PLK1_Hsap MSAAVTA----------GKLA---------------------------------------
F55G1.8_Cele MQHVLRTR---------GN-----------------------------------------
plk-1_Cele MNRLPNIA----------KPP---------------------------------------
plk-2_Cele MQRVQPSA------------A---------------------------------------
PLK1_Spur MASRHKE-----------------------------------------------------
PLK1_Mmus MNAAAKA----------GKLA---------------------------------------
PLK_Ddis MVSINQN----------FKLPISMNSQPIQIQQQQFKQPQQQPQQKSNSCFSDQENYPAN
polo_Dmel MAAKP-------------------------------------------------------
CDC5_Scer MSLGPLKAINDKQLNTRSKLV---------------------------------------
CC1G_07437_Ccin MYQMNGY----------RMPP---------------------------------------
AqueK200_Aque MAHHLSEK---------DKLG---------------------------------------
*
PLK1_Hsap -----------------------RAPADPGKAG--------------------VPG----
F55G1.8_Cele ------------------------SAQ---------------------------------
plk-1_Cele -----------------------QKSN---------------------------------
plk-2_Cele -----------------------RVKS---------------------------------
PLK1_Spur ------------------------------------------------------------
PLK1_Mmus -----------------------RAPADLGKGG--------------------VPG----
PLK_Ddis IQPSSSTSSSSSSSIHITKSMVIRPPLESNQ-P--------------------QPQ----
polo_Dmel ------------------------------------------------------------
CDC5_Scer -----------------------HTPIKGNTAD-LVGKENHFKQ---TKRLD--PNNDHH
CC1G_07437_Ccin -----------------------AAPGPSSKRNPLVNAVNHHPNVMQMNAVPPVPAKAPA
AqueK200_Aque -----------------------S------------------------------------
PLK1_Hsap --V----------------------------------AAP--GAPAAAP---------PA
F55G1.8_Cele --------------------------------------------DKNKK---------HV
plk-1_Cele --------------------------------------------QRKEK---------AP
plk-2_Cele --------------------------------------------QKKEK---------AP
PLK1_Spur -----------------------------------------------DL---------RV
PLK1_Mmus --D----------------------------------AVP--GAPVAAP---------LA
PLK_Ddis --QQQQQQQTLQQIHHQQVQLQQQQSLQMQQQQLQQQQQQ--QQQQQMPPPQSLPNKSNE
polo_Dmel -----------------------------------------------ED---------KS
CDC5_Scer HQP----------------------------------AQ-K-KKREKLS---------AL
CC1G_07437_Ccin KGP----------------------------------SSPPLPRQNSKT---------RP
AqueK200_Aque ----------------------------------------------ASS---------LS
PLK1_Hsap KEIPEVL------VDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLK
F55G1.8_Cele PNVPPII------YD-DMQVPYEKGAFLGEGGFAHCFEFRKLDCNDRLAVKVVPKVILLK
plk-1_Cele PEVPALI------ADKDRGTYYEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVK
plk-2_Cele PDVPDVI------LDGERKTRYEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIK
PLK1_Spur KEVPDVV------TDPSTGKTYTKGRFLGKGGFAKCYELTDDATKQIFAGKVVSKALLVK
PLK1_Mmus KEIPEVL------VDPRSRRQYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLK
PLK_Ddis PQEPIVVYETIRSGDSKRLKEYRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQK
polo_Dmel TDIPDRL------VDINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIK
CDC5_Scer CKTPPSL------IK-TRGKDYHRGHFLGEGGFARCFQIKDD-SGEIFAAKTVAKASIKS
CC1G_07437_Ccin PSPPKVI------SDKAGRLQFNRVGFLGEGGFARVYEVQDP-RGSRLACKVVTKSALKT
AqueK200_Aque KPLKEFV------TNPDTKKRYEKGRFLGKGGFAKCYELICEETGTVYAGKIVAKELLVK
: . : : *:*:****: : . * * :.* : .
PLK1_Hsap PHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEP
F55G1.8_Cele STAREKLTREVEIHRQLSHRNIVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEH
plk-1_Cele QYQRDKMTQEVQIHRELGHINIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEP
plk-2_Cele QYQRDKMAQEVQIHRNLQHRNVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEP
PLK1_Spur PHQKDKMTMEIHIHKSLHHRHVVGFHSFFEDKENVYVLLELCRRRSLMELHKRRKAITEP
PLK1_Mmus PHQKEKMSMEISIHRSLAHQHVVGFHDFFEDSDFVFVVLELCRRRSLLELHKRRKALTEP
PLK_Ddis TRARSKLKSEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQKTVMDIHKKRKYLMEY
polo_Dmel HNQKEKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEF
CDC5_Scer EKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEP
CC1G_07437_Ccin KKAKTKLYAEIKIHRSLDHPNIVTFIDCFEDEDNVYITLELCPSGSLMDMLRRRRRFTEP
AqueK200_Aque PHQKEKMTQEIEIHRSLSHKHVVGFHGFFDDSNNVYILLELCKRRSLMELHKRRKALTEP
: * *: ** .: * ::* : *::. ::. **:* ::::: ::* . *
PLK1_Hsap EARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTL
F55G1.8_Cele EARFYTIQVAEGVKHLHNLQIIHRDLKLGNLFLNEHLQVKIGDFGLATFCEK-NEKKMTR
plk-1_Cele EARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNG-DERKKTL
plk-2_Cele EARYFTYQIVEGVLYLHNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCDN-DERKKTL
PLK1_Spur ETRYFMRQCILACQYLSKTKVIHRDLKLGNLFIDDNMELKVGDFGLATKVDFSGERKKTL
PLK1_Mmus EARYYLRQIVLGCQYLHRNQVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYEGERKKTL
PLK_Ddis ETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFID-NMRIKLGDFGLSTKVEH-GERKKTI
polo_Dmel ECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTL
CDC5_Scer EVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTI
CC1G_07437_Ccin ETRFFMVQLIGACHYMHTHQVIHRDLKLGNLFLDANMNVKVGDFGLAALIENPGERKKTI
AqueK200_Aque EVRYLFRQTVLAVDYLHDVKVIHRDLKLGNLFLNDDIEIKLGDFGLATRLEEDGERKKTL
* :: * . :: .::***:****:*:: :*:*****:: .*:* *
PLK1_Hsap CGTPNYIAPEVLS--KKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYS
F55G1.8_Cele GGTPNYIAPEVLN--ETGHAFEVDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNNDYV
plk-1_Cele CGTPNYIAPEVLN--KAGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYT
plk-2_Cele CGTPNYIAPEVLN--KIGHSFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYV
PLK1_Spur CGTPNYIAPEVLS--KKGHSYEVDLWSLGCIMYTLLVGKPPFETQSLKDTYQRIKRNEYR
PLK1_Mmus CGTPNYIAPEVLS--KKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYS
PLK_Ddis CGTPNYIAPEILD-NSNGHSYEVDVWSIGIILYTLLIGKPPFETSDVKHTYQRIKQNQYS
polo_Dmel CGTPNYIAPEILT--KKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYR
CDC5_Scer CGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFS
CC1G_07437_Ccin CGTPNYIAPEVLFDTANGHSFEVDIWSIGVILYTLVIGRPPFQTKEVKEIYKRIRDNEYE
AqueK200_Aque CGTPNYIAPEVLT--KKGHSYEVDIWSLGCILYTLLVGKPPFETKTLKDTYQRIKRNEYH
*********:* **::***:*::* ::* *:.* ***:: :: * :*: ::
PLK1_Hsap IPKH--INPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSI
F55G1.8_Cele VPEN--ASPTANRLIRSLLDPVPDRRPTAEAVLLDQFFKTTIEPTYPPVHQQ--------
plk-1_Cele IPSI--ATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKSGFMPTRLPVSCLTMVPKFGG
plk-2_Cele IPTS--ASAAASQLIRVLLDPVPSRRPNARAVCRDHFFKSGFMPARLPVSCLTMVPHLND
PLK1_Spur VPSH--VSTPARNLIVKLLKNDPTQRPHIDILLQDEFFTTGYLPPQLPTTCLTMAPRFQV
PLK1_Mmus IPKH--INPVAASLIQKMLQTDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSI
PLK_Ddis FPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFFTYSPIPKYLPVSSLTTAPSQST
polo_Dmel VPSY--LRKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRIGS
CDC5_Scer FPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFR-GTFPPSIPSTVMSEAPNFED
CC1G_07437_Ccin FPAERAISTAVKVLIQQILTPDPSQRPTLHEIIEDTFFTHGTVPAFIPTSAHDAAPDFRH
AqueK200_Aque IPHY--VGPEARTLISNLLRPNPANRPTAAEILKDPFFTCGHMPVRLPVSCLTTTPHFKK
.* :: :* * ** : :: * *
PLK1_Hsap APSSL-------------------------------------------------------
F55G1.8_Cele LHKEQ---D---------------------------------------------------
plk-1_Cele HETSMMEENVAP--------------------------------------------R-GV
plk-2_Cele DEY--AEENVSP--------------------------------------------S-GT
PLK1_Spur PVS---------------------------------------------------------
PLK1_Mmus APSSL-------------------------------------------------------
PLK_Ddis INQNM-------------------------------------------------------
polo_Dmel NDTIE-------------------------------------------------------
CDC5_Scer IPEEQSLVNFKDCMEKSLLLESM---SSD------------KIQRQKRDY---ISSIKSS
CC1G_07437_Ccin ISRSASEANLKRLRRYA-LLDTDFNNTPSPVQNATTRNITSSIAQQEKEFQRAVQPG-SP
AqueK200_Aque AAESA-------------------------------------------------------
PLK1_Hsap ----D-PSNRKPLT-VLNKGLEN-------------------------------------
F55G1.8_Cele ------VKYFAPIN-PVLPHVEEP------------------------------------
plk-1_Cele ----D-ARSQRPLN-GRAG-LS--------------------------------------
plk-2_Cele ----I-D-QRGPHQAGRSG-LS--------------------------------------
PLK1_Spur -------SGRRPLL-EVNGQDEN-------------------------------------
PLK1_Mmus ----D-PSSRKPLK-VLNKGVEN-------------------------------------
PLK_Ddis ---------GRPLS-EKTNIVNQQHLQLAGTTSPTKNNNHHYQQYQQQPQQQYNNNYQQS
polo_Dmel ----D-SMHRKPLM-EMNGIRPD-------------------------------------
CDC5_Scer IDKLEEYHQNRPFL-P-----HS-------------------------------------
CC1G_07437_Ccin ISALL-SSARQPLL-VGPTAGGG-------------------------------------
AqueK200_Aque ------VSGRKPLS-DRNPMTDA-------------------------------------
*
PLK1_Hsap ------------------------------------------------------------
F55G1.8_Cele ------------------------------------------------------------
plk-1_Cele ------------------------------------------------------------
plk-2_Cele ------------------------------------------------------------
PLK1_Spur ------------------------------------------------------------
PLK1_Mmus ------------------------------------------------------------
PLK_Ddis FSPKKQINNMNNNNNNNNNNNNNNNNNNNNNNNNLKQYNYSNNNINYNNNNNNINNQFAN
polo_Dmel ------------------------------------------------------------
CDC5_Scer ------------------------------------------------------------
CC1G_07437_Ccin ------------------------------------------------------------
AqueK200_Aque ------------------------------------------------------------
PLK1_Hsap PLPERP------------------------------------------------------
F55G1.8_Cele ISPIYQEVAN-------------------E-------E----------------T-----
plk-1_Cele ALPQHIVSNN-------------------A-------D----------------R-----
plk-2_Cele AIPAHLVSRN-------------------S------------------------------
PLK1_Spur VPPGREQSGKPHR----------------K-------H----------------S-----
PLK1_Mmus PLPDRP------------------------------------------------------
PLK_Ddis LSPNSQQKLSEVENDDFHYRKLRRLEKMKE------NDLKTQLLIKQQYTNMNEN-----
polo_Dmel D--TRLEST-FLK----------------A-------N----------------L-----
CDC5_Scer LSPGGTK-----Q----------------KYKEVVD------------------------
CC1G_07437_Ccin GNPGAVRESPLLR----------------KLQAVKESPLGRRS-----------VTRTAN
AqueK200_Aque M----DTAGGVLK----------------P------------------------G-----
PLK1_Hsap ------REKEEP------------VVRETGEVVDCH-LSDMLQQL-HSVNASKPS-----
F55G1.8_Cele --S---EIR-RF------------VKTEQASSFGDE-LSQLQAQI-SHILQNVVA-----
plk-1_Cele --E---RAQQQA------------AEATFREPEDAY-LSQLFHQV-AVLLEQRIP-----
plk-2_Cele --E---RQ-QTH------------RMEAYRQPTDCY-LSNLLAQV-NDLLATPTA-----
PLK1_Spur --D---RKENGG------------GKPKVYQPKEDH-LASLKVHL-TSVVAAKPS-----
PLK1_Mmus ------REKEEP------------VVRETNEAIECH-LSDLLQQL-TSVNASKPS-----
PLK_Ddis -QQ---QQQQQQ------------QQQQQQQQQQQR-VNNNINNNGNTVTVTTGNNTVNV
polo_Dmel --HD--AITASA------------QVCRHSEDYRSD-IESLYQQL-TNLINGKPR-----
CDC5_Scer ----IEA---------QRRLNDLAREARIRRAQQAVLRKELIATS-TNVIKS--------
CC1G_07437_Ccin GYEEDERGKRRMVIETEEEEEDMR---QRRKELEAQ-KARIVAQM-APVKEEVER-----
AqueK200_Aque --G---GATATH------------FVEKIQGSEDWH-LNSLLLQL-SSCLTSCPS-----
PLK1_Hsap --ERGLVRQ---------------------------------------------------
F55G1.8_Cele SKNKSSTRF---------------------------------------------------
plk-1_Cele GLEEEEAAL---------------------------------------------------
plk-2_Cele DIDDAEAAL---------------------------------------------------
PLK1_Spur --EKADIRL---------------------------------------------------
PLK1_Mmus --ERGLVRQ---------------------------------------------------
PLK_Ddis QIKELETKI---------ANNHI--SDSPPV-----------------------------
polo_Dmel --ILQGNLG---------------------------------------------------
CDC5_Scer ------------------------------------------------------------
CC1G_07437_Ccin --EEREDEDDEEEDEDGMGGRRRAPPPPPPVFKREREHQKGSSAGSNRYAGEDVENVPPR
AqueK200_Aque --TKNPAHY---------------------------------------------------
PLK1_Hsap ------------------------------------------------------------
F55G1.8_Cele ------------------------------------------------------------
plk-1_Cele ------------------------------------------------------------
plk-2_Cele ------------------------------------------------------------
PLK1_Spur ------------------------------------------------------------
PLK1_Mmus ------------------------------------------------------------
PLK_Ddis ------------------------------SSNNNYPQQIQKQQPNFN------------
polo_Dmel ------------------------------------------------------------
CDC5_Scer --------------EIS-----------------------------LRILASECHLTLNG
CC1G_07437_Ccin LGGAQQARRDVAKGKAVERPRAREKENVPVSSSNPAPA-----APKLNGFDAA-AQILTM
AqueK200_Aque ------------------------------------------------------------
PLK1_Hsap -------------EEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIL
F55G1.8_Cele -------------GLNHSPEATPIFWVSQWVHFPN-HGIGYRLCENSSGMLFNDNTQMKV
plk-1_Cele -------------DGYQSPECLPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIML
plk-2_Cele -------------DSYQSPEALPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIML
PLK1_Spur -------------DEAEDPAAAPILWVSKWVDYSDKYGLGYQLCDGSVGVLFNDSTRLLL
PLK1_Mmus -------------EEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIL
PLK_Ddis -------------NEFYLGMPNNLVYISQYADFTNKYGLAYVLSNSYVGAYFNDSTKIVT
polo_Dmel -------------DENTDPAAQPLFWISKWVDYSDKYGFGYQLCDEGIGVMFNDTTKLIL
CDC5_Scer IVEAEAQYKMGGLPKSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLR
CC1G_07437_Ccin AFDARAAGRVFRSPLGDQPLPEERVFIVSWVDYCNKYGMGHF------------------
AqueK200_Aque -------------DEAEDPASMPVFWICKWVDYTDKYGLGYQLCDNSIGVLFNDFSKLLL
. : .:..: : :*:.:
PLK1_Hsap YNDGDSLQYIER------DGT-ES----YLTV--SSHPNSLMKKITLLKYFRNYMSEH--
F55G1.8_Cele NSAGNQLTFVDE------NNT-EQ----FYTMN-DQVPMNLQTKINIFSNVQSYMNTH--
plk-1_Cele DQAGNELTYIEK------SNK-EH----YFSMHSGEMPGLLNKKVTLLKYFRSYMNDH--
plk-2_Cele DTAGTQLTYIEK------TEK-EH----YFDME-SAIPSGLQKKMTLLKYFRSYMNDH--
PLK1_Spur HANADTLEYIER------DGN-EK----YCRL--GSYDSTLHKKVTLLKYFRNYMSEH--
PLK1_Mmus YNDGDSLQYIER------DGT-ES----YLTV--SSHPNSLMKKITLLNYFRNYMSEH--
PLK_Ddis LIESEIAYYMEHAKGTDGDGR-RV----LNVT--QQHPHDTQKKVTLIKYFLNHFTNSDT
polo_Dmel LPNQINVHFIDK------DGK-ET----YMTT--TDYCKSLDKKMKLLSYFKRYMIEH--
CDC5_Scer LADAEEFWYISY------DDR-EGWVASHYLL--SEKPRELSRHLEVVDFFAKYMKAN--
CC1G_07437_Ccin -------DYISS------RHHGSIYLRKSFTI--DAYPDELKSKVYLLKHFEKYIMER--
AqueK200_Aque GADGESMQHISQ------NMT-EQ----FLTL--SQYPESMHKKVTLIKYFRDYMSEH--
.:. :: :.. . ::
PLK1_Hsap ---LLKAGANI-------------------T----PR--EGDELARLPYLRTWFRTRSAI
F55G1.8_Cele ---LEADTH-L-----------------EAEDQCVNKVPPLRNFARLPTIQNWFETKSAV
plk-1_Cele ---LVKAGEGS-------------------E----QR--AGDDLARLPTLRVWFRTKSAI
plk-2_Cele ---LLQAGQQV-------------------T----RK--VGDDLARLPTLRVWFRTKSAI
PLK1_Spur ---LLKAGAAM-------------------T----PR--ESDSMARLPFLQSWFRTKSAI
PLK1_Mmus ---LLKAGANI-------------------T----PR--EGDELARLPYLRTWFRTRSAI
PLK_Ddis TNLLINTGATSSSINNNNNNNVENVTNNNNN----NS--NNSSNINPIYVKKWIKFDNGI
polo_Dmel ---LVKAGANN-------------------V----NI--ESDQISRMPHLHSWFRTTCAV
CDC5_Scer ---LSRVST-F-------------------G----RE--EYH--KDDVFLRRYTRYKPFV
CC1G_07437_Ccin ---LYGEYE-Y-------------------T----FE--DVERTKGMEWVQKYLRMKHVI
AqueK200_Aque ---LLKAGGSV-------------------G----ER--EIDDGVRLPFLRAWSRTRSAI
* :: : . :
PLK1_Hsap ILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKEL---AS
F55G1.8_Cele IFHLSNGTVQINF-LDHVKMVLCPLLKSVTFIEENKRVSTFTFANILTNSCPKKY---LS
plk-1_Cele VLHLSNGTVQINFFNDHVKMMMCPLMQAVTFIDQNKRMLTYKLNNLQRNGCPEKF---LH
plk-2_Cele VLHLSNGTVQINFFNDHIKMVLCPLMQAVTFIDENKRMFTYKFSHLAENGCPEKF---LH
PLK1_Spur VLHLSNGTVQINFFEDHTKLIVCPMMGAATYIDAKRNFRTFRLNLIEKHGCTPDL---YD
PLK1_Mmus ILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKEL---AS
PLK_Ddis AFRLSDKTIQVNYL-DKSRIIVSS-KDMVTFVPYRGQIITGTLNYFK-NG-DKKI---SE
polo_Dmel VMHLTNGSVQLNF-SDHMKLILCPRMSAITYMDQEKNFRTYRFSTIVENGVSKDL---YQ
CDC5_Scer MFELSDGTFQFNF-KDHHKMAISDGGKLVTYISPSHESTTYPLVEVLKYGEIPGY--PES
CC1G_07437_Ccin VFKMSHDVLQFNF-YDHSKLILSSNGLLITHIDKSYKMTRWTLEDVMAFSLHPPQGASGD
AqueK200_Aque VFHLSNGTLQINFFQDHTKIIICPLMQAVTYIDEQKPSSQSDS-----------------
:.::. .*.*: *: :: :. *.:
PLK1_Hsap RLRYARTMVDKLL----------SSRSA--------------------------------
F55G1.8_Cele RIEYAQAKIKLLR----------PTNNQEH---------------------V---VYV--
plk-1_Cele RLKYAKTMIERLM----------SDANVVS---------------------Q---NPA--
plk-2_Cele RIQYAKCMIQRLV----------EEHTKEE---------------------TKHNAPA--
PLK1_Spur RIKYANNMVKNML----------DKKTT--------------------------------
PLK1_Mmus RLRYARTMVDKLL----------SSRSA--------------------------------
PLK_Ddis KIKYIYGTLSNNL---------YSKKPESS----------------------FQQLPQQ-
polo_Dmel KIRYAQEKLRKML----------EK-----------------------------------
CDC5_Scer NFREKLTLIKEG------------------------------------------------
CC1G_07437_Ccin EIKFNQRMVDKLKYCKEVLVSIRSATSAGAGSGGGGGGERGTSTERGEKERGGERAERGE
AqueK200_Aque -------------------------PSL--------------------------------
PLK1_Hsap ---------------------------------------------------------SNR
F55G1.8_Cele ----------------------DSPCRPT------TSNT---------A---HGAPLASS
plk-1_Cele ----------------------RQPDMPRSMAAARSASAGSRGPNQAASHLPQSASGSNI
plk-2_Cele ---------------------ANAVRLPSTSSNVRLESA---------A---DIQPAYPS
PLK1_Spur ------------------------------------------------------TTTAAA
PLK1_Mmus ---------------------------------------------------------SNR
PLK_Ddis QYQQPQHYQQQTQQPQPQ---PQQQQLPQQLPQPQQSPAKQHQYQPNQIQY-QQSIPQPQ
polo_Dmel ------------------------------------------------------------
CDC5_Scer -----------------------------------------------------LKQKSTI
CC1G_07437_Ccin RRMGGDDERERDRERERADRGVERERLGSG--REAGSST---------A---TLNRRTSK
AqueK200_Aque ------------------------------------------------------LIVLSV
PLK1_Hsap LKAS
F55G1.8_Cele RYLA
plk-1_Cele HPRR
plk-2_Cele SSRR
PLK1_Spur VPAH
PLK1_Mmus LKAS
PLK_Ddis LINQ
polo_Dmel -MFT
CDC5_Scer VTVD
CC1G_07437_Ccin LSMR
AqueK200_Aque AVSV