Protein (view, download) , Domain (view, download)
Erk1_Ddis       MEPEFDHFQSQM-------------------DSD-------------------------N
13785_Tthe      MQNLSNFDSL--------------------------------------------------
18504_Tthe      MEHQVP--KE--------------------------------------------------
18512_Tthe      MDTANLVAKE--------------------------------------------------
18725_Tthe      MQQQQNQ-----------------------------------------------------
23186_Tthe      MHPNQEQEKYGM-------------------QANRMNPTAGNMVDQSKQDIMYQNNFNGG
4173_Tthe       MNLQAQQKTRKQSKGQILEIFEQIKPTHYIQDT---------------------ANGVST
6784_Tthe       MKGQSMYQNS---------------------------------------------NNTSG
28107_Tthe      MDIKRNMETT--------------------------------------------------
23757_Tthe      SK----------------------------------------------------------
17883_Tthe      MQNLPNFDEQ--------------------------------------------------
13784_Tthe      MYY---------------------------------------------------------


Erk1_Ddis       THQSTMFNVQDNNAILMSGMENVLQSPR--------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      NNPNE-MNY---------------------------------------------------
4173_Tthe       KSFTK-QIRYQSQN------------PKMSNQKEKRNQEYLFHIGNHARTVSDILKFRYD
6784_Tthe       NNFSY-MNYNQNQSI-----------PS--------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       --QLQAAAQ-AQQQAAAQAQQQQVQAQQVQAQQAQQQQQQQQN-----------------
13785_Tthe      -------------------------------SQSQLQAFSQQN-----------------
18504_Tthe      ------------------------------------------I-----------------
18512_Tthe      ------------------------------------------V-----------------
18725_Tthe      ------------------------------QQQAQQQQLQQQQQQQ--------------
23186_Tthe      ----------YR---------------N---NQLQQQNFIENNNNMYAANNINMVMPPQG
4173_Tthe       QYK-----QTLG---------------QQEQQSEEQQRMQYQNQQS--------------
6784_Tthe       --S-----Y-YQ---------------QQQNQQSSQQPLQQQNQNIT-------------
28107_Tthe      ------------------------------------------K-----------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      -------------------------------SHSQQE-VLRQN-----------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      QYI---QDPNAQVIHQQQQYDDQNYYPMNGVNTQQNQQ----------------------
4173_Tthe       --IWQNSTTMIQQYQQYHQAQESNIKRSNTLSNLQSQKSGVKICNSASKQSEKNQNTQKL
6784_Tthe       ------SYSRSQSRHSHHQSENVNISATNNTNNMQSQN----------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       LYKPAQIQSQKAISSILGSAESNISPIKKSYNEDLATAGDTRDNFASLSGGSLKSNPNNF
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ----HQFVN---------------------------------------------------
4173_Tthe       SFQDRKYVSEKDYLSIQRNLFDSIDTQKNSSIQNQQCSSIVQSKKESDEIDFNKQSKLEK
6784_Tthe       ----QKYVK---------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       QNNQTFNKEDRLLQSPASLHLNQKSQSQDYLAQKNPTQQQQMSPHLIQPSHLLFVDSQQN
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       -------------QQ-----------------------------Q---------------
13785_Tthe      -------------PL-----------------------------R---------------
18504_Tthe      -------------IE-----------------------------Y---------------
18512_Tthe      -------------VE-----------------------------Y---------------
18725_Tthe      -------------QQ-----------------------------H---------------
23186_Tthe      --------MQGD-MQNQQILKQGNDFQQIQYMMGGGEGVQIDHQYT--------------
4173_Tthe       QNQINYPNQFIS-----------------------------SISQTSGQQNQTQEQFKID
6784_Tthe       --------QSTSSMSHTQS-------------------------N---------------
28107_Tthe      -------------ID-----------------------------Y---------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      -------------SS-----------------------------R---------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       QFKNNQINNNQKFLNQINYSQYNSIPSLDISQAQNKEGIINTDIKPIQKYQENLQSTSTI
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       --------------------------------Q-----QQQ-------------------
13785_Tthe      --------------------------------F-----LSF-------------------
18504_Tthe      --------------------------------Y-----KPY-------------------
18512_Tthe      --------------------------------Y-----QPY-------------------
18725_Tthe      --------------------------------Q-----QAQ-------------------
23186_Tthe      ------------------------------MYNQL---QNH-------------------
4173_Tthe       ETNQLAQANKITESKFTNFAKSNDQSQMQSASDIYSFNQPYSTSQISSQILSTERQFKIK
6784_Tthe       --------------------------------QVY---QNS-------------------
28107_Tthe      --------------------------------S-----K-Y-------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      --------------------------------Y-----LSF-------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       --------QNQQ------------------------------------------------
13785_Tthe      --------QYTE------------------------------------------------
18504_Tthe      --------ENKK------------------------------------------------
18512_Tthe      --------RHK-------------------------------------------------
18725_Tthe      --------QHQE------------------------------------------------
23186_Tthe      --------QFDQNY-------------------------------G-MN-----------
4173_Tthe       LTKITKDSQISEEYQINKSPSSFTQLENKQDLLIKFAEARKQEHLNNLYDDAQSDFSKTP
6784_Tthe       --------QLRENY-------------------------------NNLS-----------
28107_Tthe      --------INE-------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      --------QYTE------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ----------------------------------------ND------------------
4173_Tthe       QTNKSEVIKRFKASQIFDQNQSQANSKPSQNKSSQIYYNNNSQYDFANSVKEINNEHKYT
6784_Tthe       ----------------------------------------NN------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       NLMSSAQQQNLSHQIPTLSGMGRINNFIRKSQEGNKQSNYFTQISDSQIQNAGNVTKQSA
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       SFNPNYHLLESYTNSLVKQNNNETLNPLNTQNQIKNLIDYNSPKQNIQNIQASGLYNQSS
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      --------------LKPATVNSQYPQIGNPNYQ--------------S------------
4173_Tthe       FQQETKSSLSMIKNI---------------FESTLNNQENPSNQNLISSSPKNLELNIIL
6784_Tthe       --------------SNAKSSQIQSSQTGNIRPSTVANILNNNSTNKIS------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ----------------NQQQQQNQQQQ---------------------------------
13785_Tthe      ----------------ND------------------------------------------
18504_Tthe      ----------------SN------------------------------------------
18512_Tthe      ----------------SN------------------------------------------
18725_Tthe      ----------------KP--QKPI------------------------------------
23186_Tthe      ---------AQFYQKQQH--LNTLQEQ---------------------------------
4173_Tthe       SKYQSNKEKQ------------------------------------NLRQSSQFQQQTPS
6784_Tthe       ---------Q------NT--IQNL--KQTNQVIPNNSKVNNENRVQN-------------
28107_Tthe      ----------------KP------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ----------------NN------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       IQLETKNSFAKSIDQHFSQQNTRLSNTLAELNQSSQVKNSLTVLENQKIQQIMDDIQAKI
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       SLKKSQSLEQSGIAMQSSSNKFSQYFEKKTSNSQVIDNGMNEQNGLIVSFANNSLVGQST
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       IESSKNIANQMNYYINSASQIVIDEAYNKQKIEKNPVSAQFILQDNQTATSQTDSKKDIE
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       NPTSQNNYNLTLEGEQNQSDNPPSERKKMHADFSSDKSQKGEQDKTFDSENRDEMSIKQT
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       TQFEKKAETLSNTYDMSQLLCQTPLQQHGQHIRLMSGGNMEHLTLNNSIQSTFPFEQIQS
6784_Tthe       ----------------------------------------------N---------TITS
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ----------------------SQQMTQQQL-----------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ----------------------NQKQNNQEV-----------------------------
4173_Tthe       NQTTSYNNYSNFTTSNNLQSANNHQSKNQEVGLNLQNSFDNGEQNIQIQVKSSQITRQSQ
6784_Tthe       NQNTLTNNTNNVISSSINANNNNQQSNNQQI-----------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       EKREQQNPELELEKKSSKEIGRSQDSNLNTPQKCSENLQQLLNDNQQSKYNTPQTIVSAQ
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       PNELENQNIYEDQEVQYVQTATHNQERELQEYDKQNFTNPELLNQSKQLQESQNRDLQVQ
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       AAHHNKEKELQEYNNQNIANIEQLNKSKQLQESQKGDQNQQENSMLQGQIGENENEKQKN
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       IQKNINHVRFNNLVKQMQENSPCHNLGYYHYETINIDGKILKDVYQQTDNIEKKEISVQT
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       IEQSKRNSIFDECTKLFSPKMKFIEPEFKDNECMMLNMSNNSSQYDHKDSIKEQHEGGFN
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       YDQNQQKNLRKSDFFKQQPNQQQQQQTSSNGNHETGIINSSLYNSQKLASDNEEVIKRQY
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       QIYDKIFDAGELPVVDCTEQDNIFKEWYQSDQSNFKNRRYSNQISDSEKKNIQQQIDNIV
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ----------QQLM-------------P--------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ---------------------------Q--------------------------------
23186_Tthe      ----------K--L-------------K--------------------------------
4173_Tthe       NKRAYKNQQAL-MNQ----QKNSQSNQPQIGKNKSKQQTKVPNKQNQKSIKFNNKIETRN
6784_Tthe       ----------S-SISASLKASTTNTKNQ--------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       IPKNSKQKNSAIPGNNTERVFERLYPKQVKQQQEQIFEIKKDTSKSKSKGRATSQFKTQE
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       EMDFIKINKQKVPYMMRKKVEDKFQLFKKAVEVNLENMIQDQKSHQIKSIVLDDEIKDQD
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       NLQEIYQRSLSNRTQKNLVSYDSQTMTNLARMDIQKDTSRVYKNNLSSYKQNPESGAKFL
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       IKRNLKELVQKVLKDANEFTHTNYIKLKALCSLQNIIVLAEHHIQEYLKDIMKVLVKFLD
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       YDDPEIPNTCKRISELLGIYVSSEVYIPLAISLIHDEEHKTAPKSLTKLLTIFSIMIRGE
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       TPKTIEGYLDTIMKTVTSVEKTFDNKIFMQIRESEEVLSGLYYIAKELINISGENISIYC
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       RPIFSLLLTVQATNTAGKDNQNEIQKTMLTLATYCGYSSIAELHANEVSMLLNEFTTNKS
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       YKTWQKYSKDRLKFEIIVRNCGEGLSKFIDIILEILQSCVELNQDIEVRMDALVLVEFII
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       CLQFKDVQEKLKENAQLILTKILIPSIVWKIGKPQIKIRKAGIINIYKLIENGLVTGDVL
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       -------PPPTSDT----------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      -------VPP--------------------------------------------------
23186_Tthe      -------QQPNSDT----------------------------------------------
4173_Tthe       MKCFKELMPPIKSCLSDDWAPDLRLAACKLAEKLFLEVRDHLEHIHISENYQLLLERLDD
6784_Tthe       -------IQK--------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       SQDVIRVEIFKTFTVIFGAPALKESPSIFEYMVKAIFIHLDDQNEDVQMGAYNTLKFAAR
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ---------------------------------SNFNDNISY-FVYGSQFTVPRRYSIV-
13785_Tthe      --------------------------------------LHSF-NYYTSVYKIEKRYRIL-
18504_Tthe      --------------------------------------IRVQNVLSASKFEMDDNYSII-
18512_Tthe      --------------------------------------FTVT-QVHGSVFNIDERYRIL-
18725_Tthe      -------------------------------------GKHKF-DCGQTIFVVDEKYEYI-
23186_Tthe      ---------------------------------EDP-YFNSI-FIFQNRFDVPKKYQLL-
4173_Tthe       INPAKIKEEPQQQLAAQNQLKPKQGHFYQKGKPFVKKGRQLS-DISGTYLVVYDHYQIV-
6784_Tthe       -------------------------------------KRKTF-ECGGTAFSVDDHYEFH-
28107_Tthe      --------------------------------------FTKW-KLNDIEFYMESSIQNLQ
23757_Tthe      ----------------------------------------SY-QQNGITFTTGERYEVD-
17883_Tthe      --------------------------------------LYSF-KDREKVYKIEKRYQIL-
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       KCIGHGAYGVVC-SAKDNL------TGEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKH
13785_Tthe      KQIGFGF-NPTF-TAIDQEY------GQKVIIEVIKIENDDLIYMNQLIRQIKIENHFKH
18504_Tthe      DSIGQGAYGIVV-AARDLNCQ--DEENNLVAIKKIEKAFEHKIFTKRTLRELRLLRLLKH
18512_Tthe      EKIGQGAYGVVS-AAIDQV------KRKSVAIKKIEKAFDQRIYTKRTLRELKLLRLLTH
18725_Tthe      KQIGYGAYGVVC-SAVNKEN------GSKVAIKKVQNAYDDLIDAKRIVREIKLLKFFEH
23186_Tthe      VPIGIGGYGVVA-KAFDQEK------QDFVAIKKIFKPFLNPLETKRILREIKILKALEH
4173_Tthe       KRIGDGAYGVVF-KAIDKSK-----NNEIVAIKKVSDAFLDPRDAKRILREIKLLKFCNH
6784_Tthe       KQIGHGAYGVVC-SGVDTKC------NKKIAIKKITNAFEDLVDAKRIVREIKMLKFFDH
28107_Tthe      IKAGQGTFGVVV-ACQDKEKEFFDEDSDFVAIKKIERAFEHTQYAIRTIREIKLQRMLAH
23757_Tthe      KLLGSGAYGQVV-RAKDKKN-----QNQYVAIKKLHK-IEDVIDAKRVLREIRILRYLVH
17883_Tthe      RLIWRDTNISFCLAAIDREY------GQKVFIKVIKLEECILKYIIQAIRSIKIENHFQH
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ENLISIKDILKPNS--KEQFEDVYIVSELMDTDLHQIITSPQPLSDDHCQYFVYQMLRGL
13785_Tthe      ENISSNLHIMM-------ESKNLYIVREFIDTDLHRVNFSKQELTDDHIQYFTYQILSAL
18504_Tthe      ENIIGINTLLLPRS--REKFEDIYVVSELMETDLASIIKSEQPLTDEHCQFFLYQILRGL
18512_Tthe      ENVIGLESILLPKS--REEFDDIYCVSELMETDLQQIIKSDQQLTQDHCKFFIYQILRGL
18725_Tthe      DNIISLLDVIKPNA--PVGDEDIYMVFDLMETDLHRVIYSRQELSDEHIQYFVYQILRGL
23186_Tthe      DNIISIRDVLSPVP--KEKLEDIYIISQLMDTDLHQIIASDQILSEDHIQFFIYQLLCGL
4173_Tthe       PNIIKLKDIIKPEM--PTGYKDIYLVLEYMEIDLDKTINSEQALSPKIIKNLMWQLLNGI
6784_Tthe       ENIIALHDIIVPEQ--RTDYNDIYIVTELMETDLHRVIYSRQELTDDHIQYFLYQTLRGM
28107_Tthe      ENLL------LPKS--REQMNDIYLVEPLMTSDLRAIINSQNEINEEHIQFLMYQIIRGL
23757_Tthe      ENILQLSDILYDDEDENQEFGTIYLVTNYMEIDLYQVIKSDQKLSDQHIQYIIYQILKGL
17883_Tthe      ENINSNLHIMM-------ESKNLYIVKELMDINLKDVTFSRQELTDEHIKWFVYQILKAL
13784_Tthe      ----------------------------------------------------LLN-IKSS
                                                                      : : .

Erk1_Ddis       ----------KHIHSANVLHRDLKPSNLLINEDCLLKICDLGLARVEDAT----------
13785_Tthe      ----------FFLHSQNVYHTQLRLSNILLNKNCDLKISRFIGTNF----PN--------
18504_Tthe      ----------KYIHSAKVVHRDLKPRNLLVNSNCDLKICDFGLARTIIPGLKC-------
18512_Tthe      ----------KYIHSANVIHRDLKPRNLLVNSNCDLKICDFGLARSVAN-----------
18725_Tthe      ----------LYIHSANVIHRDLKPSNILLNKNCDLKICDFGLARGFEEP-G--------
23186_Tthe      KYVNQIYYFLKYIHSAGVFHRDLKPGNLLVNSDCVLKICDFGLARTVDTKVNV-------
4173_Tthe       ----------FYMHSADIIHRDIKPSNILLNKNCTLKLADMNLARKFDVEQSSIT-----
6784_Tthe       ----------LYIHSANVMHRDLKPSNILVNKNCDLKVCDLGLARGFEFDEE--------
28107_Tthe      ----------KYMHSAQIVHRDLKPKNVLSNEQGDLKICDFGFARHIQKN----------
23757_Tthe      ----------KYLHSANIIHRDLKPSNLLATEKCAIRMCDFGLSRSIEDEQKQEQQLVRN
17883_Tthe      ----------NFLHSQNVYHTELTARDILLKENCDLKITGFIHSNF----PH--------
13784_Tthe      ----------FFLHSQNVYLYVMKRDSILLNQNCELKISDFLGAKF----PN--------
                           .:**  :    :   .:* ...  :::  :  :.

Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ------------------------------------------------------------
4173_Tthe       ------------------------------------------------------------
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      LILFFSFIILMHNLHKQTNKQINKKTNKPNQYLFQTLLSYSLKQFIHNCNQFSLYEFYTV
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ----------HQGFMTEYVATRWYRAPEVILSWNKYTKAIDIWSVGCIFAELLGRKPLFQ
13785_Tthe      ------------EIYSQYITSDYFLSPQQILNLPKNLSKTDIWHVGVIILGLINRDTFFS
18504_Tthe      ----------RAGMLTDYVATRWYRAPELLLSWRDYDEKVDVWSVGCIFAELLRRKPFLP
18512_Tthe      ----------TKNDLTDYVTTRWYRPPELLLSWTDYTCAMDVWSVGIIFAELIKRKPLLP
18725_Tthe      ------------ESLTEYVITRWYRAPEVILNASEYNQAVDIWSVGCITAELLGRTPLFP
23186_Tthe      -----------LVLMTEYVATRWYRAPELLLSWNKYTTAIDMWAVGCIFSELYMRKPLLP
4173_Tthe       -----EQQISLNLYFTTYVVTRPYRAPEILLSTENYSKPIDIWSAGCIFAEMMGRKTIFK
6784_Tthe       ------------DGKTEYVVTRWYRAPEVILKASKYTKSIDVWSIGCIFAELLGRTPLFP
28107_Tthe      ----------RVNDLSEYVTARWYRAPEILLSYKKYDIAVDMWSCGIIMAELLKRQPIIR
23757_Tthe      NKKQASKQI-NTCQLTEYVVTRYYRAPEIMLSSHVYSKAVDIWSLGCTFAELISHQILFK
17883_Tthe      ------------E--VNYYNKKGYYPPQRILELPENLSKTDIWHVGVIILQLLYGYPFFE
13784_Tthe      ------------DFDKKYINTNSYLSPYYILGLPEDFSKTDIWNVGVIILELFQIKNIFS
                                 *     : .*  :*         *:*  *     :     ::

Erk1_Ddis       GKD------YIHQITLIIETIGSPSEEDICNIANEQA---RQFIRNMGNQPKVNFANMFP
13785_Tthe      NLSNQLGGGYLGLINAIFSYIGTPSGEELLQYQ--DYKGLYQY---IIKYSKKSWQDVFP
18504_Tthe      GID------TRNQIELIFEYLGTPSEQEINNIPREKF---RKMVKNMPKRQPKQFEKLFS
18512_Tthe      GSS------SSDQLLRIFDLIGTPLENEIQMIPYDEY---RKFIRELPKREPKQFEKIFS
18725_Tthe      GEN------YLDQVQRVIAVLGTPTQEDMAYIGNQDA---IKYIKSQPKRTKQSWQSLYP
23186_Tthe      GES------YLNQLILTLNLTGTPSKEDLENIQSDRA---KQFIISLGNKAPKDLSKLIP
4173_Tthe       GNS------YVNQLDRIIAIMGKPDFDKLSYKVDENL---KEYIKQLQEKQPENFYEIYK
6784_Tthe       GKD------YLEQIQRIIAILGTPTPEELSYITNEGA---LKYLKSLPKRTKQSWENLYP
28107_Tthe      GAS------TDDQMRQILQLIGSPDEYQVK---DPEY---KKLLSYFPYCPGKNFKLIFP
23757_Tthe      ADN------YIKQIKLIFDKLGMPPEEDLQFIGNSNA---KQFVNTLAKKNSVKVSSFIN
17883_Tthe      KRNR---GGRNGVLQAYFYSIGSPSEEDLSQYK--DYTEQYEQLKSLNQYCKKSWQDQFP
13784_Tthe      DFCC---SASGGLLTNYFYYIGSPSKEDLDLLLEKGYKQQYNELLSLPFYRKQPWQVVFR
                             :   :   * *   .:            :

Erk1_Ddis       KANPDAIDLLERMLYFDPSKRLTVEEALAHPYFQSLHDPSDEPICLH--KFSLNFEA---
13785_Tthe      DANPLLCDLLDKMLVFNEDKRYTVKECLQHPYFEDLYDLDDIDECDV--KFDHSQFQI--
18504_Tthe      KASKEAIDLLRKLLTFDFTKRITVDEALSHPYLSELHFPEDEPTCEPVSKLDFEFEE---
18512_Tthe      KAPKEALDLLKKMLTFDFNKRITVEEALKHPYLSDLHLPEDEPSRSEVPFYEFEFEM---
18725_Tthe      KANPLALDLLSKMLTFNPEKRYTVKECIEHPYFEGLHYPDEEPECEQ--VFDWSWDK---
23186_Tthe      NASPQAIDLISKMIVFNPDKRISAEEALKHPFFEGIRESEFEVEAKV--KFDFDFER---
4173_Tthe       SHDPLAIDLLYKMLAFDPKERWTVEQCLYHEYFKDFDKS-QIKACNH--KFDWTFDE---
6784_Tthe       NANLVGLDLLSKMLTFNPNDRYTIEECLAHPYFEGLHNPEDEPTCPE--VFDWAWDD---
28107_Tthe      NASSQCLDLLKKLLQIDPSQRITAEQALAHPFFEMLHDPSDEPDCEPINQAEFEYEN---
23757_Tthe      YENPLALDLIDKMLAINPSKRITADEALEHPYFQSIRDVQEEIKFTG--TINFDFET---
17883_Tthe      NANPLLCDLLDKMLVFNEDKRFSLKECFLHPYFEDLYIPDDFQQCNL--KFDHSQLQIGS
13784_Tthe      RENPLLYDLLDKMLVFNEDKRYTVKECLQHPYFEDIYYQEDIYECDI--QFDHSQFQI--
                       **: ::: ::  .* : .:.: * ::. :               .

Erk1_Ddis       ---WDLNRDLLKELIYNEMLAY-HPED---------------------------------
13785_Tthe      ----GLNEDEIMKEIYFEVEKSYQKQQ---------------------------------
18504_Tthe      ---HNLTLQQLKDLIYEEILYY-HYPS---------------------------------
18512_Tthe      --HSNLTRQQYKDLVYEEILLY-HYPD---------------------------------
18725_Tthe      ---FTPTKEILQKMIYQEAKSF-HP-----------------------------------
23186_Tthe      ---EDITLDELKDAIYQEMLKF-HPTFDENNKETYHIPIKRDSDLFTLDYDGSKIYIDYK
4173_Tthe       ---IQERNDLIQRAIYNESCQF-HQDEPDATIEE--------------------------
6784_Tthe       ---FELTKERLQGMVYDEAIDY-QKV----------------------------------
28107_Tthe      ---YDLNDQQLKDILYEEILLY-NSPE---------------------------------
23757_Tthe      --DSEITIESLRKQILEEVNHF-RQV----------------------------------
17883_Tthe      NEDEDIDKEEVMKDIYFEVEKSYQKQQ---------------------------------
13784_Tthe      ----GLSKNEVMKEIYFEVEKSCLKQQ---------------------------------
                        :     :  *

Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      LGQNDQPQQVVQNIQQINEKMVKDIIGVDGNGKMIQDQQFIQMPYYNNTIFSPSQVEQQN
4173_Tthe       -------------------------------------------------------V-E--
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ---PQ--APYYTDL------N------N-----------------------PNFN-----
13785_Tthe      ---KQKLKRYQIQI------I------Q-----------------------NIAF-----
18504_Tthe      ---FK--QEYETKK------A------N-----------------------GQSL-----
18512_Tthe      ---FK--KKYLDKI------Q------N-----------------------NQSV-----
18725_Tthe      ------------------------------------------------------------
23186_Tthe      YQHYQ--QQQQQLYQQNYNVQQQQHQTDTQNIE-------YQQQQQQPHLQHQAVFNHEG
4173_Tthe       -QHYK--Q-QQQIIQQK--I-AQQHAANANSQQFLKTNQQFQM-NLEKLAASQPLINPIN
6784_Tthe       ----K--ATQQQQY----------------------------------------------
28107_Tthe      ---FR--EQYYEKL------K------K-----------------------GQSV-----
23757_Tthe      ----N--KVPPLKI------P------DLLALC---------------------------
17883_Tthe      ------LRRYQIQI------I------Q-----------------------NIAF-----
13784_Tthe      ------LKRYQIQI------I------Q-----------------------NIAF-----


Erk1_Ddis       ------------------------------------------------------------
13785_Tthe      ------------------------------------------------------------
18504_Tthe      ------------------------------------------------------------
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      GN-----------------------------QYMDIQQQQQQQQQ---------------
4173_Tthe       FNPNMQVPFFPMGRQPQVPPEAILLQMQNMQKNPML-QKQFQMMQGQQQTQMPLQKDFRN
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------------------------------------------------------
23757_Tthe      -------------------------------------EKRT-K-----------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       ------------LSRIQSSSELF-------------------------------------
13785_Tthe      ------------QKHLADQIPLNP------------------------------------
18504_Tthe      ------------ISHIINNANRNV------------------------------------
18512_Tthe      ------------MQHIFDNANKNI------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ----------------QQQYMMNQHYVD--------------------------------
4173_Tthe       PFNSHPLANLSQDKMKADSLPINPIQASAVQQNPLFVPGLHNFPPGFHPIKIGMQEQFKK
6784_Tthe       ------------------------------------------------------------
28107_Tthe      ------------YSHIIGDVEDND------------------------------------
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------QKHLAHQIPLNP------------------------------------
13784_Tthe      ------------QKHLADQIPLNP------------------------------------


Erk1_Ddis       --------------------------------------------------------NLLQ
13785_Tthe      ------------------------------------------------------------
18504_Tthe      --------------------------------------------------------PD--
18512_Tthe      ------------------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      ----Y------------------------------------------------NNNNQVF
4173_Tthe       PNINNNTNGNTNQQKPNQNDQSPPKTDSESKASDTNKNNHNGQNNGDENGKQEKNDKKFN
6784_Tthe       ------------------------------------------------------------
28107_Tthe      --------------------------------------------------------NDYD
23757_Tthe      ------------------------------------------------------------
17883_Tthe      ------------------------------------------------------------
13784_Tthe      ------------------------------------------------------------


Erk1_Ddis       -QQKQQ-IH---------------------------------------------------
13785_Tthe      --------K---------------------------------------------------
18504_Tthe      --PH--SSD---------------------------------------------------
18512_Tthe      --------V---------------------------------------------------
18725_Tthe      ------------------------------------------------------------
23186_Tthe      -INQQQ-EI---------------------------------------------------
4173_Tthe       KDNDQD-QEKQNNNNGEKDRKNSNNGLNQMSNQTTEEKENPESKSKMQNKESEMNRSQDF
6784_Tthe       ------------------------------------------------------------
28107_Tthe      -DDDEEDEE---------------------------------------------------
23757_Tthe      --------A---------------------------------------------------
17883_Tthe      --------K---------------------------------------------------
13784_Tthe      --------K---------------------------------------------------


Erk1_Ddis       -------------------------------QQVNQQSIKN
13785_Tthe      -------------------------------LIFYNLYEDL
18504_Tthe      -------------------------------DDQSDDDDEN
18512_Tthe      -------------------------------DEEFSSDQDY
18725_Tthe      ---------------------------------------IH
23186_Tthe      -------------------------------DQNDTQMREE
4173_Tthe       LKGSILSNSEEIEELPNIPEMRYKTLTFGPEQFNNNQKSAE
6784_Tthe       -------------------------------QQQQSYENQC
28107_Tthe      -------------------------------EDDDETKKTN
23757_Tthe      -------------------------------IQEKANLHKK
17883_Tthe      -------------------------------LIFYNLYEDL
13784_Tthe      -------------------------------SIFYNLYEDL