Protein (view, download) , Domain (view, download)
PLK4_Hsap_SAK                 -FKVGNLLGKGSFAGVYRAESIHT--GLEVAIKMIDKKAM--------------------
PLK3_Hsap_PLK2                -YLKGRLLGKGGFARCYEATDTET--GSAYAVKVIPQSRV--------------------
PLK2_Hsap_PLK2                -YCRGKVLGKGGFAKCYEMTDLTN--NKVYAAKIIPHSRV--------------------
PLK1_Hsap_PLK1                ------FLGKGGFAKCFEISDADT--KEVFAGKIVPKSLL--------------------
polo_Dmel_PLK1                -YKRMRFFGKGGFAKCYEIIDVET--DDVFAGKIVSKKLM--------------------
SAK_Dmel_SAK                  -YEVQHLLGKGGFATVYKARCLHT--HQDVAIKMIDKKLI--------------------
PLK5_Mmus_PLK2                -YRRGKLIGKGAFSRCYKLTDMST--SAVFALKVVPRGGA--------------------
PLK4_Mmus_SAK                 -FKVGNLLGKGSFAGVYRAESIHT--GLEVAIKMIDKKAM--------------------
PLK3_Mmus_PLK2                -YTKGRLLGKGGFARCYEATDTES--GIAYAVKVIPQSRV--------------------
PLK2_Mmus_PLK2                -YCRGKVLGKGGFAKCYEMTDLTN--NKVYAAKIIPHSRV--------------------
PLK1_Mmus_PLK1                ------FLGKGGFAKCFEISDADT--KEVFAGKIVPKSLL--------------------
plk-2_Cele_PLK1               -YEKGKFLGKGGFAHCYELRNKST--GELFAGKVVPKALL--------------------
plk-1_Cele_PLK1               -YEKGRFLGKGGFAHCYELTNRAT--REVVAGKVVPKSML--------------------
F55G1.8_Cele_PLK1             -YEKGAFLGEGGFAHCFEFRKLDC--NDRLAVKVVPKVIL--------------------
CDC5_Scer_PLK1                -YHRGHFLGEGGFARCFQIKDD-S--GEIFAAKTVAKASI--------------------
zyg-1_Cele_SAK                -YSHLKEIGKGGFGVVYAAQR-EN--GEKVAIKRVSFMLFSKDIRMGQFFYFFSLQKLYF
PLK_Ddis_PLK1                 -YRQGEFLGKGGFAKCYLMTEVET--NRIYAAKIIPKSTL--------------------
8635_Tthe_SAK                 ------------------------------AMKVVDKKRK--------------------
8635~b_Tthe_SAK               -----------------------DQS--EINEQIKRQSQI--------------------
18358b_Tthe_PLK-Unclassified  ---------KGGFAKCYEFTNLER--KQVLAAKVIPKSSL--------------------
18380_Tthe_PLK-Unclassified   -YSRGKLLGSGGFAKCYEVIALDTDPKAIFAAKIIPKSTL--------------------
21183_Tthe_SAK                ------------------------------------------------------------
22503_Tthe_PLK-Unclassified   -YEVLSKLGKGGFAKVYLAKDISS--NEQYAIKVVDKSSL--------------------
5034_Tthe_SAK                 -YIISHPIGSGAGSLVVKVKSIKT--KKEYAIKVVDKQSQ--------------------
8829_Tthe_PLK-Unclassified    -YLRGKLLGKGGFAKCYEVTNLET--KKIIAAKIIPKQTL--------------------
SAK_Spur_SAK                  -YQVLNLLGRGGFACVYRAKTIST--GQEVAIKMIDKKLM--------------------
PLK1_Spur_PLK1                -YTKGRFLGKGGFAKCYELTDDAT--KQIFAGKVVSKALL--------------------
PLK2_Spur_PLK2                ----------GGFARCYELTHLDT--HYVYAGKIVPKERI--------------------
n1170_Tthe_PLK-Unclassified   -YQRGSLLGKGGFAKCFQVTNLEN--KKVMAAKIIPKSTL--------------------
n808_Tthe_PLK-Unclassified    -YQRGSLLGKGGFAKCFQVTNLEN--KKVMAAKIIPKSTL--------------------
CC1G_07437_Ccin_PLK1          -FNRVGFLGEGGFARVYEVQDP-R--GSRLACKVVTKSAL--------------------
AqueK200_Aque_PLK1            -YEKGRFLGKGGFAKCYELICEET--GTVYAGKIVAKELL--------------------
AqueK201_Aque_SAK             DYEVLNRLGKGSFADVYRAKCKRT--KKEVAIKMIDKKLM--------------------
GK066_Glam_PLK-Unclassified   -YRPGKLLGKGGFAYVYEFHDVNS--DSSYACKITPRSAL--------------------


PLK4_Hsap_SAK                 --YKAGMVQRVQNEVKIHCQLKH-PSILELYNYFEDSNYVYLVLEMCHNG----EMNRYL
PLK3_Hsap_PLK2                --AKPHQREKILNEIELHRDLQH-RHIVRFSHHFEDADNIYIFLELCSRK----SLAHIW
PLK2_Hsap_PLK2                --AKPHQREKIDKEIELHRILHH-KHVVQFYHYFEDKENIYILLEYCSRR----SMAHIL
PLK1_Hsap_PLK1                --LKPHQREKMSMEISIHRSLAH-QHVVGFHGFFEDNDFVFVVLELCRRR----SLLELH
polo_Dmel_PLK1                --IKHNQKEKTAQEITIHRSLNH-PNIVKFHNYFEDSQNIYIVLELCKKR----SMMELH
SAK_Dmel_SAK                  --QGTGLTNRVRQEVEIHSRLKH-PSVLQLYTFFQDANYVYLVLELAHNG----ELHRYM
PLK5_Mmus_PLK2                --GRLRLRGKVEREIALHSRLRH-RNIVAFHAHFADRDHVYMVLEYCSRQVPLQSLAHVL
PLK4_Mmus_SAK                 --YKAGMVQRVQNEVKIHCQLKH-PSVLELYNYFEDNNYVYLVLEMCHNG----EMNRYL
PLK3_Mmus_PLK2                --AKPHQREKILNEIELHRDLQH-RHIVRFSHHFEDADNIYIFLELCSRK----SLAHIW
PLK2_Mmus_PLK2                --AKPHQREKIDKEIELHRLLHH-KHVVQFYHYFEDKENIYILLEYCSRR----SMAHIL
PLK1_Mmus_PLK1                --LKPHQKEKMSMEISIHRSLAH-QHVVGFHDFFEDSDFVFVVLELCRRR----SLLELH
plk-2_Cele_PLK1               --IKQYQRDKMAQEVQIHRNLQH-RNVVKLYHFFEDKSNVYITLELCPRR----SLMELH
plk-1_Cele_PLK1               --VKQYQRDKMTQEVQIHRELGH-INIVKLFNFFEDNLNVYITLELCARR----SLMELH
F55G1.8_Cele_PLK1             --LKSTAREKLTREVEIHRQLSH-RNIVQFHHFFEDSQNVYFTLELCSKN----SLMELN
CDC5_Scer_PLK1                --KSEKTRKKLLSEIQIHKSMSH-PNIVQFIDCFEDDSNVYILLEICPNG----SLMELL
zyg-1_Cele_SAK                QIDKKVPKNRVWTEIQTMKELKKSKYVVEFYEDFVEDGYTYIVMELCEGG----SLQAYV
PLK_Ddis_PLK1                 --QKTRARSKLKSEIKIHSSLSH-ENIVKFEHCFENEENVYILLELCNQK----TVMDIH
8635_Tthe_SAK                 --DIQNVMKRLDQEIKIQKELDH-PNIIKLFKHFEDDQNHYLIMELAQNG----EIKDYL
8635~b_Tthe_SAK               --VQKKDDLKILNEIEIIGDIQNI-EQINKGGFGS-----------IQKG----KLAKIL
18358b_Tthe_PLK-Unclassified  --TKSRARQKLMSEIRIHKSLNH-RNIVKFQHFFEDQENVYILLEMCTNQ----TMNELI
18380_Tthe_PLK-Unclassified   --TKSRQRVKLISEIKIHKSLHH-KNIVQFEHVFEDHDNVYILLELCPYQ----TLNELI
21183_Tthe_SAK                ----------------LHSQLDH-PNIVKILKRFEDNEYVYMMLEYCPGG----SLFDYI
22503_Tthe_PLK-Unclassified   --EKDSFKEKLNQEIKIQKSLNH-ENVVKYYTSFEDSQNVYIVLEYCSNQ----EL---L
5034_Tthe_SAK                 --YYKSAYKRLKNEIEIHLDLKH-KNIVKMIKSFEDSENLYLVMEYCEGG----DLFHYL
8829_Tthe_PLK-Unclassified    --TKNRARQKLISEIKIHKSLNH-QHVVAFEHVFEDHENVYILLELCTNH----TLNELI
SAK_Spur_SAK                  --QSSGMATRVKNEVEIHCQLKH-PSILELYSYFEDNNYVYLVLELAQNG----ELLRYL
PLK1_Spur_PLK1                --VKPHQKDKMTMEIHIHKSLHH-RHVVGFHSFFEDKENVYVLLELCRRR----SLMELH
PLK2_Spur_PLK2                --SKPSQREKMEREIAVHAQLRH-PHIVGFHKHFQDAENIYILLELCRHK----SLLHML
n1170_Tthe_PLK-Unclassified   --VKNRARQKLISEIKIHKSLHH-NNIVKFEHVFEDHDNVYILLELCPHQ----TLNELI
n808_Tthe_PLK-Unclassified    --VKNRARQKLISEIKIHKSLHH-NNIVKFEHVFEDHDNVYILLELCPHQ----TLNELI
CC1G_07437_Ccin_PLK1          --KTKKAKTKLYAEIKIHRSLDH-PNIVTFIDCFEDEDNVYITLELCPSG----SLMDML
AqueK200_Aque_PLK1            --VKPHQKEKMTQEIEIHRSLSH-KHVVGFHGFFDDSNNVYILLELCKRR----SLMELH
AqueK201_Aque_SAK             --VKKGMTERVKNEVKIHSHLKH-PSILELYDFFEDSNYVYLILEFCQNG----ELNRYL
GK066_Glam_PLK-Unclassified   --QKKKYYDKFVTEVTIHRGLVH-PNICRVLNVFKDQMNYYIILEKCNGG----TLTDLI
                                                  : :                                :

PLK4_Hsap_SAK                 -------KN-----RVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTR---
PLK3_Hsap_PLK2                -------KA-----R-HTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITE---
PLK2_Hsap_PLK2                -------KA-----R-KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINE---
PLK1_Hsap_PLK1                -------KR-----R-KALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNE---
polo_Dmel_PLK1                -------KR-----R-KSITEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLND---
SAK_Dmel_SAK                  -------NH-----IARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSR---
PLK5_Mmus_PLK2                -------KV-----R-RTLTEPEVRYYLRGLVSGLRYLHQQRIVHRDLKPSNFFLNK---
PLK4_Mmus_SAK                 -------KN-----RMKPFSEREARHFMHQIITGMLYLHSHGILHRDLTLSNILLTR---
PLK3_Mmus_PLK2                -------KA-----R-HTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITD---
PLK2_Mmus_PLK2                -------KA-----R-KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINE---
PLK1_Mmus_PLK1                -------KR-----R-KALTEPEARYYLRQIVLGCQYLHRNQVIHRDLKLGNLFLNE---
plk-2_Cele_PLK1               -------KR-----R-KAVTEPEARYFTYQIVEGVLYLHNLKIVHRDLKLGNLFLND---
plk-1_Cele_PLK1               -------KR-----R-KAVTEPEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLND---
F55G1.8_Cele_PLK1             -------KQ-----R-GPLTEHEARFYTIQVAEGVKHLHNLQIIHRDLKLGNLFLNE---
CDC5_Scer_PLK1                -------KR-----R-KVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDS---
zyg-1_Cele_SAK                -------RE-----H-GALDDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKK
PLK_Ddis_PLK1                 -------KK-----R-KYLMEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFI-D---
8635_Tthe_SAK                 -------NI-----N-K----------PYQLACGIKYLHDKDIVHRDLKLNNVLLSN---
8635~b_Tthe_SAK               -------KYPLYGHFSQTMSLITKLYIMWQIAQGIQFLTSKNVAHLDLKPANIVISK---
18358b_Tthe_PLK-Unclassified  -------RR-----R-KRLTELEVQCYLLQILYSIKYLHDNRVIHRDLKLGNLFLSD---
18380_Tthe_PLK-Unclassified   -------KR-----R-KRITEYETQIYVMQIVNALKYLHQNKIIHRDLKLGNLFLGD---
21183_Tthe_SAK                VYINFQLFE-----K-TRLNEDEARDISYQIVQGLEYLHKNKIIHRDLKPGNILLTG---
22503_Tthe_PLK-Unclassified   -------DR-----R-KRLTEIEVKSHLFQIIQSLKYIHSKGVIHRDLKIANIFLND---
5034_Tthe_SAK                 -------KH-----H-KKLSETEAKRITYKLAEGLKYLHDKSIIHRDLKLGNVLLSS---
8829_Tthe_PLK-Unclassified    -------KR-----R-KRLTELEVQCYVVQIVNALKYLHSHKVIHRDLKLGNLFLNE---
SAK_Spur_SAK                  -------KK-----KARVFGEEEARQFLEEIVIGLLYLHSHGILHRDLTLANILLTR---
PLK1_Spur_PLK1                -------KR-----R-KAITEPETRYFMRQCILACQYLSKTKVIHRDLKLGNLFIDD---
PLK2_Spur_PLK2                -------KL-----R-KHLTEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTD---
n1170_Tthe_PLK-Unclassified   -------KR-----R-KRITELETLCYTVQIVQALKYLHQNRVIHRDLKLGNLFVGE---
n808_Tthe_PLK-Unclassified    -------KR-----R-KRITELETLCYTVQIVQALKYLHQNRVIHRDLKLGNLFVGE---
CC1G_07437_Ccin_PLK1          -------RR-----R-RRFTEPETRFFMVQLIGACHYMHTHQVIHRDLKLGNLFLDA---
AqueK200_Aque_PLK1            -------KR-----R-KALTEPEVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLND---
AqueK201_Aque_SAK             -------KH-----RQKSLSE-DERIILNQVVKGLIYLHSFNIVHRDLSLSNILLTS---
GK066_Glam_PLK-Unclassified   -------RR-----R-KHLTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLME---
                                                               .  .:    : * *:.  *...

PLK4_Hsap_SAK                 -NMNIKIADFGLATQLKMPH-------------EKHYTLCGTPNYISPEI----------
PLK3_Hsap_PLK2                -NMELKVGDFGLAARLEPPE-------------QRKKTICGTPNYVAPEV----------
PLK2_Hsap_PLK2                -AMELKVGDFGLAARLEPLE-------------HRRRTICGTPNYLSPEV----------
PLK1_Hsap_PLK1                -DLEVKIGDFGLATKVEYDG-------------ERKKTLCGTPNYIAPEV----------
polo_Dmel_PLK1                -LLHVKIGDFGLATRIEYEG-------------ERKKTLCGTPNYIAPEI----------
SAK_Dmel_SAK                  -EMHVKIADFGLATQLKRPD-------------ERHMTMCGTPNYISPEV----------
PLK5_Mmus_PLK2                -NMEVKIGDLGLAARVGPAG-------------RCHRVLCGTPNFQAPEV----------
PLK4_Mmus_SAK                 -NMNIKIADFGLATQLNMPH-------------EKHYTLCGTPNYISPEI----------
PLK3_Mmus_PLK2                -NMELKVGDFGLAARLEPPE-------------QRKKTICGTPNYVAPEV----------
PLK2_Mmus_PLK2                -AMELKVGDFGLAARLEPLE-------------HRRRTICGTPNYLSPEV----------
PLK1_Mmus_PLK1                -DLEVKIGDFGLATKVEYEG-------------ERKKTLCGTPNYIAPEV----------
plk-2_Cele_PLK1               -ELQVKIGDFGLATTCDN-D-------------ERKKTLCGTPNYIAPEV----------
plk-1_Cele_PLK1               -DLVVKIGDFGLATTVNG-D-------------ERKKTLCGTPNYIAPEV----------
F55G1.8_Cele_PLK1             -HLQVKIGDFGLATFCEK-N-------------EKKMTRGGTPNYIAPEV----------
CDC5_Scer_PLK1                -NYNLKIGDFGLAAVLANES-------------ERKYTICGTPNYIAPEV----------
zyg-1_Cele_SAK                KKMTVKLGDFGLATTLGR-G-------------ETTCTIVGTPGFIAPQV----------
PLK_Ddis_PLK1                 -NMRIKLGDFGLSTKVEH-G-------------ERKKTICGTPNYIAPEI----------
8635_Tthe_SAK                 --GKIKIADFGLATKVNDEN-------------PECNTMCGTANYLSPEI----------
8635~b_Tthe_SAK               -GYLAKIIDFGEAYHPDVCNGKEFYNNQQRLIFKSYFLMKGNPNYKPGRT----------
18358b_Tthe_PLK-Unclassified  -KMEIKLGDFGLATKLEYDG-------------ERKRTICGTPNYIAPEI----------
18380_Tthe_PLK-Unclassified   -NMTLKIGDFGLATKIEYEG-------------EKKKTVCGTPNYIAPEI----------
21183_Tthe_SAK                -NNSVKICDFGLAVRVTNYE-------------SERDTFCGTPNYIAPEK----------
22503_Tthe_PLK-Unclassified   -KMVVKLADFGLSAMMKN-A-------------QKRKTVCGTPNYIAPEV----------
5034_Tthe_SAK                 -DHQVKICDFGLAVRLNGNE-------------QEKNTICGTPNYISPEI----------
8829_Tthe_PLK-Unclassified    -KMEIKLGDFGLATKLEFDG-------------EKKHTICGTPNYIAPEI----------
SAK_Spur_SAK                  -DMHCKIADFGLAAQLKLPE-------------EQHYTMCGTPNYISPEI----------
PLK1_Spur_PLK1                -NMELKVGDFGLATKVDFSG-------------ERKKTLCGTPNYIAPEV----------
PLK2_Spur_PLK2                -TMGVKIGDFGLAAKLEFEG-------------DRKRTMCGTPNYIAPEV----------
n1170_Tthe_PLK-Unclassified   -KMEIKLGDFGLATKLEFDG-------------EKKRTICGTPNYIAPEI----------
n808_Tthe_PLK-Unclassified    -KMEIKLGDFGLATKLEFDG-------------EKKRTICGTPNYIAPEI----------
CC1G_07437_Ccin_PLK1          -NMNVKVGDFGLAALIENPG-------------ERKKTICGTPNYIAPEV----------
AqueK200_Aque_PLK1            -DIEIKLGDFGLATRLEEDG-------------ERKKTLCGTPNYIAPEV----------
AqueK201_Aque_SAK             -SMDIKIADFGLSVTLDLPG-------------DKHHTLCGTPNYIAPYVICCYEGCFLI
GK066_Glam_PLK-Unclassified   -DFDVKVGDFGLAVKCETPE-------------ELHWTMCGTPNFLPSEV----------
                                   *: *:* :                           *...: .

PLK4_Hsap_SAK                 -------AT---------------------------------------RSAHGLESDVWS
PLK3_Hsap_PLK2                -------LL---------------------------------------RQGHGPEADVWS
PLK2_Hsap_PLK2                -------LN---------------------------------------KQGHGCESDIWA
PLK1_Hsap_PLK1                -------LS---------------------------------------KKGHSFEVDVWS
polo_Dmel_PLK1                -------LT---------------------------------------KKGHSFEVDIWS
SAK_Dmel_SAK                  -------VS---------------------------------------RTSHGLPADVWS
PLK5_Mmus_PLK2                -------VS---------------------------------------RNGHSCKSDIWA
PLK4_Mmus_SAK                 -------AT---------------------------------------RSAHGLESDIWS
PLK3_Mmus_PLK2                -------LL---------------------------------------RQGHGPEADVWS
PLK2_Mmus_PLK2                -------LN---------------------------------------KQGHGCESDIWA
PLK1_Mmus_PLK1                -------LS---------------------------------------KKGHSFEVDVWS
plk-2_Cele_PLK1               -------LN---------------------------------------KIGHSFEVDLWA
plk-1_Cele_PLK1               -------LN---------------------------------------KAGHSFEVDIWA
F55G1.8_Cele_PLK1             -------LN---------------------------------------ETGHAFEVDIWA
CDC5_Scer_PLK1                -------LMG-------------------------------------KHSGHSFEVDIWS
zyg-1_Cele_SAK                -------YD---------------------------------------Q-EYTQSADVYS
PLK_Ddis_PLK1                 -------LD--------------------------------------NSNGHSYEVDVWS
8635_Tthe_SAK                 -------LN---------------------------------------SKGYGKKTDIWS
8635~b_Tthe_SAK               -------LPYTPYSNNN------------------------------DRQASYKNLDIFS
18358b_Tthe_PLK-Unclassified  -------LEA-------------------------------------KETGHSYEVDVWS
18380_Tthe_PLK-Unclassified   -------LE--------------------------------------GKDGHSYEVDMWS
21183_Tthe_SAK                ---------------------------------------------------YGIQSDCWS
22503_Tthe_PLK-Unclassified   -------LK---------------------------------------NQGHDYLVDNWA
5034_Tthe_SAK                 -------LN---------------------------------------KQPYGMKIDCWS
8829_Tthe_PLK-Unclassified    -------LD--------------------------------------GKTGHSYQVDIWS
SAK_Spur_SAK                  -------AT---------------------------------------RGPHGLQSDVWS
PLK1_Spur_PLK1                -------LS---------------------------------------KKGHSYEVDLWS
PLK2_Spur_PLK2                -------LG---------------------------------------KIGHSFEADVWA
n1170_Tthe_PLK-Unclassified   -------LD--------------------------------------GRVGHSYEVDIWS
n808_Tthe_PLK-Unclassified    -------LD--------------------------------------GRVGHSYEVDIWS
CC1G_07437_Ccin_PLK1          -------LFD-------------------------------------TANGHSFEVDIWS
AqueK200_Aque_PLK1            -------LT---------------------------------------KKGHSYEVDIWS
AqueK201_Aque_SAK             FIFCREVAK---------------------------------------REAHGLESDIWS
GK066_Glam_PLK-Unclassified   -------IYS------HIMKRKASGRGPDPNLDEDCVNLCHQLLPAYSGQGHSFSADMWS
                                                                                      * ::

PLK4_Hsap_SAK                 LGCMFYTLLIGRPPFDTDT--VKN---TLNK-------VV-LAD--YEMPS--FLSIEAK
PLK3_Hsap_PLK2                LGCVMYTLLCGSPPFETAD--LKE---TYRC-------IK-QVH--YTLPAS--LSLPAR
PLK2_Hsap_PLK2                LGCVMYTMLLGRPPFETTN--LKE---TYRC-------IR-EAR--YTMPSS--LLAPAK
PLK1_Hsap_PLK1                IGCIMYTLLVGKPPFETSC--LKE---TYLR-------IK-KNE--YSIPKH--INPVAA
polo_Dmel_PLK1                IGCVMYTLLVGQPPFETKT--LKD---TYSK-------IK-KCE--YRVPSY--LRKPAA
SAK_Dmel_SAK                  VGCMLYTLLVGRPPFETDA--VQS---TLNK-------VV-MSE--YIMPA--HLSYEAQ
PLK5_Mmus_PLK2                LGCIMYTVLTGTPPFAAAP--LSE---MYQN-------IR-DGH--YLEPTH--LSPSAR
PLK4_Mmus_SAK                 LGCMFYTLLIGRPPFDTDT--VKN---TLNK-------VV-LAD--YEMPA--FLSREAQ
PLK3_Mmus_PLK2                LGCVMYTLLCGSPPFETAD--LKE---TYRC-------IK-QVH--YTLPAS--LSLPAR
PLK2_Mmus_PLK2                LGCVMYTMLLGRPPFETTN--LKE---TYRC-------IR-EAR--YTMPSS--LLAPAK
PLK1_Mmus_PLK1                IGCIMYTLLVGKPPFETSC--LKE---TYLR-------IK-KNE--YSIPKH--INPVAA
plk-2_Cele_PLK1               IGCILYILLFGHPPFESKS--LEE---TYSR-------IK-NNN--YVIPTS--ASAAAS
plk-1_Cele_PLK1               VGCILYILLFGQPPFESKS--LEE---TYSR-------IR-HNN--YTIPSI--ATQPAA
F55G1.8_Cele_PLK1             IGCILYVLLFGSPPFESRR--VQE---TYVR-------IK-NND--YVVPEN--ASPTAN
CDC5_Scer_PLK1                LGVMLYALLIGKPPFQARD--VNT---IYER-------IK-CRD--FSFPRDKPISDEGK
zyg-1_Cele_SAK                LGAVLYTMLTARNPPPK------------------------------GLPPTCGMSPNAA
PLK_Ddis_PLK1                 IGIILYTLLIGKPPFETSD--VKH---TYQR-------IK-QNQ--YSFPDEPIISHYGK
8635_Tthe_SAK                 FGCILYALCSGNLPFFSGN--PSQ---TIQN-------IK-EGK--WQLPQNI--SDNVK
8635~b_Tthe_SAK               FGMVLSEIVFDTYPVDFKRGALHKLEEKFSRGDIRGRLV-KNYQRH-FGPKH--IINLLH
18358b_Tthe_PLK-Unclassified  FGVIAYTLLIGKPPFETND--VKS---TYKK-------IR-TNE--YSFPEQIQISSAAK
18380_Tthe_PLK-Unclassified   LGVIIYTLLIGKPPFETKD--VRT---TYKR-------IK-MNN--YCFPEQIQISDNAK
21183_Tthe_SAK                FGCILYTIATGRPPFETVS--IQQ---TLKM-------LQKKNK--VEYPSHL--SKSLV
22503_Tthe_PLK-Unclassified   IGVIVYTFLIGKPPFEEKE--VEN---TLRN-------IK-ANR--YSFPENCTISKEAK
5034_Tthe_SAK                 FGCILYALIVGHPPFQGQD--IVQ---TLKK-------VT-SQEQFFELPNNI--SDNLK
8829_Tthe_PLK-Unclassified    LGVIIYTLLIGKPPFETPD--VKT---TYKK-------IR-NIS--YGFPENVPISDQAR
SAK_Spur_SAK                  LGCMLYTFLTGTPPFDTEA--VKT---TLNK-------VM-LAE--YIIPT--HISMEAK
PLK1_Spur_PLK1                LGCIMYTLLVGKPPFETQS--LKD---TYQR-------IK-RNE--YRVPSH--VSTPAR
PLK2_Spur_PLK2                LGCIMYTMLVGRPPFETSS--LKE---TYAR-------IK-HNK--YHFPET--LSPVAK
n1170_Tthe_PLK-Unclassified   LGVILYTLLIGKPPFETHD--VKT---TYRK-------IK-SNQ--YSFPDHAPIPDSAK
n808_Tthe_PLK-Unclassified    LGVILYTLLIGK------------------------------------------------
CC1G_07437_Ccin_PLK1          IGVILYTLVIGRPPFQTKE--VKE---IYKR-------IR-DNE--YEFPAERAISTAVK
AqueK200_Aque_PLK1            LGCILYTLLVGKPPFETKT--LKD---TYQR-------IK-RNE--YHIPHY--VGPEAR
AqueK201_Aque_SAK             LGCMVYTMLVGTPPFDTDD--VQS---TLDN-------VV-NGD--FDIPQ--YITTNCT
GK066_Glam_PLK-Unclassified   FGCLVFSMIYGRPPFEAAD--IKT---TYKR-------IV-RCD--FSFPGSISVSEDLK
                              .* :   .

PLK4_Hsap_SAK                 DLIHQLLRRNPADRLSLSSVLDHPFM
PLK3_Hsap_PLK2                QLLAAILRASPRDRPSIDQILRHDFF
PLK2_Hsap_PLK2                HLIASMLSKNPEDRPSLDDIIRHDFF
PLK1_Hsap_PLK1                SLIQKMLQTDPTARPTINELLNDEFF
polo_Dmel_PLK1                DMVIAMLQPNPESRPAIGQLLNFEFL
SAK_Dmel_SAK                  DLINKLLKKLPHERITLEAVLCHPFM
PLK5_Mmus_PLK2                SLIARLLAPDPAERPSLDHLLQDDFF
PLK4_Mmus_SAK                 DLIHQLLRRNPADRLSLSSVLDHPFM
PLK3_Mmus_PLK2                QLLAAILRASPRDRPSIEQILRHDFF
PLK2_Mmus_PLK2                HLIASMLSKNPEDRPSLDDIIRHDFF
PLK1_Mmus_PLK1                SLIQKMLQTDPTARPTIHELLNDEFF
plk-2_Cele_PLK1               QLIRVLLDPVPSRRPNARAVCRDHFF
plk-1_Cele_PLK1               SLIRKMLDPEPTRRPTAKQVIS---I
F55G1.8_Cele_PLK1             RLIRSLLDPVPDRRPTAEAVLLDQFF
CDC5_Scer_PLK1                ILIRDILSLDPIERPSLTEIMDYVWF
zyg-1_Cele_SAK                RLVEQMMDTDAKKRIPLTQIVLSEFM
PLK_Ddis_PLK1                 SLIISILNPVPEQRPNLTQILEHD-F
8635_Tthe_SAK                 DLLSNTLNWDQNSRFSIEQVLSHKFY
8635~b_Tthe_SAK               CLIFRCID-EKENRPTIDWII---LI
18358b_Tthe_PLK-Unclassified  NMIKKILTTDPSKRPTINELFNDDFF
18380_Tthe_PLK-Unclassified   SIITSILNLNPQKRLTLDELLEHPFM
21183_Tthe_SAK                DLIDHILDWNQDTRYNISQIKSHPFY
22503_Tthe_PLK-Unclassified   DFIQKILVPNPDQRLTMDQMLQHPFM
5034_Tthe_SAK                 DLLVNIINWNQDSRFTIDQILMHPFY
8829_Tthe_PLK-Unclassified    GLITRILNIDPQRRPTLDEIMSSSFL
SAK_Spur_SAK                  DLINKMLRKDPTERIGLSTVLDHPFM
PLK1_Spur_PLK1                NLIVKLLKNDPTQRPHIDILLQDEFF
PLK2_Spur_PLK2                EIISDLLSSDPEERPPLEVVIDHEFF
n1170_Tthe_PLK-Unclassified   ALIQLILQQDPAKRPTLDEILAHPFI
n808_Tthe_PLK-Unclassified    -------------------------N
CC1G_07437_Ccin_PLK1          VLIQQILTPDPSQRPTLHEIIEDTFF
AqueK200_Aque_PLK1            TLISNLLRPNPANRPTAAEILKDPFF
AqueK201_Aque_SAK             SLNL--HVYHPSKRLTLQQVLYHS-F
GK066_Glam_PLK-Unclassified   NFIKGLLTPDPRKRFTVKECLDHSWL