Protein (view, download) , Domain (view, download)
M04C9.5_Cele     MTPRIRRKTNI--------A--SFRIFHISGDYILCIVMSIYFLL--S-----SK-TDNI
DDB0229430_Ddis  M-----------------------------------------------------------
MAK_Hsap         -----------------------------------------------------------M
ICK_Hsap         -----------------------------------------------------------M
CG4588_Dmel      -----------------------------------------------------------M
ICK_Mmus         -----------------------------------------------------------M
MAK_Mmus         -----------------------------------------------------------M
IME2_Scer        MVEKRSRQSSS--------SGSEFSVP---PDV------DNPP-L--S-----IPLKTLS
MAK_Spur         M-----------------------------------------------------------
CC1G_11298_Ccin  MYNNTNANPTRNRQPPLRETITVVGIPSVSIDN------DRLVVG--S-----SQ-TSST
AqueK132_Aque    MSV--------------------------------------------------------L
MAK_d_Smoe       MHKTSI--------------------------------MQRYVLL-CFSGAN-SD-FVVL
MAK_c_Smoe       MHKTSI--------------------------------MQRYVLLLCFTGAN-SD-FVVL
MAK_e_Smoe       MQRYITKLSH--------------------------------------SQSFFLP-FFSF
MAK_b_Smoe       M-----------------------------------------------------------
MAK_a_Smoe       MQRYITKLSH--------------------------------------SQSFFLP-FFSF
GK041_Glam       M-----------------------------------------------------------
GK039_Glam       M-----------------------------------------------------------


M04C9.5_Cele     FRYLM--TKRLGDGTFGEVMLAKK------------------------------------
DDB0229430_Ddis  EKYQF--IKQVGDGAYGDVIKAID------------------------------------
MAK_Hsap         NRYTT--MRQLGDGTYGSVLMGKS------------------------------------
ICK_Hsap         NRYTT--IRQLGDGTYGSVLLGRS------------------------------------
CG4588_Dmel      NRYIT--LTQLGDGTYGTVVLGQR------------------------------------
ICK_Mmus         NRYTT--IKQLGDGTYGSVLLGRS------------------------------------
MAK_Mmus         NRYTT--MKQLGDGTYGSVLMGKS------------------------------------
IME2_Scer        DRYQL--IEKLGAGSFGCVTLAKAQFPLSN---------ILGKQHDIRGTLMDQPKNGHQ
MAK_Spur         NQYQV--TKQLGDGTYGSVILGCR------------------------------------
CC1G_11298_Ccin  RSYTP--IKVLGDGSFGTVWLCDWHTTLPPNTPLSPMQCGQG-----------------A
AqueK132_Aque    QKYTF--LKVLGDGTFGVVSLAKE------------------------------------
MAK_d_Smoe       SRYKV--IKQLGDGTYGTVWKAVN------------------------------------
MAK_c_Smoe       SRYKV--IKQLGDGTYGTVWKAVN------------------------------------
MAK_e_Smoe       KRYQV--IKQVGDGTYGSVWKAID------------------------------------
MAK_b_Smoe       TRYSIDYSTRLGRGTGGTVREGIN------------------------------------
MAK_a_Smoe       KRYQV--IKQVGDGTYGSVWKAID------------------------------------
GK041_Glam       ENYTV--ITELGSGNYGTVYKAREN-----------------------------------
GK039_Glam       DAYTP--VRRVGSGTYGDVLHAVD------------------------------------
                   *       :* *  * *

M04C9.5_Cele     ---IDTGDRVAIKRMKKKFY-SWEEAMSLREVK-------------------SLKKL-NH
DDB0229430_Ddis  ---VKTGEIVAIKRMKKKFS-DWKECIQLREIK-------------------ALKKL-KH
MAK_Hsap         ---NESGELVAIKRMKRKFY-SWDECMNLREVK-------------------SLKKL-NH
ICK_Hsap         ---IESGELIAIKKMKRKFY-SWEECMNLREVK-------------------SLKKL-NH
CG4588_Dmel      ---KDTGEKVAIKRMKRKYY-SWEEAMNLREVK-------------------SLKKL-SH
ICK_Mmus         ---IESGELIAIKKMKRKFY-SWEECMNLREVK-------------------SLKKL-NH
MAK_Mmus         ---NESGELVAIKRMKRKFY-SWDECMNLREVK-------------------SLKKL-NH
IME2_Scer        NYITKTQGVVAIKTMMTKLH-TLQDYTRVREIK-------------------FILAIPAN
MAK_Spur         ---FDNGEKVAIKKMKKKFY-SWNECMELREVK-------------------SLKKL-NH
CC1G_11298_Ccin  RPEWAGKRLVAVKRMKKRWEGGWDECQKLKELE-------------------SLRAIPFH
AqueK132_Aque    ---KETGNMVAIKKMKQDFL-SWEECLKLKEVQVSELFVSPYIYKYGRNDVHALQRL-KH
MAK_d_Smoe       ---KVTNETVAIKKMKRKYL-SWDECMNLREVK-------------------SLRKL-NH
MAK_c_Smoe       ---KVTNETVAIKKMKRKYL-SWDECMNLREVK-------------------SLRKL-NH
MAK_e_Smoe       ---RCTNEFVAIKKMKTKFH-GWEECMNLREVK-------------------CLQRL-DH
MAK_b_Smoe       ---LDTMEKVAIKEMVEHLN-LHEETKLVY--G-------------------LLQEC-QH
MAK_a_Smoe       ---RCTNEFVAIKKMKTKFH-GWEECMNLREVK-------------------CLQRL-DH
GK041_Glam       ----KKGTLVAIKHMKQKYK-SWSECVTLKEVK-------------------SLIRMKEH
GK039_Glam       ----TKGDFVAIKIMNSHTL-CVSDPLQLPEVA-------------------TLRRLPPH
                          :*:* *        .:   :                        :     :

M04C9.5_Cele     PNIIKLREVIR--ENDILYFVFEFM----------------QE-NLYELMK-DRD----R
DDB0229430_Ddis  PNIVKLLEIIL--ERDELFFVFEYL----------------EN-NLYESIK-DRT----K
MAK_Hsap         ANVIKLKEVIR--ENDHLYFIFEYM----------------KE-NLYQLMK-DRN----K
ICK_Hsap         ANVVKLKEVIR--ENDHLYFIFEYM----------------KE-NLYQLIK-ERN----K
CG4588_Dmel      PNIVKLKEVIR--ENDTLYFVFEYM----------------KE-NLYQMIK-DRD----T
ICK_Mmus         ANIVKLKEVIR--ENDHLYFIFEYM----------------KE-NLYQLIK-ERN----K
MAK_Mmus         ANVIKLKEVIR--ENDHLYFVFEYM----------------KE-NLYQLMK-DRN----K
IME2_Scer        DHLIQIFEVFIDSENYQLHIVMECM----------------EQ-NLYQMMK-HRRR---R
MAK_Spur         ANIVKLKEVIR--EDNILYFVFEYM----------------TE-NLYELMK-GRD----R
CC1G_11298_Ccin  PNIIPLYDFFLLPTSKELYFVFESM----------------E-GNLYHLIK-ARKG---R
AqueK132_Aque    VNIIKATEIFR--DNNTLYFVFEYM----------------RQ-NLYELIK-SRGS---N
MAK_d_Smoe       PNIVKLKEVIR--ENNELFFVFEYMVLYFCFPFSATHFYLQEC-NLYQMMK-DRQ----K
MAK_c_Smoe       PNIVKLKEVIR--ENNELFFVFEYMVLYFCFPFSATHVYLQEC-NLYQMMK-DRQ----K
MAK_e_Smoe       PNIVQLKEVIW--EHGELFLVFEYM----------------EC-NLYQVMK-DRS----K
MAK_b_Smoe       ENIVKLLDVGS--IGGKTYMVFEHM----------------FG-DLYKFKK-RLGMLMKR
MAK_a_Smoe       PNIVQLKEVIW--EHGELFLVFEYM----------------EC-NLYQVMK-DRS----K
GK041_Glam       PNIVKLMEVV--RQKEDLYFVFEYI----------------NSGNLFDFVVQQRSAG--I
GK039_Glam       PNIIRLIRVVV--TRDHTHLIFEYA----------------GGGTLLNFLR-S-SG----
                  :::    .         .:::*                      * .

M04C9.5_Cele     YFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNG--------------------
DDB0229430_Ddis  LLPETTIRNIIYQILQALHFMHTNGFFHRDLKPENIMLVG--------------------
MAK_Hsap         LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMG--------------------
ICK_Hsap         LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMG--------------------
CG4588_Dmel      HLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSG--------------------
ICK_Mmus         LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMG--------------------
MAK_Mmus         LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMG--------------------
IME2_Scer        VFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIG------
MAK_Spur         LLPEPVIRNIVYQILQGMAYIHKNGFFHRDMKPENLLCCG--------------------
CC1G_11298_Ccin  PLAGGLVSSIFQQITLGLDHIHTHGYFHRDMKPENVLVTTVGLF-DYTPVSPIAPPNAPK
AqueK132_Aque    LFPEHVVRNISYQIIQAVSYMHSQGLFHRDLKPENILCQG--------------------
MAK_d_Smoe       LFPEAKIRNWCFQVLQGLAYMHREGYFHRDLKPENLLVT---------------------
MAK_c_Smoe       LFPEAKIRNWCFQVLQGLAYMHREGYFHRDLKPENLLVT---------------------
MAK_e_Smoe       MLSEERIRIWSFQVLRALDYMHQHGIFHRDLKPENLLVSD--------------------
MAK_b_Smoe       TLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKE-------------------
MAK_a_Smoe       MLSEERIRIWSFQVLRALDYMHQHGIFHRDLKP---------------------------
GK041_Glam       KISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGT-----------------
GK039_Glam       PLKEHMLRNIAFRILQGLYHIHTNSVIHRDLKLENILLTSETGD----------------
                  :          ::  .: .:* .. .*:*:*

M04C9.5_Cele     -----TELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRST-SYNSPIDMWALGCI
DDB0229430_Ddis  ------ERLKIADFGLAREIESKPPFTDYISTRWYRAPEVLLRCT-YYNAPIDIWAVGAI
MAK_Hsap         -----PELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSS-VYSSPIDVWAVGSI
ICK_Hsap         -----PELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRST-NYSSPIDVWAVGCI
CG4588_Dmel      -----PDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHST-NYGSTIDLWAMGCI
ICK_Mmus         -----PELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRST-NYSSPIDIWAVGCI
MAK_Mmus         -----PELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSS-VYSSPIDVWAVGSI
IME2_Scer        -YQ-DNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSG-YYSKPLDIWAFGCV
MAK_Spur         -----PELIKIADFGLARETRSRPPYTDYVSTRWYRAPEVLLRST-KYSSPIDMWAVGCI
CC1G_11298_Ccin  ERD-VVTIIKLADFGLARETRSRPPYTEYVSTRWYRAPEVLLLSR-EYSNPVDLWALGTI
AqueK132_Aque    -----HELIKLADFGQAREIRSRPPYTDYVSTRWYRAPEVQLGSK-NYNSPIDIWAVACI
MAK_d_Smoe       -----VDVIKIADFGLAREVRSRPPYTNYVSTRWYRAPEVLLQSS-LYNSAVDMWAMGAI
MAK_c_Smoe       -----VDVIKIADFGLAREVRSRPPYTNYVSTRWYRAPEVLLQSS-LYNSAVDMWAMGAI
MAK_e_Smoe       ------EAIKVADFGLAREVYSVAPYTDYVATRWYRAPEVLLQAP-SYSYAIDIWAMGAI
MAK_b_Smoe       -----GTKVKLCDFDHARRVTTPPRDPETIGTLAYNAPEIILGDTQELGSGVDVWGAGVI
MAK_a_Smoe       ----------------------------------------------------DIWAMGAI
GK041_Glam       ----GTRCVKIADLGCAKSLLERPPHTVYVGTRWYRAVELFLKDS-SYSAKNDIWACACI
GK039_Glam       -ANGDIVGVKIADFGLSRAQGSRQ-NTDYVSTRWYRAPELLLHYS-GYGPPIDIWAAGCC
                                                                     *:*. .

M04C9.5_Cele     MAELYILRPLFPGTSE---MDQLFKIISILGTPNKD-----------------EWPEGYQ
DDB0229430_Ddis  MAELYSLKPMFPGSSE---IDQLFKICTIMGSPTSA-----------------TWIDGIK
MAK_Hsap         MAELYMLRPLFPGTSE---VDEIFKICQVLGTPKKS-----------------DWPEGYQ
ICK_Hsap         MAEVYTLRPLFPGASE---IDTIFKICQVLGTPKKT-----------------DWPEGYQ
CG4588_Dmel      MAELYTFRPLFPGSSE---VDQLFKICSVLGTPDKD-----------------DWPDGYR
ICK_Mmus         MAEVYTLRPLFPGASE---IDTIFKICQVLGTPKKT-----------------DWPEGYQ
MAK_Mmus         MAELYTFRPLFPGTSE---VDEIFKICQVLGTPKKS-----------------DWPEGYQ
IME2_Scer        AVEVTVFRALFPGANE---IDQIWKILEVLGTPIKRS-DFVNTNHITAPPPGGFWDDASN
MAK_Spur         MAELYTLRPLFPGSSE---VDEIFKITTVLGTPKKE-----------------EWVEGFR
CC1G_11298_Ccin  MAELVNLRPLFPGSDQ---VDQVARVCEVLGDPAEDYRD--NGGNV---VGGGQWPHGVS
AqueK132_Aque    MSEVYSGRPLFPGSGT---IDQVYKICGVLGTPTKA-----------------TWGEGVG
MAK_d_Smoe       MAELFNLRPIFPGASE---ADEIYKICSVLGNPSQA-----------------TWPDGMK
MAK_c_Smoe       MAELFNLRPIFPGASE---ADEIYKICSVLGNPSQA-----------------TWPDGMK
MAK_e_Smoe       MAELFNLQPLFPGASE---ADEIYKICSVLGSPNYH-----------------TWPDGMQ
MAK_b_Smoe       LAELVLGYNPFSVVRESHAARELYRVVEEIKER---------------------------
MAK_a_Smoe       MAELFNLQPLFPGASE---ADEIYKICSVLGSPNYH-----------------TWPDGMQ
GK041_Glam       LCEILLMKPLFPGAND---IDMLNLITSTLGSPTRE-----------------DWPAGYA
GK039_Glam       FAELLTGDPLFPGDTE---IQQLQLICAFLK-PLKPD-----------------ACKGAM
                   *:      *.          :  :   :

M04C9.5_Cele     LASAMNFRFQQVVAT---PMEQ----VVN-----------TI-SKEGMKLMMDMMLWNPE
DDB0229430_Ddis  LANSMGFTFPNVQPPSINPLST----LLP-----------NA-NQDAIELITDLLQYDPL
MAK_Hsap         LASSMNFRFPQCVPI---NLKT----LIP-----------NA-SNEAIQLMTEMLNWDPK
ICK_Hsap         LSSAMNFRWPQCVPN---NLKT----LIP-----------NA-SSEAVQLLRDMLQWDPK
CG4588_Dmel      LASMIHFRYPDCIKV---PLSS----VVS-----------RC-SQNGLDLLEDMLAYDPD
ICK_Mmus         LSSAMNFLWPQCIPN---NLKT----LIP-----------NA-SSEAIQLLRDLLQWDPK
MAK_Mmus         LASSMNFRFPQCIPI---NLKT----LIP-----------NA-SSEAIQLMTEMLNWDPK
IME2_Scer        LVHKLNLKLPYVEGS---SLDH----LLS-----------SSQLSDLSEVVKKCLRWDPN
MAK_Spur         LASQMNFKFPQCVAM---PLKT----IIP-----------NA-SPESIHLIRDMLLWDPQ
CC1G_11298_Ccin  LARDVGFQFPRIEPK---DIFS----LFD-----------ASVPRSLIQCIRDLLRWDPA
AqueK132_Aque    LAVSMSIRLPIMVPT---PLSA----LVP-----------TA-SDDGISVMKEMLQWNPR
MAK_d_Smoe       LAKCMNFRFPQ-----------------------------------------AMFAWDPL
MAK_c_Smoe       LAKCMNFRFPQFVPA---NLSA----LVP-----------SA-SAEAIDLMKAMFAWDPL
MAK_e_Smoe       LAVRKGFRFPQFAPA---GLQS----LIP-----------SA-SPAAVDMISAMLCWDPN
MAK_b_Smoe       --------------------------LHR-----------EIGDEDILELLDNMLVWEPE
MAK_a_Smoe       LAVRKGFRFPQFAPA---GLQS----LIP-----------SA-SPAAVDMISAMLCWDPN
GK041_Glam       LAERIGYKFPRATQSRQEKLRY----LFP-----------NV-TEDCINLLSRMFEFDQN
GK039_Glam       HA------LPRFITE---NMTVSDADIYTLAEAREALRRELGCSHVLADLLAHMLAWNPE
                                                                       : ::

M04C9.5_Cele     KRPNANQSLRYKYFQV-AEKLGAPVVSQP-APG--SIRKTS-------------------
DDB0229430_Ddis  KRPTPLQALQHRYFKV-SIPSSI-LL----------------------------------
MAK_Hsap         KRPTASQALKHPYFQV-GQVLGPSSNHLE-SKQ--SLNK---------------------
ICK_Hsap         KRPTASQALRYPYFQV-GHPLGSTTQNLQ-DSE--KPQKGI-L-EK--------------
CG4588_Dmel      KRPTAQQSLKYPYFHA-LKRISPTAATKA-N-V--RLNSKYAA-SN------GHPVQSVS
ICK_Mmus         KRPTASQALRYPYFQI-GHPLGIISKDSG------KPQREV-Q-DK--------------
MAK_Mmus         KRPTASQALKHPYFQV-GQVLGSSAHHLD-TKQ--TLHK---------------------
IME2_Scer        ERATAQELCEMPFFEN-TVASQVDARGNV------TNTEQA-LIFA--------------
MAK_Spur         KRPTAAQCLKYKYFQV-GQNLGAKAQP-P-AQQ--HQQNQM-A-QR--------------
CC1G_11298_Ccin  KRLTSKQCLDHLYLRE-TIHRNNIPMPSGLRAASVSQTSIP-MMSSHLNGSSSHPSLSSH
AqueK132_Aque    RRPTAKQVLMHKYFQV-GHPYHTPSQVTS-TTG--HSTKNT-L-TN--------------
MAK_d_Smoe       KRPTPSQALQHPFFQV-CSLSMFCTEA---------------------------------
MAK_c_Smoe       KRPTPSQALQHPFFQV-CSLSMFCTEA---------------------------------
MAK_e_Smoe       RRPTAYQLRQHPFFYQFGLCIPPPIE----------------------------------
MAK_b_Smoe       ERWSAERALSSSFFED-GTRQMCGDPYQQ-------------------------------
MAK_a_Smoe       RRPTAYQLRQHPFFYQFGLCIPPPIE----------------------------------
GK041_Glam       KRLSAQDCLRHPWFVN-TCPTTAAASASS-------------------------------
GK039_Glam       DRITAQRALMHQFFA---------------------------------------------
                  * ..       ::

M04C9.5_Cele     ------------------------------------------------------------
DDB0229430_Ddis  -------------------------------------------------KPNFIE-----
MAK_Hsap         ---QLQPLE---------------------------------------SKPSLVE-----
ICK_Hsap         ---AGPPPY---------------------------------------IKPV--------
CG4588_Dmel      N--NVLPVQEKLQAVTELLHQTNNNMNSHSNLGKNNNLAPKNGGVPRKYQPKLSFLTTSE
ICK_Mmus         ---TGPPPY---------------------------------------IKPA--------
MAK_Mmus         ---QLQPLE---------------------------------------PKPSSSE-----
IME2_Scer        ---GINPV----------------------------------------------------
MAK_Spur         ---QAPNQN---------------------------------------SAKRRVL-----
CC1G_11298_Ccin  TPRNVPPSH---------------------------------------SNSA-HH-----
AqueK132_Aque    ---T--PNR---------------------------------------EKER--------
MAK_d_Smoe       ------------------------------------------------IK----------
MAK_c_Smoe       ------------------------------------------------IK----------
MAK_e_Smoe       -------------------------------------------------RPYVIT-----
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       -------------------------------------------------RPYVIT-----
GK041_Glam       ------------------------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ----------------------AASV---------------KS----DTKAMTA------
DDB0229430_Ddis  -----------------LSNKYLIKN---------------GYINNNINNNSN-YSNNNN
MAK_Hsap         -----------------VEPKPLPDI---------------IDQVVGQPQPKT-S-----
ICK_Hsap         ------------------PPAQPPAK---------------PHTRISSRQHQA-S-----
CG4588_Dmel      MGAGSHADSSSLVGGATVDGVPVPQHQNGGESINDIYLNRNISQLFGLPAGP-QH-----
ICK_Mmus         ------------------PPAQAPAK---------------AYTLISSRPSQA-S-----
MAK_Mmus         -----------------RDPKPLPNI---------------LDQPAGQPQPKQ-G-----
IME2_Scer        -----------------------A-----------------------------TN-----
MAK_Spur         -----------------AESKPAPSP---------------LS----KVQPKRDN-----
CC1G_11298_Ccin  -----------------VRPPPVPSH---------------FPE---VPPP--QN-----
AqueK132_Aque    ------------------ENERGSRW---------------QE----DKEGKR-A-----
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       -----------------IDPDEQADY---------------NYYRRGQIHNTG-Y-----
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       -----------------IDPDEQADY---------------NYYRRGQIHNTG-Y-----
GK041_Glam       ------------------------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     KAAK------------------------K------------D--------Y-------IG
DDB0229430_Ddis  NNNL------------------------NSNS---------E--------N---LNNVNK
MAK_Hsap         QQPL------------------------QPI---------QP--------P---QN-LSV
ICK_Hsap         QPPL------------------------HLT---------YP--------Y---KAEVSR
CG4588_Dmel      QQQQ------------------------QVH---------HP--------NVSFSTTSSR
ICK_Mmus         QPPQ------------------------HSV---------HP--------Y---KGDVSR
MAK_Mmus         HQPL------------------------QTI---------QP--------P---QN-TVT
IME2_Scer        TKPI----------------------YFNSSTK-------LPAET---ESN---DIDISN
MAK_Spur         AQPK------------------------DSM---------DD--------F---FANLGK
CC1G_11298_Ccin  SQPTPLPSVPHQPIPLHAQNGRRPHPIVGWTGPSPQPASDYPMDTSPSEPY---ANGHAN
AqueK132_Aque    NQYL------------------------GGA---------GP--------Y---DRNVSG
MAK_d_Smoe       -----------------------------------------P------------------
MAK_c_Smoe       -----------------------------------------P------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       -------------------------SFVGTTGVGGDDA----------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ------------------------------SENV-----SPQQPA---K--V-IDRHIN-
DDB0229430_Ddis  NN----------------------------QQ--------PHSPQ---KIQT-PKPKNS-
MAK_Hsap         QQP---------------------------PKQQ-----SQEKPP---Q--T-LFPSIVK
ICK_Hsap         TDH---------------------------PSHL-----QEDKPS---P--L-LFPSLHN
CG4588_Dmel      NAGAIYVNGSHLSYDTANMNAKNNAKFVVGASNG-----GYYVPVA-RP--SLLGPDAKV
ICK_Mmus         TEQ---------------------------LSHV-----QEGKPS---P--P-FFPSLHN
MAK_Mmus         HPP---------------------------PKQQ-----GHQKPP---Q--T-MFPSIIK
IME2_Scer        NDH---------------------------DSHAMCSPTLNQ----EKL--T-L------
MAK_Spur         ------------------------------SKDV-----EPSKPV---Q--E-KAPNAG-
CC1G_11298_Ccin  NGH---------------------------SEHHP--PAGHSMPPPKSL--K-LGPFGKK
AqueK132_Aque    TKK------------------------------F-----EQAKAE---K--G-GLPEVLK
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------SQ-----------PL---QELS-LFPSGK-
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------SQ-----------PL---QELS-LFPSGK-
GK041_Glam       --------------------------------------------S---------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     -------------------------R-------N--------------------------
DDB0229430_Ddis  ------------------------------------------------------------
MAK_Hsap         -N---MPTKPNGTL---------SHK-------SGRRRWGQTIF--KSGD--S----WEE
ICK_Hsap         KH---PQSKITAGL---------EHKNGEI-KPKSRRRWGLISRSTKDSD--D----WAD
CG4588_Dmel      YN---VFSKVSASQAPPSLIVRQPQLQPEV-APAPMRLSG-RSRAAAAVQ--DPKMGALK
ICK_Mmus         KN---LQPKILASL---------EQKNGEI-KPKSRRRWGLISRSTKGSD--D----WAD
MAK_Mmus         -T---IPVNSVSTL---------GHK-------GARRRWGQTVF--KSGD--S----CDD
IME2_Scer        ------------------------------------VE-FLNEFVEEDNDDHS----IPD
MAK_Spur         ------------------------NK-------SGRRKWET-GK--KVED--S----WDD
CC1G_11298_Ccin  S-----------------------------------SRWALGIFGSEKS--HQ----LPP
AqueK132_Aque    KSSGSYNNSPLFGS---------HNANGGIVTQHQRKQWQT-RSTAESGD--S----GVD
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       ------------------------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ------------------------------------------LP-------------LNK
DDB0229430_Ddis  ------------------------------------------------------------
MAK_Hsap         LE--DY-DFGASHSKKPSMGVF----------------KEK----------------RKK
ICK_Hsap         LD--DL-DFSPSLSRI-DLK-N----------------KKR----------------QSD
CG4588_Dmel      SD--DL-DLILGSK--LKTSAK----------------RQR-----------------NA
ICK_Mmus         LD--DL-DFSPSLTRI-DVK-N----------------KKR----------------QSD
MAK_Mmus         IE--D--DLGASHSKKPSMEAC----------------KEK-----------------KK
IME2_Scer        VG-TDS-TISDSIDET-ELS------------------KEI----------------RNN
MAK_Spur         FDLEGSRGFGGTSAKTKKIGGM----------------KGKALPTI-----GAGNA-VGK
CC1G_11298_Ccin  VD--EV-T------TT-ALG------------------TRK----------------RSQ
AqueK132_Aque    SE--GA-QFSNHFNSFPKYKGPPLKPPAPVITSLVPPSKPSAVPLISSLFGGQKRAVKRK
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       ------------------------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ETLFEKSD---------NKPLGP---TK--------------------------------
DDB0229430_Ddis  ------------------------------------------------------------
MAK_Hsap         DSPFRLPEP---VPSGSNHSTGE---NKSL----------PA--VTSL------------
ICK_Hsap         DTLCRFESV---LDLKPSEPVGT---GNSA----------PT--QTSY------------
CG4588_Dmel      KANILLEDL---FGQLSMDSDSDGKYPHTV----------PPTQQAKS------------
ICK_Mmus         DTLCRFESV---LDLKPSESVGT---GTTV----------ST--QASS------------
MAK_Mmus         ESPFRFPDS---GLPVSNHFKGE---NRNL----------HA--SVSL------------
IME2_Scer        LALCQLPDE-EVLDHSLSNIRQ----------LTNDIEIINK--DEAD------------
MAK_Spur         KASLDWEDDDDFLKSPTKHRVGPLS-TRNQ----------PG--VARV------------
CC1G_11298_Ccin  SSSTDG--K-SVRDLSPERPQDL---REVQKQQKKEAERINR--EAEK------------
AqueK132_Aque    DTLPTI---DSFVGGDDQSRRGQ-----FV----------AK--ETTGGRRDEGLDKFPF
MAK_d_Smoe       --LCRWVR----------------------------------------------------
MAK_c_Smoe       --LCRWVR----------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       -----------TEGLSV-----------------------AR------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ------------SNEAKPTAKEIYLSKSK-----YV--PGTV-KNKFKK-----------
DDB0229430_Ddis  -----------------------FLRKSR-----YSYLNNVSLENVNNNNNNYNSNTTSG
MAK_Hsap         ------KSD--SELSTAPTSKQYYLKQSR-----YL--PGVNPKKVSLI-----------
ICK_Hsap         ------QRR--DTPTLRSAAKQHYLKHSR-----YL--PGISIRNGILS-----------
CG4588_Dmel      ------GKT--STGGHGAGARERDLFGES-----YL--PRPGLRKKATQ-----------
ICK_Mmus         ------QRR--DTPTLQSSAKQHYLKHSR-----YL--PGINIRNGVLP-----------
MAK_Mmus         ------KSD--PNLSTASTAKQYYLKQSR-----YL--PGVNPKNVSLV-----------
IME2_Scer        ------NMEQLFFDLEIPE-KDEFQRKQPFNE---------------HA-----------
MAK_Spur         ------GLE--SGKSSASSAKQFYMGKAR-----YL--PGMNVKSPRKD-----------
CC1G_11298_Ccin  ------ERRKLAEKMAREQARAVMSKRNRMLREAVG--EDI---DWSGG-----------
AqueK132_Aque    SWKSKVHVS--PGVVDKREASNFYLTRAR-----YS--PIVSGKVGF-G-----------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       ---------------------------NALQRATRA--TDL---NL--------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ------------------------------------------------------------
DDB0229430_Ddis  YYNQKLDSTPRLSPRIVRQQQQQILLPLIIQQQPPPQSQPPQSQPPPQSQPPPILTQQQQ
MAK_Hsap         ------------------------------------------------------------
ICK_Hsap         ------------------------------------------------------------
CG4588_Dmel      ------------------------------------------------------------
ICK_Mmus         ------------------------------------------------------------
MAK_Mmus         ------------------------------------------------------------
IME2_Scer        ------------------------------------------------------------
MAK_Spur         ------------------------------------------------------------
CC1G_11298_Ccin  ------------------------------------------------------------
AqueK132_Aque    ------------------------------------------------------------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ----------------LRN-----------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ----------------LRN-----------------------------------------
GK041_Glam       ------------------------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ------------------S-L---KWLDLLI--------PYLNCQVSKDTH-QNQIMT--
DDB0229430_Ddis  QQQQQQQQQQQLPSKTTIY-----HNT-NHL--------NAPIP----------------
MAK_Hsap         ------------------A-----SGK-EI---------NPHTWSNQ-LFP-KSLGPVGA
ICK_Hsap         ------------------N-----PGK-EFI--------PPNPWSSSGLSG-KSSGTM--
CG4588_Dmel      ------------------SSLEVNNGS-H-A--------DSLWWQVQGFGFISPTGEVYM
ICK_Mmus         ------------------N-----PGK-DFL--------PSNSWSSSGLSG-KSSGTV--
MAK_Mmus         ------------------A-----GGK-DI---------NSHSWNNQ-LFP-KSLGSMGA
IME2_Scer        ------------------D-----IDEDIVL--------PYVNNSNYTHTD-RSHH----
MAK_Spur         ------------------S--------GHGL--------PALNKVPSGSAH-RSNILG--
CC1G_11298_Ccin  ------------------N-----QERVVDKGTKQASSGPIRQKS---------------
AqueK132_Aque    ------------------S-----GAP-RFN--------D-PT-----------------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------QQHSSLASKAFSY-----GFP-DVI--------PCIKR----------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------QQHSSLASKAFSY-----GFP-DVI--------PCIKR----------------
GK041_Glam       --------------------------------------------D---------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     -----------------T-------------------------------NGLTG------
DDB0229430_Ddis  ---------------------PN--------------------------HQRGI------
MAK_Hsap         ELAFK------RSNAEESIIKPI-EKLSCNETFPEKLEDPQG-NLGSYATYNQS------
ICK_Hsap         -----------------SVISKV-NSV--------------G-SSSTSSSGLTG------
CG4588_Dmel      VYGLHKAWVSERGIRFLSYHKLVTATM--------------G-QDSSYKSGLSQ------
ICK_Mmus         -----------------SVVSKI-TSV--------------G-SGSASSSGLTG------
MAK_Mmus         DLSFK------RSNAEDSIIKPI-ENLSCTGKSAEQLEDPQG-NLGSYTTYNQT------
IME2_Scer        -----------------------------------RG---DN-VLGDASLGDSF------
MAK_Spur         -----------------SNYA-------------RRTENNYG-N--GGGNGGGG------
CC1G_11298_Ccin  ----------------------------------------MG-NLGNSTLHAASGKYSEP
AqueK132_Aque    ----------------------------PSPKHSGSIREPNGRNLLPYGQYGEG------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ---------------------PV-AGLGISSKHVCSGED----LSLSTASGGGR------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ---------------------PV-AGLGISSKHVCSGED----LSLSTASGGGR------
GK041_Glam       ----------------------------------------LL-NGGN--PYAHG------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     --------------------------------------------T---------------
DDB0229430_Ddis  ------------------------------------------------------------
MAK_Hsap         ------------------------------------------------------------
ICK_Hsap         ------------------------------------------------------------
CG4588_Dmel      --------------------------------------------A---------------
ICK_Mmus         ------------------------------------------------------------
MAK_Mmus         ------------------------------------------------------------
IME2_Scer        ------------------------------------------------------------
MAK_Spur         ------------------------------------------------------------
CC1G_11298_Ccin  PAPPVSFDRYRDWRGTGERVAKARRREYDDDHSMSSSDVHSLSRVSSISFATVDSDPGPS
AqueK132_Aque    ------------------------------------------------------------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       ------------------------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     --------------------------TKTTTFSAK-------------KEGRTA------
DDB0229430_Ddis  --------------------------SP--QF----------------------------
MAK_Hsap         --------------------------GYIPSFLKK-------------EVQSAG------
ICK_Hsap         --------------------------NYVPSFLKK-------------EIGSAM------
CG4588_Dmel      -----------LTHQSSALHRF----SYNSNLFAM-------------NVLAGI------
ICK_Mmus         --------------------------SYIPSFLKK-------------EIGSVM------
MAK_Mmus         --------------------------GYMPSFLKK-------------EVGSAG------
IME2_Scer        --------------------------NSMPDFTPR-------------NFLI--------
MAK_Spur         --------------------------NYMPSFSTK-------------QDSSAR------
CC1G_11298_Ccin  RLRHHSSFHHAASSRTSRSSLRTSFDDFSPSARSSNSFSLEGSSSLAHEFGAHLNVNPHI
AqueK132_Aque    --------------------------GRGRQWNGG-------------GE----------
MAK_d_Smoe       --------------------------VYHPRFR---------------------------
MAK_c_Smoe       --------------------------VYHPRFR---------------------------
MAK_e_Smoe       --------------------------NPMLQF----------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       --------------------------NPMLQF----------------------------
GK041_Glam       --------------------------DILPSYAQK-------------KAKTTK------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ---------V-----------------------------QTR------------------
DDB0229430_Ddis  ------------------------------------------------------------
MAK_Hsap         ---------QRIHLAP----------------------LNATASEYTWN-----------
ICK_Hsap         ---------QRVHLAP----------------------IPDPSPGYS-S-----------
CG4588_Dmel      ---------IASHPDE----------------------LIASPAQYEFHYSVHDSHSGDV
ICK_Mmus         ---------QRVQLAP----------------------LAAPPPGYS-S-----------
MAK_Mmus         ---------QRIQLAP----------------------LGASASDYTWS-----------
IME2_Scer        ---------------P--------------------------------T-----------
MAK_Spur         ---------IGGYNEP----------------------WKTT------------------
CC1G_11298_Ccin  SGSVSPPPLHMLSLSPTLSPPLSPNPPWIQVQDIKENGLGGQSPPYI-T-----------
AqueK132_Aque    ------------------------------------------------------------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       ---------ELIEL----------------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ---FEYA----YGSSFCS---SHK-SLF--------------------------------
DDB0229430_Ddis  ------------------------------------------------------------
MAK_Hsap         ---TKTGRGQFSGRTYNPTA--KN-LNIVN------------------------------
ICK_Hsap         ---LKAMRP-HPGRPFFHTQPRST-PGLIP------------------------------
CG4588_Dmel      KDQFEHRRGEYVTGRYSLVDPDGH-RRIVD------------------Y-----------
ICK_Mmus         ---LKAVRP-HPGRPFFHTQPRST-PGLIP------------------------------
MAK_Mmus         ---TKTGRGQFSGRTYNPTA--KN-LNIVN------------------------------
IME2_Scer        ---LKKSR-----EKFEPHL--S-------------------------------------
MAK_Spur         ---TKAG----VTNTFGA---ARN-NGL--------------------------------
CC1G_11298_Ccin  ---LQN-------RQFSPSP--HSPLDIHN------------------YLQQPPSPFNNP
AqueK132_Aque    ---ARAG-----GGAFFGNRTRGV-ENVTTTTAAAAAASNNHRGGGGGG-----------
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ------------------------------------------------------------
MAK_b_Smoe       ------------------------------------------------------------
MAK_a_Smoe       ------------------------------------------------------------
GK041_Glam       --------------DHNDEL--HD------------------------------------
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ---LF-VF-LLPF----------------------------------------------G
DDB0229430_Ddis  ----------------------------------------------------------YN
MAK_Hsap         RAQPIPSVHGRTD----------------------------------------------W
ICK_Hsap         RPPAAQPVHGRTD----------------------------------------------W
CG4588_Dmel      TADPLLGFNA--Q----------------------------------------------V
ICK_Mmus         RPPAAQPVHGRID----------------------------------------------W
MAK_Mmus         RTQPVPSVHGRTD----------------------------------------------W
IME2_Scer        ---------------------------------------------------------NSN
MAK_Spur         ---RAQPVHGRTD----------------------------------------------W
CC1G_11298_Ccin  SAPAQPPTTGQTPRSANSAINPIFKVVSLDPDVMLFYRCLTYSTALTSPSTTFITAPCRP
AqueK132_Aque    SVLPNLGLLARVD----------------------------------------------W
MAK_d_Smoe       ------------------------------------------------------------
MAK_c_Smoe       ------------------------------------------------------------
MAK_e_Smoe       ---------GEND--------------------------------------------YLA
MAK_b_Smoe       ---------------------------------------------------------LTC
MAK_a_Smoe       ---------GEND--------------------------------------------YLA
GK041_Glam       ---------------------------------------------------------NNM
GK039_Glam       ------------------------------------------------------------


M04C9.5_Cele     ACLSSQYS
DDB0229430_Ddis  ETTNNSKL
MAK_Hsap         VAKYGGHR
ICK_Hsap         ASKYASRR
CG4588_Dmel      RREPISRY
ICK_Mmus         SSKYPSRR
MAK_Mmus         VAKYGGHR
IME2_Scer        QHFGNVTF
MAK_Spur         ASKYGGVR
CC1G_11298_Ccin  TSEFYIPD
AqueK132_Aque    SSR--YKR
MAK_d_Smoe       SRNFVKTK
MAK_c_Smoe       SRNFVKTK
MAK_e_Smoe       LQVYQGYP
MAK_b_Smoe       KMATQCVI
MAK_a_Smoe       LQVYQGYP
GK041_Glam       LDMIDDMF
GK039_Glam       -------I