TESK2_Hsap MDRSKRNSIA-----GF-------------------------------------------
TESK1_Hsap MAGER-PPLR-----GP-------------------------------------------
cdi_Dmel MSLNQHS--------GP-------------------------------------------
TESK1_Mmus MAGER-PPLR-----GP-------------------------------------------
TESK2_Mmus MDRSKRNSIA-----GF-------------------------------------------
Tesk_Spur MNIDEK------------------------------------------------------
AqueK482_Aque MVDSKFS--------A--------------------------------------------
AqueK483_Aque MNFLRRVGRS---SRSPSPLTRGSGNNSPTDDWSNTRSNTGNRSSSSSSGTANRKKEGKE
AqueK484_Aque MTDGVDDTLQLTEAGGLVP-----------------------------------------
*
TESK2_Hsap ----------------------------------------PPR-VERL------------
TESK1_Hsap ---------------------------------------GPGP-GEVP------------
cdi_Dmel ---------------------------------------GPPSEICGLSVDQVDSSAASP
TESK1_Mmus ---------------------------------------GP---GEAP------------
TESK2_Mmus ----------------------------------------PPR-VERL------------
Tesk_Spur ------------------------------------------------------------
AqueK482_Aque ---------------------------------------LPA-QLSSDSD----------
AqueK483_Aque ERKEHSTSGSNMIDGVDDNLQLTEAGCLVPDTPLSPSSPVPPLSIKPHPL---SSS-VSP
AqueK484_Aque ------------------------------DMSLS-PSPVPPISIEPHSL---SSS-VSP
TESK2_Hsap ------------------------------------------EEFEGG-----------G
TESK1_Hsap ------------------------------------------GEGPPG-----------P
cdi_Dmel F-------------------IWPSTAGMCTTATTVTTSTNGDATAEAPVKHQ-------P
TESK1_Mmus ------------------------------------------GEG--------------P
TESK2_Mmus ------------------------------------------EEFEGG-----------G
Tesk_Spur ------------------------------------------------------------
AqueK482_Aque ------------------------------------------DSDYSP-----------P
AqueK483_Aque PNSPGSPTVTISASEKLCKKPHPRSLDM--RKLSIPTSVS-----------LDCIKHN-G
AqueK484_Aque PDSPGPPTVTISASEKLCKKPHPQSLGM--KKLSIPTSASLDCINEYEREKEEEYDSFRV
TESK2_Hsap GGEGNVSQVG---------------R-VWPSSYRALISAFSRLTRLDDFTC-EKIGSGFF
TESK1_Hsap GGTG--GGPG---------------R-GRPSSYRALRSAVSSLARVDDFHCAEKIGAGFF
cdi_Dmel LHNG--GWIGNGLPPAPVTRTISSDRLVTGSSCRALRTAVSALYSVDDFVK-EKIGSGFF
TESK1_Mmus GGAG--GGPG---------------R-GRPSSYRALRSAVSSLARVDDFDCAEKIGAGFF
TESK2_Mmus GGDGNTVQVG---------------R-VSSSSYRAIISAFSRLTSLDDFTR-EKIGSGFF
Tesk_Spur ------------------------------------------------------LTAKQR
AqueK482_Aque NSRK--GGTP---------------R-PKSSSFIALKDAVYQLTCLNDFTR-EKIGQGFF
AqueK483_Aque DYDSPAHHVP---------------R-PSSPLLSALREAVESVSNMEDFERIEKIGSGFF
AqueK484_Aque DSDSPSHHVP---------------R-PS-SALRALREAVGSVSNMEDFERIEKIGSGFF
:
TESK2_Hsap S-EVFKVRHRASGQVMALKMNTLS---SNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQ
TESK1_Hsap S-EVYKVRHRQSGQVMVLKMNKLP---SNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQ
cdi_Dmel S-EVYKVTHRTTGQVMVLKMNQLR---ANRPNMLREVQLLNKLSHANILSFMGVCVQEGQ
TESK1_Mmus S-EVYKVRHRQSGQVMVLKMNKLP---SNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQ
TESK2_Mmus S-EVFKVRHRASGQVMALKMNTLS---SNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQ
Tesk_Spur EESKTKIRHKADGRVMVAKIGKQKIWRANQHKMIQELELLNKLQHPNVVRYMGACVKDGH
AqueK482_Aque A-EVFKVTHKNTGEVMVLKLNKSR---NNSKQMLAEIQLLNRLSHSNILGFKGSCVHEGS
AqueK483_Aque A-EVYKVRHKLTDEIMVLKVNKGL---TG-TKTRQEVELLKRLHHPNILHYIGSCIHNGQ
AqueK484_Aque A-DVYKVRRKLTNQIMVLKVNKGL---TA-TKTRQEVELLKRLNHPNILHYIGSCIHNEQ
. *: :: ..:*. *:. : *::*:::* *.*:: : * *:::
TESK2_Hsap LHALTEYINSGNLEQLLDSNL--HLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCL
TESK1_Hsap LHALTEYMNGGTLEQLLSSPE--PLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCL
cdi_Dmel LHALTEYINGGSLEQLLANKE-VVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVL
TESK1_Mmus LHALTEYMNGGTLEQLLSSPE--PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCL
TESK2_Mmus LHALTEYINSGNLEQLLDSDL--YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCL
Tesk_Spur IHPVLEYVSGGCLTDILADES-LALSWRQKGDLATDIARGMTYLHSQNVCHRDLTSANCL
AqueK482_Aque LHALTEYINGGTLEELLSSDP--HLSWSKRIKIAHDIANGMAYLHNRGVFHRDLTSKNCL
AqueK483_Aque LHPLTEFVNGGTLKSLIQDVEKNPFPPEQRIQLSLDMAMGMEYLHNNGMLHRDFNSHNCL
AqueK484_Aque LHPLTEFVNGGTLKSLIQDVEKNPFPREQRIQLSLDMALGMEYLHENGMLHRDFNSNNCL
:*.: *::..* * .:: . :. : :: .:* *: *:* .: ***:.* * *
TESK2_Hsap IKRDEN-GYSAVVADFGLAEK----------------------------------IPDVS
TESK1_Hsap VRREDR-GFTAVVGDFGLAEK----------------------------------IPVYR
cdi_Dmel IRNLANDQYEAVVGDFGLAAK----------------------------------IPVKS
TESK1_Mmus VRREDR-GFTAVVGDFGLAEK----------------------------------IPVYR
TESK2_Mmus IKRDEN-GYSAVVADFGLAEK----------------------------------IPDAS
Tesk_Spur VRQKPNNVLEAILTDFGLARVLGCMPDPPPNSPRTPESPEPDIIDAPNGGPMLPRIPSAC
AqueK482_Aque IQKSDDGSLNCVVADFGLAAK----------------------------------IV---
AqueK483_Aque LRKEGD-RYTAVVADFGLATK----------------------------------NPNLI
AqueK484_Aque LRKEGD-RYTAVVADFGLAAK----------------------------------NPNLM
::. .:: *****
TESK2_Hsap MGS--EKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENF
TESK1_Hsap EGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDF
cdi_Dmel R-K--SRLETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASF
TESK1_Mmus EGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDF
TESK2_Mmus IGR--EKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENF
Tesk_Spur MDVP-RKMSVVGTAFWMAPEVLRGEEYTRQVDVFSFGIVVCEIVARITANPDDLPRTGKF
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque KKLR-RNQSMVGTPYWMAPEVLHGKEYNEKADTYSYGIVLCEIVSRKDADPDEIPRK---
AqueK484_Aque KDLR-CNQSVVGTPFWMAPEVLHGKRYDKKADTYSYGIVLCEIVSRKDADPDEIPRNDNF
TESK2_Hsap GLDYDAFQHM---VG-DCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQEEEQE
TESK1_Hsap GLDVPAFRTL---VGDDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEPAP-
cdi_Dmel GLDYLAFVEL---CPMDTPPVFLRLAFYCCLYDAKSRPTFHDATKKLTLLLEKYEHESS-
TESK1_Mmus GLDVPAFRTL---VGNDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQQPEATP-
TESK2_Mmus GLDYDAFQNM---VG-DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEELE
Tesk_Spur GLDLQLFKEK---CP-GIPEPFLQIAEDCCSMDPRDRPVFAELVRRFEIIRGTLDTETSD
AqueK482_Aque --------------------------------DPDGRPTFDEIVQMLDPLVSAYQSNST-
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque SLNEAAFRELPEVIGSPCPPAFIDLACNCSKFVPDERPGFPIIPH-PPAIMTNLRENYLV
TESK2_Hsap RDRK--LQPTARGLLEKAPGVK--------------------------------------
TESK1_Hsap ---------L-----TRTALTH--------------------------------------
cdi_Dmel ---------AGASPLSSLELINCSPGGSDSENVTLTPRASVPTVATICTAPAGTLTPRHL
TESK1_Mmus ---------LAKPPLTKAPLTY--------------------------------------
TESK2_Mmus RDRK--LQPTAKGPLEKVPGGK--------------------------------------
Tesk_Spur TT-CY------DVNLTDIIRTN----------------------------DS--------
AqueK482_Aque --------PPPAPPIA--PLSN----------------------------------PSSP
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque LLQSLEVDPV-------LPFLY----------------------------AEGL-----L
TESK2_Hsap ------------------------------------------------------------
TESK1_Hsap ------------------------------------------------------------
cdi_Dmel QEVDEDGFRFPSKKS------ASAALPGTPN-----------------------------
TESK1_Mmus ------------------------------------------------------------
TESK2_Mmus ------------------------------------------------------------
Tesk_Spur --DDDD-------------------DDCS-------------------------------
AqueK482_Aque SKVELPAELCPSPQS---------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque TRAEYDRLQSPEMMAQDRKTRADHLLRLLPNKGKNYFQKFCICIGKSGQIELLEKIGFDL
TESK2_Hsap --------RLSSLDDK-IP---------------------------------HKSPCPR-
TESK1_Hsap --------NQGSVARG-GP---------------------------------S-ATLPR-
cdi_Dmel -----GSAGSSGFDDH-ILKSRVRRATQKLEAEILLHRRSLSENIIHFPM--HTSPSDK-
TESK1_Mmus --------NQGSVPRG-GP---------------------------------S-ATLPR-
TESK2_Mmus --------RLSSLDDK-IP---------------------------------HKSPRPR-
Tesk_Spur ---FGFQ-FQTDLDDK-RR---------------------------------SGRTRLRE
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque TLLPAEK-PLRTFENQSGPARESDRLKPVQIHLQGAHFNPVPLIYQETTPTSQGEPTPKT
TESK2_Hsap -----RTIWLSRSQSDIFSRKPPRTVS---------------------------VLDPYY
TESK1_Hsap -----PDPRLSRSRSDLFLPPSPES-----------------------------------
cdi_Dmel ----ARCHQMQRQRSSTHSPTPPRQLSSVQLPATSIPDPPPLPKPVPAVLTLRKVGDPQY
TESK1_Mmus -----PDPRLSRSRSDLFLPPSPES-----------------------------------
TESK2_Mmus -----RTIWLSRSQSDIFSHKPPRTVS---------------------------VLDPYY
Tesk_Spur VLCGCSKGWMTNAEVDEQDCE-KSFVD---------------------------VLKEY-
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ----QRILIL-YSNDPQVSSLPPDVRH---------------------------TQDEYL
TESK2_Hsap RPRDGAA-RTPKVNPFSARQDLMGGKIKFFDLPSKSVIS--LVFDLD---------A---
TESK1_Hsap -PPNWGD-NLTRVNPFSLREDLRGGKIKLLDTPSKPVLP--LVP--P---------S---
cdi_Dmel KPTSEKDHNGSKPNPFEALAQLRGVK-KILDANPKTYAA--GVGDLFSSC--FEMLAPFF
TESK1_Mmus -PPSWGD-NLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVP--P---------S---
TESK2_Mmus QPRDGAT-HTPKVNPFSARQDLKGGKVKFFDLPSKSVIS--LVFDLD---------A---
Tesk_Spur --------------AYAARQYFRV--------VTGFIVC--LLPML--------------
AqueK482_Aque -P------------SSSLLSSLLGGSVERDGIIRERKIS--TVSLDSGCGPERVDPSSYW
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque KRVSDFV-QTLQM--FS--------TVSGTDGRSYSA--YKCIYDVDES---------QR
TESK2_Hsap ------------PGPGT--MPLADWQEPL----APPIRRWRSLPGSPEFLHQEACPFVGR
TESK1_Hsap ------------PFPSTQ-LPLVTTPETLVQP-GTPARRCRSLPSSPELPRRMETALP--
cdi_Dmel KELAAMQSKAGAQGGGTSTEETSTGN--KAS-AAT-PSEPKSLPVSPHMTRKYSAIELRL
TESK1_Mmus ------------PLTSTQ-LPLVTTPDILVQP-ETPVRRCRSLPSSPELPRRMETALP--
TESK2_Mmus ------------PGPGS--TTLADCQEPL----AMSSRRWRSLPGSPEFLHQ-ACPFMGC
Tesk_Spur ----------------------S-------------------------------------
AqueK482_Aque KNI-----------GFYKTPSLTDGK---TTPLTPSSTHFRQISDSSEVSFQLPS-----
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque EHI---------------------------------------------------------
TESK2_Hsap E--------ESLSDGPPPR-LS--SL-------KYRVKEIP-------------------
TESK1_Hsap --------------GPGPPAVG-PSAEEKMECEGSSPEPEP-------------------
cdi_Dmel PQRISNAAPPAVTSAPPPS-IALPT-DE-DDCDDCNSEGEDPDGGGNCADAESSSDDSAV
TESK1_Mmus --------------GPGPSPMG-PT-EERMDCEGSSPEPEP-------------------
TESK2_Mmus E--------ESLSDGPPPR-LS--SL-------KYGVREIP-------------------
Tesk_Spur ------------------------------------------------------------
AqueK482_Aque ---------PSFAWAPPPS-PST-------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ------------------------------------------------------------
TESK2_Hsap --------------------PFR----------------ASALP------------AAQA
TESK1_Hsap --------------------PGP----------------APQLP------------LAVA
cdi_Dmel RPSTVPTARKYRANSLYAHPLFRGSNGTSMKSTSTGEFESPTLLKASASTITLTASVGAT
TESK1_Mmus --------------------PGL----------------APQLP------------LAVA
TESK2_Mmus --------------------PFR----------------TSALS------------AASG
Tesk_Spur ----------------------------------------------------------LW
AqueK482_Aque --------SLYRLSLT---SPID----------------TPSHQ------------VGAS
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ------------------------------------------QN------------FNVW
TESK2_Hsap HE-A--MDCSILQEE----------------------NG---------------------
TESK1_Hsap TD-NFISTCSSASQPWSPRSGPVLNNNPPAVV-VNSPQG---------------------
cdi_Dmel NSCEDLTESARKSKE-QASSGATAAVQALPTP-MSGC-S---------------------
TESK1_Mmus TD-NFISTCSSASQPWSPRSGPPLNNNPPAVV-VNSPQG---------------------
TESK2_Mmus HE-A--MDCSNPQEE----------------------NG---------------------
Tesk_Spur MY-CDLNNVLLWTSLIYASIGLVLENSTRCVEVLHSSQSIFRTLFNLISRLFSRLWNVVS
AqueK482_Aque RE------GSLSSPEHSPITGEDSDHTPSPDP-ISGN-Q---------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque SF-ENLETCDAIILLMSPSIGEVLRGRSPVLE-MEKGVADSHTLINVLPR-----KRVIP
TESK2_Hsap -----FGSRPQG-------------------------------TS---------------
TESK1_Hsap -----WAGEPWNRA-----------------------------QH---------------
cdi_Dmel -----TRLVETPVS-----------------------------VS---------------
TESK1_Mmus -----WAREPWNRA-----------------------------QH---------------
TESK2_Mmus -----FGPRLKG-------------------------------TS---------------
Tesk_Spur LLL----------QRVHCTRSAGSDLN-----------------ENVTYPNQNGGPTKSL
AqueK482_Aque -----FDLEDWNII-----------------------------RA---------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque VYLNMPKVADWLPVFLKSTPSYFIDLLGFQSGMSTVTSEEEFGR----------------
TESK2_Hsap ------------PCP-AG------------------------------------------
TESK1_Hsap ------------SLPRAA------------------------------------------
cdi_Dmel ------------SCTDLELDELKNTCDLNELKNSCEQLPLKTNLTRRDSIESGFFSCFNE
TESK1_Mmus ------------SLPRAA------------------------------------------
TESK2_Mmus ------------LCT-GA------------------------------------------
Tesk_Spur QHGDTPSEVLRNTSTR--------------------------------------------
AqueK482_Aque ------------TCTNMS------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ------------------------------------------------------------
TESK2_Hsap ------------------------------------------------------------
TESK1_Hsap ------------------------------------------------------------
cdi_Dmel ESDAAITNNSFGRQLNGIGSLGFGCGGGGNSSNCCYEKLKTQLMLDACVSADSEINDKLA
TESK1_Mmus ------------------------------------------------------------
TESK2_Mmus ------------------------------------------------------------
Tesk_Spur ------------------------------------------------------------
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ------------------------------------------------------------
TESK2_Hsap ------------------------------------------------------------
TESK1_Hsap ------------------------------------------------------------
cdi_Dmel SLCRCCYYATSTSNAAVTAAAAAAQQQQQSHLLNDTSSTSSSVLLIDNDPAVIGGNTSSS
TESK1_Mmus ------------------------------------------------------------
TESK2_Mmus ------------------------------------------------------------
Tesk_Spur ------------------------------------------------------------
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ----------------------------------------RSYLLLDEDPNL--------
TESK2_Hsap ------------------------------------------------------------
TESK1_Hsap ------------------------------------------------------------
cdi_Dmel TALDSMDDLDADIVASRRTHQRRYTCHHALLSGNGSESQMAATASLINRLALDSEIHTLL
TESK1_Mmus ------------------------------------------------------------
TESK2_Mmus ------------------------------------------------------------
Tesk_Spur ------------------------------------------------------------
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ------------------------------------------------------------
TESK2_Hsap ------------------------------------------------------------
TESK1_Hsap ------------------------------------------------------------
cdi_Dmel QRSPFATNQLLYCKNRTSSIYTDSSDDISSLAGSDSLLWDDRSFTALPSTRSAQIAKIVE
TESK1_Mmus ------------------------------------------------------------
TESK2_Mmus ------------------------------------------------------------
Tesk_Spur ------------------------------------------------------VADLVP
AqueK482_Aque ------------------------------------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque ----------------------------------------------------KEMRDLL-
TESK2_Hsap ASEEMEVEE--------RPAGSTPA-----------------------------------
TESK1_Hsap ALERTE--P--------SPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPTPAVARYR
cdi_Dmel YFERKRQD---------SSPPSVHHRNGNGTVAAAVAASALGSNYLSYESRRYSDFKRHL
TESK1_Mmus ALERTE--P--------SPPPSAPREPEEGLPCPGCCLGPFSFGFLSMCPRPTPAVARYR
TESK2_Mmus ASEEMEVEE--------ERPRRASV-----------------------------------
Tesk_Spur ILKNRQ--K--------GPGPGAEDPESQGARKKTLL----------ANELEETELDKLH
AqueK482_Aque LVEE-EEE---------EGGGGGILTDRDG------------------------------
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque AVLRREPPPENPTTVFAVPPPKSSDLKSQGIPT----------KYLDLVTRMIPHIWDRV
TESK2_Hsap ----------------------------------------------------------TF
TESK1_Hsap NLNC--------------------------------------------EAGSLLCHRGHH
cdi_Dmel NADGL----------------------------------CFDLDKKPAQQRMMVCEGAVK
TESK1_Mmus NLNC--------------------------------------------EAGSLLCHRGHH
TESK2_Mmus ----------------------------------------------------------YF
Tesk_Spur NPNIN----------------------------------------RVLLNGRMSQKRVSF
AqueK482_Aque ---------------------------------------------RER-----IERRPLF
AqueK483_Aque ------------------------------------------------------------
AqueK484_Aque GLKLGFTLMEIESIRSRNKDDPEQSIHSMFSKWQERDGAEATIDILIKVLQELRLNGVVY
TESK2_Hsap -STSGIGLQTQGKQDG
TESK1_Hsap AKPPTPSLQL-PGARS
cdi_Dmel SKLP-IFDKKKQQQGG
TESK1_Mmus AKPPTPSLQL-PGARS
TESK2_Mmus -SISGISLQTQAKQDG
Tesk_Spur -SLQNSIDRDEGDPNP
AqueK482_Aque NR---TSCSTPNLQTC
AqueK483_Aque ---------------L
AqueK484_Aque -KVKAEVEKDKQKEKK