Gprk1_Dmel MADLEAVLADVSYLMAMEKSKCTPAARASKKLNLPDPSVRSVMYKYLEKEGELNFHKNFN
BARK2_Mmus MADLEAVLADVSYLMAMEKSKTAPAARASKKVVLPEPSIRSVMQRYLAERNEITFDKIFN
BARK1_Mmus MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
BARK1_Hsap MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
BARK2_Hsap MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
W02B3.2_Cele MADLEAVLADVSYLMAMEKSRSQPAARASKRIVLPDPSVRSIMQKFLEKSGDMKFDKIFN
BARK_Spur MADLEAVLADVSYLMAMEKSKSTPAARASKKLVLPDPSVRTVMYKYLEERKEITFEKIFG
AqueK007_Aque MADLESVLADVSYLMTIEKSR-NPGAKTLKKIVLPDNSVHDVVHKWLSFKNELNFHRIHK
*****:*********::***: *.*:: *:: **: *:: :: ::* ::.*.: .
Gprk1_Dmel EVLGYLLFKDFCENDSEEPIQQLKFFEQIKLFEKTECYDERKKMARDIYDNFIMEEMLSH
BARK2_Mmus QKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRLRRSRQMYDAYIMRELLSS
BARK1_Mmus QKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLETEEERVVRSREIFDSYIMKELLAC
BARK1_Hsap QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
BARK2_Hsap QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
W02B3.2_Cele QKLGFLLLKDYAENVSESPCPQIKFYEAIKEYEKMETPDERLTKAREIYDHHIMVEMLAH
BARK_Spur QKLGYLLFKDYCENCADVQVQQLQFYEAIKDYEKLDTLDERLEEARRIFDNYIMKEVLSC
AqueK007_Aque QRMGTYFLEKFIP----PLCVTYSFLKAILDYEKTSSIVSRQKKAKQIYDKYIYADMLAM
: :* ::..: .* : * :** . .* :: ::* .* ::*:
Gprk1_Dmel TYEYSKHAVASVQKYLLKNEVPVDLFEPYLEEIFTQLKGKPFKKFLESDKFTRFCQWKNL
BARK2_Mmus THQFSKQAVEHVQSHLSKKQVTATLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
BARK1_Mmus SHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
BARK1_Hsap SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
BARK2_Hsap SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
W02B3.2_Cele AHNYSKESLQHVQYHLLKQNVPPDLFHRYVLEICDQLRGDIFQRFLESDKFTRFCQWKNL
BARK_Spur THQFSKSAVENVRQRLTNQEAKPDLFSDYITEILNSLKGEIFQKFLESDKFTRFCQWKNV
AqueK007_Aque SSKIPKEITDKVTVSLKANEVSTKLYGEIKEYLYDELTGLYMKDFIHSSHYVRYCQWKYI
: .* * * ::. *: : .* * :: *:.*.::.*:**** :
Gprk1_Dmel ELNIQ--LTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALN
BARK2_Mmus ELNIH--LSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALN
BARK1_Mmus ELNIH--LTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
BARK1_Hsap ELNIH--LTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
BARK2_Hsap ELNIH--LTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
W02B3.2_Cele ELNMQ--LTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
BARK_Spur ELNINGMLSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKSGETLALN
AqueK007_Aque ELSVPHTISLSDFNVHRIIGRGGFGEVFGCRKDDSGKMFAMKLLDKKRIKVKRGELLALN
**.: :::.:*.*************:**** *:***:*** *****:*:* ** ****
Gprk1_Dmel ERNMLQAVSTGIDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGIFSEDEMKFY
BARK2_Mmus ERIMLSLVSTG-DCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFY
BARK1_Mmus ERIMLSLVSTG-DCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFY
BARK1_Hsap ERIMLSLVSTG-DCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFY
BARK2_Hsap ERIMLSLVSTG-DCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFY
W02B3.2_Cele ERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFY
BARK_Spur ERIMLSLVSET-DCPFIVCMTYAFQTPDKLCFILDLMNGGDLHYHLSQHGVFSEEEVGFY
AqueK007_Aque ERNMLAKVN----SPFVVNLYYAFQTPEKLCFILDLMNGGDLHYHLTQHGVFNEAEVRFY
** ** *. .**:* : ***::*:**.**********:****:***:*.* :: **
Gprk1_Dmel AAEVILGLEHMHKRCIVYRDLKPANILLDENGHIRISDLGLACDFSKKKPHASVGTHGYM
BARK2_Mmus ASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYM
BARK1_Mmus AAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTHGYM
BARK1_Hsap AAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYM
BARK2_Hsap ATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYM
W02B3.2_Cele ASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYM
BARK_Spur AAEIILGLEHMHVRNVVYRDLKPANILLDENGHVRISDLGLACDFSSKKPHASVGTHGYM
AqueK007_Aque AAELILALEHIHSQLIVYRDLKPSNVLLDEAGHIRLSDLGLACEFSDRKPSSCVGTHGYM
*:*:**.***:* :*******:*:**** ** *:*******::*.::* :.*******
Gprk1_Dmel APEVLSKGTSYD------------------------------------SCADWFSFGCML
BARK2_Mmus APEVLQKGTCYD------------------------------------SSADWFSLGCML
BARK1_Mmus APEVLQKGVAYD------------------------------------SSADWFSLGCML
BARK1_Hsap APEVLQKGVAYD------------------------------------SSADWFSLGCML
BARK2_Hsap APEVLQKGTAYD------------------------------------SSADWFSLGCML
W02B3.2_Cele APEVLAKGVAYD------------------------------------SSADWFSLGCML
BARK_Spur APEVLSKGTAYDSSADWFSLGCMLFKLLHGGTHGYMAPEVLSKGTAYDSSADWFSLGCML
AqueK007_Aque APEVIQKGVHYD------------------------------------KSADWFSLGCVL
****: **. ** ..*****:**:*
Gprk1_Dmel YKLLKGHSPFRQHKTKDKLEIDKMTLTMNVELPE-SFSLELKNLLEMLLQRDVSKRLGCM
BARK2_Mmus FKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPD-AFSPELRSLLEGLLQRDVSQRLGCG
BARK1_Mmus FKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPD-SFSPELRSLLEGLLQRDVNRRLGCL
BARK1_Hsap FKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPD-SFSPELRSLLEGLLQRDVNRRLGCL
BARK2_Hsap FKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPD-TFSPELKSLLEGLLQRDVSKRLGCH
W02B3.2_Cele YKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCR
BARK_Spur FKLLHGHSPFRQHKTKDKHEIDRMTLTMDVEFPD-KMSDEMRALLAGLLQREVASRLGCE
AqueK007_Aque YKLLRGHSPFRS---QNKDEVDQITLTKEVTMPS-SFSPGVSQLLTGLLEKDPTKRLGCL
:***:******. ::* *:*::*** : :*. :* ** **::: ****
Gprk1_Dmel GNGADEVKMHNFFCGIDWHQVYIQKYTPPLVPPRGEVNAADAFDIGSFDEEDTKGIKLND
BARK2_Mmus GGGARELKEHIFFKGIDWQHVYLRKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLD
BARK1_Mmus GRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLD
BARK1_Hsap GRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLD
BARK2_Hsap GGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLD
W02B3.2_Cele GKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAADAFDIGNFDDDEVKGVKLQD
BARK_Spur GRGATEVREHPFFKTTDWNQVYYQKVQPPLIPPRGEVNAADAFDIGSFDEDDVKGIKVRN
AqueK007_Aque DTGVDAIKELPFFSDLNWDDVMEKKYAPPLIPPRGEVNAADAFDIGSFDSDETRGVKLND
. * :: ** :*. * :: ***:***************.**.::.:*:*: :
Gprk1_Dmel ADQDLYKMFSLTISERWQQEVSETVFDTVNTETDKLEQKRKLKQKQ--H-FDADE--KES
BARK2_Mmus CDQDLYKNFPLVISERWQQEVVETIYDAVNADTDKIEARRKAKNKQ--L-GQEEDYAMGK
BARK1_Mmus SDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQ--L-GHEEDYALGK
BARK1_Hsap SDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQ--L-GHEEDYALGK
BARK2_Hsap CDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQ--L-GHEEDYALGK
W02B3.2_Cele GDSDLYKNFNIVISERWQNEIAETIFEVVNQDADKAESKKRSKQKI--K-VAVEE--KDS
BARK_Spur L-----------------------------------------------------------
AqueK007_Aque EDQKMYSRFNVVVSDRWQAEMMESVFDSVNQDKEKQEGKERSKSKNGILPFYTADGSFTD
Gprk1_Dmel DCILHGYIKKLGG-SFASLWQTKYAKLYPNRLELHSESGNNKPELIFM---DQVEDISSD
BARK2_Mmus DCIMHGYMLKLGN-PFLTQWQRRYFYLFPNRLEWRGEG-ESRQSLLTM---EQIMSV--E
BARK1_Mmus DCIVHGYMSKMGN-PFLTQWQRRYFYLFPNRLEWRGEG-EAPQSLLTM---EEIQSV--E
BARK1_Hsap DCIMHGYMSKMGN-PFLTQWQRRYFYLFPNRLEWRGEG-EAPQSLLTM---EEIQSV--E
BARK2_Hsap DCIMHGYMLKLGN-PFLTQWQRRYFYLFPNRLEWRGEG-ESRQNLLTM---EQILSV--E
W02B3.2_Cele DVIVHGYIKKLGG-PFTSAWQTKYGKLYPSRLELYPESLTAKPELVFM---DQIEDVCAE
BARK_Spur --------------PFLTFL----------------------------------------
AqueK007_Aque DSLLQGYGSKQSTAAMFTHWQRKYFKLYPNRLDIGDSFTSMSKGLVSISFTESSILV--E
.: :
Gprk1_Dmel FILHKNENCIQIRINDGTRDGRIILTNS-----------------------DEIGLKEWS
BARK2_Mmus ETQIKDRKCILLRIKGGKQ---FVLQCE-----------------------SDPEFAQWL
BARK1_Mmus ETQIKERKCLLLKIRGGKQ---FVLQCD-----------------------SDPELVQWK
BARK1_Hsap ETQIKERKCLLLKIRGGKQ---FILQCD-----------------------SDPELVQWK
BARK2_Hsap ETQIKDKKCILFRIKGGKQ---FVLQCE-----------------------SDPEFVQWK
W02B3.2_Cele MQTIKGETAIIVKLRDGFK---EPKICLTNSVSENVLKYKTEKKNCRSVYLDEISLKEWH
BARK_Spur ------------------------------------------------------------
AqueK007_Aque SKQIKGTDIIRLQPIGTRR--ETCIKFE-----------------------SQLEHQMWF
Gprk1_Dmel SSLRSAHKISQDLLGSMAKKAGKIY----GSERDVNKSM-YIFG------------GNCS
BARK2_Mmus KELTCTFNEAQRLLRRAPKFLNKPR----AAILEFSKPP------------------LCH
BARK1_Mmus KELRDAYREAQQLVQRVPKMKNKPR----SPVVELSKVP------------------LIQ
BARK1_Hsap KELRDAYREAQQLVQRVPKMKNKPR----SPVVELSKVP------------------LVQ
BARK2_Hsap KELNETFKEAQRLLRRAPKFLNKPR----SGTVELPKPS------------------LCH
W02B3.2_Cele TSLRTAHKVSQELLQRMGRKAIKIYGVNHDPMLSESERPGSVTR------------AFLN
BARK_Spur ------------------------------------------------------------
AqueK007_Aque RFLRDAIHKHDST---------KDP----SGPIALEDGG-LIQRRQISDSPARRARELGY
Gprk1_Dmel TKTS-NGSN
BARK2_Mmus R-NS--SGL
BARK1_Mmus R-GS-ANGL
BARK1_Hsap R-GS-ANGL
BARK2_Hsap R-NS--NGL
W02B3.2_Cele RASSVDSGV
BARK_Spur -----NLKT
AqueK007_Aque TR-S-VPIL