lok_Dmel MARDTQGTQGTQSQA-S------------------------------------NI-W---
CHK2_Mmus MKSHHQSHSSTSSKA-HDSASCSQSQGGFSQPQGTPSQLHELSQYQGSSSSSTGTVPSSS
chk-2_Cele MVRGTKRRRSSAEKP-I-----------------------------------VVVPVTRD
RAD53_Scer MENITQPTQQSTQAT-Q------------------------------------RFLIEKF
DUN1_Scer MSLSTKREHSGDVTD-------------------------------------SSFKRQQR
CHK2_Hsap MSRESDVEAQQSH----GSSACSQPHGSVTQSQGS------SSQSQGISSSSTSTMPNSS
T08D2.7_Cele MVRETKRRRSSAEKP-I------------------------------------VVPVTRD
FHAK1_Ddis MSQTNYIPSTPNK----------------------------------------STPPSEL
FHAK2_Ddis MFKDIQTQNSYS-DELYSSQIY------------------------------STQQPQQP
FHAK3_Ddis MDEATQRQDP--------------------------------------------------
FHAK4_Ddis MNSNKEETTADG-SV-------------------------------------STTEEQQQ
FHAK5_Ddis MDELTQANTLA-------------------------------------------------
Chk2_Spur MYESDMSTASAGGSA-S----------------------------------SSSIEPNST
CC1G_09319_Ccin MDDEFNEPMHHEAYD-G------------------------------------EE-EQQT
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque MDMSSCGPTLD-------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus Q-----------------------------------------------------------
chk-2_Cele DTMPVD------------------------------------------------------
RAD53_Scer SQEQIG------------------------------------------------------
DUN1_Scer SNKPSS------------------------------------------------------
CHK2_Hsap Q-----------------------------------------------------------
T08D2.7_Cele DTMPVD------------------------------------------------------
FHAK1_Ddis SSTPID------------------------------------------------------
FHAK2_Ddis QQQPQQQQSTFSSQQSQSSSYDFIYSTPQIHSQNSQNSQFSQNPLYDDFIHSTQNSYSQR
FHAK3_Ddis ----IE------------------------------------------------------
FHAK4_Ddis QQQPQQQEQINTTTA---------------------------------------------
FHAK5_Ddis ----I-------------------------------------------------------
Chk2_Spur S-----------------------------------------------------------
CC1G_09319_Ccin Q-----------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ---------------------------SS-----------------HSSSGTLSSLETVS
chk-2_Cele ------------------------------------------------------------
RAD53_Scer ------------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ---------------------------SS-----------------HSSSGTLSSLETVS
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis VSSQRSYSQKSSSSQISFSQIPSSQIQSSQIPSSQIHSSQIPSSQNQSSQKSQFSFSQIP
FHAK3_Ddis ------------------------------------------------------------
FHAK4_Ddis -----------STTSN--GENTASD-NNN-----------------NSNNNNNNNTNNTN
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur -----------------------SA-SAS-----------------LSSAGTLSSMETIP
CC1G_09319_Ccin -----------------------------------------------------------S
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque -------------------------------------------------------VSDLP
lok_Dmel ------------------------------------------------------------
CHK2_Mmus TQELCSI-----------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer ------------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap TQELYSI-----------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis ---SSQIPSSQKRFFQSQNDDFVPSSQVTSLQDICLPQPIQQQQQQQQQQQQQQQQQQQQ
FHAK3_Ddis ------------------------------------------------------------
FHAK4_Ddis TNNNCDI-----------------------------------------------------
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur TQEVA-------------------------------------------------------
CC1G_09319_Ccin TQEAS-------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque DTEVA-------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer ------------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis QQQQQQQQQQQQCQPQQQQTQQQQQQQQQQQQQQQQQQQQQQQQQQTQQQQQQPQEDDDD
FHAK3_Ddis ------------------------------------------------------------
FHAK4_Ddis ------------------------------------------------------------
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin ------------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel ----------------------------------------------------TQVESQP-
CHK2_Mmus ----------------------------------------------P-----EDQEPEE-
chk-2_Cele ----------------------------------------------------EDLVVGES
RAD53_Scer ----------------------------------------------------ENIVCRVI
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ----------------------------------------------PEDQEPEDQEPEE-
T08D2.7_Cele ----------------------------------------------------EDLVVEES
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis YDDYDGYDNYEDFVYNEGEEGEEDYEDYEQENDDDDDEDEDDDDDDDD--DDDDEEEEE-
FHAK3_Ddis ---------------------------------------------------ETDAEKKV-
FHAK4_Ddis ----------------------------------------------SM---TEDNSKEE-
FHAK5_Ddis ---------------------------------------------------DEDLVDSV-
Chk2_Spur ---------------------------------------------------EGDFDFAE-
CC1G_09319_Ccin -----------------------------------------------QS--QSQSPGQA-
AqueK082_Aque --------------------------------------------------------AEE-
AqueK083_Aque -----------------------------------------------VD--ETDGAAEE-
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele Q-----------------------------------------------------------
RAD53_Scer C-----------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele Q-----------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis ESQQQHIRSRALQSRSSQSRPLLRSGFKSPISRLSQTKTSPEYIYISSQSNTHTNQLGQS
FHAK3_Ddis ------------------------------------------------------------
FHAK4_Ddis DTGI--------------------------------------------------------
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin ------------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer ------------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis SQQTNSPNVHFNSLQQKKKQQQQQQQQQQQQQQQQQQQQQQQQQQQSQQIIGSQSSQSSQ
FHAK3_Ddis ------------------------------------------------------------
FHAK4_Ddis ------------------------------------------------KV----------
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin ------------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel --------MEKIVWGRLYGKN-IKI-K---------------------------------
CHK2_Mmus --------PGPAPWARLWALQ-DGF-S---------------------------------
chk-2_Cele -------CAASKPFAKLVGVR-RGI-S---------------------------------
RAD53_Scer -------TTGQIPI---RDLS-ADI-SQVLK-----------------------------
DUN1_Scer ---------EYTCLGHLVNLI-PGKEQ---------------------------------
CHK2_Hsap --------PTPAPWARLWALQ-DGF-A---NLETESGHVTQSDLELLLSSDPPASASQSA
T08D2.7_Cele -------CAALKPFAKLVGVR-RGI-S---------------------------------
FHAK1_Ddis ---------E-NDIGLLVSLN-QEISS---------------------------------
FHAK2_Ddis LPPTQPPVEVPVNLGRLIPIN-ASH-I---------------------------------
FHAK3_Ddis -------QVVPSLWGRLVSNH-PES-R---------------------------------
FHAK4_Ddis -------IGEGELWGKLISLN-PTY-P---------------------------------
FHAK5_Ddis --------NSVKGWGILKSLN-PSY-P---------------------------------
Chk2_Spur --------ERVVVWGRLYPVG-KCF-S---------------------------------
CC1G_09319_Ccin --------VDAHLWGYLQPVN-DKL-I---------------------------------
AqueK082_Aque --------QSLEIWGRFFPLPRAGL-T---------------------------------
AqueK083_Aque --------QSLEIWGRFFPLPRAGL-T---------------------------------
lok_Dmel -------------SLDLN---NDEFTAGRGEA-NDLI-L--TLNDLP-E-KILTRISKVH
CHK2_Mmus -------------NLDCV---NDNYWFGRDKS-CEYC-F--DGPLLR-RTDKYRTYSKKH
chk-2_Cele -------------SIDL---ADDHFVCGRGSDDAPTN-F--NFSQVAKDVGLYRFISKIQ
RAD53_Scer -------------EKRS---IKKVWTFGRNPA-CDYH-L--GN---------ISRLSNKH
DUN1_Scer -------------K--VEITNRNVTTIGRSRS-CDVI-L--SEP----------DISTFH
CHK2_Hsap GIRGVRHHPRPVCSLKCV---NDNYWFGRDKS-CEYC-F--DEPLLK-RTDKYRTYSKKH
T08D2.7_Cele -------------SIDL---ADDHFVCGRGSHDAPTN-F--NFSTVAEDVGLYKFISKIQ
FHAK1_Ddis -------------NIHVKIKIEENITIGRSKT-CNIV-V--PEL----------IVSGKH
FHAK2_Ddis -------------PINLNLKREDRIVVGRSSS-CDAR-LIDNYL----------TISGKH
FHAK3_Ddis -------------HIDL---IEHSIFFGRNPKRCQVV-L--HDP----------TVSGIH
FHAK4_Ddis -------------TIEI---RQDSIILGRSKGVCNYT-F--TSP----------TVSGKH
FHAK5_Ddis -------------DISL---VENVITFGRLKD-STVH-Y--NDK----------SISGSH
Chk2_Spur -------------SIDFL-DTKDEYIFGRDPS-CDVC-Y--NGPEIS-KNPCYQTLSKTH
CC1G_09319_Ccin -------------RIDFW-RAEPSYTIGRNTT-CNRIIF--PGF----------KVSNKH
AqueK082_Aque -------------GIDFL---DDEYIFGRSED-CDYC-F--ERRGGT-SNQHYPTYSSTH
AqueK083_Aque -------------GIDFS---DDEYIFGRSED-CDYC-F--ERRGGT-SNQHYPTYSSTH
** * :
lok_Dmel FIIKRANC--------------------------------------------------EL
CHK2_Mmus FRIFREMG-------------------------------------------------PKN
chk-2_Cele FSIDRD----------------------------------------------------TE
RAD53_Scer FQILLG-----------------------------------------------------E
DUN1_Scer AEFHLLQM----------------------------------------------DVDNFQ
CHK2_Hsap FRIFREVG-------------------------------------------------PKN
T08D2.7_Cele FSIDRD----------------------------------------------------TE
FHAK1_Ddis CIITRADAI---------------------------------------------ENGNTN
FHAK2_Ddis CEIYRADNLTCLK--HIPLC-------------------------------KDKTDCHKN
FHAK3_Ddis CRIFREEIPCQKYNNNNNNDGDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTK
FHAK4_Ddis CKIYRDP------------------------------------------------TVKS-
FHAK5_Ddis CKITRES------------------------------------------------NDDDG
Chk2_Spur FRIFKESN--------------------------------------------------DN
CC1G_09319_Ccin CTITWNGS-------------------------------------------------DSN
AqueK082_Aque FRIYRERS-----------------------------------------------KTDSN
AqueK083_Aque FRIYRERS-----------------------------------------------KTDSN
:
lok_Dmel TNPVYIQDLSRNGTFVNNEKIGTNRMRILKNDDVISLSHPTY--------K----AFVFK
CHK2_Mmus CYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRN--------K----VFVFF
chk-2_Cele TRRIYLHDHSRNGTLVNQEMIGKGLSRELMNGDLISIGIPAL--------I----IFVYE
RAD53_Scer DGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESD------ILSLVIFIND
DUN1_Scer RNLINVIDKSRNGTFINGNRLVK-KDYILKNGDRIVFGKSCSF------------LFKYA
CHK2_Hsap SYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRN--------K----VFVFF
T08D2.7_Cele TRRIYLHDHSRNGTLVNHEMIGKGLSRELMNGDLISIAIPAL--------I----IFVYE
FHAK1_Ddis YGLLMIQDQSTNGTFINGKLIGKGKSRLLKNGDKLCLGKSTKEI-----DI----SFLYK
FHAK2_Ddis FGMLIVHDISSNGSYINGELIGNGKTRILRSDDILSLGHPSG-------DL----KFIFE
FHAK3_Ddis NYITKITDTSSNGTFVKGCILGKDKTTIIQNGDMVSFTSAKLIS-----SL----SFTFL
FHAK4_Ddis RNVAFVDDTSTNGTFINNEVIGKGSKILIENGCEISVIPKKGSE-----KI----SFIYQ
FHAK5_Ddis VVIAFIYDNSTNGTFIDNIKVGKGSRCLLASGQEISLTPQKQLE-----KI----AYIFQ
Chk2_Spur CNFYFIEDKSSNGTFVNGEKIGKGKKQVLNNNDEIALSLSKN--------K----AYVFM
CC1G_09319_Ccin -GSVVVLDLSSNGTFINGSKIGKNNSRILRDGNEIAFGTPSPQPNNPHEDY----RFIYR
AqueK082_Aque QFVVFLQDKSSNGTFINGDKIGKNKTHILNNDDEISLSVKNN--------K----VFVFN
AqueK083_Aque QFVVFLQDKSSNGTFINGDKIGKNKTHILNNDDEISLSVKNN--------K----VFVFN
: * * **: :. : . : .. : . :
lok_Dmel DLS--------PN-----------------------------------------------
CHK2_Mmus DLT--------VD-----------------------------------------------
chk-2_Cele SAD---------------------------------------------------------
RAD53_Scer KFK--------QCLEQNKVDRI---------------------RSNLKNTSKIASPGLTS
DUN1_Scer SSS--------STDIENDDEKVSSESRSYKNDDEVFKKPQISATSSQN-ATTSAAIR---
CHK2_Hsap DLT--------VD-----------------------------------------------
T08D2.7_Cele RAD---------------------------------------------------------
FHAK1_Ddis SNY--------SNQLLLSS-----------------------STNNLNNSGTAQYI----
FHAK2_Ddis SEFQFNFILDIKDNVNNLNENLDYK--------K------L----------RTAYDN---
FHAK3_Ddis DLT--------NP-----------------------------------------------
FHAK4_Ddis DCF--------EE-----------------------------------------------
FHAK5_Ddis TVE---------------------------------------------------------
Chk2_Spur DTK--------DS-----------------------------------------------
CC1G_09319_Ccin HA----------------------------------------------------------
AqueK082_Aque DRS--------VS-----------------------------------------------
AqueK083_Aque DRS--------VS-----------------------------------------------
lok_Dmel ---ESI-GLPEEINKTYY-VNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPS
CHK2_Mmus ---DQS-VYPKELRDEYI-MSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALG-SS
chk-2_Cele ----A-DHHPEELTKKYHVTSHSLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFS-TRCS-
RAD53_Scer STASSMVANKTGIFKDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKV-IGN--
DUN1_Scer ---KLNKTRPVSFFDKYL-LGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQN-DDQ-K
CHK2_Hsap ---DQS-VYPKALRDEYI-MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIG-SA
T08D2.7_Cele ----D-NHHPEELTNKYHVTSHLLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFS-TRCS-
FHAK1_Ddis ---WERKDIKDDILKDYD-FIKELGSGNFSVVYEGVNKNTGKRVAIKHLNLSKINTHTPK
FHAK2_Ddis ---ARIENKNCALRD-YY-FVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGST-SK
FHAK3_Ddis ---YIDEPFEEEMNKKYS-IQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQ-TK
FHAK4_Ddis ---Q-KEMEQGGPQQKYD-LREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMT-SK
FHAK5_Ddis -----KEIEDGGPSNKYF-IGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSA
Chk2_Spur ---DQS-NLPEALREKFI-MSKVLGRGACGQVKLAFEKGTCRKVAVKIIEKKTFSIG-GT
CC1G_09319_Ccin ----ANGPPTTGLYAYYD-VSTELGKGSFATVMKAVNRKTGVWYAVKMIKDKRAAHA-GD
AqueK082_Aque ---EQNNN-LPEFKDKYT-MSKQIGKGACGIVKLAFHRETCKGYAIKIISKKMFSVG-PH
AqueK083_Aque ---EQNNNLPEEFKDKYT-MSKQIGKGACGIVKLAFHRETCKGYAVKIISKKMFSVG-PH
: :* * . * *:* .
lok_Dmel TNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDK-----PDSVYMVLEFMRGGDLLNRIIS
CHK2_Mmus READTAPSVETEIEILKKLNHPCIIKIKDVFDA-----E-DYYIVLELMEGGELFDRVVG
chk-2_Cele RAIAKTRDIRNEVEVMKKLSHPNIVAIYDWITV-----AKYSYMVIEYVGGGEFFSKVVD
RAD53_Scer -----MDGVTRELEVLQKLNHPRIVRLKGFYED-----TESYYMVMEFVSGGDLMDFVAA
DUN1_Scer ----KNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVR
CHK2_Hsap READPALNVETEIEILKKLNHPCIIKIKNFFDA-----E-DYYIVLELMEGGELFDKVVG
T08D2.7_Cele RAIAKTRDIQNEVEVMKKLSHPNIVAIYDCITV-----AKYSYMVIEYVGGGEFFSKLVD
FHAK1_Ddis ----FKSQLNREIEILKFINHENVVEIYDIFYT----KDQQLFFILELANGGELYNKIGF
FHAK2_Ddis ----SMELVSKEYNALKNIKHRNVIEFFDIVFS-----STDCFFIVELATN-DL-SNLLR
FHAK3_Ddis ----TRRQMESEVEILQKIKHPNIISIIDIVQS-----DRYFYIVLELATGGELFEKIKQ
FHAK4_Ddis ----RKDSLMDEVNVLTKVKHQNIISIKEVFET-----QKNLYLVLELVTGGELFDKIVS
FHAK5_Ddis ----RKDSLMDEVNILRGLSHPNIIQIIEVFEN-----EKVLSLILELVECGELLNDIVS
Chk2_Spur MVRNMEKTVMEEVRILKRLHHPCIIGIEDVCDT-----PEVLYIVLELVESGELFDRVVS
CC1G_09319_Ccin I---RNSAIAREISIMEKLKHRNICELKEVFME---EGSSDINLVLELVEGGDLLEYILN
AqueK082_Aque ----LGRAAMEEVKIIKALQHPCIIRVEDLYES-----TDSLYIVLELVEGGELFDRVIL
AqueK083_Aque ----LGRAAMEEVKIIKALQHPCIIRVEDLYES-----TDSLYIVLELVEGGELFDRVIL
* : : * : . :::* :: . :
lok_Dmel N----KLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLETN-------------
CHK2_Mmus N----KRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQ-------------
chk-2_Cele SKYNRMGLGESLGKYFAFQLIDAILYLHSVGICHRDIKPENILCSDK-------------
RAD53_Scer HG----AVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQ--------------
DUN1_Scer K----TCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPW
CHK2_Hsap N----KRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-------------
T08D2.7_Cele SKYNQMGLGESLGKYFAFQLIDAVLYLHSVGICHRDIKPENILCSNK-------------
FHAK1_Ddis NE---PLLNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYG------------
FHAK2_Ddis K----RCVDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEF-------------
FHAK3_Ddis K----GRFSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVS------------
FHAK4_Ddis E----RKFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLAT--------------
FHAK5_Ddis N----LFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKN------------
Chk2_Spur L----GKFDEATAKFYFYQMITACKYLHDNGITHRDLKPENLLLMSD-------------
CC1G_09319_Ccin R----GGLSEVDAKHITHQICSALSYIHQQGIAHRDLKPENVLLTKS-------------
AqueK082_Aque N----GKFNDKVGKLLFYQMVVAVKYLHDKGITHRDLKPENILLSST-------------
AqueK083_Aque N----GKFNDKVGKLLFYQMVVAVKYLHDKGITHRDLKPENILLSST-------------
: : *: . *:*. .* ***:**:*:*
lok_Dmel ---DEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITG----------------
CHK2_Mmus ---EEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLVSN----------------
chk-2_Cele ---AERCILKLTDFGMAKN--SVNRMKTRCGTPSYNAPEIVANEG---------------
RAD53_Scer ---DDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSV--SP--------
DUN1_Scer DEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTK-----------------
CHK2_Hsap ---EEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSV----------------
T08D2.7_Cele ---AERCILKLTDFGMAKN--SVNRMKTHCGTPSYCAPEIVANQG---------------
FHAK1_Ddis ---DDYLKIKITDFGLARFIHEGELAKTLCGSPLYVAPEVILSLHHKNKYGTNSSSSSQS
FHAK2_Ddis ---KQGFSIKITDFGLSSFVEESQYLQTFCGTPLFFAPEVIANNF---------------
FHAK3_Ddis --HGKSSVIKVTDFGLAKIIGEKEMATTLCGTPLYVAPEIIRNCLHGD--G---------
FHAK4_Ddis ---PNSFLLKISDFGLSRAMDEGTYMKTMCGTPQYVAPEILTKG----------------
FHAK5_Ddis --FNQNDAIKLTDFGLSRTVSDGSFMKTMCGTPQYLAPEILTSSG---------------
Chk2_Spur ---DKETILKVTDFGLSKFVGEQSLMKTLCGTPTYLAPEILTSM----------------
CC1G_09319_Ccin ----NPPVVKVADFGLAKIVDSLTMLRTMCGTPSYLAPEVVKQV----------------
AqueK082_Aque ---DEETLIKVTDFGLSKFVGEQSLMKTLCGTPSYLAPEVLWSA----------------
AqueK083_Aque ---DEETLIKVTDFGLSKFVGEQSLMKTLCGTPSYLAPEVIKSA----------------
:*::*** : . * **: : ***::
lok_Dmel -----GREAYTKKVDIWSLGVVLFTCLSGTLPFSDEY----GT-PAAQQIKKGRFAYGHP
CHK2_Mmus -----GTAGYSRAVDCWSLGVILFICLSGYPPFSEHK----TQVSLKDQITSGKYNFIPE
chk-2_Cele -------VEYTPKVDIWSLGCVLFITFSGYPPFSEEY----TDMTMDEQVLTGRLIFH-A
RAD53_Scer -DEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGST----Q-DQLYKQIGRGSYHEGPL
DUN1_Scer -------KGYTSKVDLWSAGVILYVCLCGFPPFSDQL----GPPSLKEQILQAKYAFYSP
CHK2_Hsap -----GTAGYNRAVDCWSLGVILFICLSGYPPFSEHR----TQVSLKDQITSGKYNFIPE
T08D2.7_Cele -------VEYTPKVDIWSLGCVLFITFSGYPPFSEEY----TDLKMDEQVLTGRLFFH-E
FHAK1_Ddis PTKDINSVGYGKSCDAWSLGAILYIVLCGTPPFDDDDDEEMSTPQLFEKIVSGNYRVEKL
FHAK2_Ddis -----FSNGYGKSCDLWSIGVTLYLSLCKYKPFIVDC----R--DLYHSFINGNLGFTSK
FHAK3_Ddis --GAQVNTGYGKEVDVWSLGCILYILLSGRPPFDFDH----TNNFNLKLINQGLYNFSLP
FHAK4_Ddis -----EREGYGKSVDLWSIGVITYILLCGFPPFGDPQ-----TKDFFEKIKNGGFSFPSP
FHAK5_Ddis -----GHNGYGLEVDCWSMGAILYIMLCGYPPFDDSR-----EVSIFEQIRNAKFEFDPE
Chk2_Spur -----GMGGYTKAVDCWSIGVILYICLAGYPPFSDEI----KAMNLDEQIKRGYYSFPTK
CC1G_09319_Ccin -----NQEGYDNLVDSWSVGVIVFSMLTNASPFIEDE----TQRDIRTRIAERRIDWSVL
AqueK082_Aque -----GLGGYSKAVDCWSLGVILYIMLGGYPPFSDEI----REHSLHDQICQGIYSFPPA
AqueK083_Aque -----GLGGYSKAVDCWSLGVILYIMLGGYPPFSDEI----REHSLHDQICQGIYSFPPA
* * ** * : : ** .
lok_Dmel SWKSVSQRA--KLLINQMLIVDPERRPSIDDVLQSSWLRDAPMLQKAKRLMKLDGME---
CHK2_Mmus VWTDVSEEA--LDLVKKLLVVDPKARLTTEEALNHPWLQDEYMKKKFQDLLVQEKNS---
chk-2_Cele QWRRITVET--QNMIKWMLTVEPSNRPSAVELMSTQWMKCADCRTAKQ------------
RAD53_Scer KDFRISEEA--RDFIDSLLQVDPNNRSTAAKALNHPWIKMSPLGSQSYGDFSQISLSQSL
DUN1_Scer YWDKIDDSV--LHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVS--LELQR-----
CHK2_Hsap VWAEVSEKA--LDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENES---
T08D2.7_Cele QWHRITDET--QNMIQWMLTVEPLIRPSAVELMSTQWMKCADCLSAKQ------------
FHAK1_Ddis EKSLISSSA--ADLVKGLLTVDPDKRLTVEQALNHPWITEINNNSNNNN-NNINN-----
FHAK2_Ddis KWAKISNYA--KDLVRRLLVIDPEHRITIKEALNHPWFTQDRRFFKK--YPKHYKSRAQP
FHAK3_Ddis VWDVVTENA--KDLIKKLLNVDPTKRISTKGALSHDWFNDDDLLRCSTVIANQSPISKSP
FHAK4_Ddis YWDEISDEA--KSLIKNLIKVDVEKRFTIDQALNHPWFTNHEEKTKE--FYEKDK-----
FHAK5_Ddis DWSSVSEEA--KDLIKRLLCVDPHKRYTCNNIIQHPWFNPNVKLSTL--LEEDERLRKKA
Chk2_Spur YWGSVSAPDVFIRMVRWISIL------------------------------KCPNDA---
CC1G_09319_Ccin EAQNPSAEC--IHFIRSLLQEDPSVRMSLTQALDHPWLQSYIPVHQSQDQYLLAGVS---
AqueK082_Aque YWNGVSKD------------VDSSKRWTTAQALEHTWLKDEDMRRKAHQMMVETADK---
AqueK083_Aque YWNGVSKDG--IDLIEKLLTVDSSKRWTSAQALEHTWLKDEDMRKKAHQMMMETADK---
lok_Dmel -----------------------IE---------------------E-------------
CHK2_Mmus -----------------------VT---------------------LPV---------AP
chk-2_Cele ------------------------------------------------------------
RAD53_Scer SQQ-KLLENMDDAQYEFVKAQRKLQMEQQLQEQDQEDQDGKIQGFKIPAHAPIRYT--QP
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap -----------------------TA---------------------LPQ---------VL
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis -KTQFF-----------------VE---------------------CFN-----------
FHAK3_Ddis QRSHGV-----------------VQ---------------------LPVVDVKSKN--IP
FHAK4_Ddis -----------------------LE---------------------FPPPSTNDDHQPTP
FHAK5_Ddis E---AE-----------------VE---------------------ANNNNTNK--SNSP
Chk2_Spur -----------------------KL---------------------I-----------G-
CC1G_09319_Ccin ------------------------S---------------------SPD-------VTSP
AqueK082_Aque -----------------------HQ---------------------MPP----------P
AqueK083_Aque -----------------------HQ---------------------MPP----------P
lok_Dmel ------------------------------------------------------------
CHK2_Mmus A-----------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer KSIEA-------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap A-----------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------------------------------------------------------------
FHAK2_Ddis ------------------VYYDLKSETGFICF------------------------REHF
FHAK3_Ddis MTLNS-------------------------------------------------------
FHAK4_Ddis NTTSSNS-----------------------------------------------------
FHAK5_Ddis KMLGKRKSEDGNCSDSNNNNNSGSKSLSS-------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin S--------------------------AGVSHDFIGLQIQPSAPRREGSRGAPLQRRSH-
AqueK082_Aque S-----------------------------------------------------------
AqueK083_Aque S-----------------------------------------------------------
lok_Dmel --------------------------------E---------------------------
CHK2_Mmus ------------------------------QT-S--------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer -------------------------------ETRE-Q-----KLLHSNNTENVKSSKKKG
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------QPST--------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ---------------------------------------------------------NSS
FHAK2_Ddis DNLETNYALFK-----------------QNFDNNNNNNNNNNNNNNNNNNNNNNNNNINN
FHAK3_Ddis -------------------------------TTT-NT-----TSPNNNNNNNNNNNNKNN
FHAK4_Ddis ----------------------------QLVPESKCDQIQD-----NTT-----------
FHAK5_Ddis --IKSNTTMLD-CDEKSNNNNNNGHKKSKSDPTSNNSLFNNDNNNNNNNNNNNNNNNNNN
Chk2_Spur -------------------------------PD---------------------------
CC1G_09319_Ccin --------VLSQAAEEGR-----PVPEP--SPEM----IA--------------------
AqueK082_Aque ------------------------------LP----------------------------
AqueK083_Aque ------------------------------LP----------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer NGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDN--RLSRVHCFIFKKRHA
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis NINI---------IKKS---------------------PLKTV--NT-------------
FHAK2_Ddis NNNN---------INNN---------------------NINNN--N--------------
FHAK3_Ddis NKNI---------IKSL---------------------NSNSN--N--------------
FHAK4_Ddis ------------------------------------------------------------
FHAK5_Ddis NN--------------------------------------N-NNNNN-------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin ------------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer VGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIG
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis -------------------------NNN-NNN----------------------------
FHAK2_Ddis -------------------------NNN-NNNN---------------------------
FHAK3_Ddis -------------------------YNN-NSVL---------------------------
FHAK4_Ddis ------------------------------------------------------------
FHAK5_Ddis -------------------------NN---------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin ------------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ------------------------------------------DIL---------------
RAD53_Scer FKVEINDTTGLFNEGLGMLQEQRV--VLKQTAEEKDLVKKLTQMMAAQRANQPSASSSSM
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ------------------------------------------DIL---------------
FHAK1_Ddis -------------------CK--LSSPIKNSS----------------------------
FHAK2_Ddis -------------------NNT-NTNNINNN-----------------------------
FHAK3_Ddis -------------------KKT-SQSPKTKSN----------------------------
FHAK4_Ddis ------------------------------------------------------------
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin ------------------------------------------------------------
AqueK082_Aque ------------------------------------------------------------
AqueK083_Aque ------------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus -SQK--------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer SAKK--------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap -SRK--------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis -KLK--------------------------------------------------------
FHAK2_Ddis -----------NNNYNNSHNHNNNNHNHNHNLNNHNHNNNHHHNHNHNHNHNHNHNHNHN
FHAK3_Ddis -RPKLQFEQPSP------------------------------------------------
FHAK4_Ddis ------------------------------------------------------------
FHAK5_Ddis ------------------------------------------------------------
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin -QAT--------------------------------------------------------
AqueK082_Aque -GSK--------------------------------------------------------
AqueK083_Aque -GSK--------------------------------------------------------
lok_Dmel ------------------------------------------------------------
CHK2_Mmus --------------RPL-ELE--VEGMPSTK-----------------------------
chk-2_Cele --------------------------------------------------KSIKPISAA-
RAD53_Scer --------------PPV-SDT--NNNGNNSVLNDLVESPI--NANTGNILKRIHSVSLSQ
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap --------------RPR-EGE--AEGAETTK-----------------------------
T08D2.7_Cele --------------------------------------------------KSIQPISA--
FHAK1_Ddis --------------RNL-SNEPLNNNISNNNNTQTSFTG---SLL--------------N
FHAK2_Ddis HNHNHNHNHNNHNNNNN-NNNNNNNNNNNNNNNNNNNNNNN-NN----------------
FHAK3_Ddis ---------NQHNNNNN-NNNNNNNNNNNNNNNNNSSGGKP-AII--------------N
FHAK4_Ddis ------------D-NNN-NNNNNNNNNNNNNNNNTTNNSN--NID--------------N
FHAK5_Ddis ------------NNNNNNNNNNNNNNNNNNNNNNNSNDTTDSDTD--------------D
Chk2_Spur ----------------------------N-------------------------------
CC1G_09319_Ccin --------------RSP-RDQ--TKRNKRV-RGNLTPLQE--ESD--------------A
AqueK082_Aque --------------RIL-NDE--NNNNGDSKRPHLEGTPS--PSD--------------D
AqueK083_Aque --------------RIL-NDE--NNNNGDSKRPHLEGTPS--PSD--------------D
lok_Dmel ------------------------------------------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ------------------------------------------------------------
RAD53_Scer ------------------------------------------------------------
DUN1_Scer ------------------------------------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ------------------------------------------------------------
FHAK1_Ddis ------Q-----------------------------------------------------
FHAK2_Ddis -------N----------------------------------------------------
FHAK3_Ddis ------NNGNLYSKFMATNNDPFDCTPTSTPVKPITNSTTTSTATSMPTSNSVTMGTSST
FHAK4_Ddis ------N-----------------------------------------------------
FHAK5_Ddis ------E---------------------------------------------------TI
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin SGSSGNRAGS--------------------------------------------------
AqueK082_Aque ------TI----------------------------------------------------
AqueK083_Aque ------TI----------------------------------------------------
lok_Dmel --------------------------------------------N---------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ----------------------------AP------A-------AL--------------
RAD53_Scer ---------------SQ----------IDPSKKVKRA-------KL--------------
DUN1_Scer ---------------LQ----------ITD------------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ----------------------------AP------A-------AL--------------
FHAK1_Ddis ---------------LQ----------LNEGELLKKR-------KTF-LSNNDQK-----
FHAK2_Ddis -----------------------------------------------N----NNNNNNNN
FHAK3_Ddis SIPVSNSITMKSPSILALSDDGDKKRKEKESSSSENVNDVIVIN----SNNHNNNNNNN-
FHAK4_Ddis ------------------------NG-NDESKSSKKR-------QLSEDSNIND------
FHAK5_Ddis SLPVITK-NSKSMSNLQNHLNNNKINSDDESETSTNNNN----NNNNNNNNNNNNNNNN-
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin -------S--------S-----------SNGKANKRP-------RL--------------
AqueK082_Aque ----------------S-----------IDTEPIARD-------Q---------------
AqueK083_Aque ----------------S-----------IDTEPIARD-------Q---------------
lok_Dmel -----------------------------------F------------------------
CHK2_Mmus ------------------------------------------------------------
chk-2_Cele ---------------------------------QTT------------------------
RAD53_Scer ---------------------------------DQT------------------------
DUN1_Scer ---------------------------------NKI------------------------
CHK2_Hsap ------------------------------------------------------------
T08D2.7_Cele ---------------------------------QTT------------------------
FHAK1_Ddis ----------ENI--------------------NPV------------------------
FHAK2_Ddis YYNNNINNINNNINNNI-------------NNNNNY------------------------
FHAK3_Ddis ----------HNINNGI-------------SSK---------------------------
FHAK4_Ddis ------------------------------------------------------------
FHAK5_Ddis ----NNNNKPSTINNNFPVPFPKSPTKNSPNASPPIKPQNSSNNNSGLAGIDKPKCQYDP
Chk2_Spur ------------------------------------------------------------
CC1G_09319_Ccin -----------------------------------R------------------------
AqueK082_Aque -----------------------------------S------------------------
AqueK083_Aque -----------------------------------S------------------------
lok_Dmel -----------LEPPTKRSRR
CHK2_Mmus ------------RLSVCGAVL
chk-2_Cele -----------QAGPVKKAKM
RAD53_Scer -----------SKGPENLQFS
DUN1_Scer -----------PKTYSELSCL
CHK2_Hsap ------------RPAVCAAVL
T08D2.7_Cele ----------------QAGPV
FHAK1_Ddis -----------INNPFLKSSQ
FHAK2_Ddis -----------HQQYTQHTTM
FHAK3_Ddis ------------PPPKRLKGS
FHAK4_Ddis ------------EHEQKKVKN
FHAK5_Ddis NCYRKNPQHLRDFYHTVSSNK
Chk2_Spur ------------IVGRLAEGR
CC1G_09319_Ccin -----------SAADDDSDYD
AqueK082_Aque -----------FTSNPDTNNS
AqueK083_Aque -----------FTSNPDTNNS