PKCz_Hsap MPS----------RTGP------------KMEGSGGRVRLKAHYGGDIFITSVDAATTFE
PKCi_Hsap MPT----------QRDS--STMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFE
aPKC_Dmel MPS----------QILNDGSSVSLNSASMNMANTPNSITVKTAYNGQIIITTINKNISYE
PKCz_Mmus MPS----------RTDP------------KMDRSGGRVRLKAHYGGDILITSVDAMTTFK
PKCi_Mmus MPT----------QRDS--STMSHTVACGGGGDHSHQVRVKAYYRGDIMITHFEPSISFE
pkc-3_Cele MSS----------PTSL------------EE---DGDIKLKTRFQGQVVVLYARPPLILD
PKCi_Spur MAL----------HR------------ALHIENV--------------------------
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque MHFGCGRFAAFPCSFLP--PFSAFLSRLSKMGDD--IIPVRLSFRGKDIKFSLVPNLAVT
PKCz_Hsap ELCEE------VRDMCRLHQQ--HPLTLKWVDSEGDPCTVS--SQMELEEAFRLARQCRD
PKCi_Hsap GLCNE------VRDMCSFDNE--QLFTMKWIDEEGDPCTVS--SQLELEEAFRLYELNKD
aPKC_Dmel ELCYE------IRNICRFPLD--QPFTIKWVDEENDPCTIS--TKMELDEAIRLYEMNFD
PKCz_Mmus DLCEE------VRDMCGLHQQ--HPLTLKWVDSEGDPCTVS--SQMELEEAFRLVCQGRD
PKCi_Mmus GLCSE------VRDMCSFDNE--QPFTMKWIDEEGDPCTVS--SQLELEEAFRLYELNKD
pkc-3_Cele DFFAL------LKDACKQHKK--QDITVKWIDEDGDPISID--SQMELDEAVRCLNSSQE
PKCi_Spur AVCREREIEASMHCIARRHTTATTSCSRSWSRRTNIPACTS--RHQACFSCNRCSLS--S
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque DVSNE------IRKQCGLHSA--APFNLKYLDVENDPVSVSLDRQREWDEAIRLFFYNEE
PKCz_Hsap EGLIIHVFPSTPEQPGLPCPGEDKSIY-RRGARRWRKLYRANGHLFQAKRFNRRAYCGQC
PKCi_Hsap SELLIHVFPCVPERPGMPCPGEDKSIY-RRGARRWRKLYCANGHTFQAKRFNRRAHCAIC
aPKC_Dmel SQLVIHVFPNVPQAPGLSCDGEDRSIY-RRGARRWRKLYRVNGHIFQAKRFNRRAFCAYC
PKCz_Mmus EVLIIHVFPSIPEQPGMPCPGEDKSIY-RRGARRWRKLYRANGHLFQAKRFNRGAYCGQC
PKCi_Mmus SELLIHVFPCVPERPGMPCPGEDKSIY-RRGARRWRKLYCANGHTFQAKRFNRRAHCAIC
pkc-3_Cele AELNIHVFVGKPELPGLPCQGEDKTVY-RRGARRWKKIYLYNGHRFQAKRLNRRIQCFIC
PKCi_Spur STGKWRVFPTVPVRPGLPCPGEDRNIY-RRGARRWRKLYKVNGHTFQPKRFSRRALCTYC
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque KELQLHVFEGPPPKPGELCEGEDTRVYHRRGARRWRKVRRINGHAFVAKRLQ-AAYCAKC
PKCz_Hsap SERIWGLARQGYRCINCKLLVHKRCHGLVPLT--CRKHMDSVMPSQEPPVDDK-------
PKCi_Hsap TDRIWGLGRQGYKCINCKLLVHKKCHKLVTIE--CGRHSLPQEP--VMPMDQS-------
aPKC_Dmel QDRIWGLGRQGFKCIQCKLLVHKKCHKLVQKH--CTDQPEPL--VKE-RAEESSDPIPVP
PKCz_Mmus SERIWGLSRQGYRCINCKLLVHKRCHVLVPLT--CRRHMDSVMPSQEPPVDDK-------
PKCi_Mmus TDRIWGLGRQGYKCINCKLLVHKKCHKLVTIE--CGRHSLPPEP--MMPMDQT-------
pkc-3_Cele HDYIWGIGRQGFRCVDCRLCVHKKCHRHVRTH--CGQALQGPNIIPMAPASGS---L---
PKCi_Spur ADRIWGLGRQGYKCVDCKLLVHKKCHRLVKVS--CAERQANLSTLDE-RSGSGSLP-HFG
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque RERIWGLGRQGYKCEACKMVVHKRCCYYLNKDEICAGHPPA-----KQPEESD-------
PKCz_Hsap ---NEDADLPSEE-TDG-IAYISSSRKHD--SIKDDSEDLKPVIDGMDGIKISQGLGLQD
PKCi_Hsap -------SMHSDHAQTV-IPYNPS--SHE--SLDQVGE-EKEAMNTRESGKASSSLGLQD
aPKC_Dmel LP-----PLPYEA-MSG-GAEACETHDHA--HIVAPPPP--ED--PLEPG-TQRQYSLND
PKCz_Mmus ---NDGVDLPSEE-TDG-IAYISSSRKHD--NIKDDSEDLKPVIDGVDGIKISQGLGLQD
PKCi_Mmus --------MHPDHTQTV-IPYNPS--SHE--SLDQVGE-EKEAMNTRESGKASSSLGLQD
pkc-3_Cele --KGARSNTSSSTTRSGGGIDNGAFHEHEIESPGSTSHDASRAMNGNG--SSKWAVSLND
PKCi_Spur SKPGDRSDSHHKR-SKS-GSPRHRRKNRD--STASSTPS--TAPNGNDKI-GNSPISLDD
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque -------KKPSDPF--------------------------NDFLN-I-NPVSESQISLDD
PKCz_Hsap FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP
PKCi_Hsap FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP
aPKC_Dmel FELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHP
PKCz_Mmus FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP
PKCi_Mmus FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP
pkc-3_Cele FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYP
PKCi_Spur FELLRVIGRGSYAKVLLVELKATSRVYAMKVIKKELVTDDEDIDWVQTEKHVFETASNHP
AqueK019_Aque ----------------MVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHP
AqueK020_Aque FDILKVIGRGSYAKVLMVELKQTKRIYAMKVIKKELVMDEEDIDWVQTEKHVFEQASNHP
.. . ::**:*::** :. ::********** *** **. *
PKCz_Hsap FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG
PKCi_Hsap FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG
aPKC_Dmel FLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKG
PKCz_Mmus FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERG
PKCi_Mmus FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG
pkc-3_Cele FLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRG
PKCi_Spur FLVGLHSCFQTVSRLFFVIEFVSGGDLMFHMQRQRRLPEEHARFYSSEISLALNFLHEGG
AqueK019_Aque FLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFLHEKG
AqueK020_Aque FLVGLHSCFQTESRLFFVIECVNGGDLMFHMQRHRRLPEEHARFYSAEIALALNFLHEKG
*********** ****:*** * *****:***::*:*********:.** :**::**. *
PKCz_Hsap IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFS
PKCi_Hsap IIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFS
aPKC_Dmel IIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFS
PKCz_Mmus IIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFS
PKCi_Mmus IIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFS
pkc-3_Cele IIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDEYGFS
PKCi_Spur VIYRDLKLDNVLLDADGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYDFS
AqueK019_Aque IIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDY---
AqueK020_Aque IIYRDLKLDNVLLDQDGHIKLTDYGMCKEGLRAGDTTSTFCGTPNYIAPEILRGQDYGFS
:***********:* :*************.: ** ******************::*
PKCz_Hsap VDWWALGVLMFEMMAGRSPFDII--TDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVL
PKCi_Hsap VDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVL
aPKC_Dmel VDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVL
PKCz_Mmus VDWWALGVLMFEMMAGRSPFDII--TDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVL
PKCi_Mmus VDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVL
pkc-3_Cele VDWWALGVLMFEMMAGRSPFDIVG-MQNSEENTEDYLFQIILERQIRIPRSLSVRASGIL
PKCi_Spur VDWWALGVLMFEMLAGRSPFDIVGNADHPDQNTEDYLFQVILEKPIRIPRSLSVKAASVL
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque VDWWALGVLLYEMLAGKSPFDVGG-HDMSDQSTEDYLFQVILEKTIRIPRTLSVKAAQVL
PKCz_Hsap KGFLNKDPKERLGCRP--QTGFSDIKSHAFFRS-IDWDLLEKKQALPPFQPQITDDYGLD
PKCi_Hsap KSFLNKDPKERLGCHP--QTGFADIQGHPFFRN-VDWDMMEQKQVVPPFKPNISGEFGLD
aPKC_Dmel KGFLNKNPADRLGCHR--ESAFMDIVSHPFFKN-MDWELLERKQVTPPFKPRLDSDRDLA
PKCz_Mmus KGFLNKDPKERLGCRP--QTGFSDIKSHAFFRS-IDWDLLEKKQTLPPFQPQITDDYGLD
PKCi_Mmus KSFLNKDPKERLGCHP--QTGFADIQGHPFFRN-VDWDMMEQKQVVPPFKPNISGEFGLD
pkc-3_Cele KGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLT
PKCi_Spur KGFLNKNPIERLGCHP--QTGFGDITGHPFFKT-IDWDRIESRQVTPPYKPHLQSDRDLE
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque KGFLNKSPGERLGCHL--QTGFADITNHSFYKT-IDWELLRCRQITPPYKPRIDSDRDPS
PKCz_Hsap NFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYINPLLLSTEES---------------
PKCi_Hsap NFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEEC---------------
aPKC_Dmel NFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVNPLLMSLEDCLYGEDSSDYDSVADD
PKCz_Mmus NFDTQFTSEPVQLTPDDEDVIKRIDQSEFEGFEYINPLLLSAEES---------------
PKCi_Mmus NFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEEC---------------
pkc-3_Cele HFDHQFTDELPQLSPDNPDVIARIDQSEFDGFEYVNPLQMSREDS---------------
PKCi_Spur HFDPQFTEEPIQLTPDDPGVLSQIDQGEFEGFEYINPLLMSGEEC---------------
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque NFDPQFVTEPIQFTPDDPETIGHIDQSEFAGFEYINPLLMSKIEE---------------
PKCz_Hsap ------------------------------------------------------------
PKCi_Hsap ------------------------------------------------------------
aPKC_Dmel LSLLHLNSAAGAGGSVSSNNNLSQQQHYRQQQQQQYQPHSAYSQQQQQQQQHQHAAATSA
PKCz_Mmus ------------------------------------------------------------
PKCi_Mmus ------------------------------------------------------------
pkc-3_Cele ------------------------------------------------------------
PKCi_Spur ------------------------------------------------------------
AqueK019_Aque ------------------------------------------------------------
AqueK020_Aque ------------------------------------------------------------
PKCz_Hsap ------------V
PKCi_Hsap ------------V
aPKC_Dmel ASTSAATAATTSS
PKCz_Mmus ------------V
PKCi_Mmus ------------V
pkc-3_Cele ------------V
PKCi_Spur ------------V
AqueK019_Aque -------------
AqueK020_Aque ------------V