Protein (view, download) , Domain (view, download)
IRAK-0_i-1_Smoe   FSDDNKLGRGAFGTVFK----------------------------GV-LKDGSEVAVKQL
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    FSKRNKLGQGGFGTVYK----------------------------AT-LNNGSQVAVKKL
IRAK-0_t-2_Smoe   GKFSNCLGNGGFGNVFK----------------------------GL-LADGTEVAVKKL
IRAK-0_as_Smoe    FSEENQLGQGGFGVVYK----------------------------AN-LKDGTQVAVKKL
IRAK-0_aq-2_Smoe  FCEDSKIGEGGYGVVFK----------------------------GF-LPDGSVVAVKNL
IRAK-0_af-2_Smoe  FNPTKKLGQGGFGSVYV----------------------------GN-LQDQTLVAVKQL
IRAK-0_af-1_Smoe  FNPTKKLGQGGFGSVYV----------------------------GN-LQDQTLVAVKQL
IRAK-0_e-2_Smoe   FSDRNKLGQGGFGTVYK----------------------------AAFFGDGTVFAVKRL
IRAK-0_bn_Smoe    FSKECEVGCGGFGRVYR----------------------------GN-LEDGRTVAIKQA
IRAK-0_be_Smoe    FSSSNLISRGRRACVYR----------------------------AK-LPDEQQVVVKKT
IRAK-0_bm_Smoe    FDETNILGQGASGVVYR----------------------------GR-SSGGYNVAVKQL
IRAK-0_ar-1_Smoe  FSVESKLGQGGFGTVYK----------------------------AT-LNNGSQVAVKKL
IRAK-0_bh_Smoe    QNFSKELGRGGFAKVYY----------------------------GV-LPDGREIAAKVY
IRAK-0_x_Smoe     YSDEMVLGKGAFGAVYK----------------------------GV-LENGQAVAIKRA
IRAK-0_n-1_Smoe   FHRTTLIGQGGYGNVYK----------------------------GV-LKDGTVVALKRF
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   FSDDNKLGQGGFGVVYK----------------------------GT-LPDGRRIAIKRL
IRAK-0_au-1_Smoe  QGFSDKLGEGGFGAVYK----------------------------GT-LPSGTVIAVKQL
IRAK-0_au-2_Smoe  QGFSDKLGEGGFGAVYK----------------------------GT-LPSGTVIAVKQL
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  FDKEHKIGSGGFGTVYK----------------------------GL-FDDGSVLAIKRA
IRAK-0_ab_Smoe    FRSDLKLGTGSFGTVYK----------------------------GK-LDDGTTVAIKKA
IRAK-0_n-2_Smoe   FHRTTLIGQGGYGNVYK----------------------------GV-LQDGTVVALKRF
IRAK-0_a-1_Smoe   FS--KRIGSGGFGTVFE----------------------------GS-LSDGSRIAVKRL
IRAK-0_ae-1_Smoe  FDKEHKIGSGGFGTVYK----------------------------GL-FDDGSVLAIKRA
IRAK-0_ad_Smoe    FSIENKLGQGGFGPVHK----------------------------GV-LRNGQVVAVKSL
IRAK-0_ba_Smoe    FSPDNVLGEGGYGIVYR----------------------------GC-LGDGTPVAVKSL
IRAK-0_b-1_Smoe   FKAELMLGTGSFGTVFQ----------------------------GV-LDDDTPVAIKKA
IRAK-0_c-2_Smoe   FADCNVLGEGGYGIVYK----------------------------GK-LPDGTPIAVKNL
IRAK-0_aa-1_Smoe  FAESRLLGGGGFSTVYQ----------------------------GK-LPDGRIVAVKKL
IRAK-0_bb_Smoe    FDPARLLGKGAFGKVYK----------------------------GV-LSDGTLVAIKQL
IRAK-0_bg_Smoe    FAPGNVIGEGGYGVVYR----------------------------GR-LPDDTLVAVKNL
IRAK-0_t-1_Smoe   GKFSNCLGNGGFGSVFK----------------------------GL-LADGTEVAVKKL
IRAK-0_b-2_Smoe   FKAELMLGTGSFGTVFQ----------------------------GV-LDDDTPVAIKKA
IRAK-0_aa-2_Smoe  FAESRLLGGGGFSTVYQ----------------------------GK-LPDGRIVAVKKL
IRAK-0_aq-1_Smoe  FCEDSKIGEGGYGVVFK----------------------------GF-LPDGSVVAVKNL
IRAK-0_i-2_Smoe   --------------------------------------------------DGSEVAVKQL
IRAK-0_bj_Smoe    FAPEKKIDEGKFGELYKASVVCIFFFSNLSVANRSSCSLGFFYLQGE-LSDGTKFAVKKL
IRAK-0_c-1_Smoe   FADCNVLGEGGYGIVYK----------------------------GK-LPDGTPIAVKNL
IRAK-0_ac_Smoe    FSSENKLGQGGFGAVYK----------------------------GV-LPNGTVVAIKEL
IRAK-0_z-2_Smoe   FSETNQLGQGGFGTVYK----------------------------AC-LKDGTQVAVKKL
IRAK-0_k_Smoe     YSEEMILGRGAFGTVYK----------------------------GV-LQNGHQVAVKRA
IRAK-0_y-1_Smoe   FSSDMVIGKGAFGMVYK----------------------------AR-LPSGEILAIKKG
IRAK-0_z-1_Smoe   FSETNKLGQGGFGTVYK----------------------------AC-LKDGTQVAVKKL
IRAK-0_bq_Smoe    FSDDHKLGEGGFGAVYK----------------------------GT-FSDGTEIAIKKL
IRAK-0_aj_Smoe    FSDDKKLGEGGFGAVYK----------------------------GT-FGDGTEIAIKKL
IRAK-0_br_Smoe    FSDINKLGRGAFGTVFK----------------------------GV-LKDGSEVAVKQL
IRAK-0_l_Smoe     FDPLRLLGTGAFGKVYK----------------------------GV-LSDGTVVAIKQL
IRAK-0_bo_Smoe    LSDDNKLGQGGFGVVYK----------------------------GT-LPDGRRIAIKRL
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    FGEQNKLGQGGFGPVYK----------------------------GV-LTDGSEVAVKKL
IRAK-0_g-2_Smoe   FSDDNKLGQGGFGVVYK----------------------------GT-LPDGRRIAIKRL
IRAK-0_a-2_Smoe   FS--KRIGSGGFGTVFE----------------------------GS-LSDGSRIAVKLL
IRAK-0_d-2_Smoe   FG--NKIGSGGFGTVYY----------------------------GR-LKNGREVAIKVL
IRAK-0_y-2_Smoe   FSSDMVIGKGAFGMVYK----------------------------AR-LPSGEILAIKKG
IRAK-0_m-1_Smoe   YCDDSILGKGSFATVYK----------------------------GV-LHNGRQVAIKQA
IRAK-0_f_Smoe     FSSENKLGQGGFGAVYK----------------------------GV-LPSGTVVAIKEL
IRAK-0_ar-2_Smoe  FSVESKLGQGGFGTVYK----------------------------AT-LNNGSQVAVKKL
IRAK-0_e-1_Smoe   FSDRNKLGQGGFGTVYK----------------------------AAFFGDGTVFAVKRL
IRAK-0_d-1_Smoe   FG--NKIGSGGFGTVYY----------------------------GR-LKNGREVAIKVL
IRAK-0_m-2_Smoe   YCDDSILGKGSFATVYK----------------------------GV-LHNGCQVAIKQA


IRAK-0_i-1_Smoe   DLHSK---QG-QREFVNELSIITSIQHKNLAKLRGYCL-----DR-DDRILVYEFLENKS
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    SLQSN---QG-KREFVNEITIITGIQHRNLVRLKGYCV-----EA-DERLLVYEFLNKGS
IRAK-0_t-2_Smoe   E-GSN---QK-SKDFFAEVGILARTHHWNLVKLLGFCA-----QGPRKRLLVYEYMKNGS
IRAK-0_as_Smoe    SLHSK---QG-KQEFVNELNIITGIRHRNLAKLHGYCV-----EA-NERLLVYEFLENGN
IRAK-0_aq-2_Smoe  LNNTG---QA-EKEFRVEVEAIGKVRHKNLVRLLGYCA-----ES-CYRMLVYEYVDNGN
IRAK-0_af-2_Smoe  LHQTQ---QG-REAFRKEIRILSSVQHRNLVAVRGYCL-----EA-EHPMLVCDYMRNGS
IRAK-0_af-1_Smoe  LHQTQ---QG-REAFRKEIRILSSVQHRNLVAVRGYCL-----EA-EHPMLVCDYMRNGS
IRAK-0_e-2_Smoe   SVGSQ---QG-KMEFVNEIDIITAIRHKNLVMLEGYCC-----EG-NHRLIVYEFLEKGS
IRAK-0_bn_Smoe    SAKSK---QG-QREFRNEIQLLSRLHHRHLVRLLGFCQ-----SG-KNQVLVYEFMENGN
IRAK-0_be_Smoe    KL------------ARDELLVISSASHFNIVGVTGYCF-----NR-KENFLVLEYVPNGS
IRAK-0_bm_Smoe    INVEFKYLVH-QAGFAKEIEILSRARHKNVAGLLGFCN-----SR-DDKFLVSEYVPGPN
IRAK-0_ar-1_Smoe  SLQSN---QG-NREFVNEITIITGIQHRNLVRLKGYCV-----EA-DERLLVYEFLNKGS
IRAK-0_bh_Smoe    FQENERLRRR-RDAFLNEVEILSRVHHKNLVSLIGYCV-----ES-LSLIVVFEYMSGGT
IRAK-0_x_Smoe     IISNN---RS-SELFEKELHLLTRTHHSCLVNLVGYCM-----E---EKLLVFEFMSRGS
IRAK-0_n-1_Smoe   KNCSP---AG-DEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEG-HQRIIVYEFMSNGS
IRAK-0_am_Smoe    -------------QFLNEVKAISSVQHRNLVKLLGCSM-----EG-TERLLVYEFLKNNS
IRAK-0_g-1_Smoe   TTQSQ---KG-KQEFLNEVKLVSSVQHRNLVKLYGCCT-----EE-SERLLVYELLENNS
IRAK-0_au-1_Smoe  VKHTQ---QI-EDDFKREISIISKVRHRNLLAVIGYSL-----ES-DVPMLVCEFIPNGS
IRAK-0_au-2_Smoe  VKHTQ---QI-EDDFKREISIISKVRHRNLLAVIGYSL-----ES-DVPMLVCEFIPNGS
IRAK-0_h_Smoe     -------------QFLNEVKAISSVQHRNLVKLLGCSM-----EG-TERLLVYELLKNNS
IRAK-0_ae-2_Smoe  NHTSK---QS-SRHFYNEVAILSQVNHRNLLRLMGCCV-----DS-DVPILVYEYIPNGN
IRAK-0_ab_Smoe    NNGNA---PR-IQQFLNEVTILSKVNHRNLVKMLGCCI-----ER-EVPLLVYEFVPRGT
IRAK-0_n-2_Smoe   KNCSP---AG-DEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEG-HQRIIVYEFMSNGS
IRAK-0_a-1_Smoe   D-DSN---QG-EKQFKAEVRAICNIHHRNLVSLRGYCS-----QK-PHHFLVYDYVHNGS
IRAK-0_ae-1_Smoe  NHTSK---QS-SRHFYNEVAVLSQVNHRNLLRLMGCCV-----DS-DVPILVYEYIPNGN
IRAK-0_ad_Smoe    DSASL---QG-EKEFQNEMAVIGSIRCSHIVGLMGYCA-----ER-KKRLLVYEYMANRS
IRAK-0_ba_Smoe    LNNSG---QA-EKEFRVEVEAIGRVRHKNLVRLLGYCV-----EI-NYRMLVYEYVDNGN
IRAK-0_b-1_Smoe   NSTTG---PR-IQQFLNEVTILSQVNHRNLVKLLGCCL-----ET-DVPLLVFEFVPNGT
IRAK-0_c-2_Smoe   LNNRG---QA-EKEFRVEVEAIGRVRHKNLVRLLGYCV-----EG-CHRMLVYEYVDNGN
IRAK-0_aa-1_Smoe  NQGNK---QG-IQQFQNEVNILSQVRHPNLVQLLGYCL-----EG-RDLLLVYEFVLNGT
IRAK-0_bb_Smoe    NKM-G---DN-TGDFVNEATLISTVQHRNLVKLYGCCT-----EG-NNWILVFEFMENNN
IRAK-0_bg_Smoe    INNKG---QA-EREFRVEVEAIGRVRHKNLVRLLGYCV-----EG-NYRMLVYEYVDNGN
IRAK-0_t-1_Smoe   E-GSN---QR-SKDFFAEVGILARTHHWNLVKLLGFCA-----QGPRKRLLVYEYMKNGS
IRAK-0_b-2_Smoe   NSTTG---PR-IQQFLNEVTILSQVNHRNLVKLLGCCL-----ET-EVPLLVFEFVPNGT
IRAK-0_aa-2_Smoe  NQGNK---QG-IQQFQNEVNILSQVRHPNLVQLLGYCL-----EG-RDLLLVYEFVLNGT
IRAK-0_aq-1_Smoe  LNNTG---QA-EKEFRVEVEAIGKVRHKNLVRLLGYCA-----ES-CYRMLVYEYVDNGN
IRAK-0_i-2_Smoe   DLHSK---QG-QREFVNELSIITSIQHKNLAKLRGYCL-----DR-DDRILVYEFLENKS
IRAK-0_bj_Smoe    SSKYH---KEDHSVFASDVSSIFAVEHPNLVKLMGCCI-----EA-DEQFLLYEFLENGR
IRAK-0_c-1_Smoe   LNNRG---QA-EKEFRVEVEAIGRVRHKNLVRLLGYCV-----EG-CHRMLVYEYVDNGN
IRAK-0_ac_Smoe    SSKSQ---QG-SREFLNEVTVISSVQHRNLVKLHGCCI-----DG-DHRLLVYEFLENNS
IRAK-0_z-2_Smoe   SLQSS---QG-RQEFVNEISIITSIQHRNLARLKGYCV-----ER-DQRLLVYEFLNNGS
IRAK-0_k_Smoe     NS-SR----C-DAMFDKELELLARTHHSCLVNLFGYCK-----E---ENVLVFEFMSRGT
IRAK-0_y-1_Smoe   KLG------K-AASFGGELKLLSRLHHTNLVNLIGYCK-----Q---EKQLVFEFMANGS
IRAK-0_z-1_Smoe   SLQSS---QG-RQEFVNEISIITSIQHRNLARLKGYCV-----ER-DQRLLVYEFLNNGS
IRAK-0_bq_Smoe    SVASK---QW-EQQFLNEVKVIGSLHSNRLL-----------------------------
IRAK-0_aj_Smoe    SVSSK---QG-EQQFLNEVKVIGSVQHRNLVRLLGCCV-----EG-SERLLVYEFLKNNS
IRAK-0_br_Smoe    DLHSK---QG-QREFVNELSIITSIQHKNLAKLRGYCL-----DR-DDRILVYEFLENKS
IRAK-0_l_Smoe     N-----------------------------------------------------------
IRAK-0_bo_Smoe    TTQSQ---KG-KQEFLNEVKLVSSVQHRNLVKLYGCCT-----EE-SERLLVYELLENNS
IRAK-0_bf_Smoe    -------------------------------------------EE-SHYFLIYEYVANGS
IRAK-0_bk_Smoe    SLHSS---QG-NQEFVNEVNIITGIQHRNLTRLRGYSV-----KG-DERLLVYEYLPNGS
IRAK-0_g-2_Smoe   TTQSQ---KG-KQEFLNEVKLVSSVQHRNLVKLYGCCT-----EE-SERLLVYELLENNS
IRAK-0_a-2_Smoe   D-DSN---QG-EKQFKAEVRAICNIHHRNLVTLRGYCS-----QK-PHHFLVYDYVHNGS
IRAK-0_d-2_Smoe   SATSH---QG-AREFSNEVTLLSRIHHRNLVSFLGFCQ-----EG-KERILVYEFMHIGT
IRAK-0_y-2_Smoe   KLG------K-AASFGGELKLLSRLHHTNLVNLIGYCK-----Q---EKLLVFEFMGNGS
IRAK-0_m-1_Smoe   KASTR----S-GEMFRKELKLLARTHHSCVVNLIGYCE-----Q---EKLLVFEFMSRGT
IRAK-0_f_Smoe     SSKSQ---QG-SREFLNEVTLISSVQHRNLVKLHGCCI-----DG-DHRLLVYEFLENNS
IRAK-0_ar-2_Smoe  SLQSN---QG-NREFVNEITIITGIQHRNLVRLKGYCV-----EA-DERLLVYEFLNKGS
IRAK-0_e-1_Smoe   SVESQ---QG-KREFVNEIDIITGIRHKNLVMLEGYCC-----EG-NHRLIVYEFLEKGS
IRAK-0_d-1_Smoe   SATSH---QG-AREFSNEVTLLSRIHHRNLVSFLGFCQ-----EG-RERILVYEFMHIGT
IRAK-0_m-2_Smoe   KACTR----S-GEMFRKELKLLARTHHSCVLNLIGYCE-----Q---EKLLVFEFMSRGT


IRAK-0_i-1_Smoe   -LDQLLFES-----------------TTGILLDWPTRFQIVLGVANGLAYLHEGSQKQII
IRAK-0_bt_Smoe    ---------------------------------EDTRFKIVEEIARGMCYLHEECSTRVL
IRAK-0_bs_Smoe    -LDRALFSS-----------------ESNAFLDWQSRFQIAIGIARGLAYLHEESHVQVI
IRAK-0_t-2_Smoe   -LERWIFEDD----------------RIPGNISWKLRFNIAIGTARGLNYLHDDCVERII
IRAK-0_as_Smoe    -LDSALFQS-------------------SLALNWQSRFQITLGIARGLAYLHEESHFQII
IRAK-0_aq-2_Smoe  -LEDWLHGFS----------------SQTQAFPWEARMKIALGTAKALTYLHEALEPKVV
IRAK-0_af-2_Smoe  -LDQFLHGS-------------------RGFLTWNQRRKIAIDTAFGLAYLHDESKHRII
IRAK-0_af-1_Smoe  -LDHFLHGS-------------------RGFLTWNQRRKIAIDTAFGLAYLHDESKHRII
IRAK-0_e-2_Smoe   -LDQTLFGK-------------------SLLLDWPARFQIIVGVAKGLAYLHEESHEQVI
IRAK-0_bn_Smoe    -LHDRLLGKY----------------S-GQLLDCYQRLAIAVAVAQGLDYLHSY--AVII
IRAK-0_be_Smoe    -LADHLFSN-------------------ASTLAWSSRLRIAVQVSSALEFLHSYVEPSIT
IRAK-0_bm_Smoe    -LTAFLSGQ------------------RRKEFDWDKRKIVILGVAKGLAYLHSS-GMEII
IRAK-0_ar-1_Smoe  -LDRALFSS-----------------GSNVVLDWHSRFQIAIGIARGLAYLHEESHVQII
IRAK-0_bh_Smoe    -VQGKLHAGT------------------QACLTWETRLTIALDAAQGVEYLHTCCIPQVM
IRAK-0_x_Smoe     -LYDNIFCGS----------------RPDAGLQWICRIKIAAQAARGLEYLHKYACPAII
IRAK-0_n-1_Smoe   -LDDHLFGK------------------FKKNLDWPTRQKIAIGTAKGLAYLHNGAQPAII
IRAK-0_am_Smoe    -LENALFG------------------AVEKPLSWETRHNILLGTARGLAYLHEDSQIRIV
IRAK-0_g-1_Smoe   -LSRVLFQ------------------G-NLCLSWEQRYNVILGVARGLAYLHEDSQVKII
IRAK-0_au-1_Smoe  -LDKWLFRR------------------RENALSWEARRAVAIGVACGLAYLHDESKPSII
IRAK-0_au-2_Smoe  -LDKWLFRR------------------RENALSWEARRAIAIGVACGLAYLHDESKPSII
IRAK-0_h_Smoe     -LENALFG------------------PVEKPLSWETRHNILLGTARGLAYLHEDSQIRIV
IRAK-0_ae-2_Smoe  -LFEHLHK-R------------------PGVLSWSNRLTIAIETAEALAYLHSAAYPPIY
IRAK-0_ab_Smoe    -LYEHLHR-R------------------GDTLSWKNRLRIATETAEALTYLHFAASPPIY
IRAK-0_n-2_Smoe   -LDDHLFGK------------------FKKNLDWPTRQKIAIGTAKGLAYLHNGAQPAII
IRAK-0_a-1_Smoe   -LDRWLFDSS----------------K-AKSLDWNRRFLIVQDIARGLAYLHEECSSTVL
IRAK-0_ae-1_Smoe  -LFEHLHK-R------------------PGVLSWSNRLTIAIETAEALAYLHSAAYPPIY
IRAK-0_ad_Smoe    -LQEALFHD-----------------GYPVELDWKMRYKVILDIAQALAFLHFRCEPPII
IRAK-0_ba_Smoe    -LEQWLHGPA----------------SILNSPTWEVRMKIALGTAKALAYLHEALEPKVV
IRAK-0_b-1_Smoe   -LFEHLQHRR------------------SSILSWERRLQIAIETAEAISYLHSSAAQPIY
IRAK-0_c-2_Smoe   -LEQWLHGPI----------------SRTKSLTWEARMKIVLGTAKALAYLHEALEPKVV
IRAK-0_aa-1_Smoe  -LADHLHGEK------------------GNGLSLETRITIALETAQALAYLHFYVKPPIY
IRAK-0_bb_Smoe    -LHQALLSKYFNLVLPSSSMYSVGPSGRNIHLSWPTRFNICIGVARGLAYLHEESSPRII
IRAK-0_bg_Smoe    -LEQWLHGPV----------------ALSKTPGWDARMKIVLGTAKALAYLHEALEPKVV
IRAK-0_t-1_Smoe   -LERWIFEDD----------------RIPGNISWKVRFNIAIGTARGLSYLHDDCVERII
IRAK-0_b-2_Smoe   -LFEHLQHRR------------------SSILSWERRLQIAIETAEAISYLHSSAAQPIY
IRAK-0_aa-2_Smoe  -LADHLHGEK------------------GNGLSLETRITIALETAQALAYLHFYVKPPIY
IRAK-0_aq-1_Smoe  -LEDWLHGFS----------------SQTQAFPWEARMKIALGTAKALTYLHEALEPKVV
IRAK-0_i-2_Smoe   -LDQLLFES-----------------ATGILLDWPTRFQIVLGVANGLAYLHEGSQKQII
IRAK-0_bj_Smoe    PLSRLLFNPD----------------N-GECLSWQTRMTIAIGIARGVNYLHEEA--HVI
IRAK-0_c-1_Smoe   -LEQWLHGPI----------------SRTKSLTWEARMKIVLGTAKALAYLHEALEPKVV
IRAK-0_ac_Smoe    -LHHVL--------------------------------LICLGIARGLSYLHEDSKPKIV
IRAK-0_z-2_Smoe   -LDRALFSP-----------------K-TSTLNWTSRFHIVTGVARGLAYLHEESHIQII
IRAK-0_k_Smoe     -VHDNIFQSP---------------TSRSGPLEWVSRIRIAAQAARGLEYLHKYASPSII
IRAK-0_y-1_Smoe   -LYDCLFVK-------------------NIKLDWSTRLKIAIQAAHGLEYLHLFADPSII
IRAK-0_z-1_Smoe   -LDRALFSP-----------------K-TSTLNWTSRFHIVTGVARGLAYLHEESHIQII
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    -LEKALLDDML-------------SEEETPRLSLTTRYNILLGTARGLTYLHEDSQIRIV
IRAK-0_br_Smoe    -LDQL-------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    -LSRVLFQ------------------G-NLCLSWEQRYNVILGVARGLAYLHEDSQVKII
IRAK-0_bf_Smoe    -LDKWIYKP-------------------REELNWDTRFKIVEEIARGMCYLHEECSTRVL
IRAK-0_bk_Smoe    -LDRTLTNS-----------------NGKIVLDWPTRYNIAIGVARGLAYLHEESQIQII
IRAK-0_g-2_Smoe   -LSRVLFQ------------------G-NLCLSWEQRYNVILGVARGLAYLHEDSQVKII
IRAK-0_a-2_Smoe   -LDRWLFDSS----------------K-AKSLDWNRRFSIVQDIARGLAYLHEECSSTVL
IRAK-0_d-2_Smoe   -LRDCLYAKE----------------EDRLVLDWTARLKVLLDAAKGLDYLHTGCNPSII
IRAK-0_y-2_Smoe   -LYDCLFVK-------------------NIKLDWSTRLKIVIQAAHGLEYLHLFADPSII
IRAK-0_m-1_Smoe   -LHDNLYSS--------------------HSLEWTTRIKISAQAARGLEYLHRYVSPSVT
IRAK-0_f_Smoe     -LHHVL--------------------------------LICLGIARGLSYLHEDSKPKIV
IRAK-0_ar-2_Smoe  -LDRALFSS-----------------GSNVVLDWHSRFQIAIGIARGLAYLHEESHVQII
IRAK-0_e-1_Smoe   -LDQTLFGK-------------------SLLLDWPARFQIIVGVAKGLAYLHEESHEQVI
IRAK-0_d-1_Smoe   -LRDCLYGKE----------------EDRLVLDWTSRLKVLLDAAKGLDYLHTGCNPSII
IRAK-0_m-2_Smoe   -LHDNLYSS--------------------NSLEWTTRIKISAQAARGLEYLHRYVSPSVT


IRAK-0_i-1_Smoe   HRDIKASNILLDHRLHPKISDFGISKLFNQE-KG--FTSTVIAGTMGYLAP---------
IRAK-0_bt_Smoe    HLDIKPQNLLLDENFGVKIAEFGLS-----------------------------------
IRAK-0_bs_Smoe    HRDIKASNILLDDKLQPKISDFGISKLFDLD-KGFGFTSTKVAGTLGYMAP---------
IRAK-0_t-2_Smoe   HLDLKPENVLLDDGFQPKIADFGLSKLMDRKE-S-QLQLTITRGTPGYVAP---------
IRAK-0_as_Smoe    HRDIKASNVLLDAKLQPKISDFGLSKLFDLD-GE--YGVSKVAGTFGYMAP---------
IRAK-0_aq-2_Smoe  HRDIKASNILVEGDWNAKISDFGLAKLLGSE-KS-H-VTTRVMGTFGYVAP---------
IRAK-0_af-2_Smoe  HCDLKPPNILLDDDMMPRIADFGMARLYEEG-KS-HVTATKMGGTIGYLAPGKKKELICR
IRAK-0_af-1_Smoe  HCDLKPPNILLDDDLMPRIADFGMARLYEEG-KS-HVTATKMGGTIGYLAPGKKKERISR
IRAK-0_e-2_Smoe   HRDIKASNILLDKMLQPKISDFGISKLAGVE-KE--NTTTRVAGTVGYMAP---------
IRAK-0_bn_Smoe    HRDLKPSNILLDGNLTAKISDFGISKVSPEF-DT-HV-STKPAGTAGYLDP---------
IRAK-0_be_Smoe    HGHVSSDNILLDKSWNAKLAGFGSSR----------------------------------
IRAK-0_bm_Smoe    HGSLKPSNILIDDDFTPKLTDHGLYRLLQQT-SS-Q-A--RDVRNAVYDPP---------
IRAK-0_ar-1_Smoe  HRDIKASNILLDDKLQPKISDFGISKLFDLD-KGFGFTSTKVAGTLGYMAP---------
IRAK-0_bh_Smoe    HRDLKSSNILLSDKMMAKVGDFGISKFLSPD-D--DI-SNSVKGTPGYVDP---------
IRAK-0_x_Smoe     HRDVKSANILLDDDWNAHVSDFGLSLFGPLGSAT-HLSNMTIVGTPGYLDP---------
IRAK-0_n-1_Smoe   HRDIKGGNILLDSEFNAKVADFGLAKFAPEG-MT-H-MTTGVAGTQGYVAP---------
IRAK-0_am_Smoe    HRDIKPSNILLDEFYEAKIADFGLARLFESS-HQLEVLTTKAAGTYGYMTP---------
IRAK-0_g-1_Smoe   HRDIKAGNVLLDEKFEAKIADFGLARLYSDE-R--S-INTQIAGTLGYMAP---------
IRAK-0_au-1_Smoe  HLDVKPGNILLDEDFNPRLADFGLARLYDEK-ES-HVTATRLKGTAGYLAP---------
IRAK-0_au-2_Smoe  HLDVKPGNILLDEDFNPRLADFGLARLYDEK-ES-HVTATRLKGTAGYLAP---------
IRAK-0_h_Smoe     HRDIKPSNILLDEFYEAKIADFGLARLFESS-HQLEVLTTKAAGTYGYMAP---------
IRAK-0_ae-2_Smoe  HRDVKSANILLDNAFTTKVADFGLSRLVPVD-VT-HV-STMVQGTPGYVDP---------
IRAK-0_ab_Smoe    HRDVKSSNILLDEKLTAKVADFGISKLVPID-ST-HI-STTLHGTPGYIDP---------
IRAK-0_n-2_Smoe   HRDIKGGNILLDSEFNAKVADFGLAKFAPEG-MT-H-MTTGVAGTQGYVAP---------
IRAK-0_a-1_Smoe   HLDIKPQNVLLDESFTAKISDFGLSRMLGGDGRT-DNAVTAIKGTPGYMAP---------
IRAK-0_ae-1_Smoe  HRDVKSANILLDNAFTTKVADFGLSRLVPVD-VT-HV-STMVQGTPGYVDP---------
IRAK-0_ad_Smoe    HGDIKPSNVLLDDKLCARLADFGLA-----------------------------------
IRAK-0_ba_Smoe    HRDIKASNILLDAHWNAKISDFGLAKLLGSD-NS-H-VKTRVMGTFGYVAP---------
IRAK-0_b-1_Smoe   HRDVKSTNILLDEKFTAKVADFGISKLVSLE-AT-HV-STTVHGTPGYIDP---------
IRAK-0_c-2_Smoe   HRDIKSSNILIDSTYNARISDFGLAKLLGAG-KS-H-VTTRVMGTFGYVAP---------
IRAK-0_aa-1_Smoe  HRDVKTSNILLDKDFKAKVADFGLSRLTHLD-AT-HI-STAPQGTPGYLDP---------
IRAK-0_bb_Smoe    HRDIKATNVLLDQALVAKIADFGLARLFEDH-QS-HI-STRVAG----------------
IRAK-0_bg_Smoe    HRDIKASNILLDSRWNSKVSDFGLAKLLGSE-KS-H-VTTRVMGTFGYVAP---------
IRAK-0_t-1_Smoe   HLDLKPENVLLDDGFQPKIADFGLSKLMNRKE-S-QLQLTITRGTPGYVAP---------
IRAK-0_b-2_Smoe   HRDVKSTNILLDEKFTAKVADFGISKLVSLE-AT-HV-STTVHGTPGYIDP---------
IRAK-0_aa-2_Smoe  HRDVKTSNILLDKDFKAKVADFGLSRLTHLD-AT-HI-STAPQGTPGYLDP---------
IRAK-0_aq-1_Smoe  HRDIKASNILVEGDWNAKISDFGLAKLLGSE-KS-H-VTTRVMGTFGYVAP---------
IRAK-0_i-2_Smoe   HRDIKASNILLDHRLHPKISDFGISKLFNQE-KG--FTSTVIAGTMGYLAP---------
IRAK-0_bj_Smoe    HGDIQASNIIIDENFTPKISDFGLTSLLPDED-S-Y-INSRFSGTLGYIAP---------
IRAK-0_c-1_Smoe   HRDIKSSNILIDSTYNARISDFGLAKLLGAG-KS-H-VTTRVMGTFGYVAP---------
IRAK-0_ac_Smoe    HRDIKAHNVLLDRNMTPKIADFGLAKLFQDH-ET-HV-STRVAGTIGYLSP---------
IRAK-0_z-2_Smoe   HRDIKASNILLDDKMQPKISDFGISKLFDMD-KG--FTSTKVAGTVGYMAP---------
IRAK-0_k_Smoe     HRDIKSANILIDFDWNAHISDFGISLCGPQDNAT-HLSNMTIVGTPGYLDP---------
IRAK-0_y-1_Smoe   HRDVKSSNILLDEGFNAHVADFGASTLGPTENST-HVTSTSLVGTPGYVDP---------
IRAK-0_z-1_Smoe   HRDIKASNILLDDKMQPKISDFGISKLFDMD-KG--FTSTKVAGTVGYMAP---------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    HRDIKPSNILLDETFEAKISDFGLARLYEED-EATEIITTKVAGTYGYMAP---------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    HRDIKAGNVLLDEKFEAKIADFGLARLYSDE-R--S-INTQIAGTLGYMAP---------
IRAK-0_bf_Smoe    HLDIKPQNLLLDENFGVKIAEFGLS-----------------------------------
IRAK-0_bk_Smoe    HRDIKASNILLDKDLTPKISDFGISKLFDQD-RT--SVDTKIAGTYGYMAP---------
IRAK-0_g-2_Smoe   HRDIKAGNVLLDEKFEAKIADFGLARLYSDE-R--S-INTQIAGTLGYMAP---------
IRAK-0_a-2_Smoe   HLDIKPQNVLLDESFTAKISDFGLSRILGGDGRT-DNAVTAIKGTPGYMAP---------
IRAK-0_d-2_Smoe   HRDVKSSNILISDKKTGKVADFGLSKMTSEG-SS-LV-STTVKGTVGYLDP---------
IRAK-0_y-2_Smoe   HRDVKSSNILLDEGFNAHVADFGASTLGPTENST-HVTSTSLVGTPGYVDP---------
IRAK-0_m-1_Smoe   HRDVKSSNILLDCDWNAKVSDFGLSVCGPQDNAT-HLSNLTIVGTPGYLDP---------
IRAK-0_f_Smoe     HRDIKAHNVLLDRNMTPKIADFGLAKLFQDH-ET-HV-STRVAGTIGYLSP---------
IRAK-0_ar-2_Smoe  HRDIKASNILLDDKLQPKISDFGISKLFDLD-KGFGFTSTKVAGTLGYMAP---------
IRAK-0_e-1_Smoe   HRDIKASNILLDKMLQPKISDFGISKLAGVD-RE--NTTTRLAGTVGYMAP---------
IRAK-0_d-1_Smoe   HRDVKSSNILISDKKTGKVADFGLSKMTSEG-SS-LV-STTVKGTVGYLDP---------
IRAK-0_m-2_Smoe   HRDVKSSNILLDCDWNAKVSNFGLSVCGPQDNAT-HLSNLTIVGTPGYLDP---------


IRAK-0_i-1_Smoe   -------------EYV----------------LGGLLTVKADVYSFGVLTLEIVSG----
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    -------------EYT----------------SRGRLTAKADVFSYGILVLEIASG----
IRAK-0_t-2_Smoe   -------------ECI----------------QEGTVTEKTDVFGFGVLLLEIITG----
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  -------------EYA----------------STGLLNERSDVYSFGVLLMELITGRD--
IRAK-0_af-2_Smoe  ILELGFIDNSSLAEYA----------------MHYQLSDKADVYSYGVVLLEIISG----
IRAK-0_af-1_Smoe  VLDLGFIDISSLAEYA----------------MHYQLSDKADVYSYGVVLLEIISG----
IRAK-0_e-2_Smoe   -------------EYV----------------LRGRLSSKVDVFSFGVLVLEIISG----
IRAK-0_bn_Smoe    -------------EYF----------------LRRQLTTASDVYSFGVVLLELITG----
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    -------------EAS----------------TGTLMSSKGDSYGFGVFLIQMITGQPP-
IRAK-0_ar-1_Smoe  -------------EYA----------------TRGRLTTKADVFSYGILVLEIASG----
IRAK-0_bh_Smoe    -------------EYGSFSLCHSCLYCIHRYFATNRFSEKSDVYSFGVVLLELICG----
IRAK-0_x_Smoe     -------------EYG----------------LSMKLTSKSDVYSFGVVLLELLSGAKP-
IRAK-0_n-1_Smoe   -------------EYV----------------LYNQLTDRSDVYSFGIVFLELLSG----
IRAK-0_am_Smoe    -------------EYA----------------LNGQLSDKIDVYSYGIVIL---------
IRAK-0_g-1_Smoe   -------------EYA----------------LHGHLTDKADVFSFGILSLEIVSG----
IRAK-0_au-1_Smoe  -------------EYA----------------MHLQLSDKVDVYSFGVVLLELLSG----
IRAK-0_au-2_Smoe  -------------EYA----------------MHLQLSDKVDVYSFGVVLLELLSG----
IRAK-0_h_Smoe     -------------EYA----------------LNGQLSDKIDVYSYGIV-----------
IRAK-0_ae-2_Smoe  -------------EYH----------------QTYQLTDKSDVYSFGVVLLEMVTGRK--
IRAK-0_ab_Smoe    -------------QYQ----------------QSYQLTDKSDVYSFGVVILELITGQM--
IRAK-0_n-2_Smoe   -------------EYV----------------LYNQLTDKSDVYSFGIVFLELLSG----
IRAK-0_a-1_Smoe   -------------EWL----------------TQAKVTKALDVYSFGIVVLEIIT-----
IRAK-0_ae-1_Smoe  -------------EYH----------------QTYQLTDKSDVYSFGVVLLEMVTGRK--
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    -------------EYA----------------NTGLLNERSDVYSFGVLLMEMITGRD--
IRAK-0_b-1_Smoe   -------------QYQ----------------QNYQLTDKSDVYSFGVVLLELITGQK--
IRAK-0_c-2_Smoe   -------------EYA----------------NTGLLNERSDVYSFGVLLMEVVTGRD--
IRAK-0_aa-1_Smoe  -------------DYH----------------ESYQLTDKSDVYSFGVVLLELISR----
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    -------------EYA----------------NTGLLNERSDVYSFGVLLMEVVTGRD--
IRAK-0_t-1_Smoe   -------------ECI----------------QEGTVTEKTDVFGFGVLLLEIITG----
IRAK-0_b-2_Smoe   -------------QYQ----------------QNYQLTDKSDVYSFGVVLLELITGQK--
IRAK-0_aa-2_Smoe  -------------DYH----------------ESYQLTDKSDVYSFGVVLLELISR----
IRAK-0_aq-1_Smoe  -------------EYA----------------STGLLNERSDVYSFGVLLMELITGRD--
IRAK-0_i-2_Smoe   -------------EYV----------------LGGLLTVKADVYSFGVLTLEIVSG----
IRAK-0_bj_Smoe    -------------EVA-----------------QGKLTDKADVFSFGVLLLEIVSGRNNF
IRAK-0_c-1_Smoe   -------------EYA----------------NTGLLNERSDVYSFGVLLMEVVTGRD--
IRAK-0_ac_Smoe    -------------EYA----------------MRGQLTEKADVYSFGVLALEIVSG----
IRAK-0_z-2_Smoe   -------------EYA----------------TRGRLSSKADVFSFGILALEIVSG----
IRAK-0_k_Smoe     -------------EYG----------------TSSQLTLKSDVYSFGVVLLELLSGRK--
IRAK-0_y-1_Smoe   -------------EYF----------------QTMQLSPKSDVYSFGVVILELFTG----
IRAK-0_z-1_Smoe   -------------EYA----------------TRGRLSSKADVFSFGILALEIVSG----
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    -------------EYA----------------FHGHLSEKADVFTFGVVVLETLAG----
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    -------------EYA----------------LHGHLTDKADVFSFGILSLEIVSG----
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    -------------EYA----------------MGGRLTVKADVFSFGVLLLEIIC-----
IRAK-0_g-2_Smoe   -------------EYA----------------LHGHLTDKADVFSFGILSLEIVSG----
IRAK-0_a-2_Smoe   -------------EWL----------------TQTKVTKALDVYSFGIVVLEIIT-----
IRAK-0_d-2_Smoe   -------------EYY----------------MNQRLTEKSDVYSFGIVLL---------
IRAK-0_y-2_Smoe   -------------EYF----------------QTMQISPKSDVYSFGVVILELFTG----
IRAK-0_m-1_Smoe   -------------DYG----------------NSSQLTTTSDVYSFGVVLLELMSGQK--
IRAK-0_f_Smoe     -------------EYA----------------MRGQLTEKADVYSFGVLALEIVSG----
IRAK-0_ar-2_Smoe  -------------EYA----------------TRGRLTTKADVFSYGILVLEIASG----
IRAK-0_e-1_Smoe   -------------EYV----------------LRGRLSSKADVFSFGVLVLEIISG----
IRAK-0_d-1_Smoe   -------------EYY----------------MNQRLTEKSDVYSFGIVLL---------
IRAK-0_m-2_Smoe   -------------EYG----------------NSSQLTTTSDVYSFGVVLLELMSGQK--


IRAK-0_i-1_Smoe   ----------------Q
IRAK-0_bt_Smoe    ----------------R
IRAK-0_bs_Smoe    ----------------R
IRAK-0_t-2_Smoe   ----------------C
IRAK-0_as_Smoe    ----------------E
IRAK-0_aq-2_Smoe  ----------------P
IRAK-0_af-2_Smoe  ----------------R
IRAK-0_af-1_Smoe  ----------------R
IRAK-0_e-2_Smoe   ----------------R
IRAK-0_bn_Smoe    ----------------Q
IRAK-0_be_Smoe    -----------------
IRAK-0_bm_Smoe    ---------------WF
IRAK-0_ar-1_Smoe  ----------------R
IRAK-0_bh_Smoe    ----------------R
IRAK-0_x_Smoe     ---------------MD
IRAK-0_n-1_Smoe   ----------------R
IRAK-0_am_Smoe    ----------------E
IRAK-0_g-1_Smoe   ----------------R
IRAK-0_au-1_Smoe  ----------------R
IRAK-0_au-2_Smoe  ----------------R
IRAK-0_h_Smoe     ----------------I
IRAK-0_ae-2_Smoe  ----------------P
IRAK-0_ab_Smoe    ----------------P
IRAK-0_n-2_Smoe   ----------------R
IRAK-0_a-1_Smoe   ----------------G
IRAK-0_ae-1_Smoe  ----------------P
IRAK-0_ad_Smoe    ----------------R
IRAK-0_ba_Smoe    ----------------P
IRAK-0_b-1_Smoe   ----------------P
IRAK-0_c-2_Smoe   ----------------P
IRAK-0_aa-1_Smoe  ----------------K
IRAK-0_bb_Smoe    ----------------T
IRAK-0_bg_Smoe    ----------------P
IRAK-0_t-1_Smoe   ----------------C
IRAK-0_b-2_Smoe   ----------------P
IRAK-0_aa-2_Smoe  ----------------K
IRAK-0_aq-1_Smoe  ----------------P
IRAK-0_i-2_Smoe   ----------------Q
IRAK-0_bj_Smoe    EPDLPMETVFLVQWTWK
IRAK-0_c-1_Smoe   ----------------P
IRAK-0_ac_Smoe    ----------------R
IRAK-0_z-2_Smoe   ----------------R
IRAK-0_k_Smoe     ----------------P
IRAK-0_y-1_Smoe   ----------------R
IRAK-0_z-1_Smoe   ----------------R
IRAK-0_bq_Smoe    ----------------P
IRAK-0_aj_Smoe    ----------------R
IRAK-0_br_Smoe    ----------------L
IRAK-0_l_Smoe     ----------------R
IRAK-0_bo_Smoe    ----------------R
IRAK-0_bf_Smoe    ----------------R
IRAK-0_bk_Smoe    ----------------G
IRAK-0_g-2_Smoe   ----------------R
IRAK-0_a-2_Smoe   ----------------G
IRAK-0_d-2_Smoe   ----------------E
IRAK-0_y-2_Smoe   ----------------R
IRAK-0_m-1_Smoe   ----------------P
IRAK-0_f_Smoe     ----------------R
IRAK-0_ar-2_Smoe  ----------------R
IRAK-0_e-1_Smoe   ----------------R
IRAK-0_d-1_Smoe   ----------------E
IRAK-0_m-2_Smoe   ----------------P