Kinase Family STE11

From WikiKinome
Jump to: navigation, search

Kinase Classification: Group STE: Family STE11

STE11 (MAP3K, MEKK) kinases are part of the MAPK signaling cascades: they are activated by STE20 (MAP4K) and phosphorylate STE7 (MAP2K, MEK) kinases.

The STE11 family has the following subfamilies:

MEKK1

MEKK2

MEKK4

MEKK15

ASK

CDC15

Evolution

STE11 kinases are found in almost all eukaryotes, with Plasmodium being a notable exception.