Trio_Hsap       YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGL
Trad_Hsap       YTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITL
SPEG_Hsap       YDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYF
SPEG~b_Hsap     YTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSL
Obscn_Hsap      YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRERDILAALSHPLVTGL
Obscn~b_Hsap    FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAVLREYEALKGLRHPHLAQL
Obscn_Mmus      YDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGL
Obscn~b_Mmus    FAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQL
SPEG_Mmus       YDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHGCVLYF
SPEG~b_Mmus     YTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERLMSL
Trad_Mmus       YTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYVTL
Trio_Mmus       YSEVAELGRGRFAVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQNLQHPLLVSL
Trad_Spur       FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLEQVQHEASMMQPLQHPLICSL
                :    :  ** *.  :   .       ..*::         . :*   :  * *     :

Trio_Hsap       LDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLD
Trad_Hsap       HDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLD
SPEG_Hsap       HEAFERRRGLVIVTELCT-EELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLD
SPEG~b_Hsap     HEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLD
Obscn_Hsap      LDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLD
Obscn~b_Hsap    HAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQHILHLD
Obscn_Mmus      LDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLD
Obscn~b_Mmus    HAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLD
SPEG_Mmus       HEAFERRRGLVIVTELCT-EELLERMARKPTVCESETRTYMRQVLEGICYLHQSHVLHLD
SPEG~b_Mmus     HEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLD
Trad_Mmus       HDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLD
Trio_Mmus       LDTFETPTSYVLVLEMADQGRLLDCVVRWGSLTEGKVRAHLGEVLEAVRYLHNCRIAHLD
Trad_Spur       HATYETHGQYILVLDLIPDGRILEYLVSLSQVTERQVIGFIRQLVQAVNYLHSNGIIHLD
                   :      ::: :     .:*  :       * .   .: :::..  ***   : ***

Trio_Hsap       LKPENILVDE-SLAKPTIKLADFGDAVQLNTTY--YIHQLLGNPEFAAPEIILGNPVSLT
Trad_Hsap       IKPENLLIDL-RIPVPRVKLIDLEDAVQISGHF--HIHHLLGNPEFAAPEVIQGIPVSLG
SPEG_Hsap       VKPENLLVWDGAAGEQQVRICDFGNAQELTPGE--PQYCQYGTPEFVAPEIVNQSPVSGV
SPEG~b_Hsap     IKPDNLLLAP----DNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSA
Obscn_Hsap      IKPSNILMVH--PAREDIKICDFGFAQNITPAE--LQFSQYGSPEFVSPEIIQQNPVSEA
Obscn~b_Hsap    LRSENMIITE----YNLLKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLEGQGAVPQ
Obscn_Mmus      IKPPNILMVH--PAREDIKICDFGFAQKITPSE--PQYSKYGSPEFVSPEIIEQNPVSEG
Obscn~b_Mmus    LRSENMMVTE----YNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQ
SPEG_Mmus       VKPENLLVWDGAGGEEQVRICDFGNAQELTPGE--PQYCQYGTPEFVAPEIVNQSPVSGV
SPEG~b_Mmus     IKPDNLLLAA----DNALKIVDFGSAQPYNPQALKPLGHRTGTLEFMAPEMVKGDPIGSA
Trad_Mmus       IKPENLLIDL-RIPVPRVKLIDLEDAVQISGHF--HIHHLLGNPEFAAPEVIQGIPVSLG
Trio_Mmus       LKPENILVDQ-SLAKPTIKLADFGDAVQLNTTY--YIHQLLGNPEFAAPEIILGNPVSLT
Trad_Spur       IKPENVMMEK-ALGRAQIKLIDFGDAMDLWSSPPPFYHELNANPEFCSPELLGGNEIDYG
                ::. *:::         ::: *:  *                  *  :**::

Trio_Hsap       SDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQ
Trad_Hsap       TDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQ
SPEG_Hsap       TDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLV
SPEG~b_Hsap     TDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAF-QLYPNTSQSATLFLRKVLS
Obscn_Hsap      SDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQ
Obscn~b_Hsap    TDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRLS-RCYAGLSGGAVAFLRSTLC
Obscn_Mmus      SDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQ
Obscn~b_Mmus    TDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLS-RCYAGLSGGAVAFLQSSLC
SPEG_Mmus       TDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLV
SPEG~b_Mmus     TDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAF-QLYPNTSQSATLFLRKVLS
Trad_Mmus       TDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQ
Trio_Mmus       ADTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPEDYFQGVSQKAKEFVCFLLQ
Trad_Spur       TDVWSIGALSYVMLSGISPFLDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLH
                :* *  *. ::: *:   *    . .     :               *  *  *:   *

Trio_Hsap       EDPAKRPSAALALQEQWL
Trad_Hsap       EDFRRRPTAATCLQHPWL
SPEG_Hsap       QD-RLRPTAEETLEHPWF
SPEG~b_Hsap     VHPWSRPSLQDCLAHPWL
Obscn_Hsap      RAPQARPSAAQCLSHPWF
Obscn~b_Hsap    AQPWGRPCASSCLQCPWL
Obscn_Mmus      RTPRARPSTSQCLAHPWF
Obscn~b_Mmus    AQPWGRPCASTCLQCGWL
SPEG_Mmus       QD-RLRPTAEETLEHPWF
SPEG~b_Mmus     VHPWSRPSLQDCLAHPWL
Trad_Mmus       EDFRRRPTAATCLQHPWL
Trio_Mmus       EDPAKRPSAALALQEQWL
Trad_Spur       ADSSERKTTSECLMNHWF
                     *      *   *: