Protein (view, download) , Domain (view, download)
E02D9.1_Cele     MLTEPILFTKDKSLQ-R-------------ANKI-TKKHFH-FL--FLSISLQAIVS--V
F35C8.1_Cele     MSQPPGRRMP-------RPKLDL-PP--LR------ET----------------------
F35C8.2_Cele     MPTFG-RRVP-------RPKLDL-PA--LR------ET----------------------
MKK1_Scer        MASLFRPPESAK-CNPNSPRLKL-PL--LRNNQV-DENNIY-LT--SNGSSTTAYSSH-T
MKK2_Scer        MASMFRPPESNR-SHQKTPKLTL-PVNLVQNAKS-TNDGQH-LNRSPYSSVNESPYSN-N
PBS2_Scer        MEDKFANLSLHEKTGKSS----I-QL---NEQTG-SDNGSA-VKR--T-SSTSSHYNN-I
STE7_Scer        MFQRKTLQRRNLKGLN----LNLHP-DVGNNGQL-QEKTETHQGQSRIEGHVMSNINA-I
1557_Tthe        MLNDF-------------------------------------------------------
1909_Tthe        MNEEQLQQCSNLKEGNE----SS-E-QQ-QEPQPQ-QQIAANVTPKNEKKEESSN-NE-S
26687_Tthe       MEINSLKNSGSFST------------KIQNLNKL-QEQISQV-CEE--------DIDQVT
Mek1_Ddis        MNTNTNTNTNISSSGNN--IINT-P-TT-NNNNKNNNNNNNNNNNSNNSNNNSSN-NN-N
12278_Tthe       MADKKKGLSFNM--------------NLTQ------------------------------
CC1G_01983_Ccin  MEAKTTTLPRPMGPRGPTPGRRP-PFPTIRTTG-----------NLP-TS----------
CC1G_14241_Ccin  MASNHNNRFPTSTPIPPS------------------------------------------
                 *

E02D9.1_Cele     HFSIMSGIRTFLVY------------FELE-----KCIG----------E----------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        PEPLTSSTSTLFSQ------------TRLHPSDSSM-------------T---LNT-MK-
MKK2_Scer        STSATSTTSSMASN------------STLLYNRSS------------------TTT-IK-
PBS2_Scer        NADLHARVKAFQEQRALKRS------ASVGSNQSEQDKG----------S---SQS-PKH
STE7_Scer        QNNSNLFL-----RRGIKKKLTLDA------------------FGD-DQAISKPNT-V-V
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NGEKTFYL-----H-KLKKKVNLNIKIPNQQKNEDYADLTNGTLFNGNVIIDKEGVKG-L
26687_Tthe       PNNQ--------------------------------------------------------
Mek1_Ddis        NNNNAVGV-------KTGKKVNLKVETPVQNNENSYSLTTSGTFKEGDLLINKKGLLI-K
12278_Tthe       -ENM--------------------------------------------------------
CC1G_01983_Ccin  ---------------------------PIQPA----------------------------
CC1G_14241_Ccin  ---LQAKLAAFQANRAAPTN------NAVRSLEDAMNGV----------S----------


E02D9.1_Cele     --LAEPRCLQLPEHLWR-------FWDILIAELKSEIPEI--------------------
F35C8.1_Cele     ------------------------I------------PEV--------------------
F35C8.2_Cele     ------------------------I------------PEV--------------------
MKK1_Scer        -KRPAPPSLPSLS--INSQSKCKTL------------PELVPIADVSDGKHDLG--LKQR
MKK2_Scer        -NRPVPPPLPPLV--LTQK------------------------------K--DG--IEYR
PBS2_Scer        IQQIVNKPLPPLP--V--------------------------------------------
STE7_Scer        IQQPQN------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        G-----------------------------------------------------------
26687_Tthe       -----N------------------------------------------------------
Mek1_Ddis        GESPKN------------------------------------------------------
12278_Tthe       -----K------------------------------------------------------
CC1G_01983_Ccin  ----DPPMLAPPT--L-------GI------------PQRG-----KKPI--LGLKIDKN
CC1G_14241_Ccin  ---IAPPAVPPPP--L--------------------------------------------


E02D9.1_Cele     ------------------------------------------------R-----N--N--
F35C8.1_Cele     ------------------------------------------------L-----K--N--
F35C8.2_Cele     ------------------------------------------------L-----K--N--
MKK1_Scer        VIAENELSGN-------SDLTP------------------------SSM-A----SPFS-
MKK2_Scer        VAGDSQLSERFSNLH--VDITY------------------------KELLS---SAPIS-
PBS2_Scer        -AGSSKVSQRMSSQV--VQASS------------------------KSTLK---NVLDNQ
STE7_Scer        -----------EPVLVLSSLSQ------------------------SPC-----VSSS--
1557_Tthe        ------------------------------------------------------------
1909_Tthe        ----INI--------FHSSYKILLHTTIFLFGECTFKKISLIFFFYLLL-HSSSTIPLKD
26687_Tthe       -----------Q---RMTSLSL------------------------QYI-----VSPN--
Mek1_Ddis        ----SSVNDRNKNKSLHSNLNP------------------------QLL-----ASPTSS
12278_Tthe       -----------K---TESDV----------------------------------------
CC1G_01983_Ccin  NTSFELYAGG-------PSGPP------------------------ESYM-----SP---
CC1G_14241_Ccin  -KPGPSLAARMQALR--GQSTP------------------------GRRPK---------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------HTNTSSPYL---------
MKK2_Scer        ----------------------------------------TKLSNIDTTFI---------
PBS2_Scer        ET-------------QNITDVNINIDTTKITATTIGVNTGLPATDITPSVSNTASATHKA
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QLEELKQQQHQNKDSNDKNNQKQNVEQ--------------------------------K
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ESMDFNQGFYNNNNNNNNNNNNNNLNNF-------------------------------N
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  --------------------------------------------GDDAR-----------
CC1G_14241_Ccin  --------------------------------------PAFSLHDIDPSLGGISDAGL--


E02D9.1_Cele     ---------------------------FKLK---YN-----------------DVDGAIL
F35C8.1_Cele     ---------------------------GALG---Y-------------------------
F35C8.2_Cele     ---------------------------GALG---Y-------------------------
MKK1_Scer        ---------------------------------------------------RND-----L
MKK2_Scer        ---------------------------------------------------KKD-----L
PBS2_Scer        QLLNPNRRAPRRPLSTQHPTRPNVAPHKAPAIINTPKQSLSARRAVKLPPGGMS-----L
STE7_Scer        ---------------------------SSLS---T-------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        ----------------------NA-------------Q------------DQKQ-----Q
26687_Tthe       ---------------------------QSIG---F-------------------------
Mek1_Ddis        ----------------------NL-MNNGID---SPQL------------SGIS-----I
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  -----GAGRPRPPLSLHS-----------------------------------------A


E02D9.1_Cele     KVR---------------------------------------------G-----------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        SNS-----------------------------V-GSD------------FS--------N
MKK2_Scer        DTP-----------------------------E-GEDSY----------PS--------T
PBS2_Scer        KMPTKTAQQPQQFAPSPSNKKHIETLSNSKVVE-GKRSN----------PG--------S
STE7_Scer        --PCIIDAYSNNFGL--------SP--SSTNST-PS---------TIQGLS---------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        TNQSQI------Q-TDHNNNNQNSQ--NGNQQQ-GSRLNSGNIAIINSKTK--------Q
26687_Tthe       -------------SK--------SP--SSKSLNLKF---------DLECLSKNKTQIEEN
Mek1_Ddis        STPTSSHSFNNTFTNYYNNNNNYN---NYNNNN-NSNNNNNNYNNSNNNFN--------N
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ----------------------------------TIRPG----------PA--------T
CC1G_14241_Ccin  AK-------PPAFA----------------------------------------------


E02D9.1_Cele     -----------------------------------------ADDFEKFSE-R-------L
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        LISAYEQSSSP-IKS--------SSQPKSS---------------------SE--SY--I
MKK2_Scer        LLSAYDFSSSG-SNS--------APLSANN---------------------II--SC--S
PBS2_Scer        LINGVQSTSTSSSTEGPHDTVGTTPRTGNSNNSSNSGSSGGGGLFANFSK-Y-------V
STE7_Scer        ----------------------------------------------NIAT-PV-ENE---
1557_Tthe        ------------------------------------------------------------
1909_Tthe        VITKAN--------------------------ITQ------NN-LANSNVTYKTPQDQMK
26687_Tthe       IIKQEK--------------------------IMD------QNLAEMFQK-LQLENK---
Mek1_Ddis        FNNYNN--------------------------YGN------NNNFNNFNA-LQSSSNSSF
12278_Tthe       ----------------------------------D------ILILQRFKE-LV-QQS---
CC1G_01983_Ccin  IQPGGDTGTTTVPAS--------KPGASEP--------------ITRIQD-LL--RD--L
CC1G_14241_Ccin  -----------------------TP-------------------FANFSK-I-------V


E02D9.1_Cele     ENT----DE-----N-EEIVLILENISSK--NDESSGNSQNVRIFPSELQR-GKYVGNGM
F35C8.1_Cele     -----------------------ICV-----------SGRILSVPENLLY-GGERIGNGE
F35C8.2_Cele     -----------------------ICL-----------SGRNLNVPEDMLH-GGVRIGSGE
MKK1_Scer        DLN----S-------------------VRD-VDQLDENGWKYANLKDRIET-LGILGEGA
MKK2_Scer        NLI----Q-------------------GKD-VDQLEEEAWRFGHLKDEITT-LGILGEGA
PBS2_Scer        DIK----S------GSLNFA-GKLSLSSKG-IDF--SNGSSSRITLDELEF-LDELGHGN
STE7_Scer        -------HSISLPPLEESL--SPAAADLKDTLS-GT--SNGNYIQLQDLVQ-LGKIGAGN
1557_Tthe        ------------------------------------------------------------
1909_Tthe        DKQASQDSA-----EN-----QYIE-------------INGNHLLISELRR-VKVLGHGS
26687_Tthe       -------QN-----II-----EQLDKDMR-VVN-IL--LKNVDFKYEDFEV-VSELGKGA
Mek1_Ddis        DISSS--GS-----SN-----NYLNNSANN-HP-HY--DTNLSYDLKDLKI-IRVLGRGA
12278_Tthe       -------NC-----FD-----EYISHDKK-IFK-IM--QKNVDFKLEDFET-ISELGRGA
CC1G_01983_Ccin  NLT----Q----PPPTVNPS-P-----GDSILSKIE-DPSSTQWSDECFEE-ISRLGEGA
CC1G_14241_Ccin  DPS----G-------ALNFS-GKAILHASG-VNF--ENGSSFAINRDQLQLDDEELGRGN


E02D9.1_Cele     HATVRMALHEKTQKWYVIKTILSQ-------NTDKT---EYEKEILAY-EECSQSDYVVG
F35C8.1_Cele     GQSAVYRL-IYNGKLIARKDVAVRLPKGVDQDSTNKLMAKKLREVNVI-NGCAPCPFIVH
F35C8.2_Cele     GQSAVYRL-IYNGMVIARKDVAVRLPQGGDEDSTNKLMAKRLREVNVI-NGCAPCPFIVH
MKK1_Scer        GGSVSKCKLKNGSKIFALKVINTL-------NTDPEYQKQIFRELQFN-RSFQ-SEYIVR
MKK2_Scer        GGSVAKCRLKNGKKVFALKTINTM-------NTDPEYQKQIFRELQFN-KSFK-SDYIVQ
PBS2_Scer        YGNVSKVLHKPTNVIMATKEVRLE--------LDEAKFRQILMELEVL-HKCN-SPYIVD
STE7_Scer        SGTVVKALHVPDSKIVAKKTIPVE-------QNNSTIINQLVRELSIV-KNVKPHENIIT
1557_Tthe        ---------------------------------------------KVLLTQYT-HPNLIT
1909_Tthe        SGLVELAVHDATGIVIGIKSIPLL--------MNSSFRKQLDQELKTL-IQCE-SDSIVK
26687_Tthe       FGKVYKVCHKKDGKIYAMKEIIMV--------DDIELRQKILMEVKTL-FICQ-SPYIVT
Mek1_Ddis        GGVVKLAYHETSGTYIALKVITLD--------IQENIRKQIILELKTL-HKTS-YPYIVS
12278_Tthe       SGRVFKVKHKETGKFYAKKEIRIN--------DDEMFQKQLIWEIKTL-FSCN-SPHIVQ
CC1G_01983_Ccin  GGAVHKVKDKRNGMIMARKTITTR----------EAPMKQLLRELTIM-SSTK-HVNIIT
CC1G_14241_Ccin  YGTVKKVLHKPTNVAMAMKEIRDS---------IQANSPAIIMELDVL-HRAV-APEIVE
                                                                          ::

E02D9.1_Cele     YHGCEVSS----IKKELVLEYMDKGDFR--------------------------------
F35C8.1_Cele     FFGYYVHKYRDCVKIHIFMEEMALSA-SVLKT---EAL----------------------
F35C8.2_Cele     FFGYYVHKYKDCVKIHIFMEEMALSA-SVLKK---EVL----------------------
MKK1_Scer        YYGMFTDDE--NSSIYIAMEYMGGRSLDAIYK---NLL----------------------
MKK2_Scer        YYGMFTDEQ--SSSIYIAMEYMGGKSLEATYK---NLL----------------------
PBS2_Scer        FYGAFFIE----GAVYMCMEYMDGGSLDKIYD---ESS----------------------
STE7_Scer        FYGAYYNQHI-NNEIIILMEYSDCGSLDKILSVYKRFV----------------------
1557_Tthe        CFGAYYEE----GTIKIILELMDFGSIRNLID---M------------------------
1909_Tthe        CYGAYIQK----CMINITLEYMDLGTVHDLVK---K------------------------
26687_Tthe       YYGAFYTE----GKLHIILEYMDVGTLDSLLK---K------------------------
Mek1_Ddis        FYDAFYTE----GSIFIALEFMELGSLSDIMK---K------------------------
12278_Tthe       YYCAFYTE----CMLHLILEYMDMGTLDTILK---K------------------------
CC1G_01983_Ccin  FYGAYMSPS--SSEIKIIMEYCEGGSLESVGK---RIR----------------------
CC1G_14241_Ccin  FYGAFFIE----SCVYYCMEYMDAGSLDKLIQ---SNSQPPQPQIPKPPSSDPIQTDASS
                  .                :*

E02D9.1_Cele     -----------------------------------------P------FGILPFSVHQ--
F35C8.1_Cele     ----------------------------------------KQ------GGAIPEFVIG--
F35C8.2_Cele     ----------------------------------------KR------GGIVPEFVIG--
MKK1_Scer        ----------------------------------------ER------GGRISEKVLG--
MKK2_Scer        ----------------------------------------KR------GGRISERVIG--
PBS2_Scer        -----------------------------------------E------IGGIDEPQLA--
STE7_Scer        ----------------------------------------QRGTVSSKKTWFNELTIS--
1557_Tthe        ------------------------------------------------LKEINYCYLSKI
1909_Tthe        ------------------------------------------------VGPLPEIIVA--
26687_Tthe       -----------------------------------------A------GGKVSEVVLK--
Mek1_Ddis        ------------------------------------------------TSTIPEPVLG--
12278_Tthe       ------------------------------------------------TKQVSEPILI--
CC1G_01983_Ccin  ----------------------------------------ER------GAIVGEKIAG--
CC1G_14241_Ccin  PEYSFAMPFVEEDLDLTKDENFEPYNRAFNRTCPPPIPSTYS------GGPIPEAILG--
                                                                    .

E02D9.1_Cele     ----------SVALSLIRAIRHVWNSGPGYIHRDIKPENILVN-SQGYVKICDFGAAKRI
F35C8.1_Cele     ----------RIVCSVIHAMWFLKD-RLQIIHRDIKPGNILID-YDGRVKICDFGICGIL
F35C8.2_Cele     ----------RIACSVIHAMWFLKE-KMQIIHRDIKPGNILID-YDGRVKICDFGISGIL
MKK1_Scer        ----------KIAEAVLRGLSYLHE-K-KVIHRDIKPQNILLN-ENGQVKLCDFGVSGEA
MKK2_Scer        ----------KIAESVLRGLSYLHE-R-KVIHRDIKPQNILLN-EKGEIKLCDFGVSGEA
PBS2_Scer        ----------FIANAVIHGLKELKE-QHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNL
STE7_Scer        ----------KIAYGVLNGLDHLYR-QYKIIHRDIKPSNVLIN-SKGQIKLCDFGVSKKL
1557_Tthe        LCNQKYQYHFFILKQLLKGLEFLHK-ERHQVHRDIKPENILIN-KRGNVKLTDFGISKQL
1909_Tthe        ----------IMAIQVLKGLDYIHN-KAKVIHRDIKPSNLLVN-SKGQVKIADFGVSANL
26687_Tthe       ----------YLTYQILKGLKYLHK-DLHIIHRDIKPGNILVN-SKGEIKISDLGICGAI
Mek1_Ddis        ----------KIAFQVLQGLVYLHR-KLHLIHRDIKPSNILVN-NKGEAKIADFGVSGQL
12278_Tthe       ----------YTTYQIIKGIHYLHK-DLKIIHRDLKPGNILVN-SEGEIKISDLGICGKV
CC1G_01983_Ccin  ----------RLAEGVLQGLSYLHS-K-KTIHRDIKPSNILLS-KEGVVKLCDFGVSGEL
CC1G_14241_Ccin  ----------RIAASMVRGLKFLKD-ELNIIHRDVKPTNVLVN-CKGQVKLCDFGVSGQL
                                ::..:  :       :***:** *:* .   *  *: *:* .

E02D9.1_Cele     DNTYRIASSAAGTQMYQAPEQQMGQ-----------------------------------
F35C8.1_Cele     ENSI--AVSDTGCQQYTAPEILVKGV-------------------------------SNS
F35C8.2_Cele     QDSI--AVSATGCQQYTAPEINELAM-------------------------------VHS
MKK1_Scer        VNSL--ATTFTGTSFYMAPERIQGQ-----------------------------------
MKK2_Scer        VNSL--AMTFTGTSFYMAPERIQGQ-----------------------------------
PBS2_Scer        VASL--AKTNIGCQSYMAPERIKSLN-------------------------------PDR
STE7_Scer        INSI--ADTFVGTSTYMSPERIQGN-----------------------------------
1557_Tthe        EKTQQLCMTYVGTTLYMSPERLIGN-----------------------------------
1909_Tthe        ESAVE-VKNWVGTVTYMSPERFRGQ-----------------------------------
26687_Tthe       NATLDERQTFVGTSIYMSPERLSGE-----------------------------------
Mek1_Ddis        QHTLSKAVTWVGTVTYMSPERISGR-----------------------------------
12278_Tthe       NGTMDQKNTFVGTTIYMSPERLNGD-----------------------------------
CC1G_01983_Ccin  ILSQ--AGTFTGTSFYMAPERIQGK-----------------------------------
CC1G_14241_Ccin  DKSM--AKTNIGCQSYMAPERIRGESRVVGAVPASEGGTGTAAAAQGGVPGTAALADELY
                   :     .  *   * :**

E02D9.1_Cele     -DYSEKVDIWCFGLTLWEFAIGPNLE---EYL----------------------------
F35C8.1_Cele     PGYSIKSDIWSLGITIFELATLRYPYPVG-------------------------------
F35C8.2_Cele     PGYSIKSDIWSLGITIFELATL--------------------------------------
MKK1_Scer        -PYSVTSDVWSLGLTILEVANGKFPCSSEKMA----------------------------
MKK2_Scer        -PYSVTCDVWSLGLTLLEVAGGRFPFESDKIT----------------------------
PBS2_Scer        ATYTVQSDIWSLGLSILEMALGRYPYPPETY-----------------------------
STE7_Scer        -VYSIKGDVWSLGLMIIELVTGEFPLGGHND-----------------------------
1557_Tthe        -QYGLRSDIWSVGLVIIELATGLYPYDVKN------------------------------
1909_Tthe        -AYTANTDIWSLGLTICECALGTYPYFDSNQYEK--------------------------
26687_Tthe       -SYSVKTDIWSFGLLLLEFSESKNPLQLNE------------------------------
Mek1_Ddis        -SYSFDSEIWSLGLTILECAIGKFPYGSNLPHQQQQPLQQQQQQQQQQQQPLQQQQQQQQ
12278_Tthe       -SYTMKTDIWSVGLLLIEFSEGKHPIQASN------------------------------
CC1G_01983_Ccin  -EYTIRSDVWSTGISLLELVQNRFPFPPD-------------------------------
CC1G_14241_Ccin  GAYTVSSDVWSLGLSIIELGLGRYPYPPETY-----------------------------
                   *    ::*. *: : *

E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        ------------------------------------------------------------
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        QQQQPLQLQLQNLDINNSNNNIRNSNNNNNNNNNNNNNNNNNNNNNVLDISNGGLVDSGS
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ---NG---LSSYEEITV--------EP---------------------------------
F35C8.1_Cele     -----FSEFTLLSAIVTTPAPYLER-----------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ---ANIAPFELLMWILTFT-PELKDEP---------------E-----------------
MKK2_Scer        ---QNVAPIELLTMILTFS-PQLKDEP---------------E-----------------
PBS2_Scer        -----DNIFSQLSAIVDGPPPRLPS-----------------------------------
STE7_Scer        ---TPDGILDLLQRIVNEPSPRLPK-----------------------------------
1557_Tthe        -----KSIVQFVSNILQSKEPTLPD-----------------------------------
1909_Tthe        --KENLSFWELLEYFNMKPAPRLPE-----------------------------------
26687_Tthe       ----NASFFEILAKVMNFSIPELNS-----------------------------------
Mek1_Ddis        SVPEGMGFWVLLDCIVKEEVPILPS-----------------------------------
12278_Tthe       ------NFFEVLNNIIDFKIPPLKN-----------------------------------
CC1G_01983_Ccin  -----LPPIELMMYITNSEPPRLEDEP---------------------------------
CC1G_14241_Ccin  -----SNVFAQLTAIVHGPPPCLPSGPPPPLSPDDDSSFEEPVLPPTLDDQDPLISPTTG


E02D9.1_Cele     --IDGFPESLAVLISNCLRRQPSARWNADQIE----------QSDYLRDLPEPNR-QSVA
F35C8.1_Cele     ---VTF------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        -SNIIWSPSFKSFIDYCLKKDSRERPSPRQMI----------NHPWIKGQMKKNV--NME
MKK2_Scer        -LDISWSKTFRSFIDYCLKKDARERPSPRQML----------KHPWIVGQMKKKV--NME
PBS2_Scer        ---DKFSSDAQDFVSLCLQKIPERRPTYAALT----------EHPWLVKYRNQDV--HMS
STE7_Scer        --DRIYSKEMTDFVNRCCIKNERERSSIHELL----------HHDLIMKYVSPSKDDKFR
1557_Tthe        --NGKYSAALMDFVKKCVAKEQKDRLDISDLL----------KHEWITQYNMADD--KQI
1909_Tthe        ----NYSEEMKDFVAKCFKKSPLDRPHSHDLL----------NHEMVKKFSQYDSS-YFE
26687_Tthe       ----IKSKEFIQFVEQCTKINPKERADVVQLL----------ELPFVKTCHGKTA--KLQ
Mek1_Ddis        ----TFSKEFRSFISECLQKEPTERPTASNLL----------NHEFVKKYQNFNVE----
12278_Tthe       ----INSPEFTNFIEICLKSDQNERADITQLLVNTTSFSSFNEHPFLRKIKGKTA--QLK
CC1G_01983_Ccin  --GVNWSEEMKDFIKQALTVDPVDRPTPKDML----------EHPWIKNMMKYEN--TMG
CC1G_14241_Ccin  RQRPGYSPFARDWVNKCMRKDAKERATYKELL----------EHPWLIRNGQVDV--DME


E02D9.1_Cele     NFVN--------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        KFVRKC------------------------------------------------------
MKK2_Scer        RFVKKCWE----------------------------------------------------
PBS2_Scer        EYITERLERRN-------------------------------------------K-----
STE7_Scer        HWCRKIKSKIKEDK----------------------------------------R-----
1557_Tthe        NLLQQYLQHLE-------------------------------------------------
1909_Tthe        EWITKNNLKPAQDKYEPAPVVSTVQNTPYFSHQNPPNQTQQTSNQSYQQIKNHDQINLNQ
26687_Tthe       PIFVKW------------------------------------------------------
Mek1_Ddis        KW----------------------------------------------------------
12278_Tthe       PFFVNW------------------------------------------------------
CC1G_01983_Ccin  RWIAQVWGW-S-------------------------------------------R-----
CC1G_14241_Ccin  GWVRCALDAKE-------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QHNQQNQNGSIQVQQGQNNLSIQQLNSTFRKNSQVQNQQNPVQQQQQQQQQQQLQQNINQ
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        SNIQQQIVQQQVNSQSQQQVQNLIALQQNQQQQQQQQQIQQQQQQMSSQALNSQQLHINT
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NLANQNKSNNNSIYQISPTIHTFRPNQEQESENAQEVDEFINDPNEFYGPSDNKTKGIVH
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QRISSLSDKLAPAAPTAATNTSNSRKSSQILNCNFQEMTITSNEIVDSINSPLPIETSIQ
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NPQIPNQQQNSNSRIKQFQIKNPTNLNIQQINQDNLQRSNQSQIITQQDQNQQNASQNQP
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        IIQKQNIGHHYSASISIGQQQRNSNTPRTSLQYVNNGVQMVQVGYDRMNNSIGVSQIVSP
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QSQLNSQKVSPSQAAEQFQQTASNQMHGNLNSNQSQSVYLQQQHILQQQQFQLNLQKIEQ
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        VTGGASQNNTPKLITPLASSSINNNIQQAQNNYQINNQAQNIDNVVQINPNQQQKFSVPD
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        AQQNINMAPQSNQLAQTKANNLNSQPALELNEANLQQIQSEYYESINNQYDIALIQGVNG
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NLIANQIQEIGQLQNQQYQQQPQQIQYQQINNYSLPPKPLSNQKINTPSNQAHSLSIQKQ
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NSVGSAVNQQVYQNQINQKIIQNQNAANLHQQQLIVQQNIQQQQQLISNQLQQQNSPDYS
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NQFNQIQYQQQNQGMQQFQNMVNKINQQQIVVSQQLIQSQNMAFYQQSQNLTNYNPSVRN
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        IIQSEDLQTEVHKRIEEDHLKLKQLITNDFSQKFVDNLLNSLQIRVKQKIFEQLSSLIEK
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        EYQIEFQVLMNNITNQLFQPPQIQQQQQQQIIQQNAQTQSNQSYQFPPAFINQPSNAFPQ
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QQQVQLQQVTQMQANPQLNINGPLIVNGPEQIPQQVQQIPNNAAATAIRINTNLPQDKNS
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        NTQNSTPLSYKSGSPKQNNSSPITINQNNNLSKQIASQKQNEMQAPQNQQFQQINQANQS
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        TQDQKAVNNNLSINQIQSNTNQITSNNHDELNAQQKLVPQSQNARQVQQPLPIDIVTTQE
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QQQTQQQSIQQQQLLLQQQQQQFMTQSQDVFARERTKQFSQTPQNQATQNVNKNGSYTTS
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        HQQQVQQQKAPSQFNKNATISDDPNKATDFELSKAIQKQLGEQKSTLNQPHTQQQKQQAN
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QVKENDLQFQDQIDLQDNSSGAHPHAATTCPHQATINQLQQSSNNPPQIVNNPNSSKSKL
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        AHQGSNNIENTNNFNNIQHGQQINILNDEVNDTEISVSNNISNDTSPINDEELLPNPVLK
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ------------------------------------------------------------
STE7_Scer        ------------------------------------------------------------
1557_Tthe        ------------------------------------------------------------
1909_Tthe        QNYISTSAQNSQNDHNLQQIVAGNGNQSQSQSNINVNIVGLPKRLTRESIIINNPQQQAE
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ------------------------------------------------------------
CC1G_14241_Ccin  ------------------------------------------------------------


E02D9.1_Cele     ------------------------------------------------------------
F35C8.1_Cele     ------------------------------------------------------------
F35C8.2_Cele     ------------------------------------------------------------
MKK1_Scer        ------------------------------------------------------------
MKK2_Scer        ------------------------------------------------------------
PBS2_Scer        ---------------------------------ILR---ERGENGLSKNV----------
STE7_Scer        ---------------------------------IKR---EALDRA-KLEK----------
1557_Tthe        -----------------------------------L---SYYQFK-QAQA----------
1909_Tthe        LAQNINQQQPAAASQGQIPQQTVNQKVIPVSPNFNSEEAETSKKK-PQFADGTKVVINIQ
26687_Tthe       ------------------------------------------------------------
Mek1_Ddis        ------------------------------------------------------------
12278_Tthe       ------------------------------------------------------------
CC1G_01983_Ccin  ---------------------------------SKK---SRDE---SSSR----------
CC1G_14241_Ccin  ----------------------------------------R-------------------


E02D9.1_Cele     ---NYYQR
F35C8.1_Cele     ----SNNY
F35C8.2_Cele     -------T
MKK1_Scer        -----WKD
MKK2_Scer        --KEKDGI
PBS2_Scer        PALHMGGL
STE7_Scer        KQSERSTH
1557_Tthe        QQAEEQQQ
1909_Tthe        EQNQIKKK
26687_Tthe       --LTIMNE
Mek1_Ddis        TANLKQQQ
12278_Tthe       --MKVVEK
CC1G_01983_Ccin  PGTASGTP
CC1G_14241_Ccin  -AKAGRGR