PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin KRPQSRGKEKALSFLKFGKRSPKSPPTKDASWDSAVPPLPSNGDDGISTPFNFQHNIHVN
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin EGLVGLPPTWSAALSQAGFSDEEIIAIHNRRAAGSRSPNSQYVLNARPPSPRIPHPYQQS
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin ASNVPIIAQPGPRTTSLPRQVSDASLRSTSTRQRHPIPFGSPASASTASLHSSNAGSISN
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin IKAVRQGASQDHSSRNHTPQLSISYSSDSNHSGVSGEDVYQQSRNGNFPKDVSTPPGKPA
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin HAANPSIAQSFMSQASSLLNGHSHNRNESNASSTSKRLFGSQPSLWSSPSSSSTASRPQT
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin AANTSTSSNHSNAAVTQPTDNNASPEASPPQPKRTNALPPRLSLHQASGSGDLSAWAGML
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin LSGLSSDLDDKLTLGPSPLGPTPLTPQSAPASAATQGPSSFTVSNRPTHTSHSRSLGGES
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin SKARPEPLSELEEPIDNDAQYANLSPPWTGDAGSSSPLWSEIEGILSQGRSPTASEDRHE
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin PGPYSAALAETFSPTLPFSPEEDRMAQERRLRNEASRERLEREEDLNRLSVNTARPNRDS
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin SRSIPPTPIVPPPRQLPNRPAPIDAGHSPSPPNSSFDSEESSASSSQSQDRYPTPTTANS
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin TSSPLRYYLEPSPSPSQASFSPVVARHKEYPNVPPAYDIDEDLDEDDEEGTNLIIPHQII
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ------------------------------------------------------------
PAK2_Hsap ------------------------------------------------------------
PAK1_Hsap ------------------------------------------------------------
PAK3_Mmus ------------------------------------------------------------
PAK2_Mmus ------------------------------------------------------------
PAK1_Mmus ------------------------------------------------------------
pak-1_Cele ------------------------------------------------------------
STE20_Scer ------------------------------------------------------------
SKM1_Scer ------------------------------------------------------------
CLA4_Scer ------------------------------------------------------------
Pak3_Dmel ------------------------------------------------------------
Pak_Dmel ------------------------------------------------------------
Y38F1A.10_Cele ------------------------------------------------------------
PakA_Ddis ------------------------------------------------------------
PakB_Ddis ------------------------------------------------------------
PakC_Ddis ------------------------------------------------------------
PakD_Ddis ------------------------------------------------------------
19075_Tthe ------------------------------------------------------------
25909_Tthe ------------------------------------------------------------
PAK1_Spur ------------------------------------------------------------
CC1G_15304_Ccin TAPSPQANRPTIVIENVSPGGALSTALPTGTPASPFQRYRGWLSEVVQPLEEYIDEGVDP
CC1G_00840_Ccin ------------------------------------------------------------
CC1G_02087_Ccin ------------------------------------------------------------
AqueK235_Aque ------------------------------------------------------------
GK081_Glam ------------------------------------------------------------
PAK3_Hsap ---YTRFEKIGQGASGTVYTALDI---------------------AT-GQ--EVAIKQMN
PAK2_Hsap ---YTRYEKIGQGASGTVFTATDV---------------------AL-GQ--EVAIKQIN
PAK1_Hsap ---YTRFEKIGQGASGTVYTAMDV---------------------AT-GQ--EVAIKQMN
PAK3_Mmus ---YTRFEKIGQGASGTVYTALDI---------------------AT-GQ--EVAIKQMN
PAK2_Mmus ---YTRYEKIGQGASGTVFTATDV---------------------AL-GQ--EVAIKQIN
PAK1_Mmus ---YTRFEKIGQGASGTVYTAMDV---------------------AT-GQ--EVAIKQMN
pak-1_Cele ---YRKVDKIGSGASGSVYTAIEI---------------------ST-EA--EVAIKQMN
STE20_Scer ---YANLVKIGQGASGGVYTAYEI---------------------GT-NV--SVAIKQMN
SKM1_Scer ---FQLVEKAGQGASGAVYLSKRIKLPQEN-DPRF-LK-SHCHR-VV-GE--RVAIKQIR
CLA4_Scer ---FKVIEKAGQGASGSVYLAERTHIPTES-NMIELINNDIDEP-HV-GD--KVAIKQMV
Pak3_Dmel ---YKTTQEVGKGASGIVFIAADL---------------------QN-ES--QVAVKTID
Pak_Dmel ---YTKMEKIGQGASGTVYTAIES---------------------ST-GM--EVAIKQMN
Y38F1A.10_Cele ---YEMKKQIGVGASGTVFVANVA---------------------GS-TD--VVAVKRMA
PakA_Ddis ---YYNINKIGEGGAGEVFEAINS---------------------RT-NQ--TIAIKKMK
PakB_Ddis --------KIGEGAAGEVFVVTQL---------------------KT-NN--KVAIKKMP
PakC_Ddis ---YKNMTKIGEGAAGEVFVATSS---------------------KN-NK--RVAIKKIE
PakD_Ddis ---YKVREVVGGGSTGKVYVGENS---------------------IT-GE--KVAIKKMK
19075_Tthe ---YDFLSQIGKGATCKVYRCKNK---------------------QT-GQ--ECAMRVIR
25909_Tthe ---YNFGDKLGKGAMCQVFKATKR---------------------KTKNE--EFAVRVMK
PAK1_Spur ---YSKFEKIGQGASGVVYTAIEV---------------------AT-GQ--EVAIKQMN
CC1G_15304_Ccin RDHYLDLKEIAEGESGSVFSARLIQKDADKLRLPAHVKAQDADDFAN-NREVLVAIKSVA
CC1G_00840_Ccin ---YRNLVKIGQGASGGVYTAYQV---------------------GT-NM--SVAIKQMD
CC1G_02087_Ccin ---YSKIKKVGQGASGHVYVAKEL---------------------AT-GK--KVAIKEMD
AqueK235_Aque ---YTKMEKIGQGASGVVYTASEI---------------------AT-GN--EVAIKQMN
GK081_Glam ---YSNPQEVGHGSSGHVYRATEIK---------------------T-GN--VVAIKSIS
. * *: *:: :
PAK3_Hsap L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
PAK2_Hsap L----------------QKQPKKELIINEILVMKELKN-PNIVNFLDSYLVG--DELFVV
PAK1_Hsap L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
PAK3_Mmus L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
PAK2_Mmus L----------------QKQPKKELIINEILVMKELKN-PNIVNFLDSYLVG--DELFVV
PAK1_Mmus L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
pak-1_Cele L----------------KDQPKKELIINEILVMRENKH-ANIVNYLDSYLVC--DELWVV
STE20_Scer L----------------EKQPKKELIINEILVMKGSKH-PNIVNFIDSYVLK--GDLWVI
SKM1_Scer L----------------SEQPKKQLIMNELLVMNDSRQ-ENIVNFLEAYIID-DEELWVI
CLA4_Scer L----------------SKQPRKELIVNEILVMKDSRH-KNIVNFLEAYLRT-DDDLWVV
Pak3_Dmel M----------------KNQSSKDLILTEIRVLKDFNH-KNLVNFLDAYLLEPEDQLWVV
Pak_Dmel L----------------SQQPKKELIINEILVMRENKH-PNVVNYLDSYLVS--EELWVV
Y38F1A.10_Cele F----------------KTQPKKEMLLTEIKVMKQYRH-PNLVNYIESYLVD-ADDLWVV
PakA_Ddis L----------------KAQNLK-TVINEIGMMKNSNH-ENIVQYIDSYIVA-D-ELWVA
PakB_Ddis L----------------NQQNMK-LIVTEIGIMKSCRH-QNIIDYIDSYLVG-D-SLWVA
PakC_Ddis I----------------NNDNAK-LLVTEIAIMKTSHH-DNIVNYIDSYIVN-DRELWVA
PakD_Ddis V----------------DNNNIK-NIINEISTMKNSKH-KNVIKYVSSHLVI-N-HIWLI
19075_Tthe M----------------LNPDQIEKTKMEILLMNESKN-NNIVQYYKSYIYM--DVIFMA
25909_Tthe L----------------GDEGSMNKIKIEMAIMKICQH-KNIVRYYETFKFM--SCLFMV
PAK1_Spur L----------------QQQPKKELIINEILVMRENKH-QNIVNYLDSYLVS--DELWVV
CC1G_15304_Ccin IV--------------PSGSPKLKDLQHELGLMKGLHH-ENVIGLDSLYVDFLEDTLWIR
CC1G_00840_Ccin L----------------DKQPKKDLIINEILVMRSSRH-PNIVNYIDSFLYK--NDLWVV
CC1G_02087_Ccin L----------------SHQPRKELIVNEILVMKESQH-PNIVNFLNSYLVK-NNELWVV
AqueK235_Aque L----------------QQQPKKELIINEIIVMKEIKQ-PNIVNFLDSYLVG-ESELWVV
GK081_Glam AINFLTDDGKKVRDIKSAEAATLMALKNEVALMYLSKECEYIVKLHKVYFSKAAKEFYMI
*: : .. :: . . :::
PAK3_Hsap MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALDFLHS
PAK2_Hsap MEYLAGGSLTDVVTE---------------------TCMDEAQIAAVCRECLQALEFLHA
PAK1_Hsap MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALEFLHS
PAK3_Mmus MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALDFLHS
PAK2_Mmus MEYLAGGSLTDVVTE---------------------TCMDEAQIAAVCRECLQALEFLHA
PAK1_Mmus MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALEFLHS
pak-1_Cele MEYLAGGSLTDVVTE---------------------CQMEDGIIAAVCREVLQALEFLHS
STE20_Scer MEYMEGGSLTDVVTH---------------------CILTEGQIGAVCRETLSGLEFLHS
SKM1_Scer MEYMEGGCLTDILDAVARSN----T-------GEHSSPLNENQMAYIVKETCQGLKFLHN
CLA4_Scer MEFMEGGSLTDIIENSPTND-------------NSHSPLTEPQIAYIVRETCQGLKFLHD
Pak3_Dmel MEYMDGGPLTDVVTE---------------------TVMKERQIACVCRETLYAISFLHA
Pak_Dmel MEYLPGGSLTDVVTE---------------------TCMDEGQIAAVCREVLQALEFLHA
Y38F1A.10_Cele MDYLEGGNLTDVVVK---------------------TELDEGQIAAVLQECLKALHFLHR
PakA_Ddis MEFMSGGCLTEVLDQYR------------------DIQLNESQIAFVCQEVLRGLEYIHK
PakB_Ddis MEFMGGGCLTEILEQFN------------------SVKLVEAQIAYVCAETLKGLAYIHS
PakC_Ddis MEFMGGGCLTDILEAFD------------------NIKMSEIQIAYVVKETLKALQYIHS
PakD_Ddis MEYMSYGSLTDLISNCINIQCNGNNQQQQQQQQQQQTYFIESHIAYICQQVLQGMDYIHK
19075_Tthe IEYMNAGSLTELIYGN-------------------FSFLSEQMASYICEQILFGLFFIHR
25909_Tthe IEYMNGGSLTEIIYQN-------------------FKTIPEDIIAYILREIIQGLNFIHL
PAK1_Spur MEFLAGGSLTDVVTE---------------------TCMDEGQIASVCRECLQALQFLHQ
CC1G_15304_Ccin MELME-RSLADIIGLVD-----------------AGLMLPDRMMARFASDILSGLDYLQR
CC1G_00840_Ccin MEYMEGGSLTDVVTA---------------------NLMTEGQIAAVSRETCQGLEHLHR
CC1G_02087_Ccin MEYMEGGALTDVIEN---------------------NTLEEDQISSICLETCKGLQHLHS
AqueK235_Aque MEYLAGGSLTDVVTE---------------------TCMNEGQIAAVCRECLQALKFLHD
GK081_Glam MDYCNANCLTNILSRH-------------------GYIKNERVSCMIIRDILKALNHLHE
:: *:::: : . : .: .::
PAK3_Hsap NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK2_Hsap NQVIHRDIKSDNVLLGME----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK1_Hsap NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK3_Mmus NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK2_Mmus NQVIHRDIKSDNVLLGME----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK1_Mmus NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
pak-1_Cele RHVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQLSPEQRKRTTMVG
STE20_Scer KGVLHRDIKSDNILLSME----------------GDIKLTDFGFCAQINELNLKRTTMVG
SKM1_Scer KKIIHRDIKSDNILLNSQ----------------GLVKITDFGFCVELTEKRSKRATMVG
CLA4_Scer KHIIHRDIKSDNVLLDTR----------------ARVKITDFGFCARLTDKRSKRATMVG
Pak3_Dmel KGIIHRDIKSDNVLLGMD----------------GSVKVTDFGFCANIEG-DEKRQTMVG
Pak_Dmel NQVIHRDIKSDNILLGLD----------------GSVKLTDFGFCAQISPEQSKRTTMVG
Y38F1A.10_Cele HSIVHRDIKSDNVLLGMN----------------GEVKLTDMGFCAQIQP-GSKRDTVVG
PakA_Ddis FNRIHRDIKSDNILIGAN----------------GEIKLADFGYAAQLTQIRQERNSVVG
PakB_Ddis QHRIHRDIKSDNILLGSD----------------GSVKLADFGYAAQLTKSKQKRVTIVG
PakC_Ddis LHRIHRDIKSDNILLGSE----------------GSVKIADFGYAAQLTQKQQKRNTVVG
PakD_Ddis GHRTHRDIKSDNILLGKD----------------GSVKIADFGFVANLTRKKLQRNSVVG
19075_Tthe TNQIHRDLKSDNILLNQN----------------GDVKIADFGFATQLTREHFSKKSQVG
25909_Tthe QNQAHRDLKSDNILVNKN----------------GEVKVADFGFATQLTQEKQRRKSVVG
PAK1_Spur RHVIHRDIKSDNILLGMD----------------GNVKLTDFGFCAQITPEQSKRTTMVG
CC1G_15304_Ccin HHIAHRDVRSDNLLINKH----------------GVLKLTDFANAVQVSAQNPMRTEPAG
CC1G_00840_Ccin HGVIHRDIKSDNVLLSMV----------------GDIKLTDFGFCAQISEGHAKRTTMVG
CC1G_02087_Ccin QSIIHRDIKSDNVLLDAQ----------------GRVKITDFGFCAKLTDQKSKRATMVG
AqueK235_Aque NHVIHRDIKSDNILLGMD----------------GQVKLTDFGFCAQITPEQSKRSTMVG
GK081_Glam NHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKLSDFGFAVQLNTKQPTRKSVVG
:**::***:*:. :*::*:. ..: : .*
PAK3_Hsap TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK2_Hsap TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK1_Hsap TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN
PAK3_Mmus TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK2_Mmus TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK1_Mmus TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN
pak-1_Cele TPYWMAPEVVTRKQYGPKVDVWSLGIMAIEMVEGEPPYLNENPLRAIYLIATNGKPDFPG
STE20_Scer TPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKE
SKM1_Scer TPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRH
CLA4_Scer TPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKH
Pak3_Dmel TPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKS
Pak_Dmel TPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKE
Y38F1A.10_Cele TPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQNGKPEIKQ
PakA_Ddis TPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGEPPYLEFPPLRALFLLTTQGLPPIRD
PakB_Ddis TPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLITTKGIPDLKD
PakC_Ddis TPYWMAPELIRGHDYGVKVDIWSLGIMMMEMAEGEPPYMDFPPLRALFLITTKGIPPLKE
PakD_Ddis TPYFMAPELIRGNQYNHKVDIWSLGILARELSEGEPPYAKYPPVRALFLLTLEGVPDFKE
19075_Tthe TPAWMAPELILRKDYSQKVDIWSLGVICIEILEGEPPYIRDKPAKAMYYITKK-KPHKLD
25909_Tthe TPAWMAPELILKKEYNEKVDVWSTGIIAIELAMGEPPHLRMPPLKAMYTISSKAPPRL-D
PAK1_Spur TPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPDIHN
CC1G_15304_Ccin VLYWQAPEVRSPPYNAMKVDVWSLGATVWEMAETQPPFADTNEFG-------DRWPPLSR
CC1G_00840_Ccin TPYWMAPEVVTRKEYGPKVDIWSLGIMAIEMIEGEPPYLNQNPLKALYLIATNGTPTIAN
CC1G_02087_Ccin TPYWMAPEVVKQKEYGAKVDIWSLGIMAIEMIENEPPYLDEEPLKALYLIATNGTPTLKK
AqueK235_Aque TPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
GK081_Glam TPFWMAPELIRGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKK
. : :**: *:* ** * *: **. . *
PAK3_Hsap PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL
PAK2_Hsap PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL
PAK1_Hsap PEKLSAIFRDFLNRCLEMDVEKRGSAKELL----Q
PAK3_Mmus PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL
PAK2_Mmus PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL
PAK1_Mmus PEKLSAIFRDFLNRCLEMDVEKRGSAKELL----Q
pak-1_Cele RDSMTLLFKDFVDSALEVQVENRWSASQLLTHPFL
STE20_Scer PENLSSSLKKFLDWCLCVEPEDRASATELLHDEYI
SKM1_Scer PESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
CLA4_Scer PESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF
Pak3_Dmel WDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFL
Pak_Dmel KDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFL
Y38F1A.10_Cele RDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPFL
PakA_Ddis AHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
PakB_Ddis QNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
PakC_Ddis TTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
PakD_Ddis PNKWSSDFIEFVNLCLNLDDKRRPDAHYLLRHPFL
19075_Tthe ATKFSQEACDFVSTCLNIDPQERPTAQQLISHPFI
25909_Tthe PANFTQNFCNFVEQCLQKNPDERASFQTLLEHPFL
PAK1_Spur PDRLSPVFRNFLAKCLETDVDKRADGEMLLKHPFL
CC1G_15304_Ccin PQLVSPAFHEFLRLCSEP-AASRPTAGELLKTPFV
CC1G_00840_Ccin PENLSPVFTDYLAKTLEVDAEKRPSATELLQHPFF
CC1G_02087_Ccin PEALSKELKSFLAVCLCVDVASRATAIELLDHEFL
AqueK235_Aque PENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
GK081_Glam PSQWTPELNDFLARCLDKDPDSRWSCAQLLEHPWI
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