRIMD
n29_Tthe_PI4K    KQDAIIEDEEAVNVVSIMKQSTDQINR-RPPEQVSCIFKV--FDDVRQDQLALQIITLFQ
n73_Tthe_PI4K    -------------------------HF-KSWKLVHFIVKT--GDNLKQEQFAQQLIYQFD
n131_Tthe_PI4K   DKQQV-----------IKEQ-SPFRIL-KSYKLRPFIIKG--GDDLRQELLIMQLIQKFH
n502_Tthe_PI4K   DKIIK-----------IKRE-SPYGQF-KSYKLRAVIFKG--GDDLRQELLAMQLIYKFQ
n508_Tthe_PI4K   DKKKL-----------IRAQ-SEYGKY-KSYQCRAVIFKG--GDDLRQEILAMQLIYKFQ
n545_Tthe_PI4K   -------------------------HF-KSWKLVHMIVKT--GDNIKQEQFAVQLIYQFD
n679_Tthe_PI4K   ----------------------PIGQK-EKEGKVEMIYKN--GDDLRQDQLVMQIFNLMD
n737_Tthe_PI4K   QQK-------------------E-IIS-ENDLEMKILFKR--GDDIRQDQLTLQLLKIMD
n858_Tthe_PI4K   -------------------------KS-KEDENINILFKC--GDDIRQDQLTLQLLKIMD
GK310_Glam_PI3K  -------------------------KTADGAFNYKCLFKT--HDDLRQDSLVLRTFSYIQ
GK311_Glam_PI3K  -------------------------IQAETGKEIPVLLKI--NDDVRLDMLYVHLFSLMD
                                                       *    .:   :    . :  :.

29569_Tthe_PI4K  LILYKE----QLGFYEMPSYTILRLN-----SQSCIVEWVDDTLTLKTILDQ-LWQ-EKK
13773_Tthe_PI4K  NIFEYDPQCQSKEL-NLSTFNIIPMT-----NILGLLEWVDKTSVLKEILNKEFQE-KMG
20618_Tthe_PI4K  RLLHNNPETEKKDL-NIQRYSIIPLS-----INTGLLGWVHNCDTLQVLIRE-YRK-AYH
20619_Tthe_PI4K  RLLQNNTETQKKGL-SITRYSIIPLS-----MKTGLLGWVQNCDTLQILIRD-YRK-AFN
n8_Tthe_PI4K     KIWLDN----NLDL-RMKPYNVVATL-----DQVGMLEIVQNSQTTAAIHKQ-NNQ-RFG
n29_Tthe_PI4K    GIFQKA----NLEL-YVFPYKTISNRTGNNLDIGGIIEVVKNSISRDQLGKT-NQ---C-
n73_Tthe_PI4K    QIFKD----SELNL-ILRPYEIISLG-----PNCGIIEVVKNSVTFDSLIQK-LNT-QQK
n131_Tthe_PI4K   EIFKQG----GVPL-YLRPYEIIVAS-----ESSGFIEFLPNTLSIDALKKK-YPK-FT-
n502_Tthe_PI4K   SIFQKA----NLQL-WLRPYEIIVTS-----ASSGIIEFLPNTYSIDGLKKK-VPK-FT-
n508_Tthe_PI4K   KIFMDA----GLKL-WLRPYEILVLS-----ASSGILEFLPDTLSIDALKKK-VDG-FT-
n545_Tthe_PI4K   QIFKM----EELDL-KLTPYEIVSLG-----PQSGILEMVKNSITLDGLLKQ-IHS-YKE
n679_Tthe_PI4K   GLLKGV----GQDF-RLMPYKVLACS-----KNDGFMEFVPNSTTIQDLLKG-GKQ-FSQ
n737_Tthe_PI4K   KIWLDA----GQDF-RMKPYKVITTG-----DQVGMIEVVVNAETTARIHKQ-EGG-GLG
n858_Tthe_PI4K   KIWLDA----GHDF-RMKPYKVITTD-----DQVGMIEIVNNSETTAKIHSK-YGG-VLG
GK310_Glam_PI3K  NVWYNN----NINL-AMKVYSCVATG-----PFEGLIELVPDSETLGSIEHT-FGG-ARG
GK311_Glam_PI3K  SYMQTH----NLDM-KFTIYSCFALS-----PSIGFIECILPSESQDDIYKK-KELGTIT
                              :  .  :  .            ::  :        :

29569_Tthe_PI4K  QKSQ----------------------------FY-QLKLDSDKLSREEWNKQK--SLPSV
13773_Tthe_PI4K  -SKEDIAQDNEGLRMRREWLKQLDRKGGLAEQHI-KLQLEPSDKIEQAFNEQADLIPRDV
20618_Tthe_PI4K  -IRE------------------------------------------------------NP
20619_Tthe_PI4K  -IKY-----------------------------GAELTL----------------MNDFN
n8_Tthe_PI4K     ---C---------------------------------------------------LMKES
n29_Tthe_PI4K    -----------------------------------------------------------S
n73_Tthe_PI4K    -G--------------------------------------------------------MN
n131_Tthe_PI4K   -----------------------------------------------------------N
n502_Tthe_PI4K   -----------------------------------------------------------C
n508_Tthe_PI4K   -----------------------------------------------------------N
n545_Tthe_PI4K   -I--------------------------------------------------------KD
n679_Tthe_PI4K   -Y-------------------------------LQNLAA----------------NPENP
n737_Tthe_PI4K   ---A---------------------------------------------------LKEDT
n858_Tthe_PI4K   ---A---------------------------------------------------FRNNT
GK310_Glam_PI3K  ---A---------------------------------------------------FARGP
GK311_Glam_PI3K  ---D---------------------------------------------------YFNAM


29569_Tthe_PI4K  FQ----------------------------------------------------------
13773_Tthe_PI4K  FR----------------------------------------------------------
20618_Tthe_PI4K  EYNLMEQKCSNY------------------------------------------------
20619_Tthe_PI4K  IYNFYDSSFNDY------------------------------------------------
n8_Tthe_PI4K     IQ----------------------------------------------------------
n29_Tthe_PI4K    LYDYFINKFG--------------------------------------------------
n73_Tthe_PI4K    LQ----------------------------------------------------------
n131_Tthe_PI4K   LYEFYRRTFN--------------------------------------------------
n502_Tthe_PI4K   LYDFYKDYFG--------------------------------------------------
n508_Tthe_PI4K   LYDFYQDTFG--------------------------------------------------
n545_Tthe_PI4K   LR----------------------------------------------------------
n679_Tthe_PI4K   IYEEYKRLRMQN------------------------------------------------
n737_Tthe_PI4K   LK----------------------------------------------------------
n858_Tthe_PI4K   IW----------------------------------------------------------
GK310_Glam_PI3K  IM---------KWLV------------DSINLHD---------EEFLRVQKNAQHNNSLT
GK311_Glam_PI3K  LC---------KYRSQVSPSVLSQALVKLPSLLSEISAKLLADE--------SLCLSSLI


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  -----SVLP---------------------------------------------------
20619_Tthe_PI4K  -----NKLP---------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  QEMRYSLLLEPEDDNRASETSELTISDVEQ------------------------------
GK311_Glam_PI3K  SESILDGKLPPQSPYAFSEFSDKTIPSVAGKGSLPFGEESYQMVKKRTRPSNLSSTSVHI


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  ------------------------------------------------------------
20619_Tthe_PI4K  ------------------------------------------------------------
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  SVLNKGYDDTNQGLFNTTAS----------------------------------------
GK311_Glam_PI3K  PNMSTSMDDLMGGIRSTKGAHKSVFSDDGVEKRQENSRGHSRHVSTSDCSYGGSEAKGSG


29569_Tthe_PI4K  ------------------------------------------------------------
13773_Tthe_PI4K  ------------------------------------------------------------
20618_Tthe_PI4K  -----------------------------------------------------------L
20619_Tthe_PI4K  -----------------------------------------------------------L
n8_Tthe_PI4K     ------------------------------------------------------------
n29_Tthe_PI4K    ------------------------------------------------------------
n73_Tthe_PI4K    ------------------------------------------------------------
n131_Tthe_PI4K   ------------------------------------------------------------
n502_Tthe_PI4K   ------------------------------------------------------------
n508_Tthe_PI4K   ------------------------------------------------------------
n545_Tthe_PI4K   ------------------------------------------------------------
n679_Tthe_PI4K   ------------------------------------------------------------
n737_Tthe_PI4K   ------------------------------------------------------------
n858_Tthe_PI4K   ------------------------------------------------------------
GK310_Glam_PI3K  --------------------------------------------------------VPTT
GK311_Glam_PI3K  DKGSETIESDKVMSAGATPSIQSRHTRGVPSNLSLQIGNRPLTQDIVQKWLVEQLTVKGI


29569_Tthe_PI4K  -------------------------DFFNQRFLDSQQWYTAKENYLRTYASWCILGYLIG
13773_Tthe_PI4K  -------------------------NALERLASTCETYLYLKERFIRNYAVVCVSGYILG
20618_Tthe_PI4K  PNKVEIFRYIME---NTKGEELK--KILWLKSPNSEIWLERRTNYTRSLATMSIAGYILG
20619_Tthe_PI4K  LNKVEIFRYIMQ---NTLGEDLK--KLLWLKSPNSEIWLERRTNYTRSLATMSIAGYILG
n8_Tthe_PI4K     -------------------------KYLKKH---NKNYEQARANFRTSCAGYCVATYILG
n29_Tthe_PI4K    -------------------------------QEDSANFQVARENFIKSQAAYSVISYILQ
n73_Tthe_PI4K    -------------------------EFFK--SYYGSGLYKAQKNFCSSLAAYSLVCYFLQ
n131_Tthe_PI4K   -----------------------------------DYFEEAQKNFIESLAGYSLICYLLQ
n502_Tthe_PI4K   -----------------------------------KQFQQAQSNFIESLAGYSIVCYLLQ
n508_Tthe_PI4K   -----------------------------------DYFDEAQKNFIESLAGYSIVSYLLQ
n545_Tthe_PI4K   -------------------------HFFQ--LYYGSQFKKAQYNFCSSLAAYSLVCYFLQ
n679_Tthe_PI4K   ----------------DEQGKLS--N------I-EYVSQKIMENYMLSCAGYSVMTYFLG
n737_Tthe_PI4K   -------------------------NYLQKHNPDKENLKSATENFIRSCAGYCVATYILG
n858_Tthe_PI4K   -------------------------QYLKDKNMDPHSFEIATDNFLRSCAGYCVATYILG
GK310_Glam_PI3K  LNTRSLYSKSSR---DSIFQSVSQLSLIQK--HTATRYTQMISNYLTSIAAYCVATCILG
GK311_Glam_PI3K  ESLPQKVYAIIGSVIDKVYRFNGPLN---C--MNDITAEAQMSNFVKSTAAYSVATYLLR
                                                            .:  . *  .:   ::

29569_Tthe_PI4K  LGDRHTDNILIKKINGEIVHIDYALIFGSGKQ-L----------N-VPETIPFRLTKNME
13773_Tthe_PI4K  IGDRHLENFLVNYSNGDIVSIDFGYSFGAGLGL------------AVPELMPFRLTRCFT
20618_Tthe_PI4K  LGDRHPSNIMLQRYTGKIVHIDFGDCFEVAMRRE----------K-FPEKVPFRLTRMLV
20619_Tthe_PI4K  LGDRHLSNIMLQRQTGKIVHIDFGDCFEVAMRRE----------S-LPEKVPFRLTRMLV
n8_Tthe_PI4K     IGDRHSDNIMITK-EGHFFHIDFGHFLGNFKKKF----------GINRERSPFVFTRVME
n29_Tthe_PI4K    IKDRHNGNILIND-KGHIIHIDFGFIFDISPANN-----------LRFESANFKLTKEMI
n73_Tthe_PI4K    IKDRHNGNILLH-KDGYICHIDFGFLLSNAPGNNLIQKNNQRQGVGFELNVPFKLLTDYI
n131_Tthe_PI4K   IKDRHNGNILIDN-QGHIIHIDFGFTLSIAPG-G-----------IKFETAHFKLTNEYV
n502_Tthe_PI4K   FKDRHNGNILIDN-SGHLIHIDYGFMFCISPG-G-----------INFENAPFKLTKEYA
n508_Tthe_PI4K   FKDRHNGNILINN-EGRLIHIDFGFMFSISPG-N-----------MNWENAPFKLTKEYV
n545_Tthe_PI4K   IKDRHNGNILLH-KNGHIIHIDFGFFLSNAPGKG----------LSIEQNVPFKLLSDYI
n679_Tthe_PI4K   VGDRHLENLMVD-ITGKFFHIDFGFILGQDPK---------------PYPPPLKLCRQMI
n737_Tthe_PI4K   IGDRHPDNIMLSQ-TGHLFHIDFGHFLGNFKKKL----------GIDRERAPFVFTEEMA
n858_Tthe_PI4K   IGDRHADNIMLSQ-TGHLFHIDFGHFLGNFKTKF----------GIKRERAPFVLTKEMA
GK310_Glam_PI3K  LGDRHNDNIMLCQ-DGTFFHIDFGHFLGNFKKKF----------NYERERGPFFFIPDMA
GK311_Glam_PI3K  AGDRHGENLLIRP-DGRMFHIDFGWCFGKDPKLM---------------APKMKVSKDLV
                   ***  *:::    * :  **:.  :                         : .

29569_Tthe_PI4K  FALGSF-K----S--YGLFRKAMIDICMCFSKHLDDIIGFWDCFTNEL------------
13773_Tthe_PI4K  NLMSPI-G----IN--GIFRQSMISSMMALKKKRNILLEFCEVFINDPLVDWVKLTKDKK
20618_Tthe_PI4K  NAMEAC-Q----I--EGNYRNTCELVLKVIRENKESLIAVLEAFVYDPLFYWRLITISG-
20619_Tthe_PI4K  NAMEAC-G----I--EGNYRNTCELVVKVIRENKESLIAVLEAFVYDPLFYWIVFTMSG-
n8_Tthe_PI4K     YVMLEK-Q-----EDYEAFEKYCCQAYNLIRKHGNFFINIFRMMLSAGM-----------
n29_Tthe_PI4K    QIMGGSKD----SEAFQYYVNLTIKGFLTMRNYFEHIYNTIRLMVA-S------------
n73_Tthe_PI4K    NVLGGV-N----SDLFKQFRQLFHKGFMAARKNQDKILILVKMFYSSHGA----------
n131_Tthe_PI4K   ALMGGR-N----SDQFGYYKSLLVRAFIEIKKHVNTICNLVQIMCDQS------------
n502_Tthe_PI4K   QLMGGK-E----SEGFERYKNLVFQGFKELQKYVDEIIFLVQIMQEES------------
n508_Tthe_PI4K   QLMGGQ-Q----SDQYSYYKDLLFMGFQAILEKVEDIIFMVQIMQEDS------------
n545_Tthe_PI4K   SILGGI-E----SDMFQTFRRLFFQGFQAACKHQDKILILVKMLYSGHGL----------
n679_Tthe_PI4K   EGMGGK-D----SKVYAEFRKKCVHAYIYLRKYAKLIVNLFHLMIDSGI-----------
n737_Tthe_PI4K   FVMGGK-E----SADFKNFTDYCTQAYNLIRKQGNFIINIFLLMLDAGI-----------
n858_Tthe_PI4K   FVMGGK-D----GNLFRKFEEYCTQAYNLVRKSGNFIINIFLLMLEAGM-----------
GK310_Glam_PI3K  FVLKHH-DYVNGTEYEKCFEKMSADALLAIRHHSSALISLFTIMIPSGI-----------
GK311_Glam_PI3K  KAMGGE-G----SADFESYLNYVAEIFCMLRQDVYIIISLLYILQGGGM-----------
                   :               :            .    :      :

29569_Tthe_PI4K  ----------EGCK----------------------------------------------
13773_Tthe_PI4K  MGTIMFSENIGHLDS---------------------------------------------
20618_Tthe_PI4K  --------EEQGDKANEKKEKGDAVYQANKKRESRPQSLLEVSMVNQVSYV-GSIIQQGT
20619_Tthe_PI4K  --------DLDSMKSPQEAK-------------------------NGISRRNSQIISNN-
n8_Tthe_PI4K     ----------PELQR---------------------------------------------
n29_Tthe_PI4K    --------SLPCFLK---------------------------------------------
n73_Tthe_PI4K    --------SLPCFEK---------------------------------------------
n131_Tthe_PI4K   --------NLPCFDE---------------------------------------------
n502_Tthe_PI4K   --------DLPCFRG---------------------------------------------
n508_Tthe_PI4K   --------DLPCFKY---------------------------------------------
n545_Tthe_PI4K   --------TLPCFEK---------------------------------------------
n679_Tthe_PI4K   ----------KDMS----------------------------------------------
n737_Tthe_PI4K   ----------PELQS---------------------------------------------
n858_Tthe_PI4K   ----------PELQS---------------------------------------------
GK310_Glam_PI3K  ----------PQLTS---------------------------------------------
GK311_Glam_PI3K  ----------AYLDE---------------------------------------------


29569_Tthe_PI4K  -------------------------------------------------------K-TNF
13773_Tthe_PI4K  -------------------------------------------------------TKT--
20618_Tthe_PI4K  SQAIQKYIKKAQKSKINNQNDIDRAQSPKNREKDIQEKYYNEEKEQPQENLNKKAV-EV-
20619_Tthe_PI4K  SGNINSFDYKEFE--TEQNEDINKLRLQKEEMKKAGDKD---KLQQPQDLFNKKAV-EI-
n8_Tthe_PI4K     -------------------------------------------------------E-SD-
n29_Tthe_PI4K    ---------------------------------------------------------NS-
n73_Tthe_PI4K    -------------------------------------------------------G-E--
n131_Tthe_PI4K   ---------------------------------------------------------FD-
n502_Tthe_PI4K   ---------------------------------------------------------FD-
n508_Tthe_PI4K   ---------------------------------------------------------FD-
n545_Tthe_PI4K   -------------------------------------------------------G-E--
n679_Tthe_PI4K   -------------------------------------------------------I-EA-
n737_Tthe_PI4K   -------------------------------------------------------A-KN-
n858_Tthe_PI4K   -------------------------------------------------------P-QD-
GK310_Glam_PI3K  -------------------------------------------------------R-ED-
GK311_Glam_PI3K  -------------------------------------------------------A-AQ-


29569_Tthe_PI4K  NQLCNQIKNRIK---------------------MTNFK-ST---EEG---I---------
13773_Tthe_PI4K  -YNAEQSQSQQQ---------------------Y-GL-STM-EASQI---ADLMIHMQRI
20618_Tthe_PI4K  ---MDRIKKKLN---------------------GKDFQ-EN-ESLTYTEQV---------
20619_Tthe_PI4K  ---MDRIKKKLN---------------------GRDFK-EN-EQLSYVDQV---------
n8_Tthe_PI4K     ---IEYLVETLQ---------------------L-NLS-DQ-EAEQH---F---------
n29_Tthe_PI4K    ---MKNLVSRFV---------------------L-DKN-DI-EAAKY---M---------
n73_Tthe_PI4K    -EAIKALEERFN---------------------PKNIKLEN-EYFVH---T---------
n131_Tthe_PI4K   ---MIQFRGRFK---------------------E-NFT-DK-EFIDY---V---------
n502_Tthe_PI4K   ---IKVFRERFQ---------------------E-HLD-EK-NLLLY---V---------
n508_Tthe_PI4K   ---QQVFRQRFREDLKNNDVGVKYQMILSDTFQI-NFQ-QKQQLRQY---V---------
n545_Tthe_PI4K   -QCILDLEQRFN---------------------PPNISNDG-ELSMH---C---------
n679_Tthe_PI4K   ---LEKLAEKFY---------------------L-DFN-DT-QAELH---F---------
n737_Tthe_PI4K   ---IEYLKNKLA---------------------L-QLS-EQ-EATNK---F---------
n858_Tthe_PI4K   ---IEYLRNQLS---------------------I-NLT-EQ-EATNK---F---------
GK310_Glam_PI3K  ---VQWIEDHLF---------------------L-DMS-ES-EAHRH---F---------
GK311_Glam_PI3K  -SHFYVIEDNYQ---------------------L-SLE-RD-AAIYY---I---------


29569_Tthe_PI4K  ------------DSLIQISKDDYC--LRDMFKG---------------------------
13773_Tthe_PI4K  DIVKLKLIGMNPSHLFTEELSSTRHKTGNYFQHLKSALKGKPKSIRNQYNEKQFLEVHEQ
20618_Tthe_PI4K  ------------SKLINQATSHE--NICQAYIG---------------------------
20619_Tthe_PI4K  ------------NKLILQATSDE--NICQAYIG---------------------------
n8_Tthe_PI4K     ------------KKQIRIAREDKFKLFDNFIH----------------------------
n29_Tthe_PI4K    ------------RNIIYDAYDKFTTRWYDDIQY---------------------------
n73_Tthe_PI4K    ------------NQLIDQSLDNWKSRWYDKWQY---------------------------
n131_Tthe_PI4K   ------------DELIKGSCDKWSTNQYDKFQL---------------------------
n502_Tthe_PI4K   ------------NKLINDSYDNWRTKQYDNFQK---------------------------
n508_Tthe_PI4K   ------------EKLVSDSYDNTRTNLYDYFQL---------------------------
n545_Tthe_PI4K   ------------NMLINQSLDNWRARWYDKWQY---------------------------
n679_Tthe_PI4K   ------------LNILDESETALFARVTDMIHKWA-------------------------
n737_Tthe_PI4K   ------------KKEIHFSLNSRFRKLDNLIH----------------------------
n858_Tthe_PI4K   ------------KKEITDSLNSLFRRIDNFFHG---------------------------
GK310_Glam_PI3K  ------------IRLIHEAERSKRYLYNNMFHILAHYK----------------------
GK311_Glam_PI3K  ------------LDVVKASMKAIMGQFIDAFHRFT-------------------------
                                .            :

29569_Tthe_PI4K  --------------------WWPHA
13773_Tthe_PI4K  VDCLIDLAVDPNIIGRVWIGWAPII
20618_Tthe_PI4K  --------------------WCPFW
20619_Tthe_PI4K  --------------------WGPFW
n8_Tthe_PI4K     --------------------EIVKK
n29_Tthe_PI4K    ------------------LQNKIYR
n73_Tthe_PI4K    ------------------FCQGIFY
n131_Tthe_PI4K   ------------------MQNGILP
n502_Tthe_PI4K   ------------------MTNGIAP
n508_Tthe_PI4K   ------------------KSNGIKP
n545_Tthe_PI4K   ------------------FCQGIFY
n679_Tthe_PI4K   --------------------TYWRA
n737_Tthe_PI4K   --------------------NLVKQ
n858_Tthe_PI4K   --------------------LRRRK
GK310_Glam_PI3K  ----------------KRRGSASSN
GK311_Glam_PI3K  --------------------QGFKK