MAP3K1_Mmus     WLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLN
MAP3K1_Hsap     WLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLN
MEKK1_Spur      WTKGAILGTGAFSSCYMARDVKTGTLMAVKQISFCRNNAGDQEDTMEEIKKEIKLMATFD
AqueK225_Aque   -----------------------------KQIRLEQESLTAVNETLISLRLSS---SSKD
                                             **:   ::.    ::.:  :: .    .  :

MAP3K1_Mmus     H-PNIIRMLGATC----EKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGL
MAP3K1_Hsap     H-PNIIRMLGATC----EKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGL
MEKK1_Spur      H-PHIVRLMGATQ----HDAHFNVFVEWMPGGAVSTLLKDFGAFSNAVTVKYIHQVCLGL
AqueK225_Aque   HPPNIVEFYGASLLPLQVETKLQLFLELMPCCLQ-SYLYNGGPLSVEDAHNYACQLFDAL
                * *:*:.: **:      .:: ::*:* *.       * . *.:.   . :*  *:  .*

MAP3K1_Mmus     SYLHEN-QIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFM
MAP3K1_Hsap     SYLHEN-QIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFM
MEKK1_Spur      AYLHDN-RVIHRDLKGANLLMDSTGHHLRIADLGTAGKMNADITRTDEFKGQFLGTISFM
AqueK225_Aque   DYLHGKINLVHSDIKPGNLLIDENVQRLKVTDFGCSQVLEDSHQGYCMRGDANAGTVHYN
                 *** : .::* *:* .***:*.. ::*:::*:* :  :  .        .   **: :

MAP3K1_Mmus     APEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAE------------KHSNHLALIFKI
MAP3K1_Hsap     APEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAE------------KHSNHLALIFKI
MEKK1_Spur      APEVLRGEPYGRSCDIWSVGCCIIEMCTTKPPWNNT------------AISNHYQLLFKI
AqueK225_Aque   PPEHYSEFRCSYALDIWQAGCCIIAMVTGRRPWRSMYLDCRERRYRAEVQQSQIQQ---I
                .**       . : *:*..**.** *   : **.                ..:      *

MAP3K1_Mmus     ASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVF
MAP3K1_Hsap     ASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVF
MEKK1_Spur      ASANGPPPIPESLSPALRDITLRCLEAEPSARPGVMELLKHPAF
AqueK225_Aque   CKVPYSHHVPGFLDPALQQLVQQCLSIDYRRRPSLKDCLG--LL
                ...  .  :*  *.*.*:::. :**. :   **   : *    :